| Wallace, Mark |
| Completed | 4 | 1014 | US | Enhanced Self-Care (ESC), Acceptance and Commitment Therapy (ACT), Evidence-Based Exercise and Manual Therapy (EBEM), Duloxetine, Cymbalta | University of North Carolina, Chapel Hill, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Chronic Low-back Pain | 07/24 | 10/24 | | |
| Active, not recruiting | 3 | 409 | Europe, US | Qutenza (capsaicin) 8% topical system, capsaicin 0.04% topical system | Averitas Pharma, Inc., Averitas Pharma, Inc. | Post Surgical Neuropathic Pain | 01/25 | 08/25 | | |
NCT05025787: A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain. |
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| Completed | 2 | 77 | US | CNTX-6970, Placebo | Maurizio Fava, MD | Knee Osteoarthritis | 06/24 | 06/24 | | |
NCT06243835: A Study to Test the Effects of Kindolor At Different Doses in Healthy Adults |
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| Active, not recruiting | 1 | 32 | US | Kindolor Tosylate, DCUKA, Placebo, Placebo to Match | Lohocla Research Corporation, National Institute on Drug Abuse (NIDA) | Chronic Pain | 07/25 | 07/25 | | |
NCT06633562: A Study to Test the Effects of Nezavist At Different Doses in Healthy Adults |
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| Not yet recruiting | 1 | 32 | US | Nezavist SDD, DCUK-OEt, Placebo, Microcrystalline Cellulose | Lohocla Research Corporation, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Healthy, Safety Evaluation of Escalating Doses, Tolerability | 09/25 | 12/25 | | |
NCT05438264: Effect of Donepezil on Speech Recognition in Cochlear Implant Users |
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| Recruiting | 1 | 50 | US | Donepezil, Aricept, Placebo | Vanderbilt University Medical Center | Bilateral Sensorineural Hearing Loss | 09/25 | 09/25 | | |
| Martin, Cindy |
GenePHIT, NCT05598333: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects with Non-Ischemic NYHA Class III Heart Failure |
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| Recruiting | 2 | 150 | US | AB-1002, Gene Therapy, NAN-101 | Asklepios Biopharmaceutical, Inc. | Congestive Heart Failure | 10/26 | 12/30 | | |
| Uretsky, Barry F |
| Recruiting | 4 | 7410 | US | Metformin XR, Placebo | VA Office of Research and Development | Prediabetic State, Atherosclerosis, Metformin | 03/29 | 03/29 | | |
| Completed | 3 | 3506 | Europe, Canada, US, RoW | Red Blood Cell Transfusion | Rutgers, The State University of New Jersey, University of Pittsburgh, National Heart, Lung, and Blood Institute (NHLBI) | Myocardial Infarction, Anemia | 05/23 | 10/23 | | |
NCT04224610: The Utility of (Fractional Flow Reserve)FFR Before and After Successful Percutaneous Coronary Intervention |
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| Active, not recruiting | N/A | 700 | NA | | Central Arkansas Veterans Healthcare System | Coronary Artery Disease | 03/15 | 12/24 | | |
| Recruiting | N/A | 2000 | Europe, Canada, US, RoW | | Minneapolis Heart Institute Foundation | Coronary Artery Disease | 01/24 | 01/24 | | |
NCT04221815: IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact |
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| Recruiting | N/A | 3100 | Europe, US, RoW | Eagle Eye Platinum digital IVUS catheter with optional SyncVision, Resolute Onyx Drug Eluting Stent, Onyx Frontier Drug Eluting Stent, Onyx TruStar Drug Eluting Stent, Onyx TruCor Drug Eluting Stent | Medstar Health Research Institute | Atherosclerosis | 04/27 | 08/27 | | |
NCT01952873: Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation |
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| Not yet recruiting | N/A | 40 | US | Prolonged inflation, Rapid inflation | Central Arkansas Veterans Healthcare System | Coronary Artery Disease, Coronary Stent Occlusion | 12/28 | 12/28 | | |
| Mahmud, Ehtisham |
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD) |
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| Active, not recruiting | N/A | 178 | Europe, Canada, US | SAPIEN 3 THV, Optimal Heart Failure Therapy | Cardiovascular Research Foundation, New York, Cardialysis BV, Avania | Aortic Valve Stenosis | 02/23 | 02/25 | | |
NCT06183294: Evaluation of a Novel Non-Invasive Automated Fractional Flow Reserve Software System in Patients With Coronary Artery Disease |
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| Active, not recruiting | N/A | 100 | US | Collecting invasive FFR measurements., Data collection | University of California, San Diego, MedHub-AI | Stable Angina, Unstable Angina, NSTEMI | 08/25 | 08/25 | | |
| Recruiting | N/A | 2000 | Europe, Canada, US, RoW | | Minneapolis Heart Institute Foundation | Coronary Artery Disease | 01/24 | 01/24 | | |
NCT04221815: IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact |
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| Recruiting | N/A | 3100 | Europe, US, RoW | Eagle Eye Platinum digital IVUS catheter with optional SyncVision, Resolute Onyx Drug Eluting Stent, Onyx Frontier Drug Eluting Stent, Onyx TruStar Drug Eluting Stent, Onyx TruCor Drug Eluting Stent | Medstar Health Research Institute | Atherosclerosis | 04/27 | 08/27 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
ECLIPSE, NCT03108456: Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The Trial |
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| Active, not recruiting | N/A | 2005 | US | Orbital Atherectomy, Balloon | Abbott Medical Devices, Cardiovascular Research Foundation, New York | Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction | 06/24 | 06/25 | | |
| Active, not recruiting | N/A | 1720 | Europe, Canada, US | Microport Firehawk stent, MicroPort Firehawk rapamycin target eluting stent, 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent) | Shanghai MicroPort Medical (Group) Co., Ltd. | Coronary Artery Disease | 12/23 | 06/27 | | |
ASPIRE PH, NCT04555161: Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System |
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| Recruiting | N/A | 30 | US | Aria CV Pulmonary Hypertension System, Aria CV PH System | Aria CV, Inc | Pulmonary Arterial Hypertension, Pulmonary Hypertension, Right Heart Dysfunction | 10/25 | 10/26 | | |
NCT03523416: Early Feasibility Study - Edwards APTURE Transcatheter Shunt System |
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| Active, not recruiting | N/A | 71 | US | Transcatheter Atrial Shunt System | Edwards Lifesciences | Heart Failure | 12/23 | 11/28 | | |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |
