University Hospital Würzburg
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 49 Trials 
81 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Fassnacht, Martin
TOASST, NCT03153527: Taper Or Abrupt Steroid Stop: trial

Recruiting
4
573
Europe
Prednisone, Placebo Arm
University Hospital, Basel, Switzerland, Kantonsspital Baselland Bruderholz, Swiss National Science Foundation, HEMMI Stiftung Switzerland
Inflammatory Disorder, Autoimmune
12/26
12/26
CaboACC, NCT03612232: Cabozantinib in Advanced Adrenocortical Carcinoma

Active, not recruiting
2
37
Europe
Cabozantinib-s-malate
Wuerzburg University Hospital
Adrenocortical Carcinoma
12/24
04/25
Spencer, NCT04187404 / 2019-003396-19: A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma

Terminated
1/2
70
Europe, US
EO2401, Nivolumab
Enterome
Adrenocortical Carcinoma, Pheochromocytoma, Paraganglioma
05/24
10/24
NAPACAoutcome, NCT04917757: Clinical Outcome of Autonomous Cortisol Secretion in Adrenal Incidentalomas

Active, not recruiting
N/A
3656
Europe
1mg Dexamethasone test
Wuerzburg University Hospital, European Network for the Study of Adrenal Tumors
Adrenal Incidentaloma
08/19
12/24
CV-CORT-EX, NCT03880513: Cardiovascular Status in Patients With Endogenous Cortisol Excess (Cushing's Syndrome)

Completed
N/A
108
Europe
Cardiovascular status and quality of life
Wuerzburg University Hospital
Endogenous Cushing's Syndrome
10/22
10/22
ACHT, NCT04768127: Adipositas Care & Health Therapy

Active, not recruiting
N/A
586
Europe
early aftercare, mid-term to late aftercare
Wuerzburg University Hospital, Deutsche Stiftung für chronisch Kranke, Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie e.V. (DGAV), AOK Bayern, Kassenärztliche Vereinigung Bayern, symeda GmbH, AMC Wolfartklinik Gräfelfing, Schön Klinik Nürnberg Fürth, Dr. Lubos Kliniken Bogenhausen, Klinikum Memmingen, Klinikum Passau, Klinikum Nürnberg, Helmholtz Zentrum München
Patients After Metabolic-bariatric Surgery, Obesity, Morbid
11/22
12/24
NCT00457587: Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Recruiting
N/A
200
Europe
University of Wuerzburg, Deutsche Krebshilfe e.V., Bonn (Germany)
Adrenocortical Carcinoma, Cushing's Syndrome
12/25
12/26
NCT00568139: Evaluation of Side Effects of Mitotane

Active, not recruiting
N/A
400
Europe
University of Wuerzburg
Adrenocortical Carcinoma
12/24
12/25
NCT00669266: Adrenal Tumors - Pathogenesis and Therapy

Recruiting
N/A
500
Europe
University of Wuerzburg, Deutsche Krebshilfe e.V., Bonn (Germany), German Federal Ministry of Education and Research
Adrenal Tumors, Adrenocortical Carcinoma, Cushing Syndrome, Conn Syndrome, Pheochromocytoma
12/30
12/30
NCT00453674: German Adrenocortical Carcinoma Registry

Recruiting
N/A
1000
Europe
University of Wuerzburg, Deutsche Krebshilfe e.V., Bonn (Germany)
Adrenocortical Carcinoma
12/30
12/30
Einsele, Hermann
NCT01685814 / 2009-016616-21: Lenalidomide, Adriamycin, Dexamethasone (RAD) Versus Lenalidomide, Bortezomib, Dexamethasone (VRD) for Induction in Newly Diagnosed Multiple Myeloma Followed by Response-adapted Consolidation and Lenalidomide Maintenance

Active, not recruiting
3
406
Europe
Lenalidomide, Bortezomib, autologous stem cell transplant, allogeneic stem cell transplant
Wuerzburg University Hospital, ClinAssess GmbH, Celgene Corporation
Previously Untreated Symptomatic Multiple Myeloma
09/16
12/23
TRACE, NCT04832607 / 2018-000853-29: Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections

