| Fearon, William F |
| Recruiting | 3 | 445 | RoW | Tenecteplase (1/3 systemic weight based dose), TNKase, Sterile water for injection (WFI) | University of Sydney, Genentech, Inc. | STEMI, Elevated IMR (>32) | 12/24 | 12/26 | | |
NCT03537742: Cardiac Allograft Vasculopathy Inhibition with Alirocumab |
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| Active, not recruiting | 2 | 120 | US | alirocumab, Praluent, placebo | Stanford University, National Heart, Lung, and Blood Institute (NHLBI) | Vasculopathy | 07/25 | 08/25 | | |
FAME 3, NCT02100722: A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease |
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| Active, not recruiting | N/A | 1500 | Europe, Canada, US, RoW | FFR guided PCI, Fractional Flow Reserve-Guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent | Stanford University, VZW Cardiovascular Research Center Aalst, Catharina Ziekenhuis Eindhoven, Golden Jubilee National Hospital, University of California, Irvine, Medtronic, Abbott Medical Devices, Genae, King's College Hospital, London, Houston Methodist DeBakey Heart and Vascular Center, Houston | Coronary Disease, Coronary Stenosis | 12/20 | 12/24 | | |
| Completed | N/A | 888 | Europe, US, RoW | | CoreAalst BV, Abbott Medical Devices | Coronary Artery Disease | 05/24 | 05/24 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Recruiting | N/A | 1924 | Europe, Japan, US, RoW | FFRangio, FFR or NHPR, FFR, iFR RFR, dPR, Pd/Pa | CathWorks Ltd., Cardiovascular Research Foundation, New York | Percutaneous Coronary Intervention | 12/24 | 12/24 | | |
| Recruiting | N/A | 150 | US | HF-OCT Imaging, FFR Pressure Wire, Angiography | Gentuity, LLC | Coronary Stenosis | 12/24 | 12/24 | | |
| Nef, Holger |
TriCLASP, NCT04614402: Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System |
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| Active, not recruiting | N/A | 300 | Europe | Edwards PASCAL Transcatheter Valve Repair System, Edwards PASCAL Precision Transcatheter Valve Repair System | Edwards Lifesciences | Tricuspid Valve Insufficiency | 04/23 | 03/28 | | |
| Active, not recruiting | N/A | 2001 | Europe | QFR-based diagnostic strategy, FFR-based diagnostic strategy | Aarhus University Hospital Skejby, Medis Medical Imaging Systems | Coronary Artery Disease | 07/23 | 12/25 | | |
| Recruiting | N/A | 500 | Europe | IASD Implant | Corvia Medical | Heart Failure | 07/26 | 07/28 | | |
NCT06181240: Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE) |
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| Recruiting | N/A | 400 | Europe | Intravascular lithotripsy | Bolt Medical | Coronary Artery Disease, Coronary Artery Calcification | 04/25 | 03/26 | | |
NCT02710435: REDUCER-I: An Observational Study of the Neovasc Reducer™ System |
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| Active, not recruiting | N/A | 400 | Europe | Reducer System, Reducer | Neovasc Inc., Shockwave Medical, Inc. | Angina Pectoris, Angina Pectoris, Stable, Chronic Stable Angina | 11/23 | 12/28 | | |
| Recruiting | N/A | 1000 | Europe | Edwards PASCAL Transcatheter Valve Repair System and Edwards PASCAL Precision Transcatheter Valve Repair System | Edwards Lifesciences | Mitral Regurgitation, Mitral Insufficiency | 12/25 | 03/31 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
NCT04221815: IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact |
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| Recruiting | N/A | 3100 | Europe, US, RoW | Eagle Eye Platinum digital IVUS catheter with optional SyncVision, Resolute Onyx Drug Eluting Stent, Onyx Frontier Drug Eluting Stent, Onyx TruStar Drug Eluting Stent, Onyx TruCor Drug Eluting Stent | Medstar Health Research Institute | Atherosclerosis | 04/27 | 08/27 | | |
DOUBLE-CHOICE, NCT05036018: RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation |
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| Active, not recruiting | N/A | 836 | Europe | ACURATE neo2, minimalist approach, CoreValve Evolut Pro and Pro+, Standard of care | Leipzig Heart Science gGmbH, Heart Center Leipzig - University Hospital | Aortic Valve Stenosis | 02/25 | 12/33 | | |
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function |
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| Recruiting | N/A | 1252 | Europe, Canada, US | Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump | Abiomed Inc. | Left Ventricular Dysfunction, Coronary Artery Disease | 03/26 | 10/27 | | |
| Recruiting | N/A | 360 | Europe | Transcatheter tricuspid valve treatment (TTVT) | LMU Klinikum, Heart and Diabetes Center North Rhine-Westphalia, University Medical Center Mainz, Heart Center Leipzig - University Hospital, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), University of Leipzig | Heart Failure Attributable to Severe Tricuspid Regurgitation | 03/26 | 03/27 | | |
