| Yee, Raymond |
| Active, not recruiting | 3 | 700 | Europe, Canada, US, RoW | Implantable Cardioverter Defibrillator + Usual Care, Implantable Cardioverter Defibrillator, ICD, Usual care, Standard medical therapy alone | University of Calgary, Canadian Institutes of Health Research (CIHR), Alberta Innovation and Science, Medtronic, GE Healthcare, Cardiac Arrhythmia Network of Canada, Accelerating Clinical Trials Consortium | Myocardial Infarction, Sudden Death | 12/24 | 12/24 | | |
RAFT-PermAF, NCT01994252: Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation |
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| Active, not recruiting | N/A | 200 | Canada | Optimal Medical therapy plus ICD, Optimal Medical therapy plus CRT/ICD | Ottawa Heart Institute Research Corporation, Canadian Institutes of Health Research (CIHR) | Heart Disease, Congestive Heart Failure, Atrial Fibrillation | 09/24 | 09/24 | | |
| Krahn, Andrew D |
TaRGET, NCT06174220: Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy |
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| Not yet recruiting | 2 | 120 | Canada | Tideglusib, Placebo | Hamilton Health Sciences Corporation, Population Health Research Institute, Canadian Institutes of Health Research (CIHR), AMO Pharma, Hearts in Rhythm Organization (HiRO), Canadian SADS | Arrhythmogenic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy | 02/26 | 07/26 | | |
CPVT, NCT06005428: Effectiveness of CRD-4730 in Participants with Catecholaminergic Polymorphic Ventricular Tachycardia |
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| Recruiting | 2 | 12 | Europe, Canada, US | CRD-4730, Placebo | Cardurion Pharmaceuticals, Inc. | CPVT1, Heart Defects, Congenital, Heart Diseases, Ventricular Tachycardia | 07/25 | 09/25 | | |
| Recruiting | N/A | 100 | Canada, US, RoW | Invasive Electrophysiology Study | Western University, Canada, Canadian Institutes of Health Research (CIHR) | Sudden Cardiac Death | 01/25 | 01/25 | | |
| Turkstra, Timothy P |
NCT03992092: Video Stylet vs. Flexible Bronchoscopy for C-Spine |
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| Recruiting | N/A | 50 | Canada | C-MAC VS, Flexible Bronchoscopy | Lawson Health Research Institute | Intubation;Difficult, Intubation Complication | 12/24 | 12/24 | | |
| Jones, Philip M |
TRACTION, NCT04803747: A Trial of a Hospital Policy of Tranexamic Acid Use to Reduce Transfusion in Major Non-cardiac Surgery |
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| Active, not recruiting | 4 | 8440 | Canada | Tranexamic acid (TXA), Placebo (0.9 % Saline) | University of Manitoba, Canadian Institutes of Health Research (CIHR), Health Sciences Centre Foundation, Manitoba, The Ottawa Hospital | Major Non-cardiac Surgeries | 03/24 | 10/24 | | |
CODEX, NCT04289142: Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients |
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| Recruiting | 4 | 2400 | Canada | Dexmedetomidine Hydrochloride Group, Dexmedetomidine Hydrochloride | Sunnybrook Health Sciences Centre, London Health Sciences Centre, University Health Network, Toronto, McMaster University | Delirium, Cognitive Dysfunction, Cognition Disorder, Neurocognitive Disorders, Mental Disorders, Confusion, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Signs and Symptoms, Dexmedetomidine, Hypnotics and Sedatives, Central Nervous System Depressants, Physiological Effects of Drugs, Analgesics, Non-Narcotic, Analgesics, Molecular Mechanisms of Pharmacological Action | 03/26 | 03/26 | | |
| Recruiting | N/A | 65 | Canada | | Western University, Canada | Cesarean Section Complications, Attachment Disorder, Post Operative Recovery | 05/21 | 09/21 | | |
| Dresser, George |
| Withdrawn | 1 | 12 | Canada | 19F Cell Sense-labeled PBMC, MRI | Gregory A. Dekaban, Western University, Canada, Ontario Institute for Cancer Research | Adverse Reaction to Diagnostic Agents and Kits Nos | 06/22 | 12/22 | | |
| Har, Bryan J |
| Active, not recruiting | 3 | 210 | Canada | tissue plasminogen activator, Saline | Population Health Research Institute, Heart and Stroke Foundation of Canada | Myocardial Infarction, Percutaneous Coronary Intervention | 09/24 | 10/24 | | |
