| Yeo, Erik |
COBRRA, NCT03266783: Comparison of Bleeding Risk Between Rivaroxaban and Apixaban for the Treatment of Acute Venous Thromboembolism |
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| Recruiting | 4 | 2760 | Europe, Canada, RoW | Apixaban, Eliquis, Rivaroxaban, Xarelto | Ottawa Hospital Research Institute, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, Canadian Institutes of Health Research (CIHR) | Venous Thromboembolism | 12/24 | 12/24 | | |
| Completed | 3 | 1767 | Europe, Canada | Apixaban 5 MG, Apixaban 2.5 MG | Assistance Publique - Hôpitaux de Paris, Bristol-Myers Squibb | Cancer-associated Thrombosis | 09/24 | 10/24 | | |
| Recruiting | 3 | 2700 | Europe, Canada | Rosuvastatin Calcium, Rosuvastatin, Placebo Oral Tablet, Placebo | Ottawa Hospital Research Institute, The Canadian Institutes of Health Research (CIHR) | Venous Thromboembolism, Blood Clot, Post Thrombotic Syndrome | 01/26 | 01/27 | | |
WAVe, NCT03297359: Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism |
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| Terminated | 2 | 92 | Canada | Dalteparin | Ottawa Hospital Research Institute, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network | Cancer, Venous Thromboembolism, Obesity | 11/23 | 11/23 | | |
| Recruiting | N/A | 1276 | Europe, Canada | Limited cancer screening, Limited cancer screening + FDG PET/CT | University Hospital, Brest, Ministry of Health, France, Canadian Institutes of Health Research (CIHR), Ottawa Hospital Research Institute | Embolism and Thrombosis | 09/26 | 09/30 | | |
| Wasowicz, Marcin |
NCT03861026: Cerebral Oximetry to Reduce Organ Dysfunction After Non-cardiac Surgery |
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| Completed | N/A | 101 | Canada | Bilateral NIRS (Masimo, O3TM Regional Oximetry) | University Health Network, Toronto | Cerebral Desaturation, Surgery | 01/23 | 06/23 | | |
| Parotto, Matteo |
NCT03288558: Protective Mechanical VENTilation Strategy in Patients Undergoing CARDiac Surgery |
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| Recruiting | N/A | 310 | Canada | A comprehensive perioperative mechanical ventilation strategy | University Health Network, Toronto | Pulmonary Complications, Cardiac Surgery | 12/21 | 04/22 | | |
| Not yet recruiting | N/A | 200 | Canada | Contactless vital sign information collection | Nuralogix Corporation, University Health Network, Toronto, Hamilton Health Sciences Corporation | Vital Signs | 10/22 | 10/22 | | |
| Recruiting | N/A | 1440 | Europe, Canada, US, RoW | Restrictive Transfusion Strategy, Liberal transfusion strategy | Unity Health Toronto | Disorder, Heart, Postoperative, Cardiac Surgery | 12/25 | 06/26 | | |
| Not yet recruiting | N/A | 3000 | Canada | | University Health Network, Toronto | Extubation | 12/26 | 12/26 | | |
| He, Yan |
nAMD, NCT05461339: TAB014 Compared to Lucentis® in Patients with Neovascular Age-related Macular Degeneration |
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| Active, not recruiting | 3 | 488 | RoW | TAB014 Monoclonal Antibody Injection, TAB014, Ranibizumab Injection [Lucentis], Lucentis | TOT Biopharm Co., Ltd., Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Neovascular Age-related Macular Degeneration | 09/24 | 02/25 | | |
NCT05768503: Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC |
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| Recruiting | 3 | 176 | RoW | Experimental drug, CAP, Control Rx, FOLFIRI+BEV | Sun Yat-sen University | Metastatic Microsatellite-stable Colorectal Cancer | 01/26 | 01/27 | | |
WAVe, NCT03297359: Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism |
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| Terminated | 2 | 92 | Canada | Dalteparin | Ottawa Hospital Research Institute, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network | Cancer, Venous Thromboembolism, Obesity | 11/23 | 11/23 | | |
NCT05148533: A Study of Single Drug TJ011133 and Toripalimab Combine Treatment for Advanced Solid Tumor |
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| Terminated | 1/2 | 7 | RoW | TJ1133 Injection | TJ Biopharma Co., Ltd. | Advanced Solid Tumor | 02/23 | 02/23 | | |
NCT06055023: Study of Tolerability, Safety, and Pharmacokinetics of ZL-82 in Healthy Adult Subjects. |
