| Mueller, Christian |
| Completed | 3 | 226 | Europe, Canada, US, RoW | Bentracimab (PB2452) Infusion | SFJ Pharmaceuticals, Inc. | Hemorrhage, Urgent Surgery, Invasive Procedure | 09/24 | 09/24 | | |
BASEL VIII, NCT01838148: Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia |
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| Recruiting | N/A | 4000 | Europe | | University Hospital, Basel, Switzerland | Coronary Artery Disease, Angina, Stable, Exercise Test, Biological Markers, SPECT | 12/22 | 12/24 | | |
NCT00509080: Prognosis in Asymptomatic Mitral Regurgitation (PAMIR) Study |
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| Active, not recruiting | N/A | 200 | Europe | | University Hospital, Basel, Switzerland, Schweizerische Herzstiftung | Mitral Regurgitation | 12/23 | 12/23 | | |
| Active, not recruiting | N/A | 3500 | Europe, US, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Syncope | 12/23 | 12/23 | | |
NCT03660969: Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease |
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| Recruiting | N/A | 800 | Europe | | Christian Müller, MD, Cantonal Hospital of Aarau, Switzerland, Medical University Innsbruck, University Hospital, Zürich, University Hospital Inselspital, Berne | Myopathy, Muscle Weakness, Muscle Damage, Muscle Spasticity, Muscle Cramp, Muscle Injury, Muscle Soreness, Muscle Atrophy | 01/25 | 01/27 | | |
| Recruiting | N/A | 10000 | Europe, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Myocardial Infarction, Angina, Unstable | 06/25 | 06/25 | | |
| Recruiting | N/A | 6000 | Europe | medical chart review, data generated by direct IT export | University Hospital, Basel, Switzerland | Acute Heart Failure, Acute Coronary Syndrome, Heart Failure | 07/27 | 07/27 | | |
| Sticherling, Christian |
| Recruiting | 3 | 416 | Europe | Colchicine, Placebo | University Hospital, Basel, Switzerland, Swiss Heart Foundation, Fondation Machaon, Switzerland, Genf, Foundation for Cardiovascular Research Basel | Atrial Fibrillation, Cardiac Arrhythmia | 03/27 | 03/27 | | |
REDE-AF, NCT05817318: Renal Denervation in Patients With Recurrent Atrial Fibrillation After Successful Pulmonary Vein Isolation |
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| Recruiting | N/A | 40 | Europe | Renal Denervation | Insel Gruppe AG, University Hospital Bern, Medtronic | Arrhythmia Burden in Patients With Recurrent, Paroxysmal Atrial Fibrillation Despite Durable Pulmonary Vein Isolation | 06/26 | 12/26 | | |
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry |
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| Recruiting | N/A | 1000 | Europe, Canada, US, RoW | Defibrillation using EV-ICD | Medtronic | Ventricular Arrhythmia, Tachycardia | 05/30 | 10/37 | | |
| Beglinger, Christoph |
| Recruiting | N/A | 10000 | Europe, RoW | | Javier P. Gisbert | H. Pylori Infection | 12/34 | 12/34 | | |
NCT02902198: Taste Physiology in Obese Volunteers Before and After Bariatric Surgery |
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| Recruiting | N/A | 16 | Europe | Placebo, Glucose, Monosodium glutamate, Quinine | University Hospital, Basel, Switzerland | Obesity | 12/24 | 12/24 | | |
| Twerenbold, Raphael |
BASEL VIII, NCT01838148: Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia |
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| Recruiting | N/A | 4000 | Europe | | University Hospital, Basel, Switzerland | Coronary Artery Disease, Angina, Stable, Exercise Test, Biological Markers, SPECT | 12/22 | 12/24 | | |
| Recruiting | N/A | 10000 | Europe, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Myocardial Infarction, Angina, Unstable | 06/25 | 06/25 | | |
| Hochholzer, Willibald |
| Recruiting | N/A | 57 | Europe | Multimodality Imaging | Wuerzburg University Hospital | Myocardial Infarction, Myocardial Injury, Myocardial Inflammation | 12/25 | 12/26 | | |
| Katan, Mira |
DO-IT, NCT06571149: Safety and Efficacy of Intravenous Thrombolysis in Patients With Ischemic Stroke and Direct Oral Anticoagulants Intake |