Recruiting
3
149
Europe
Multivirus (CMV, EBV, AdV)-specific T cells
Prof. Tobias Feuchtinger, European Commission, Simbec-Orion Group Ltd, Merthyr Tydfil, UK, Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany, Leiden University Medical Center, LUMC, Leiden, The Netherlands, Centre Hospitalier Universitaire de Nancy, CHU, Vandoeuvre-Lès-Nancy, France, Ghent University Hospital, UZG, Ghent, Belgium, Ospedale Pediatrico Bambino Gesù, OPBG, Rome, Italy, Newcastle University, UNEW, Newcastle, UK, Vall d'Hebron Institute of Oncology (VHIO) and Banc de Sang I Teixits (BST), Barcelona, Spain
AdV Infection, EBV Infection, CMV Infection, Stem Cell Transplant Complications
06/24
12/24
DSMM XVII, NCT03948035 / 2017-001616-11: Elotuzumab in Combination With Carfilzomib, Lenalidomide and Dexamethasone (E-KRd) Versus KRd in MM

Active, not recruiting
3
576
Europe
Elotuzumab, Empliciti®, Carfilzomib, Kyprolis®, Lenalidomide, Revlimid®, Dexamethasone, Fortecortin®, autologous stem cell transplant
Wuerzburg University Hospital, ClinAssess GmbH, Arbeitsgemeinschaft medikamentoese Tumortherapie
Newly Diagnosed Multiple Myeloma
08/29
08/29
EMN-COVID, NCT04492371: COVID-19 Infection and Multiple Myeloma

Completed
N/A
1054
Europe, RoW
Stichting European Myeloma Network, Fondazione EMN Italy Onlus
Multiple Myeloma, Covid19, Corona Virus Infection
08/22
03/24
MYRIAM, NCT03308474: Myeloma Registry Platform

Recruiting
N/A
2200
Europe
Routine care as per site standard.
iOMEDICO AG, Deutsche Studiengruppe Multiples Myelom (DSMM)
Multiple Myeloma
12/26
12/28
NCT03188874: Clinical AML Registry and Biomaterial Database of the Study Alliance Leukemia (SAL)

Recruiting
N/A
15000
Europe
Technische Universität Dresden
Acute Myeloid Leukemia (AML)
09/30
09/30
Meybohm, Patrick
IDA-II, NCT03817957: Postoperative i.v. Iron Substitution in Patients With Diagnosed Iron Deficiency

Recruiting
3
407
Europe
Polyglucoferron, Feramyl, Ferric carboxymaltose, Ferinject, Ferrous Sulfate, Ferro sanol duodenal
Dr. Frank Behrens, University Hospital Frankfurt, Department of Anaesthesiology, IRON4U, University Hospital Frankfurt Institute for Biostatistics & Mathematical Modelling
Iron Deficiency Anemia
12/22
12/22
VITDALIZE, NCT03188796 / 2016-002460-13: The Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients

Recruiting
3
2400
Europe
Cholecalciferol, Vitamin D3, Placebo
Medical University of Graz, Medical University of Vienna, Hospital Barmherzige Brüder St. Veit, Klinikum Klagenfurt am Wörthersee, Johannes Kepler University of Linz, Krankenhaus Barmherzige Schwestern Linz, Barmherzige Brüder Vienna, Erasme University Hospital, The Queen Elizabeth Hospital, Goethe University, Kages, KABEG Management, Centre Hospitalier Régional de la Citadelle, Centre Hospitalier Universitaire de Charleroi, Centre Hospitalier Universitaire Mons, Wuerzburg University Hospital, Royal Bolton Hospital NHS Foundation Trust, Heartlands Hospital, Royal Oldham Hospital, East Lancashire Hospitals NHS Trust, University of Plymouth, The Royal Victoria Hospital, Belfast, Great Western Hospital, Mid Yorkshire Teaching NHS Trust, Musgrove Park Hospital, Scunthorpe General Hospital, Guy's and St Thomas' NHS Foundation Trust, Nottingham University Hospitals, Hospital Barmherzige Brüder Graz, University Hospital Kiel, University Hospital, Bonn, Johannes Gutenberg University Mainz, University Hospital, Essen, Klinikum rechts der Isar der TUM, Landeskrankenhaus Villach
Critical Illness, Vitamin D Deficiency, Covid19
12/26
03/27
LIBERAL, NCT03369210: Liberal Transfusion Strategy in Elderly Patients