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial |
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| Active, not recruiting | N/A | 527 | Europe, Canada, US | Impella CP® placement prior to reperfusion with Primary PCI | Abiomed Inc. | ST Elevation (STEMI) Myocardial Infarction of Anterior Wall | 09/24 | 10/30 | | |
COMPLETE-2, NCT05701358: Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease |
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| Recruiting | N/A | 5100 | Europe, Canada, US | Physiology-guided NCL PCI, Angiography-guided NCL PCI | Population Health Research Institute | Acute Myocardial Infarction, Coronary Artery Disease | 06/28 | 06/28 | | |
NCT05427370: The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C) |
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| Recruiting | N/A | 754 | Europe, Canada, US, RoW | Revascularization by PCI, Revascularization by CABG | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR), Weill Medical College of Cornell University | Coronary Artery Disease, Heart Failure Systolic | 04/29 | 12/29 | | |
| Silverman, Michael |
| Recruiting | 4 | 8000 | Europe, Canada, RoW | Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging | University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute | Staphylococcus Aureus Bacteremia | 12/28 | 12/28 | | |
| Active, not recruiting | 3 | 2900 | Canada | Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide | Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc. | COVID-19 | 03/24 | 05/24 | | |
| Recruiting | 3 | 471 | Europe, US, RoW | Namodenoson, CF102, Placebo, Inactive control | Can-Fite BioPharma, CanFite BioPharma Ltd. | Hepatocellular Carcinoma, Cirrhosis | 02/25 | 10/25 | | |
NCT04247542: ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection |
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| Completed | 2 | 53 | US | Ibezapolstat, ACX-362E, Vancomycin, Vancomycin oral | Acurx Pharmaceuticals Inc. | Clostridium Difficile Infection | 10/23 | 11/23 | | |
NCT04781387: Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection |
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| Active, not recruiting | 2 | 108 | Canada, US | CRS3123, Active Comparator | Crestone, Inc, National Institute of Allergy and Infectious Diseases (NIAID) | Clostridioides Difficile Infection | 02/24 | 04/24 | | |
| Recruiting | 2 | 20 | RoW | Namodenoson 25mg, CF102 | Can-Fite BioPharma | Pancreatic Adenocarcinoma, Pancreatic Cancer | 07/26 | 12/26 | | |
| Recruiting | 2 | 114 | Europe, RoW | Namodenoson, CF102, Placebo, Inactive control | Can-Fite BioPharma, CanFite BioPharma Ltd. | NASH - Nonalcoholic Steatohepatitis | 04/25 | 10/25 | | |
NCT04544306: Partial Oral Antimicrobials to Treat Infective Endocarditis in People Who Inject Drugs |
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| Recruiting | N/A | 50 | Canada | Partial oral antimicrobial therapy | Lawson Health Research Institute | Infective Endocarditis | 12/24 | 06/25 | | |
| Recruiting | N/A | 1800 | US | Therapeutic Hypothermia | University of Michigan, Johns Hopkins University, Medical University of South Carolina, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) | Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain | 07/28 | 08/28 | | |
| Prapavessis, Harry |
NCT05170464: The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation |
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| Completed | 2/3 | 7 | Canada | Acute Exercise, Aerobic Exercise, Caffeine Powder, Caffeine Ingestion | Western University, Canada | Acute Exercise, Caffeine Withdrawal, Memory Deficits | 03/22 | 04/22 | | |
NCT04323423: The DURATION Study: reDUcing sedentaRy behAviour to Maintain cogniTIve functiON. |
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| Withdrawn | N/A | 12 | Canada | interrupting sedentary behaviour with light physical activity | Western University, Canada | Sedentary Behavior, Mild Cognitive Impairment, Glucose Intolerance, Overweight and Obesity | 12/25 | 12/25 | | |