| Recruiting | N/A | 1054 | Europe | measurement of FFR, measurement of Pd/Pa | Helios Health Institute GmbH, Heart Center Leipzig - University Hospital | Coronary Artery Disease, Coronary Artery Stenoses | 05/26 | 11/26 | | |
| Cheung, Albert T |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Kipperman, Robert |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
NCT03382457: Clinical Study of Edwards Cardioband FIT Valve Repair System |
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| Recruiting | N/A | 55 | US | Transcatheter Tricuspid Valve Repair, Edwards Cardioband Tricuspid Valve Repair | Edwards Lifesciences | Tricuspid Regurgitation | 12/26 | 12/31 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
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| Enrolling by invitation | N/A | 1500 | Canada, US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
| Assmus, Birgit |
NCT01693042 / 2011-000595-33: Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Mortality in Patients With Chronic Post-infarction Heart Failure |
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| Active, not recruiting | 2/3 | 81 | Europe | intracoronary infusion of autologous bone marrow-derived cells, t2c001 | Johann Wolfgang Goethe University Hospital | Heart Failure | 11/22 | 01/25 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
NCT03020043: Evaluation of Longterm Outcome of New York Heart Association Class III Heart Failure Patients Receiving Telemonitoring Using a Pulmonary Artery Pressure Sensor System (CardioMEMS) |
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| Recruiting | N/A | 500 | Europe | | Johann Wolfgang Goethe University Hospital | Chronic Heart Failure | 12/24 | 12/25 | | |
| Kelm, Christiane |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Striler, Kimberly |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Roth, Peter |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Blachutzik, Florian |
NCT04047368: Comparison of Coronary Lithoplasty and Rotablation |
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| Completed | N/A | 70 | Europe | Rotablation, Coronary Lithoplasty | University of Giessen, Else Kröner-Fresenius Stiftung, Bad Homburg, Germany | Coronary Artery Disease, Calcified Atheroma | 06/21 | 06/22 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Booth, Kara |
| Completed | N/A | 15 | US | PerQseal Plus Device, Vascular Closure Device | Vivasure Medical Limited | Percutaneous Large Hole Vascular Closure | 07/22 | 07/22 | | |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
| Active, not recruiting | N/A | 15 | US | DurAVRTM THV System | Anteris Technologies Ltd. | Aortic Stenosis, Symptomatic Aortic Stenosis, Severe Aortic Valve Stenosis, Aortic Valve Calcification | 12/23 | 12/33 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Active, not recruiting | N/A | 25 | US | J-Valve TF System | JC Medical, Inc. | Aortic Valve Disease, Aortic Valve Insufficiency, Aortic Regurgitation | 07/24 | 08/29 | | |
| Recruiting | N/A | 50 | Canada, US | Cephea Mitral Valve System | Abbott Medical Devices | Mitral Regurgitation | 03/26 | 03/31 | | |
NCT05913908: EFS of the DUO System for Tricuspid Regurgitation |
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| Recruiting | N/A | 15 | US | DUO Transcatheter Tricuspid Coaptation Valve System, DUO System | CroiValve Limited | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases | 12/25 | 10/29 | | |
| Recruiting | N/A | 15 | US | Transcatheter Tricuspid Valve Intervention | Jenscare Innovation Inc., Cardiovascular Research Foundation, New York | Tricuspid Regurgitation (TR) | 01/25 | 01/30 | | |
NCT05666713: NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial |
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| Recruiting | N/A | 180 | US | TELLTALE BASILICA procedure | National Heart, Lung, and Blood Institute (NHLBI) | Valvular Heart Disease, Aortic Valve Failure | 03/25 | 03/25 | | |
VISTA-US, NCT05848284: Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( ) |
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| Recruiting | N/A | 30 | US | VDyne Transcatheter Tricuspid Valve Replacement System, VDyne System, VDyne Tricuspid System, VDyne Valve System, VDyne Valve | VDyne, Inc. | Tricuspid Regurgitation, Tricuspid Valve Disease, Tricuspid Valvular Disorders | 11/25 | 11/30 | | |
| Boeder, Niklas |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Keranov, Stanislav |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Feldmann, Korinna |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Papanicolaou, Cherry |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Klär, Annika |
| No trials found |