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| Not yet recruiting | 4 | 906 | Europe, Canada, Japan, RoW | Tenecteplase or Alteplase | Insel Gruppe AG, University Hospital Bern | Ischemic Stroke | 01/29 | 04/29 | | |
MOSES, NCT03961334: MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention |
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| Recruiting | 3 | 620 | Europe | Dabigatran, Pradaxa, Apixaban, Eliquis, Edoxaban, Lixiana, Aspirin, Aspirin cardio, Clopidogrel | University of Zurich, Swiss National Science Foundation | Stroke, Ischemic | 01/25 | 01/26 | | |
NCT02274727: Biomarker Signature of Stroke Aetiology Study: The BIOSIGNAL-Study |
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| Active, not recruiting | N/A | 1800 | Europe | | University of Zurich, Swiss National Science Foundation | Stroke, Acute | 12/21 | 12/21 | | |
| Recruiting | N/A | 200 | Europe | | University Hospital, Basel, Switzerland, Swiss Academy of Medical Sciences (SAMS) | Acute Ischemic Stroke | 10/24 | 10/24 | | |
INVISIBLE-1, NCT06100718: Discovery of New Cancer in the 1-year Follow-up After Ischemic Stroke in Patients at Risk: The Study |
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| Recruiting | N/A | 370 | Europe | | Insel Gruppe AG, University Hospital Bern | Cancer-related Stroke, Paraneoplastic Coagulopathy, Occult Cancer, Ischemic Stroke, Embolic Stroke of Undetermined Source, D-dimer | 12/25 | 12/25 | | |
ELAPSE, NCT05976685: Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy |
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| Recruiting | N/A | 482 | Europe | Left atrial appendage Occlusion, DOAC | Insel Gruppe AG, University Hospital Bern | Ischemic Stroke, Atrial Fibrillation | 01/28 | 06/28 | | |
| Mayr, Michael |
EMPASTONE, NCT06653738: Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention |
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| Not yet recruiting | 3 | 380 | Europe | Empagliflozin 25 MG, Placebo, Personalized dietary counseling, Generic dietary counseling | Insel Gruppe AG, University Hospital Bern | Kidney Stone, Nephrolithiasis, Dietary Exposure | 02/30 | 06/30 | | |
RenalTWO, NCT05881447: Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa |
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| Recruiting | N/A | 1200 | RoW | | Swiss Tropical & Public Health Institute, University Hospital, Basel, Switzerland, Ifakara Health Institute | Chronic Kidney Diseases, Type 2 Diabetes Mellitus, Arterial Hypertension, Obesity, Cardiovascular Diseases, HIV Infections, Anemia, Underweight, Infections, Albuminuria, Dyslipidemias | 12/24 | 12/25 | | |
PROPHECY, NCT05542056: Urinary Prostaglandin as a Potential Predictive Marker for Thiazide-induced Hyponatremia |
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| Recruiting | N/A | 232 | Europe | Data and biosample collection | University Hospital, Basel, Switzerland | Thiazide-induced Hyponatremia (TIH) | 04/25 | 04/25 | | |
| Recruiting | N/A | 120 | Europe | Digital intervention (DiLCoS), Data collection | University Hospital, Basel, Switzerland, State Secretariat for Education Research and Innovation, Switzerland, European Union's Horizon Europe research and innovation programme | Post COVID-19 Condition (PCC) | 02/26 | 02/26 | | |
| Recruiting | N/A | 480 | Europe | Data collection for parameters of organ damage (cardiac and renal blood markers), Data collection for blood pressure (BP), Home-based blood pressure management (substudy), Biomarker Profiles (substudy), Data collection on patient reported outcomes | University Hospital, Basel, Switzerland | Postpartum Hypertension (PPHT) | 05/30 | 05/30 | | |
| Ruppen, Wilhelm |
| Completed | N/A | 76 | Europe | Open-Label Placebo, treatment as usual | University Hospital, Basel, Switzerland | Postoperative Pain | 01/23 | 01/23 | | |
NCT05906121: Lidocaine and Ketamine Levels in Plasma After Simultaneous Lidocaine/Ketamine Infusions |
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| Recruiting | N/A | 15 | Europe | lidocaine-ketamine infusions | University Hospital, Basel, Switzerland | Chronic Pain | 12/23 | 12/23 | | |
| Burri, Haran |