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| Recruiting | 1 | 58 | RoW | ZL-82 12.5mg, ZL-82 25mg, ZL-82 50mg, ZL-82 100mg, ZL-82 200mg, ZL-82 300mg, ZL-82 450mg, ZL-82 600mg | Chengdu Zenitar Biomedical Technology Co., Ltd | Rheumatoid Arthritis (RA), Inflammatory Bowel Disease - IBD1 | 06/24 | 12/24 | | |
NCT06549959: A Single Dose Study to Investigate the Pharmacokinetics (PK) of Telitacicept Pre-filled Injection and Freeze-dried Powder Injection in Chinese Healthy Subjects |
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| Recruiting | 1 | 248 | RoW | Telitacicept Pre-filled Injection 80mg, Telitacicept Freeze-dried powder Injection 80mg | RemeGen Co., Ltd. | Healthy | 11/24 | 12/24 | | |
NCT06367647: Investigation of the Detection Rate of Pathogenic Viruses in the Feces of Individuals With Non-gastrointestinal Infections |
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| Recruiting | N/A | 2000 | RoW | | Zhujiang Hospital | Virus Infections | 10/25 | 12/25 | | |
NCT06595095: The Correlation Characteristics Between Mental Health and Gut Microbiota of College Students in Qingyuan Vocational Education City |
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| Not yet recruiting | N/A | 600 | RoW | | Zhujiang Hospital | Depression, Anxiety | 05/25 | 09/25 | | |
NCT05638269: A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in China |
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| Recruiting | N/A | 12000 | RoW | no intervention | Zhujiang Hospital, National Natural Science Foundation of China | Essential Hypertension, Liver Cancer, Nasopharyngeal Cancer, Pancreatic Cancer, Lung Cancer, Chronic Kidney Diseases, Acute Coronary Syndrome, Epilepsy, Gastric Cancer, Primary Aldosteronism, Subclinical hypothyroïdism | 12/24 | 12/25 | | |
| Meineri, Massimiliano |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Mashari, Azad |
NCT05025644: Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test |
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| Not yet recruiting | 4 | 60 | NA | Pre and post-CPB Drug: Dobutamine Hydrochloride, Transthoracic or 2D Echocardiogram, Transesophageal Echocardiogram (TEE), Post-CPB Drug: Dobutamine Hydrochloride | University Health Network, Toronto | Hypertrophic Obstructive Cardiomyopathy | 08/24 | 11/24 | | |
NCT04678726: Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax. |
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| Withdrawn | N/A | 730 | NA | Lung ultrasound assessment for ruling out pneumothorax, Portable chest x-ray | University Health Network, Toronto | Pneumothorax, Cardiac Surgery | 01/24 | 12/25 | | |
| Garijo, Jacobo Moreno |
NCT05025644: Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test |
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| Not yet recruiting | 4 | 60 | NA | Pre and post-CPB Drug: Dobutamine Hydrochloride, Transthoracic or 2D Echocardiogram, Transesophageal Echocardiogram (TEE), Post-CPB Drug: Dobutamine Hydrochloride | University Health Network, Toronto | Hypertrophic Obstructive Cardiomyopathy | 08/24 | 11/24 | | |
DO2 and POPCs, NCT05154617: Assessment of Oxygen Delivery as an Early Predictor of Postoperative Pulmonary Complications During One-lung Pulmonary Ventilation in Thoracic Surgery. A Pilot Study |
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| Not yet recruiting | N/A | 60 | NA | Standard surgical monitoring, along with the Flo Trac® system monitoring. | University Health Network, Toronto | Postoperative Pulmonary Complications | 10/22 | 10/23 | | |
NCT04678726: Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax. |
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| Withdrawn | N/A | 730 | NA | Lung ultrasound assessment for ruling out pneumothorax, Portable chest x-ray | University Health Network, Toronto | Pneumothorax, Cardiac Surgery | 01/24 | 12/25 | | |
| Active, not recruiting | N/A | 60 | Canada | Lung ultrasound to detect pneumothorax. | Sunnybrook Health Sciences Centre | Pneumothorax | 03/25 | 09/25 | | |
| Recruiting | N/A | 114 | Canada | Transthoracic Echocardiography (TTE) and Transesophageal Echocardiography (TEE), Transthoracic Echocardiography (TTE), Transesophageal Echocardiography (TEE) | Sunnybrook Health Sciences Centre | Heart Chambers | 03/26 | 06/26 | | |