NCT05115253: Reducing Sedentary Behaviour in Office Workers With a HAPA mHealth Intervention and a Just In-Time Adaptive Intervention |
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| Not yet recruiting | N/A | 93 | Canada | HAPA behavioural counselling + SMS text message boosters, JITAI, mEMA (ilumivu Inc., Boston, MA, www.ilumivu.com) | Western University, Canada | Sedentary Behaviour, Health Behaviour Change | 03/22 | 06/22 | | |
NCT05216159: Mobile Health-Health Action Process Approach Based Intervention on Sedentary Behaviour and Stress in Office Workers |
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| Completed | N/A | 62 | Canada | HAPA behavioural counselling + weekly HAPA worksheets | Western University, Canada | Sedentary Behavior, Health Behaviour Change, Perceived Stress | 07/22 | 07/22 | | |
NCT05505864: Assessing Sedentary Behaviour in Adults With Type 2 Diabetes - A Randomized Controlled Trial |
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| Recruiting | N/A | 52 | Canada | Health Action Process Approach (HAPA) | Western University | Sedentary Behavior, Diabetes Mellitus, Type 2, Adult ALL | 09/23 | 09/23 | | |
NELIP, NCT06187675: A Nutrition and Exercise Lifestyle Intervention Program Participant Choice Approach |
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| Recruiting | N/A | 120 | Canada | Nutrition and Exercise Lifestyle Intervention Program, NELIP | Western University, Canada | Lifestyle, Healthy, Pregnancy Related, Adherence, Treatment, Nutrition, Healthy, Weight Gain, Maternal | 12/28 | 11/29 | | |
| Bauman, Glenn |
NCT04644822: Safety and Efficacy of [18F]PSMA-1007 Injection in Suspected Persistent or Recurrent Prostate Cancer. |
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| Completed | 3 | 100 | Canada | [18F] PSMA-1007 Injection | Centre for Probe Development and Commercialization, McDougall Scientific Ltd. | Prostate Cancer Recurrent, Recurrent Prostate Cancer | 01/24 | 01/24 | | |
| Active, not recruiting | 2 | 12 | Canada | 177Lu-PNT2002, [Lu-177]-PNT2002 Injection, High Dose Radiation | Glenn Bauman, London Health Sciences Foundation | Prostate Cancer | 09/23 | 12/24 | | |
NCT04530513: ARREST - A Phase I Study of SABR for Poly-metastatic Disease |
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| Active, not recruiting | 1 | 48 | Canada | Stereotactic ablative radiotherapy - Level 1, Stereotactic ablative radiotherapy - Level 2, Stereotactic ablative radiotherapy - Level 3, Stereotactic ablative radiotherapy - Level 4, Stereotactic ablative radiotherapy - De-escalation Level | Lawson Health Research Institute, Ontario Institute for Cancer Research | Metastatic Cancer | 06/23 | 06/25 | | |
NCT04670016: HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers |
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| Recruiting | N/A | 57 | Canada | This study does not include an intervention. | University of Calgary, University of Toronto, Université de Montréal, University of Ottawa, Western University, Canada, McMaster University, Alberta Children's Hospital, Stollery Children's Hospital, British Columbia Children's Hospital, CancerCare Manitoba, Children's Hospital of Eastern Ontario, The Hospital for Sick Children, McMaster Children's Hospital, Children's Hospital Medical Center, Cincinnati, St. Justine's Hospital, Montreal Children's Hospital of the MUHC, IWK Health Centre, Janeway Children's Health and Rehabilitation Centre, Princess Margaret Hospital, Canada, London Health Sciences Centre, The Ottawa Hospital, CHU de Quebec-Universite Laval | DIPG, Brain Tumor, Pediatric, Recurrent, Brain Tumor, DIPG, Radiation Toxicity, Radiation Exposure, Brain Tumor, Pediatric | 07/23 | 12/23 | | |
| Completed | N/A | 52 | Canada | Imaging Panel | Lawson Health Research Institute, Canadian Institutes of Health Research (CIHR) | Prostate Cancer | 06/18 | 06/23 | | |
NCT03718260: PSMA-PET Registry for Recurrent Prostate Cancer |
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| Recruiting | N/A | 3070 | Canada | [18F]-DCFPyL PET/ CT scan (PSMA PET) | Lawson Health Research Institute, Cancer Care Ontario, Centre for Probe Development and Commercialization | Recurrent Prostate Cancer | 03/24 | 12/25 | | |