Recruiting
3
2470
Europe
red blood cell transfusion trigger
Johann Wolfgang Goethe University Hospital, Wuerzburg University Hospital
Transfusion-dependent Anemia, Surgery, Anemia
12/24
12/25
VICToRY, NCT04138394: VItamin C in Thermal injuRY: The Trial

Recruiting
3
666
Europe, Canada, US, RoW
Ascorbic Acid, vitamin C, placebo, saline, D5W
Clinical Evaluation Research Unit at Kingston General Hospital, Dr. Christian Stoppe, MD, Co-Principal Investigator, Wurzburg University, Wurzburg, Germany
Shock, Thermal Burn
12/26
06/27
EPOS-1, NCT05033808: Epirubicin for the Treatment of Sepsis & Septic Shock

Recruiting
2
45
Europe
Epirubicin, Placebo
Jena University Hospital, Ruhr University of Bochum, University Medicine Greifswald
Sepsis
10/24
12/24
ALICE, NCT03978260: Preoperative Anaemia prevaLence In surgiCal patiEnts

Completed
N/A
2500
Europe
Johann Wolfgang Goethe University Hospital, Medical University of Vienna, University Hospital, Angers, Medical University of Graz, Hospital del Mar, Hospital Hietzing, University of Zurich, Goethe University, Auckland City Hospital
Anemia, Iron-deficiency, Folic Acid Deficiency, Vitamin B 12 Deficiency, Anaemia of Renal Disease, Anemia of Chronic Inflammation
12/22
12/23
MONITOR, NCT05418881: Evaluation and Implementation of Mobile Tracking Devices to Increase Safety in Hospitalized Patients

Recruiting
N/A
500
Europe
Mobile Tracking Device (one spot), Mobile Tracking Device + Activity Sensor (longitudinal)
Wuerzburg University Hospital, University of Wuerzburg
Fitness Trackers, Hemodynamic Monitoring, Internet of Things, Postoperative Complications, Wearable Electronic Devices, Anesthesia, Surgery
10/23
11/23
KIPeriOP, NCT05284227: Artificial Intelligence-augmented Perioperative Clinical Decision Support

Recruiting
N/A
480
Europe
Electronic Clinical Decision Support Application, Standard procedures of the hospital and Sham Clinical Decision Support Application
Wuerzburg University Hospital, Goethe University, Charite University, Berlin, Germany, Asklepios Kliniken Hamburg GmbH, Fraunhofer Institute for Digital Medicine MEVIS, Technical University of Munich, RWTH Aachen University
ASA Class III/IV Patients, Surgery, Clinical Decision Support Systems
12/23
01/24
DigiSep, NCT04571801: Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics

Recruiting
N/A
410
Europe
Standard diagnostics, Next Generation Sequencing (NGS)
University Hospital, Essen, Noscendo GmbH, Germany, Health Economics and Health Care Management, Bielefeld University, Institute of Medical Biometry and Informatics, University of Heidelberg, Coordination Centre for Clinical Trials (KKS), University of Heidelberg, Department of Infectious Diseases, University Hospital Essen, Center for Infectious Diseases and Infection Control, Jena University Hospital, Department of Anesthesiology, Heidelberg University Hospital, AOK Health Insurance, Rheinland, Hamburg, Barmer Health Insurance, Germany, Techniker Health Insurance, Germany
Sepsis, Septic Shock
02/24
08/24
HYDRATE, NCT06253052: Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients

Completed
N/A
174
Europe
Additional pre-OP-visit, Liberal fasting regime
Wuerzburg University Hospital
Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
11/24
11/24
NCT02147795: The German Patient Blood Management Network

Recruiting
N/A
1000000
Europe
Johann Wolfgang Goethe University Hospital, Vifor Pharma, B. Braun Melsungen AG, CSL Behring, Fresenius Kabi
Clinical Safety of a PBM Program
12/24
12/25
Seefried, Lothar
BurGER, NCT04695860: Anti-FGF23 (Burosumab) in Adult Patients With XLH

Completed
3b
36
Europe
Burosumab
Wuerzburg University Hospital, Kyowa Kirin, Inc.
X-linked Hypophosphatemia
03/23
03/23
NCT05890794: Pilot Trial of Single Dose Ilofotase Alfa in Hypophosphatasia