| Not yet recruiting | N/A | 50 | Europe | His bundle pacing, Right ventricular pacing | University Hospital, Geneva, Elise Bakelants, Carine Stettler, Rene NKoulou | Pacing-Induced Cardiomyopathy | 02/23 | 06/23 | | |
ABACUS, NCT06207383: Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure |
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| Recruiting | N/A | 220 | Europe | Conduction system pacing, Atrioventricular nodal ablation, Atrial fibrillation ablation | University Hospital, Geneva, Swiss National Science Foundation | Atrial Fibrillation, Persistent, Heart Failure | 06/28 | 12/28 | | |
NCT04496518: Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) |
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| Active, not recruiting | N/A | 2200 | Europe, US | Intrinsic Antitachycardia Pacing (iATP) Therapy | Medtronic | Ventricular Tachycardia | 01/25 | 01/27 | | |
NCT04489225: Personalized Therapy Study - HFRS (TriageHF) Post Approval Study |
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| Active, not recruiting | N/A | 2200 | Europe, US | Observational | Medtronic | Heart Failure | 01/25 | 01/27 | | |
| Recruiting | N/A | 470 | Europe, RoW | Left ventricular septal pacing, Right ventricular pacing | Maastricht University, ZonMw: The Netherlands Organisation for Health Research and Development, Medtronic | Cardiac Pacing, Pacing-Induced Cardiomyopathy, Conduction System Pacing, Left Ventricular Septal Pacing, Atrioventricular Block | 05/25 | 05/25 | | |
ASQ, NCT04024943: Personalized Therapy Study - Attain Stability Quad Post-Approval Study |
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| Active, not recruiting | N/A | 1092 | Europe, US | Quadripolar LV Lead, Medtronic CRT-P, Medtronic CRT-D | Medtronic | Heart Failure | 01/27 | 04/27 | | |
| Zanetti, Rosanna |
| Completed | N/A | 98 | Europe | Real-time elastography, Shear wave elastography | University Hospital, Basel, Switzerland | Breast Diseases | 12/21 | 12/23 | | |
| Reuthebuch, Oliver |
| Terminated | N/A | 2758 | Europe, Canada, US, RoW | | Corcym S.r.l | Aortic Valve Disease, Aortic Stenosis | 03/21 | 03/21 | | |
NCT04429256: Prosthetic Valve and Graft Endocarditis With Mycobacterium Chimaera |
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| Completed | N/A | 7 | Europe | data collection | University Hospital, Basel, Switzerland | Mycobacterium Chimaera Infections | 12/22 | 12/22 | | |
| Active, not recruiting | N/A | 200 | Europe, RoW | Tendyne™ Mitral Valve System, Transcatheter Mitral Valve Implantation (TMVI) | Abbott Medical Devices | Mitral Valve Regurgitation | 05/25 | 05/29 | | |
| Recruiting | N/A | 400 | Europe | Tendyne Mitral Valve System | Klinikum der Universitaet Muenchen | Mitral Regurgitation | 12/26 | 12/27 | | |
| Winzeler, Bettina |
| Recruiting | N/A | 78 | Europe | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Sexual Desire | 06/25 | 06/25 | | |
| Not yet recruiting | N/A | 600 | Europe | | University Hospital, Basel, Switzerland, University of Luzern | Transgender Individuals, Gender Incongruence | 01/45 | 01/45 | | |
| Bonati, Leo |
| Active, not recruiting | N/A | 3638 | Europe, Canada, Japan, US, RoW | CEA, CAS | University of Oxford, NHS Health Technology Assessment Programme, BUPA Foundation, British Heart Foundation | Carotid Stenosis | 12/20 | 12/25 | | |
NCT04805177: Early Minimally Invasive Image Guided Endoscopic Evacuation of Intracerebral Haemorrhage |
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| Completed | N/A | 11 | Europe | hematoma evacuation | University Hospital, Basel, Switzerland, Swiss Heart Foundation | Intracerebral Hemorrhage (ICH) | 12/23 | 07/24 | | |
| Marchis, Gian Marco De |
DO-IT, NCT06571149: Safety and Efficacy of Intravenous Thrombolysis in Patients With Ischemic Stroke and Direct Oral Anticoagulants Intake |
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| Not yet recruiting | 4 | 906 | Europe, Canada, Japan, RoW | Tenecteplase or Alteplase | Insel Gruppe AG, University Hospital Bern | Ischemic Stroke | 01/29 | 04/29 | | |
