| Sebbane, Mustapha |
PETEChIA, NCT03780062: Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet |
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| Recruiting | 3 | 720 | Europe | S100B protein dosing | Poitiers University Hospital | Minor Traumatic Brain Injury, Treatment by Antiplatelet | 07/25 | 01/26 | | |
RIVACAST, NCT06195540: RIVAroxaban Versus Low-molecular Weight Heparin in Patients with Lower Limb Trauma Requiring Brace or CASTing |
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| Recruiting | 3 | 1424 | Europe | Rivaroxaban 10 MG, Low Heparin Molecular Weight | University Hospital, Angers | Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma, Thromboprophylaxis, Immobilisation | 11/26 | 11/26 | | |
| Recruiting | 3 | 650 | Europe, Canada, RoW | Alteplase, Placebo | Assistance Publique - Hôpitaux de Paris, Johannes Gutenberg University Mainz, Life Sciences Research Partners (D Collen Research Foundation), Canadian Institutes of Health Research (CIHR), Instituto de Salud Carlos III, International Network of VENous Thromboembolism Clinical Research Networks, Boehringer Ingelheim | Pulmonary Embolism | 09/25 | 08/27 | | |
| Recruiting | N/A | 984 | Europe, RoW | Transcranial Doppler (TCD) | University Hospital, Grenoble | Mild Traumatic Brain Injury | 05/25 | 07/26 | | |
NCT06040736: Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department |
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| Recruiting | N/A | 156 | Europe | | University Hospital, Montpellier | Acute Kidney Injury, Urinary Tract Obstruction | 09/23 | 09/23 | | |
HIFLOWED, NCT04607967: HFNO or Conventional Oxygen Therapy for Patients With Acute Hypoxemic Respiratory Distress |
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| Recruiting | N/A | 500 | Europe | High Flow Nasal Oxygen, HNFO (High Flow Nasal Oxygen) | Centre Hospitalier Universitaire de Besancon, Centre Hospitalier Universitaire Dijon, centre Hospitalier Intercommunal de Vesoul, Centre Hospitalier Universitaire de Saint Louis APHP, Poitiers University Hospital, University Hospital, Clermont-Ferrand, Rennes University Hospital, Centre Hospitalier of Chartres, University Hospital, Toulouse, University Hospital, Montpellier | Acute Hypoxemic Respiratory Distress | 05/25 | 06/25 | | |
HiCOPD, NCT06114667: Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis |
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| Not yet recruiting | N/A | 174 | Europe | Ventilatory support via nasal high flow, Ventilatory support via NIV | University Hospital, Montpellier, Fisher and Paykel Healthcare | Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Hypercapnic Acidosis, Respiratory Failure With Hypercapnia | 05/26 | 06/26 | | |
| RENARD, Eric |
ISLET CHIP, NCT03067324: Quality Control of Pancreatic Islet Intended to Islet Graft Cells Intended to Stabilot Islet Graft Protocol |
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| Recruiting | N/A | 40 | Europe | | University Hospital, Grenoble, University Hospital, Bordeaux | Pancreatic Islet Quality Control | 12/20 | 07/21 | | |
| Active, not recruiting | N/A | 122 | Europe | Closed-loop insulin infusion driven by continuous glucose monitoring through an algorithm, in free-life conditions, Artificial pancreas | University Hospital, Montpellier | Type 1 Diabetes Mellitus in Prepubertal Children | 09/22 | 05/23 | | |
| Recruiting | N/A | 72 | Europe | Closed-loop insulin infusion driven by continuous glucose monitoring through an algorithm, in free-life conditions, Artificial Pancreas, Continuous Subcutaneous Insulin Infusion and Continuous Glucose Monitoring, Sensor Augmented Pump, CSII and CGM | University Hospital, Montpellier, Tandem Diabetes Care, Inc., DexCom, Inc., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Virginia | Type 1 Diabetes Mellitus With Hypoglycemia | 11/22 | 02/23 | | |
| Completed | N/A | 304 | Europe | assessment of biomarkers of insulin resistance | University Hospital, Montpellier, Centre National de la Recherche Scientifique, France, Sys2Diag, Mixt laboratory CNRS/Alcediag, Montpellier | Insulin Resistance | 09/23 | 07/24 | | |