Completed
1/2
12
Europe
Ilofotase Alfa, 0.8 mg/kg, recAP, Ilofotase Alfa, 3.2 mg/kg
AM-Pharma
Hypophosphatasia
07/23
07/23
IdeFIX, NCT04946409: Burden of Disease and Functional Impairment in XLH

Active, not recruiting
N/A
60
Europe
no intervention
Wuerzburg University Hospital, Kyowa Kirin, Inc.
X Linked Hypophosphatemia
03/24
10/24
Wanner, Christoph
RESOLVE, NCT02823821: Randomised Evaluation of Sodium Dialysate Levels on Vascular Events

Recruiting
4
50000
Europe, Canada, RoW
Default dialysate sodium concentration of 137mmol/l, Default dialysate sodium concentration of 140mmol/l
University of Sydney, Australasian Kidney Trials Network, Australia & New Zealand Dialysis & Transplant Registry, The George Institute for Global Health, India, The George Institute for Global Health, China, Peking University People's Hospital, Institute for Clinical Evaluative Sciences, St. Michaels Hospital, University Hospital Wuerzburg, Medizinische Klinik EINS, Malaysian Society of Nephrology, Malaysian Renal Registry, Comprehensive Clinical Trials Unit, University College London
End-Stage Kidney Disease
12/24
12/24
ALIGN, NCT04573478: Atrasentan in Patients With IgA Nephropathy

Active, not recruiting
3
404
Europe, Canada, Japan, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo
Chinook Therapeutics, Inc.
IgA Nephropathy, Immunoglobulin A Nephropathy
12/26
12/26
AD(H)PKD, NCT02497521: The German ADPKD Tolvaptan Treatment Registry

Recruiting
N/A
2000
Europe
University of Cologne
ADPKD (Autosomal Dominant Polycystic Kidney Disease)
11/25
12/27
Stoppe, Christian
SUSTAINCSX, NCT02002247: SodiUm SeleniTe Adminstration IN Cardiac Surgery (SUSTAIN CSX®-Trial).

Active, not recruiting
3
1400
Europe, Canada
sodium selenite, selenium, Placebo, NaCl 0.9%
Daren K. Heyland, biosyn Arzneimittel GmbH, Queen's University, RWTH Aachen University
Heart Disease
02/21
07/21
PROPER-LVAD, NCT04205760: Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device

Recruiting
3
40
Europe
Nutrition + exercise, bed cycling, ONS
RWTH Aachen University
Left Ventricular Assist Device, End-stage Heart Failure, Cardiac Surgery
07/23
12/23
LIBERAL, NCT03369210: Liberal Transfusion Strategy in Elderly Patients

Recruiting
3
2470
Europe
red blood cell transfusion trigger
Johann Wolfgang Goethe University Hospital, Wuerzburg University Hospital
Transfusion-dependent Anemia, Surgery, Anemia
12/24
12/25
VICToRY, NCT04138394: VItamin C in Thermal injuRY: The Trial

Recruiting
3
666
Europe, Canada, US, RoW
Ascorbic Acid, vitamin C, placebo, saline, D5W
Clinical Evaluation Research Unit at Kingston General Hospital, Dr. Christian Stoppe, MD, Co-Principal Investigator, Wurzburg University, Wurzburg, Germany
Shock, Thermal Burn
12/26
06/27
MODIFYCSX, NCT06279793: Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Recruiting
2
120
Europe
Long-chain n-3 fatty acids, Omegaven®, Intravenous 0.9% Sodium Chloride, Saline Infusion
GCP-Service International West GmbH, University Hospital, Bonn, University Hospital Muenster, University Hospital Goettingen, University Hospital Schleswig-Holstein, Charite University, Berlin, Germany, Wuerzburg University Hospital
Cardiac Surgery, High Risk Patients, Intensive Care Unit, Cardiopulmonary Bypass, Valve Surgeries
12/24
12/25
Biobank OIM, NCT03014427: Development of a Biological Database in the Field of Operative Intensive Care

Recruiting
N/A
99999999
Europe
Biological Database
RWTH Aachen University
Intensive Care in General
02/50
02/50
Jennes, Serge
NeupoNET, NCT02739295: G-CSF in the Treatment of Toxic Epidermal Necrolysis