ARGOS/CLIMBER, NCT05269550: PSMA MRI Guided Prostate SBRT (ARGOS)/Comprehensive, Longitudinal Evaluation of Imaging Biomarkers Post Radiotherapy (CLIMBER) |
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| Recruiting | N/A | 50 | Canada | High Intermediate Risk Patients, High Risk or Very High-Risk Patients | Lawson Health Research Institute | Prostate Cancer | 06/24 | 06/28 | | |
| Lemon, Peter WR |
NCT04458493: Does Meal Replacement With a Carbohydrates and Protein Supplement Induce Weight Loss in Overweight and/or Obese Adults? |
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| Not yet recruiting | N/A | 50 | NA | satiety, Dietary Supplement: Generation UCAN supplementation | Western University, Canada | Weight Loss | 01/21 | 07/21 | | |
NCT04576026: Exogenous Ketone Supplementation and Cognitive Function During Exercise |
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| Not yet recruiting | N/A | 15 | Canada | mental fatiguing task, 45 - minute simulated soccer game, cognitive function | Western University, Canada | Ketonemia, Mental Fatigue, Ketosis | 10/21 | 10/21 | | |
| Not yet recruiting | N/A | 30 | Canada | Exercise Adherence | Western University, Canada | Exercise Adherence, Physical Activity Enjoyment, Cardiometabolic Health, Cardiovascular Health | 01/22 | 08/22 | | |
| Jairath, Vipul |
| Recruiting | 4 | 304 | Europe, Canada, US, RoW | Vedolizumab | Alimentiv Inc., Takeda | Moderately to Severely Active Crohn's Disease, Crohn Disease, Disease Crohn | 01/27 | 09/28 | | |
| Active, not recruiting | 4 | 672 | Europe, Canada, US, RoW | Treatment Algorithm A, vedolizumab, Treatment Algorithm B, Treatment Algorithm C | Alimentiv Inc., Takeda Development Center Americas, Inc. | Colitis, Ulcerative | 03/26 | 03/26 | | |
| Active, not recruiting | 4 | 334 | Europe, Canada, RoW | 5-ASA Withdrawal | Alimentiv Inc., Academic Medical Organization of Southwestern Ontario | Crohn Disease, Remission | 06/26 | 06/26 | | |
NCT06045754: A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease |
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| Recruiting | 4 | 150 | Canada, US | Vedolizumab, Entyvio, Adalimumab, Humira, Ustekinumab, Stelara | Takeda | Crohn's Disease | 06/27 | 06/27 | | |
NCT06095128: A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC) |
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| Recruiting | 4 | 65 | Canada, US | Vedolizumab, Entyvio, MLN0002, Tofacitinib, Xeljanz, CP-690, CP-550 | Takeda | Ulcerative Colitis | 07/27 | 07/27 | | |
LUCENT-URGE, NCT05767021: A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis |
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| Active, not recruiting | 3 | 160 | Europe, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis, Ulcerative Colitis Chronic | 08/24 | 09/25 | | |
| Recruiting | 3 | 1063 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis | 07/26 | 12/27 | | |
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NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease |
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| Recruiting | 2 | 268 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Crohn's Disease | 09/26 | 07/27 | | |
NCT06254950: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis |
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| Recruiting | 2 | 207 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Ulcerative Colitis | 09/26 | 08/27 | | |
| Completed | N/A | 600 | Canada | Intervention Group, Control Group | Ottawa Hospital Research Institute, Health Sciences Centre, Winnipeg, Manitoba, Western University, Canada, University of Toronto, Hamilton Health Sciences Corporation, Thunder Bay Regional Health Sciences Centre, Eastern Health, McGill University Health Centre/Research Institute of the McGill University Health Centre, Providence Health & Services, Royal Jubilee Hospital, University of Alberta, MOUNT SINAI HOSPITAL, Nova Scotia Health Authority | Inflammatory Bowel Diseases, Colonic Neoplasms, Dysplasia | 09/22 | 10/22 | | |