| Active, not recruiting | N/A | 200 | Europe, US | Omnipod 5 System | Insulet Corporation | Type 1 Diabetes | 09/23 | 01/25 | | |
NCT02808572: New Biomarkers of Bone Mineral Metabolism as Cardiovascular Risk Factors in Chronic Kidney Disease Patients |
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| Recruiting | N/A | 250 | Europe | Plasma osteoprotegerin level, Plasma fibroblast growth factor 23 level, Vascular calcification score | University Hospital, Montpellier | Chronic Kidney Disease | 03/24 | 06/31 | | |
NCT05597605: The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects |
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| Completed | N/A | 6 | Europe | The SHINE SYSTEM | Indigo Diabetes NV | Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Ketoacidosis, Diabetic, Hyperglycaemia (Diabetic), Hypoglycemia | 12/23 | 01/24 | | |
| Active, not recruiting | N/A | 200 | Europe | Omnipod 5 System | Insulet Corporation | Diabetes Mellitus, Type 1 | 08/24 | 08/25 | | |
TELXCODIA, NCT04769765: Feasability of a Care Pathway Integrating Collaborative Tele-expertise to Prevent Recurring Hospitalisations for Diabetic Patients |
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| Recruiting | N/A | 200 | Europe | Definition of the Individualized Care Pathway | Centre Hospitalier Universitaire de Nīmes, University Hospital, Montpellier, Hospital Center, Alès, CH Bagnols sur Cèze, CH Béziers, HOPITAL ST CLAIR HBT SETE, Centre Hospitalier Saint Jean Perpignan, CH Narbonne HÔTEL DIEU | Diabetes Mellitus | 05/24 | 05/24 | | |
APATDIAGNOSIS, NCT06283797: Efficacy of Automated Insulin Therapy Early Initiated After Diagnosis on Blood Glucose Control in Children and Adolescents with Type 1 Diabetes |
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| Recruiting | N/A | 112 | Europe | OmniPod 5, Dexcom G6, PAID questionnaires | University Hospital, Montpellier, Hopital Universitaire Robert-Debre, University Hospital, Tours, University Hospital, Angers, University of Virginia | Diabetes | 06/26 | 06/27 | | |
NCT06738849: EkiYou-Study-2 : a National Multicentric Trial of the EkiYou Application for Insulin Bolus Calculation |
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| Recruiting | N/A | 154 | Europe | EkiYou V2 | DiappyMed, Sanoia | Diabetes Type 1, Diabetes Type 2 on Insulin, Pancreatogenous Diabetes | 05/25 | 11/25 | | |
| COLBUS, Laurent |
IRON KID, NCT03231085: Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child |
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| Completed | N/A | 100 | Europe | Ferrous fumarate or ferrostrane, Intravenous ferric carboxymaltose. | University Hospital, Montpellier | Craniosynostosis | 04/24 | 10/24 | | |
| Belzeaux, Raoul |
GROUP, NCT06297252: Prevalence of Psychiatric Disorders During Pregnancy at 2nd Trimester Ultrasound: a Feasibility Study in the General Population |
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| Recruiting | N/A | 140 | Europe | standardized clinical psychiatric evaluations, self-administered psychiatric questionnaire assessments, blood sampling | University Hospital, Montpellier, Beziers Hospital | Pregnancy | 04/26 | 10/26 | | |
| Not yet recruiting | N/A | 255 | Europe | Clinical, cognitive and biological tests, Blood sample collection, Cerebral MRI exam | Assistance Publique Hopitaux De Marseille | Stress Disorders, Post-Traumatic, Depressive Disorder, Major, Anxiety Disorder | 08/25 | 08/25 | | |
| Quere, Isabelle |
| Completed | 3 | 1766 | Europe, Canada | Apixaban 5 MG, Apixaban 2.5 MG | Assistance Publique - Hôpitaux de Paris, Bristol-Myers Squibb | Cancer-associated Thrombosis | 09/24 | 10/24 | | |
| Recruiting | 3 | 250 | Europe | Sirolimus, Rapamycine | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Vascular Malformations | 04/25 | 04/30 | | |
BAT-VTE, NCT05627375: Best Antithrombotic Therapy in Patients With Acute Venous ThromboEmbolism While Taking Antiplatelets |