Completed
4
10
Europe
recombinant granulocyte - colony stimulating factor, Neupogen (Amgen), NaCl 0.9%
University of Liege
Stevens - Johnson Syndrome
03/23
03/23
VICToRY, NCT04138394: VItamin C in Thermal injuRY: The Trial

Recruiting
3
666
Europe, Canada, US, RoW
Ascorbic Acid, vitamin C, placebo, saline, D5W
Clinical Evaluation Research Unit at Kingston General Hospital, Dr. Christian Stoppe, MD, Co-Principal Investigator, Wurzburg University, Wurzburg, Germany
Shock, Thermal Burn
12/26
06/27
Kranke, Peter
LIBERAL, NCT03369210: Liberal Transfusion Strategy in Elderly Patients

Recruiting
3
2470
Europe
red blood cell transfusion trigger
Johann Wolfgang Goethe University Hospital, Wuerzburg University Hospital
Transfusion-dependent Anemia, Surgery, Anemia
12/24
12/25
NCT05546359 / 2022-002947-23: Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients

Recruiting
2/3
410
Europe, Canada, US
Amisulpride Injection, Barhemsys, Dexamethasone, Decadron
Acacia Pharma Ltd, Amicus CD LLC, Premier Research Group plc
Nausea and Vomiting, Postoperative
06/25
12/25
NCT03567577 / 2017-003855-47: Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS

Recruiting
2
95
Europe
Solnatide 25 mg powder for reconstitution for solution for inhalation, AP301, 0.9% Saline Solution
Apeptico Forschung und Entwicklung GmbH
ARDS
12/24
12/24
EPOS-1, NCT05033808: Epirubicin for the Treatment of Sepsis & Septic Shock

Recruiting
2
45
Europe
Epirubicin, Placebo
Jena University Hospital, Ruhr University of Bochum, University Medicine Greifswald
Sepsis
10/24
12/24
Nordbeck, Peter
NCT04840667 / 2018-004689-32: A Study of Replagal in Treatment-naïve Adults With Fabry Disease

Terminated
3
17
Europe, Canada
REPLAGAL, SHP675
Shire
Fabry Disease
12/22
12/22
STAAR, NCT04046224 / 2019-000667-24: Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease

Active, not recruiting
1/2
34
Europe, Canada, US, RoW
ST-920
Sangamo Therapeutics
Fabry Disease
04/25
09/25
AIM-ICD, NCT04264455: Evaluation of Long-term Incidence of Ventricular Arrhythmias in Patients With Acute Myocarditis

Recruiting
N/A
34
Europe
Biomonitor, Life Vest, Implantable Cardioverter-Defibrillator (ICD)
Wuerzburg University Hospital, MVZ Leopoldina GmbH, Brandenburg Medical School Theodor Fontane, Hannover Medical School
Myocarditis Acute, Ventricular Arrythmia
12/22
12/23
NCT03022851: The Prophet Trial -Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients With Pulmonary Hypertension

Recruiting
N/A
30
Europe, RoW
Occlutech AFR Device
Occlutech International AB
Pulmonary Hypertension
02/23
12/23
DanShock, NCT01633502: Danish Cardiogenic Shock Trial

Completed
N/A
360
Europe
Conventional circulatory support, Conventional circulatory support will be employed according to enrolling sites usual management., Impella CP, Impella CP, Abiomed
Odense University Hospital, Aarhus University Hospital Skejby, Hannover Medical School, University Hospital, Bonn, Jena University Hospital, University Hospital Dresden, Heinrich-Heine University, Duesseldorf, Universitätsklinikum Hamburg-Eppendorf, Charite University, Berlin, Germany, Royal Brompton & Harefield NHS Foundation Trust, Wuerzburg University Hospital, Rigshospitalet, Denmark
Cardiogenic Shock Acute, Acute Myocardial Infarction
07/23
04/24
REDEAL-HF, NCT03966729: Relationships and Differences Analysis in Heart Failure

Recruiting
N/A
3000
Europe
Time (outcome)
Wuerzburg University Hospital
Heart Failure, Chronic Heart Failure, Chronic Heart Disease
12/23
12/23
MALTA-FABRY, NCT03683966: MigALastat Therapy Adherence Among FABRY Patients: A Prospective Multicentral Observational Study