| Recruiting | 3 | 600 | Europe, US, RoW | Tenecteplase, Metalyse, Control | University Hospital of North Norway, UiT The Arctic University of Norway, The Royal Norwegian Ministry of Health, Norwegian Health Association | Ischemic Stroke, Stroke, Acute | 12/21 | 12/22 | | |
MOSES, NCT03961334: MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke Prevention |
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| Recruiting | 3 | 620 | Europe | Dabigatran, Pradaxa, Apixaban, Eliquis, Edoxaban, Lixiana, Aspirin, Aspirin cardio, Clopidogrel | University of Zurich, Swiss National Science Foundation | Stroke, Ischemic | 01/25 | 01/26 | | |
ELAN, NCT03148457: Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial |
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| Completed | N/A | 2013 | Europe, Japan, RoW | Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®) | Insel Gruppe AG, University Hospital Bern | Ischaemic Stroke | 12/22 | 05/23 | | |
DO-IT Cohort, NCT06556446: Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants |
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| Recruiting | N/A | 2800 | Europe, Canada, RoW | Tenecteplase and Alteplase | Insel Gruppe AG, University Hospital Bern, Swiss Stroke Trialist Association, Swiss Stroke Registry | Ischemic Stroke | 03/26 | 12/26 | | |
ELAPSE, NCT05976685: Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy |
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| Recruiting | N/A | 482 | Europe | Left atrial appendage Occlusion, DOAC | Insel Gruppe AG, University Hospital Bern | Ischemic Stroke, Atrial Fibrillation | 01/28 | 06/28 | | |
| Recruiting | N/A | 500 | Europe | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Ischemic Stroke | 12/25 | 12/25 | | |
| Bingisser, Roland |
SAFE-SSPE, NCT04263038: Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism |
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| Recruiting | 4 | 276 | Europe, Canada | Rivaroxaban, Placebo | Drahomir Aujesky, University of Bern, Schweizerischer Nationalfonds, Leiden University Medical Center, The Ottawa Hospital, Bayer | Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases, Cardiovascular Diseases, Respiratory Tract Diseases, Venous Thromboembolism, Anticoagulant-induced Bleeding, Bleeding | 05/26 | 05/26 | | |
NCT04351503: A Systems Approach to Predict the Outcome of SARS-CoV-2 in the Population of a City; COVID-19 |
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| Completed | N/A | 126586 | Europe | Study A, Study B, Study C, Study D | University Hospital, Basel, Switzerland, sciCORE University of Basel, Leonhard Med IT ETH Zurich, Swiss Institute of Bioinformatics | SARS Coronavirus (SARS-CoV-2) Infection | 07/22 | 07/22 | | |
| Completed | N/A | 6467 | Europe | Assessment of vital signs, Assessment of patient mobility at presentation, Assessment of level of consciousness by AVPUC scale, Assessment of symptoms patients presenting when admitted to ED, Assessment of what matters most in patients of 65 years and older, Assessment of Decision-making in senior physicians, Pain Numeric Rating Scale (NRS), Clinical Frailty Scale (CFS) | University Hospital, Basel, Switzerland | Triage Risk Stratification | 05/24 | 05/24 | | |
EPAC-II, NCT05156957: Effect of Physiotherapy in Patients Presenting to the Emergency Department With Nonspecific Lower Back Pain |
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| Completed | N/A | 126 | Europe | physiotherapeutic intervention | University Hospital, Basel, Switzerland | Lower Back Pain | 06/23 | 08/23 | | |
EPAC-I, NCT05156944: Effect of Physiotherapy in Patients Presenting to the Emergency Department After a Fall |
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| Completed | N/A | 104 | Europe | physiotherapeutic intervention | University Hospital, Basel, Switzerland | Fear of Falling | 06/23 | 08/23 | | |
| Recruiting | N/A | 1440 | Europe | The PLUS algorithm, Usual care | Dr Boillat-Blanco Noemie, Cantonal Hospital of St. Gallen, University Hospital, Basel, Switzerland, Kantonsspital Baden, Hôpital Intercantonal de la Broye, Payerne, Switzerland, Réseau Hospitalier Neuchâtelois, Switzerland, Hôpital Riviera-Chablais, Vaud-Valais, Luzerner Kantonsspital, Cantonal Hosptal, Baselland, St. Claraspital AG | Lower Respiratory Tract Infection | 03/25 | 05/25 | | |