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| Recruiting | 3 | 1400 | Europe | Full-dose anticoagulant therapy (AC), Antiplatelet therapy (AP) | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Venous Thromboembolic Disease | 12/27 | 12/28 | | |
NCT03492476: Circaid® Compression Sleeve Versus Short-stretching Bandage in Upper Limb Lymphatic Edema |
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| Completed | N/A | 142 | Europe | Circaid, Non-elastic bands, Short-stretching Bandage (Reference treatment) | CEN Biotech, medi | Lymphedema of Upper Arm | 03/22 | 03/22 | | |
| Completed | N/A | 466 | Europe | Colour doppler ultrasound with or without D-dimer test | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer, Centre Hospitalier Universitaire de Saint Etienne, Investigation network on venous thrombo-embolism | Deep Vein Thrombosis | 01/23 | 01/23 | | |
LYMphoNIGHT, NCT04203069: Auto-Adjustable MOBIDERM® Autofit NIGHT-time Compression Armsleeve in the Upper Limb LYMphedema in Maintenance Phase |
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| Completed | N/A | 63 | Europe, RoW | Control group : Day-time compression sleeve, Intervention group : Day-time compression sleeve and Night-time MOBIDERM® Autofit | Thuasne, International Clinical Trials Association | Lymphedema of Upper Arm | 12/23 | 09/24 | | |
| Active, not recruiting | N/A | 340 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Ehlers-Danlos Syndrome, Vascular Type | 01/28 | 01/28 | | |
| Recruiting | N/A | 60 | Europe | Patients will undergo a lower limb MRI and blood tests | University Hospital, Montpellier | Lower Limb Chronic Oedema | 01/24 | 07/25 | | |
ETHER, NCT06731244: Shared Decision-making Process for Unprovoked VEnous THromboEmbolism Management. ( ) |
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| Not yet recruiting | N/A | 2400 | Europe | Usual Care Group, shared decision-making process | University Hospital, Brest, European Commission | Venous Thromboembolism | 10/28 | 10/28 | | |
| Recruiting | N/A | 400 | Europe | Questionnaire | Hospices Civils de Lyon | Vascular Anomaly, Osler Rendu Disease, Marfan Syndrome or Related, Lymphedema Primary, Arteriovenous Malformations, Cerebrospinal; Disorder | 02/27 | 11/28 | | |
NCT02832245: Computerized Registry of Patients With Venous Thromboembolism (RIETE) |
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| Recruiting | N/A | 120000 | Europe, Japan, US, RoW | | Manuel Monreal | Venous Thromboembolism | 12/26 | 12/27 | | |
| Courtet, Philippe |
| Recruiting | N/A | 80 | Europe | The virtual version of the Social stress task : V-TSST | University Hospital, Montpellier | Past Major Depressive Episode, Euthymic | 01/22 | 01/24 | | |
IBIS, NCT04137458: Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour |
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| Recruiting | N/A | 105 | Europe | Biological analysis | University Hospital, Montpellier | Depression | 07/22 | 07/22 | | |
| Recruiting | N/A | 60 | Europe | Cerebral neuroinflammation evaluation | University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France | Depressive Disorder | 01/24 | 01/24 | | |
G-PACTS, NCT02664701: Cognitive Behavioural Group Therapy Versus Individual Supportive Therapy for the Prevention of Repeat Suicide Attempts |
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| Recruiting | N/A | 240 | Europe | Baseline evaluation with a psychiatrist, Individual supportive therapy, Cognitive behavioural group therapy, Evaluations with a psychiatrist | Centre Hospitalier Universitaire de Nīmes | Suicidal Ideation, Suicide, Attempt | 04/24 | 04/25 | | |
CONVERSTIM, NCT04097184: Efficacy of Dorso-lateral Prefrontal Cortex Stimulation by tDCS in Motor Conversion Disorder Patients |
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| Recruiting | N/A | 96 | Europe | Neurostimulation with non-implanted electrodes | Centre Hospitalier Universitaire de Nīmes | Conversion Disorder | 09/24 | 09/25 | | |
| Recruiting | N/A | 300 | Europe | Shared-decision making process, standard care | Centre Hospitalier Universitaire de Nīmes | Bipolar Disorder | 12/24 | 12/25 | | |