INHERIT, NCT04109300: Preemptive HLA Genotyping for the Safe Use of Infliximab-combination Therapy in Inflammatory Bowel Disease |
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| Not yet recruiting | N/A | 162 | Canada | HLADQA1*05A>G screening, Standard of Care | Western University, Canada | Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease | 09/23 | 09/23 | | |
VOICE, NCT06249555: -Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study |
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| Recruiting | N/A | 300 | Canada, US | Vedolizumab (VDZ), Entyvio, Ustekinumab (UST), Stelara, Risankizumab (RISA), Skyrizi | Alimentiv Inc., Takeda | Crohn's Disease | 06/26 | 12/26 | | |
NCT06670638: Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants with Permanent Ileostomy |
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| Not yet recruiting | N/A | 50 | NA | | Alimentiv Inc., University of Western Ontario, Canada, The Leona M. and Harry B. Helmsley Charitable Trust, OPEN Health, The Cleveland Clinic | Crohns Disease | 03/26 | 11/26 | | |
| Recruiting | N/A | 1952 | Canada | Standard colonoscopy with targeted biopsies | Ottawa Hospital Research Institute | Colonic Neoplasms, Inflammatory Bowel Diseases, Dysplasia | 12/25 | 02/26 | | |
| Alvarez, Liliana |
NCT03195608: Using Advanced Driver Assistance Systems (ADAS) as an Intervention Strategy for Drivers With Parkinson's Disease |
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| Completed | N/A | 22 | Canada | Lane change assistance system, Active Control, Simulator practice | Western University, Canada | Parkinson Disease, Driving Impaired | 12/22 | 12/22 | | |
NCT06303765: Evaluating the Practice Resource for Driving After Stroke |
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| Recruiting | N/A | 8 | Canada | Practice Resource for Driving After Stroke (PReDAS) | Western University, Canada | Stroke, Acute, Driving, Occupational Therapy | 07/24 | 08/24 | | |
| Completed | N/A | 103 | Canada | High Alert, Information condition, No contact | Western University, Canada | Cannabis, Youth Drinking | 09/24 | 09/24 | | |
| Mitchell, Marc |
NCT05294692: An Incentive-based mHealth Application for Physical Activity |
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| Completed | N/A | 46 | Europe | Financial Health Incentives | Western University, Canada | Physical Inactivity, Healthy Eating | 12/22 | 12/22 | | |
NCT06023342: Examining Engagement Predictors of Health and Fitness App Uptake and Subscription in the General Population |
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| Active, not recruiting | N/A | 1084 | Canada | | Western University, Canada, Social Sciences and Humanities Research Council of Canada | Physical Inactivity, Healthy Eating, Mental Health Wellness 1 | 12/24 | 12/24 | | |
| Burrows, Patricia |
| Active, not recruiting | 3 | 700 | Europe, Canada, US, RoW | Implantable Cardioverter Defibrillator + Usual Care, Implantable Cardioverter Defibrillator, ICD, Usual care, Standard medical therapy alone | University of Calgary, Canadian Institutes of Health Research (CIHR), Alberta Innovation and Science, Medtronic, GE Healthcare, Cardiac Arrhythmia Network of Canada, Accelerating Clinical Trials Consortium | Myocardial Infarction, Sudden Death | 12/24 | 12/24 | | |
| Dickey, James P |
NCT04708522: Breath Control and Mindfulness for Post Concussion Anxiety and Depression: a Feasibility Study |
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| Not yet recruiting | N/A | 30 | Canada | Breath Control - Equal Breathing Technique, Guided Mindfulness Exercise, Control | Western University, Canada | Post-Concussion Syndrome, Anxiety Disorders and Symptoms, Depressive Symptoms | 05/21 | 07/21 | | |
| Dillon, Kirsten H |
NCT03733028: Mobile Intervention for Veterans With PTSD and Anger |
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| Completed | N/A | 36 | US | Mobile Intervention for Reducing Anger (MIRA), Mindfulness Intervention | VA Office of Research and Development | Posttraumatic Stress Disorder, Anger | 04/23 | 06/23 | | |
NCT04881903: Developing a Mobile Intervention to Reduce Suicidal Cognitions in Veterans |