| Kaiser, Christoph |
MATRIX-2, NCT05955365: Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation |
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| Recruiting | 4 | 3010 | Europe | P2Y12 inhibitor, Aspirin, DOAC | Insel Gruppe AG, University Hospital Bern, Sahajanand Medical Technologies Limited | Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF), Oral Anticoagulation, P2Y12 Inhibitor | 09/26 | 12/26 | | |
| Recruiting | N/A | 200 | Europe | continuous cardiac monitoring before and after transcatheter PFO closure | Raban Jeger | Cryptogenic Stroke, Foramen Ovale, Patent, Atrial Fibrillation | 05/27 | 05/27 | | |
| Reichlin, Tobias |
COMPARE-CRYO, NCT04704986: Comparison of PolarX and the Arctic Front Cryoballoons for PVI in Patients With Symptomatic Paroxysmal AF |
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| Active, not recruiting | 4 | 201 | Europe | PVI using the Arctic Front Cryoballoon (Medtronic), Arctic Front Cryoballoon, PVI using the PolarX Cryoballoon (Boston Scientific), PolarX Cryoballoon | Insel Gruppe AG, University Hospital Bern, University Hospital, Basel, Switzerland | Paroxysmal Atrial Fibrillation | 07/23 | 07/25 | | |
| Active, not recruiting | 4 | 210 | Europe | PVI using the Arctic Front Cryoballoon (Medtronic), PVI using FARAPULSE Pulsed Field Ablation (Boston Scientific) | Insel Gruppe AG, University Hospital Bern, University of Bern | Paroxysmal Atrial Fibrillation | 01/25 | 01/27 | | |
| Recruiting | 3 | 416 | Europe | Colchicine, Placebo | University Hospital, Basel, Switzerland, Swiss Heart Foundation, Fondation Machaon, Switzerland, Genf, Foundation for Cardiovascular Research Basel | Atrial Fibrillation, Cardiac Arrhythmia | 03/27 | 03/27 | | |
BASEL VIII, NCT01838148: Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia |
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| Recruiting | N/A | 4000 | Europe | | University Hospital, Basel, Switzerland | Coronary Artery Disease, Angina, Stable, Exercise Test, Biological Markers, SPECT | 12/22 | 12/24 | | |
| Completed | N/A | 119 | Europe | image-guided VT ablation strategy, conventional VT ablation strategy | University Hospital, Bordeaux, EIT Health | Ventricular Tachycardia | 12/23 | 12/24 | | |
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation |
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| Active, not recruiting | N/A | 669 | Europe, Canada, US | Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System | Boston Scientific Corporation | Persistent Atrial Fibrillation | 03/25 | 03/25 | | |
| Recruiting | N/A | 10000 | Europe, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Myocardial Infarction, Angina, Unstable | 06/25 | 06/25 | | |
| Recruiting | N/A | 200 | Europe | continuous cardiac monitoring before and after transcatheter PFO closure | Raban Jeger | Cryptogenic Stroke, Foramen Ovale, Patent, Atrial Fibrillation | 05/27 | 05/27 | | |
| Recruiting | N/A | 1000 | Europe, RoW | DiamondTemp™ Ablation System | Medtronic Cardiac Rhythm and Heart Failure | Arrhythmia | 03/31 | 03/31 | | |
| Gimenez, Maria Rubini |
| Recruiting | N/A | 10000 | Europe, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Myocardial Infarction, Angina, Unstable | 06/25 | 06/25 | | |
| Maushart, Claudia |
PULSAR, NCT04932135: Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of Hyperthyroidism |
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| Completed | N/A | 35 | Europe | Continuous heart rate monitoring, Regular measurements of thyroid hormone levels | University Hospital, Basel, Switzerland | Hyperthyroidism, Graves Disease | 03/23 | 10/23 | | |
| Nestelberger, Thomas |
NCT06472934: Impact of Beta-blocker on Outcome Among Patients Undergoing Transcatheter Aortic Valve Replacement (B-TAVR) |
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| Recruiting | N/A | 498 | Europe | Transcatheter aortic valve replacement in the absence of B-blocker treatment, Transcatheter aortic valve replacement | University Hospital, Basel, Switzerland | Aortic Stenosis | 05/28 | 05/28 | | |