| Recruiting | N/A | 100 | Europe | active tDCS stimulating left DLPFC, Starstim® (Neuroelectrics, Spain), active tDCS stimulating right OFC, sham tDCS | Centre Hospitalier Universitaire de Besancon, Fondation FondaMental | Unipolar Depression, Impulsive Behavior, Suicidal Ideation | 07/25 | 02/26 | | |
| Not yet recruiting | N/A | 255 | Europe | Clinical, cognitive and biological tests, Blood sample collection, Cerebral MRI exam | Assistance Publique Hopitaux De Marseille | Stress Disorders, Post-Traumatic, Depressive Disorder, Major, Anxiety Disorder | 08/25 | 08/25 | | |
| COZE, Carole |
| Recruiting | 3 | 800 | Europe, RoW | Vincristine, L01CA02, Carboplatin, LO1XA02, Etoposide, L01CB01, Vindesine, L01CA03, Dacarbazine, L01AX04, Ifosfamide, Doxorubicin, L01DB01, Busulfan, L01AB01, Melphalan, L01AA03, Thiotepa, L01AC01, Radiotherapy, Dinutuximab Beta, L01XC16, Cisplatin, L01XA01, Temozolomide 100 MG, Irinotecan, Cyclophosphamid | Gustave Roussy, Cancer Campus, Grand Paris, PHRC, Solving Kids' Cancer Europe, Neuroblastoma UK, , BSPHO, Instituto de Investigación Sanitaria La Fe, Deutsche Krebshilfe | High-Risk Neuroblastoma, Patient With Insufficient Response Chemoimmunotherapy | 11/26 | 11/32 | | |
| Recruiting | 2/3 | 225 | Europe | Melphalan or Melphalan + Topotecan, Alkeran, Topotecan Accord; Topotecan Hospira chemotherapy, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, etoposide, carboplatin and vincristine chemotherapy, Carboplatin administered on Day 1, platinum-based chemotherapy, Thermotherapy (local treatment), Thermotherapy after carboplatin administered on Day 1, Cryotherapy (local treatment), Iodine-125 plaques (local treatment), Intravitreal Melphalan chemotherapy injections (local treatment) | Institut Curie, Fondation Rothschild Paris | Retinoblastoma | 01/35 | 01/36 | | |
| Active, not recruiting | 2 | 133 | Europe | VP16, carboplatin, etoposide, vepesid, chemotherapy, Melphalan, Alkeran, chemotherapy, VP16, carboplatin, vincristin, etoposide, vepesid, leurocristine, Oncovin, chemotherapy, Carboplatin + laser day 1 (chemothermotherapy), Carbo-laser, platinum-based chemotherapy, Laser (local treatment), Laser diode, cryoapplication (local treatment), I125 radioactive plaques (local treatment), intravitreal Melphalan (local treatment) | Institut Curie, Fondation Rothschild Paris | Retinoblastoma, Children, Retinal Neoplasm | 01/23 | 09/35 | | |
| Recruiting | 2 | 185 | Europe | Observation, Low risk group, Etoposide, Intermediate risk sub group 1, Vincristine, Intermediate risk sub group 2, Orbital irradiation, High risk group, Carboplatin, Cyclophosphamide, Thiotepa, Cytapheresis, Peripheral bood stem cell transplantation | Institut Curie | Retinoblastoma | 03/30 | 09/30 | | |
COTESARC, NCT04216953: MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma |
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| Active, not recruiting | 1/2 | 320 | Europe | Cobimetinib, GDC-0973, Atezolizumab, RO5541267 | Centre Leon Berard | Sarcoma,Soft Tissue | 02/26 | 02/27 | | |
| Recruiting | N/A | 300 | Europe, RoW | Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available | University Hospital, Angers | Predisposition, Genetic, Cancer Childhood, Development Delay | 02/25 | 08/25 | | |
MICCHADO, NCT03496402: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults |
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| Active, not recruiting | N/A | 600 | Europe | Sampling on blood, bone marrow and cerebrospinal fluid | Institut Curie | Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor | 04/27 | 08/27 | | |
NCT04253015: A Post-Authorisation Safety Study Patient Registry of Patients With Neuroblastoma Being Treated With Dinutuximab Beta |
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| Recruiting | N/A | 125 | Europe | Data-collection | EusaPharma (UK) Limited, United BioSource, LLC | Neuroblastoma | 03/32 | 06/32 | | |
BIOPORTAL, NCT05192980: SIOPEN , An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours |
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| Recruiting | N/A | 600 | Europe | No Intervention NA, Bio-sampling | Institut Curie | Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma | 11/38 | 11/38 | | |