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| Completed | N/A | 10 | US | Mobile Intervention for Suicidal Thoughts (MIST), Mobile Intervention for Reducing Anger (MIRA) | VA Office of Research and Development | Suicide | 02/24 | 02/24 | | |
| Not yet recruiting | N/A | 50 | US | Safety planning, Treatment as usual, MIST Intervention | VA Office of Research and Development | Suicide | 12/26 | 09/27 | | |
| Not yet recruiting | N/A | 150 | US | Mobile Anger Reduction Intervention (MARI), Health Education Condition (HED) | VA Office of Research and Development | Posttraumatic Stress Disorder, Anger | 10/27 | 03/28 | | |
| Colonna, Robert |
NCT03195608: Using Advanced Driver Assistance Systems (ADAS) as an Intervention Strategy for Drivers With Parkinson's Disease |
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| Completed | N/A | 22 | Canada | Lane change assistance system, Active Control, Simulator practice | Western University, Canada | Parkinson Disease, Driving Impaired | 12/22 | 12/22 | | |
| Bergeron, Celine |
RSV OA=ADJ-023, NCT05921903: A Study on the Immune Response and Safety of an RSV Vaccine When Given to Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant and Are at an Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease and Compared to Healthy Adults 50 Years of Age and Above |
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| Active, not recruiting | 2 | 387 | Europe, Canada, Japan, US, RoW | RSVPreF3 OA Investigational Vaccine | GlaxoSmithKline | Respiratory Syncytial Virus Infections | 07/24 | 06/25 | | |
NCT06592768: A Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety and Efficacy of Briquilimab in Participants with Allergic Asthma |
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| Recruiting | 1 | 30 | Canada | Briquilimab, JSP191, Placebo Comparator | Jasper Therapeutics, Inc. | Allergic Asthma | 03/25 | 09/25 | | |
| Recruiting | N/A | 714 | Canada | | University of British Columbia, University of Alberta, University of Toronto, Laval University, McGill University, Université de Sherbrooke, The Ottawa Hospital, Queen's University, University of Saskatchewan, Western University, Canada | Severe Asthma | 12/27 | 12/28 | | |
| Schabrun, Siobhan M |
| Completed | N/A | 159 | US, RoW | Injection of Nerve Growth Factor | University of Maryland, Baltimore, Neuroscience Research Australia | TMD | 10/22 | 10/22 | | |
NCT05840354: RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain |
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| Recruiting | N/A | 40 | Canada | Magstim Rapid2, rTMS, Placebo D70mm Air Film Coil, sham rTMS | London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's, Western University, Canada, St. Joseph's Health Care London | Chronic Spinal Pain | 07/25 | 12/25 | | |
NCT05975606: Non-invasive Brain Stimulation Paired With FES Cycling Post SCI |
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| Recruiting | N/A | 14 | Canada | repetitive transcranial magnetic stimulation (rTMS), functional electrical stimulation (FES) cycling | Western University, Canada | Incomplete Spinal Cord Injury | 05/24 | 05/24 | | |
NCT06228573: Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis |
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| Recruiting | N/A | 68 | Canada | Yoga | McMaster University, The Arthritis Society, Canada | Knee Osteoarthritis | 09/25 | 12/25 | | |
| Hiemstra, Madison S |
NCT05294692: An Incentive-based mHealth Application for Physical Activity |
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| Completed | N/A | 46 | Europe | Financial Health Incentives | Western University, Canada | Physical Inactivity, Healthy Eating | 12/22 | 12/22 | | |
| Guobadia, Bobby |
CPVT, NCT06005428: Effectiveness of CRD-4730 in Participants with Catecholaminergic Polymorphic Ventricular Tachycardia |
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| Recruiting | 2 | 12 | Europe, Canada, US | CRD-4730, Placebo | Cardurion Pharmaceuticals, Inc. | CPVT1, Heart Defects, Congenital, Heart Diseases, Ventricular Tachycardia | 07/25 | 09/25 | | |