Recruiting
N/A
30
Europe
Wuerzburg University Hospital, Charite University, Berlin, Germany, University Hospital Muenster, Health Care Center Dr. Markus Cybulla, Muellheim
Rare Diseases, Fabry Disease, Adherence, Medication, Quality of Life
12/23
12/23
NCT05425459: RESPONDER-HF Trial

Recruiting
N/A
750
Europe, Canada, US, RoW
Corvia Atrial Shunt System / IASD System II, Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)
Corvia Medical
Heart Failure, Heart Failure, Diastolic
05/25
03/31
PRAETORIAN-DFT, NCT03495297: A Randomised Trial of S-ICD Implantation with and Without Defibrillation Testing

Active, not recruiting
N/A
965
Europe, US
ommitence of defibrillation testing
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Boston Scientific Corporation
Ventricular Arrythmia
04/25
07/25
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Recruiting
N/A
1252
Europe, Canada, US
Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump
Abiomed Inc.
Left Ventricular Dysfunction, Coronary Artery Disease
03/26
10/27
GoPEG, NCT06095713: German Observational Multicenter Study of Patients With Fabry Disease Under Enzyme Replacement Therapy With Pegunigalsidase-alfa

Recruiting
N/A
60
Europe
Pegunigalsidase-alfa
Westfälische Wilhelms-Universität Münster, Chiesi GmbH
Fabry Disease
03/26
03/26
HEAL-FABRY, NCT03362164: Evaluation of HEArt invoLvement in Patients With FABRY Disease

Recruiting
N/A
650
Europe
Wuerzburg University Hospital, Competence Network Heart Failure, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), St George's, University of London
Rare Diseases, Fabry Disease, Fabry Disease, Cardiac Variant, Hypertrophic Cardiomyopathy
03/32
03/32
Bojunga, Jörg
TOASST, NCT03153527: Taper Or Abrupt Steroid Stop: trial

Recruiting
4
573
Europe
Prednisone, Placebo Arm
University Hospital, Basel, Switzerland, Kantonsspital Baselland Bruderholz, Swiss National Science Foundation, HEMMI Stiftung Switzerland
Inflammatory Disorder, Autoimmune
12/26
12/26
Wöckel, Achim
ADAPTcycle, NCT04055493: Adj. Marker-adjusted Personalized Therapy Comparing ET+Ribociclib vs Chemotherapy in Intermediate Risk, HR+/HER2- EBC

Active, not recruiting
3
1684
Europe
Ribociclib 200Mg Oral Tablet, Kisqali
West German Study Group, Novartis, Genomic Health®, Inc.
Breast Cancer Female
07/27
07/27
SMARAGD, NCT05129969: Registry Platform Ovarian and Endometrial Cancer

Recruiting
N/A
1375
Europe
Physician's choice according to patient's needs.
iOMEDICO AG
Ovarian Cancer, Endometrial Cancer, Ovary Neoplasm, Endometrial Neoplasms, Carcinoma, Ovarian, Carcinoma, Neoplasm, Ovarian
12/30
12/30
CATCH, NCT05652569: Implementation of Genomics-guided Precision Medicine in Metastatic Breast Cancer

Recruiting
N/A
5000
Europe
Genomic Profiling / Sequencing
German Cancer Research Center, University Hospital Heidelberg
Metastatic Breast Cancer
12/30
12/30
Polat, Bülent
NCT04246684: Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients

Active, not recruiting
3
702
Europe
Oxaliplatin, 85 mg/m2, Control arm, 5FU; 2400 mg/m2, 5-FU, control arm, 5FU, 250 mg/m2, Experimental arm: 5-FU, 5FU, 2400 mg/m2, experimental arm, Oxaliplatin 50 mg/m2, Experimental arm, Folinic Acid, 400 mg/m2, Folinic Acid, Radiotherapy control, 5x5 Gy: 25 Gy, Capecitabine, 1000 mg/m2, Capecitabine, Oxaliplatin 85 mg/m2, radiotherapy experimental, 30 x 1,8 Gy: 54 Gy, Capecitabine, 825 mg/m2, Oxaliplatin, 130 mg/m2, Oxaliplatin
Prof. Dr. med. Claus Rödel
Rectal Cancer Stage III
09/23
09/28
CAO/ARO/AIO-16, NCT03561142: Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy.