| CAMBONIE, Gilles |
| Active, not recruiting | 2/3 | 824 | Europe | Acetaminophen, NACL 0.9% | Institut National de la Santé Et de la Recherche Médicale, France, UPCET, PARTNERS for International clinical Research, European Fundation for the Care of the Newborn Infants, Connect for Children | Patency of the Ductus Arteriosus, Acetaminophen, Extreme Prematurity | 07/24 | 07/24 | | |
EPIREMED, NCT02757794: Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial |
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| Completed | N/A | 166 | Europe | computerized cognitive remediation program, standard remediation | Assistance Publique Hopitaux De Marseille | Children Born Extremely Premature, Disturbance of Visuo-spatial Working Memory | 08/19 | 08/19 | | |
DIABACT IV, NCT02167802: Construction and Validation of a Tool for Automatic Identification of Care Pathways At Risk of Sub-optimality in the Management of Severe Infections in Children |
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| Completed | N/A | 524 | Europe | | Nantes University Hospital | Severe Infection | 03/20 | 03/20 | | |
EDELVAISS, NCT06656104: Impact of a Multi-infusion Strategy in Neonatology on the Rate of Central Line-associated Bloodstream Infections |
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| Not yet recruiting | N/A | 455 | Europe | Reference strategy, Experimental strategy | Hospices Civils de Lyon | Neonatal Infection | 11/26 | 11/26 | | |
| Recruiting | N/A | 500 | Europe | 2 year follow-up of neurodevelopment using a parental questionnaire | Institut National de la Santé Et de la Recherche Médicale, France | Patency of the Ductus Arteriosus Acetaminophen Extreme Prematurity | 12/26 | 06/27 | | |
| MILESI, Christophe CM |
| Recruiting | N/A | 452 | Europe | Supine position (SP), Prone position (PP) | Hospices Civils de Lyon | Acute Viral Bronchiolitis | 11/22 | 11/22 | | |
| kalfa, nicolas |
NCT02495090: Hypospadias and Exome: Identification of New Genes for Familial Hypospadias |
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| Completed | N/A | 60 | Europe | Exome sequencing | University Hospital, Montpellier | Hypospadias | 11/15 | 04/24 | | |
| Recruiting | N/A | 1200 | Europe | Measure of the exposure of parent of male with /without cryptorchidism to endocrine disruptors | University Hospital, Montpellier, University Hospital, Bordeaux | Cryptorchidism | 10/25 | 10/26 | | |
PROPHYBIOTA, NCT05319067: Study of Gut Microbiota Diversity in Children Aged 1-3 Years on Prolonged Antibiotic Prophylaxis for Grade 3 or Higher Vesicoureteral Reflux Compared With 2 Age-matched Control Groups |
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| Recruiting | N/A | 150 | Europe | Stool sampling | Centre Hospitalier Universitaire de Nīmes | Vesicoureteral Reflux 3 | 11/26 | 11/26 | | |
HYPOLLUT, NCT06628375: A Multimodal Study of the Relationship Between Exposure to Endocrine Disruptors and Occurrence of Hypospadias - |
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| Not yet recruiting | N/A | 200 | NA | Consultation visit (Visit 1) | University Hospital, Montpellier | Hypospadias | 09/27 | 10/27 | | |
KYSTOV, NCT02482467: Prognosis and Long Term Pubertal Outcome of Girls Previously Diagnosed With a Prenatal Ovarian Cyst |
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| Recruiting | N/A | 218 | Europe | Hormonal analysis, pelvic US | University Hospital, Montpellier | Ovarian Cyst | 11/24 | 11/24 | | |
| Recruiting | N/A | 20 | Europe | Identify structural variants by Optical Genome Mapping of DNA extracted from blood leukocytes | University Hospital, Montpellier | Disorder of Sex Development, 46,XY | 06/25 | 06/25 | | |
NCT05184647: Total Splenectomy vs Partial Splenectomy in Non-malignant Hemoglobinopathies : Study Comparing the Effectiveness |
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| Not yet recruiting | N/A | 100 | Europe | | University Hospital, Montpellier | Splenectomy; Status | 06/22 | 12/22 | | |
| GENY, Christian |