| Completed | N/A | 50 | Europe | HemoSphere ClearSight Module | University of Basel | Aortic Valve Disease | 12/23 | 12/23 | | |
PROVE, NCT05539573: ACURATE neo2™ - Post Market Safety and Performance Surveillance in Aortic Stenosis |
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| Active, not recruiting | N/A | 1043 | Europe | Planned TAVI with the ACURATE neo2™ aortic bioprosthesis and ACURATE neo2™ transfemoral delivery system. | University of Leipzig, National University of Ireland, Galway | Aortic Stenosis | 04/25 | 04/25 | | |
| Recruiting | N/A | 150 | Europe, Canada, RoW | Elective redo transcatheter aortic valve implantation (redo-TAVI), redo-TAVI, redo-TAVR, Valve-in-Valve (ViV), TAV-in-TAV, TAVR-in-TAVR, Revalve | Institut für Pharmakologie und Präventive Medizin, Edwards Lifesciences | Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction, Prosthesis Failure | 09/25 | 12/26 | | |
| Boeddinghaus, Jasper |
| Recruiting | N/A | 10000 | Europe, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Myocardial Infarction, Angina, Unstable | 06/25 | 06/25 | | |
| Recruiting | N/A | 52156 | Europe, US, RoW | European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm, 0/1-hour algorithm, European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm, 0/3-hour algorithm | University Hospital, Basel, Switzerland | Acute Chest Pain, NSTEMI - Non-ST Segment Elevation MI | 09/24 | 09/25 | | |
| Köchlin, Luca |
| Recruiting | N/A | 10000 | Europe, RoW | | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Myocardial Infarction, Angina, Unstable | 06/25 | 06/25 | | |
| Escher, Robert |
SAFE-SSPE, NCT04263038: Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism |
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| Recruiting | 4 | 276 | Europe, Canada | Rivaroxaban, Placebo | Drahomir Aujesky, University of Bern, Schweizerischer Nationalfonds, Leiden University Medical Center, The Ottawa Hospital, Bayer | Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases, Cardiovascular Diseases, Respiratory Tract Diseases, Venous Thromboembolism, Anticoagulant-induced Bleeding, Bleeding | 05/26 | 05/26 | | |
EFFORT II, NCT04926597: Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery |
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| Recruiting | N/A | 802 | Europe | nutritional supplement, individualized nutritional guidelines, general nutritional information | Philipp Schuetz | Malnutrition | 08/24 | 12/24 | | |
| Recruiting | N/A | 1800 | Europe | Statin discontinuation, Intervention arm | Insel Gruppe AG, University Hospital Bern, University of Bern | Statin Treatment for Primary Prevention | 11/26 | 11/26 | | |
| Schwendinger, Markus |
| Recruiting | N/A | 1440 | Europe | The PLUS algorithm, Usual care | Dr Boillat-Blanco Noemie, Cantonal Hospital of St. Gallen, University Hospital, Basel, Switzerland, Kantonsspital Baden, Hôpital Intercantonal de la Broye, Payerne, Switzerland, Réseau Hospitalier Neuchâtelois, Switzerland, Hôpital Riviera-Chablais, Vaud-Valais, Luzerner Kantonsspital, Cantonal Hosptal, Baselland, St. Claraspital AG | Lower Respiratory Tract Infection | 03/25 | 05/25 | | |
| Kozbuharov, Nikola |
ABACUS, NCT06207383: Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure |
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| Recruiting | N/A | 220 | Europe | Conduction system pacing, Atrioventricular nodal ablation, Atrial fibrillation ablation | University Hospital, Geneva, Swiss National Science Foundation | Atrial Fibrillation, Persistent, Heart Failure | 06/28 | 12/28 | | |
| Mauler-Wittwer, Sarah |
| Recruiting | N/A | 150 | Europe, Canada, RoW | Elective redo transcatheter aortic valve implantation (redo-TAVI), redo-TAVI, redo-TAVR, Valve-in-Valve (ViV), TAV-in-TAV, TAVR-in-TAVR, Revalve | Institut für Pharmakologie und Präventive Medizin, Edwards Lifesciences | Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction, Prosthesis Failure | 09/25 | 12/26 | | |