LUMA, NCT05348785 / 2021-004849-20: A Study to Learn About the Safety of BIIB122 Tablets and Whether They Can Slow the Worsening of Early-Stage Parkinson's Disease in Adults Between the Ages of 30 and 80 |
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| Recruiting | 2 | 640 | Europe, Canada, Japan, US, RoW | BIIB122, DNL151, BIIB122-Matching Placebo | Biogen, Denali Therapeutics Inc. | Parkinson Disease | 12/25 | 12/25 | | |
AGAPO, NCT03693872: Evaluation of the Nonmotor Symptomatology of Parkinsonian Patients Treated With Two Strategies Related to Apomorphine Pump Therapy in French Hospitals |
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| Completed | N/A | 43 | Europe | Apomorphine, APO, Dopaminergic Agonist + Apomorphine, AGAPO | Rennes University Hospital | Parkinson Disease | 06/22 | 06/22 | | |
NCT03940872: Primary Parkinsonian Pain Diagnostic Questionnaire: Development and Validation of This Questionnaire |
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| Completed | N/A | 227 | Europe | Self-questionnaire 3PDQ | University Hospital, Toulouse | Parkinson Disease | 12/22 | 12/22 | | |
| Completed | N/A | 21 | Europe | Mindfulness based stress reduction | University Hospital, Montpellier, Institut National de Recherche en Informatique et en Automatique, Université Montpellier | Parkinson Disease, Rest Tremor | 10/24 | 10/24 | | |
| Dereure, Olivier |
RITUX-MMP, NCT03295383: Randomized Clinical Trial Comparing the Safety and Efficacy of Rituximab Versus Oral Cyclophosphamide in Severe Forms of Mucous Membrane Pemphigoid |
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| Recruiting | 3 | 130 | Europe | Rituximab 1g IV, Cyclophosphamide 50Mg Oral Tablet, Placebo of Rituximab, Placebo Oral Tablet | University Hospital, Rouen | Severe Forms of Mucous Membrane Pemphigoid | 11/22 | 11/23 | | |
| Active, not recruiting | 2 | 170 | Europe, US | IPH4102, lacutamab | Innate Pharma | Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides/Sezary Syndrome | 10/23 | 01/26 | | |
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| Active, not recruiting | 2 | 271 | Europe | Nivolumab + Ipilimumab, Encorafenib + Binimetinib | European Organisation for Research and Treatment of Cancer - EORTC | Unresectable Stage III Melanoma, Stage IV Melanoma | 10/23 | 01/27 | | |
| Active, not recruiting | 2 | 10 | Europe | Stereotaxic radiosurgery (SRS), Binimetinib Oral Tablet, Mektovi, Encorafenib Oral Capsule, Braftovi, Pembrolizumab, Keytruda | UNICANCER, European Association of Dermato Oncology, Pierre Fabre Medicament, Merck Sharp & Dohme LLC | Malignant Melanoma, BRAF V600 Mutation, Brain Metastases | 04/25 | 04/29 | | |
MelBase, NCT02828202: Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary |
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| Recruiting | N/A | 6000 | Europe | Biological, Tissular, Quality of life | Assistance Publique - Hôpitaux de Paris, National Cancer Institute (NCI) | Malignant Melanoma | 03/24 | 03/24 | | |
NCT05510466: Triple BRAFinh/MEKinh /antiPD1 Combined Therapy in Patients With BRAF Mutated Melanoma With Central Nervous System Metastasis |
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| Recruiting | N/A | 18 | Europe | | University Hospital, Montpellier | Metastatic Melanoma | 02/23 | 03/23 | | |
| Camu, William |
| Recruiting | N/A | 1000 | Europe | biomarkers (composite analysis) | University Hospital, Lille | Amyotrophic Lateral Sclerosis, Motor Neuron Disease | 01/26 | 01/26 | | |
CMT-TOOLS, NCT02596191: Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers |
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| Recruiting | N/A | 80 | Europe | Clinical evaluation, electrophysiological record, Muscle MRI, blood samples analysis | Assistance Publique Hopitaux De Marseille | Charcot-Marie-Tooth Disease Type 1A | 06/26 | 12/27 | | |
| DAUVILLIERS, Yves |
DARIDOR-ALZ, NCT05924425: Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease |
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| Recruiting | 4 | 62 | Europe | Daridorexant 50 mg, Placebo, Polysomnography, Neuropsychological assessment, Questionnaires on sleep and behavioural problems, Actimetrics, 24-hour Ambulatory Blood Pressure Monitoring (ABPM, Biomarker assay | University Hospital, Montpellier, Idorsia Pharmaceuticals Ltd. | Alzheimer Disease, Insomnia Disorder, Sleep | 05/26 | 03/27 | | |
| Completed | 2/3 | 48 | Europe | Sodium Oxybate Oral Solution 500 MG/ML, Placebos | University Hospital, Montpellier | Idiopathic Hypersomnia | 04/23 | 04/23 | | |
SOLR-IH, NCT06590662: Efficacy and Tolerance of Solriamfetol in Patients Affected with Idiopathic Hypersomnia. |
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| Not yet recruiting | 2 | 60 | Europe | Solriamfetol, Placebo | University Hospital, Montpellier | Idiopathic Hypersomnia | 11/26 | 06/27 | | |
| Recruiting | N/A | 40 | Europe | Sympathetic nervous activity measurement | University Hospital, Montpellier | Willis-Ekbom Disease, Restless Legs Syndrome | 10/25 | 10/25 | | |
NCT01823354: Executive Dysfunction in Restless Legs Syndrome: Clinical Correlates and Outcome After Therapeutic Management |
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| Recruiting | N/A | 176 | Europe | Polysomnography, Clinical Scales, Assessment of executive functions, Medical consultation | University Hospital, Montpellier | Restless Legs Syndrome | 05/26 | 05/26 | | |
NCT02878499: Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism? |
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| Recruiting | N/A | 105 | Europe | polysomnography | University Hospital, Strasbourg, France | Autism Spectrum Disorder | 12/22 | 02/23 | | |
Somnobank, NCT03998020: Constitution of a Clinical, Neurophysiological and Biological Cohort for Chronic Sleep Disorders Responsible of Hypersomnolence |
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| Recruiting | N/A | 5000 | Europe | scale of severity, blood sample | University Hospital, Montpellier, INSERM U1061 Montpellier | Somnolence Disorder, Excessive | 06/30 | 06/33 | | |
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis |
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| Completed | N/A | 848 | Europe | Sunrise, polysomnography | Sunrise, ICUREsearch | Obstructive Sleep Apnea | 10/24 | 10/24 | | |
NARCOBIOTE, NCT06292598: Bacterial Translocation and Gut Microbiota in Type 1 Narcolepsy Patients Versus a Control Population |
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| Not yet recruiting | N/A | 120 | Europe | Blood sample, Stool sample, CSF sample | Centre Hospitalier Universitaire de Nīmes | Narcolepsy Type 1, Bacterial Translocation | 09/27 | 09/27 | | |
| Recruiting | N/A | 2000 | Europe | | University Hospital, Montpellier | Restless Legs Syndrome | 09/26 | 09/27 | | |
| Olie, Emilie |
| Recruiting | N/A | 70 | Europe | | University Hospital, Montpellier | Major Depressive Episode | 09/21 | 01/22 | | |
PsyConf, NCT04374643: Descriptive Study of the PSYchological Impact of CONFinement Measures in the General Population |
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| Recruiting | N/A | 500 | Europe | Slef questionnaires fulfilment | University Hospital, Montpellier | Depression, COVID 19 | 12/21 | 12/21 | | |
PURE, NCT02501226: Effectiveness of the First French Psychoeducational Program on Unipolar Depression |
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| Recruiting | N/A | 332 | Europe | Treatment as usual, ENVIE psychoeducational program | University Hospital, Montpellier, Groupe Hospitalier de la Rochelle Ré Aunis, Centre Hospitalier Universitaire de Besancon, Centre Hospitalier Général de Béziers, University Hospital, Clermont-Ferrand, Centre Hospitalier Universitaire de Nice, Centre Hospitalier de l'Agglomération de Nevers, Centre Psychothérapique de Nancy, Hôpitaux à Bron, Assistance Publique - Hôpitaux de Paris, Centre Hospitalier Esquirol, Centre Hospitalier Sainte-Marie, Nice, Centre Hospitalier Universitaire de Nīmes | Unipolar Depressed Outpatients, Mild Severity, Without Psychotic Features | 06/22 | 06/23 | | |
NCT04899609: The Effects of Anger and Joy Expressions on Approach and Avoidance Behaviors in Healthy Volunteers |
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| Recruiting | N/A | 40 | Europe | | University Hospital, Montpellier | Major Depressive Episode | 06/22 | 12/22 | | |
NCT04461327: Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk |
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| Recruiting | N/A | 153 | Europe | Painful stimulations of major depressive patients, Blood sample, Clinical assessment, Social touch | University Hospital, Montpellier, Clinea psychiatrie France | Major Depressive Disorder | 11/24 | 03/25 | | |
| Completed | N/A | 128 | Europe | | University Hospital, Montpellier | Depression - Major Depressive Disorder, Suicide | 09/24 | 09/24 | | |
| ANDRIEU, Jean-Michel |
TELXCODIA, NCT04769765: Feasability of a Care Pathway Integrating Collaborative Tele-expertise to Prevent Recurring Hospitalisations for Diabetic Patients |
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| Recruiting | N/A | 200 | Europe | Definition of the Individualized Care Pathway | Centre Hospitalier Universitaire de Nīmes, University Hospital, Montpellier, Hospital Center, Alès, CH Bagnols sur Cèze, CH Béziers, HOPITAL ST CLAIR HBT SETE, Centre Hospitalier Saint Jean Perpignan, CH Narbonne HÔTEL DIEU | Diabetes Mellitus | 05/24 | 05/24 | | |
| Recruiting | N/A | 850 | Europe | Freestyle Libre Pro iQ | University Hospital, Montpellier | Acute Coronary Syndrome, Continuous Glucose Measurement, Glycemic Variability, Cardiovascular Event | 05/26 | 05/26 | | |
| cock, Valérie Cochen de |
APOMORPHEE, NCT02940912: Effect of Continuous Apomorphine During the Night on Sleep Disorders in Insomniac Patients With Parkinson's Disease |
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| Completed | 4 | 45 | Europe | Apomorphine, Apokinon, Placebo, Physiologic Serum | Clinique Beau Soleil | Parkinson Disease | 01/21 | 04/21 | | |
| Active, not recruiting | 3 | 134 | Europe | Apomorphine, Apokinon, Best Medical Treatment | Rennes University Hospital | Parkinson's Disease | 12/23 | 01/25 | | |
| Recruiting | N/A | 396 | Europe | BeatPark Application, BeatPark Application without synchronized music, BeatPark Application without music | Clinique Beau Soleil, Team Languedoc Mutualité / Nouvelles technologies, University Hospital, Montpellier, Euromov, Montpellier Univeristy, Université de Montréal, AxLR SATT | Parkinson Disease, Walking, Difficulty | 08/24 | 12/24 | | |
| Recruiting | N/A | 90 | Europe | BeatMove Application, BeatMove Application without synchronized music, BeatMove Application without music | Clinique Beau Soleil, Université Montpellier | Obesity, Sedentary Behavior | 11/25 | 11/25 | | |
| BRINGUIER, Sophie SB |
pediaPREM, NCT05681572: Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia |
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| Recruiting | 3 | 1000 | Europe | Midazolam, Dexmedetomidine, Placebo | University Hospital, Montpellier | Anesthesia | 10/26 | 10/27 | | |
NCT04608968: Pediatric Perioperative Satisfaction Questionnaire |
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| Recruiting | N/A | 600 | Europe | | University Hospital, Montpellier, Clinique Saint Roch, Montpellier, Centre Hospitalier Universitaire de Nīmes, University Hospital, Toulouse, University Hospital, Bordeaux, CHU de Lyon, University Hospital, Grenoble, CHU de Nantes | Perioperative, Children, Satisfaction | 12/26 | 12/26 | | |
IRON KID, NCT03231085: Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child |
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| Completed | N/A | 100 | Europe | Ferrous fumarate or ferrostrane, Intravenous ferric carboxymaltose. | University Hospital, Montpellier | Craniosynostosis | 04/24 | 10/24 | | |
| PERNIN, Vincent |
COR-HUM, NCT04026087: Subclass of Donor-specific Antibody as a Risk Factor of Antibody Mediated Rejection in Renal Transplantation |
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| Completed | N/A | 100 | Europe | | University Hospital, Montpellier, Institut National de la Santé Et de la Recherche Médicale, France | Antibody-mediated Rejection | 05/22 | 02/23 | | |