Recruiting
2
94
Europe
Radiotherapy, Chemotherapy, all brands of the used drugs are allowed, Deep regional hyperthermia
University Hospital Tuebingen
Rectal Cancer, Rectal Neoplasms, Rectal Cancer Stage II, Rectal Cancer Stage III
04/20
04/24
RADIANCE, NCT04230759 / 2018-003005-25: Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. a Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Active, not recruiting
2
180
Europe
Chemotherapy, all brands of 5-fluorouracil (5-FU) are allowed, all brands of Mitomycin C (MMC) are allowed, Radiation, Durvalumab, PD-L1 inhibitor
Goethe University, German Cancer Aid, AstraZeneca
Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage II
12/26
03/27
Razzouk, Louai
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Recruiting
N/A
1252
Europe, Canada, US
Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump
Abiomed Inc.
Left Ventricular Dysfunction, Coronary Artery Disease
03/26
10/27
Kroiss, Matthias
LIBRETTO-531, NCT04211337 / 2019-001978-28: A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer

Active, not recruiting
3
291
Europe, Canada, Japan, US, RoW
Selpercatinib, LY3527723, LOXO-292, Cabozantinib, Vandetanib
Loxo Oncology, Inc., Eli Lilly and Company
Medullary Thyroid Cancer
05/23
02/26
CaboACC, NCT03612232: Cabozantinib in Advanced Adrenocortical Carcinoma

Active, not recruiting
2
37
Europe
Cabozantinib-s-malate
Wuerzburg University Hospital
Adrenocortical Carcinoma
12/24
04/25
NCT03906331: Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation

Approved for marketing
N/A
Europe, Japan, US, RoW
Selpercatinib, LOXO-292, LY3527723
Eli Lilly and Company, Eli Lilly and Company
Non Small Cell Lung Cancer, Medullary Thyroid Cancer, Colon Cancer, Breast Cancer, Pancreatic Cancer, Papillary Thyroid Cancer, Other Solid Tumors With Evidence of Activating RET Alteration
 
 
Meraj, Perwaiz
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Recruiting
N/A
1252
Europe, Canada, US
Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump
Abiomed Inc.
Left Ventricular Dysfunction, Coronary Artery Disease
03/26
10/27
Kurotschka, Peter K
HEROES, NCT04352634: The Covid-19 HEalth caRe wOrkErS () Study

Recruiting
N/A
2000
Europe, US, RoW
Exposure to the SARS-CoV-2 and its consequences
University of Chile, Columbia University
Covid-19, Mental Health Disorder, Stress Disorder, Anxiety, Depression, SARS-CoV-2
12/21
12/21
CALIP, NCT04813731: COVID-19 and Lingering Symptoms in Primary Care Patients

Completed
N/A
300
Europe, RoW
Katarina Hedin, Research Unit for General Practice in Aalborg, Utrecht University, National University of Ireland, Galway, Ireland, Region Jönköping County
Covid19, Symptoms and Signs
06/22
06/22
MicUTI, NCT05667207: Dipsticks and Microscopy to Reduce Antibiotic Use in Women's Urinary Tract Infections: a Pilot Trial

Completed
N/A
154
Europe
Point-of-care microscopy and dipstick guided management
Wuerzburg University Hospital, University Hospital Erlangen, LMU Klinikum, University of Bristol, University of Santiago de Compostela, Università degli Studi di Trento, University of Wuerzburg, University of Georgia
Cystitis Acute, Antibiotic Resistant Infection, Medication Adherence, Urinary Tract Infection Bacterial, Urinary Tract Infection Lower Acute
04/24
04/24
NCT06625268: Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.

Recruiting
N/A
200
Europe
Wuerzburg University Hospital, Jena University Hospital
Urinary Tract Infection (Diagnosis)
01/25
01/25
Rodriguez, Crystal Ann
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
Nordbeck, PD Dr Peter
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
Buravezky, Larissa
DTU-STEMI, NCT03947619: Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: the STEMI-DTU Trial

Active, not recruiting
N/A
527
Europe, Canada, US
Impella CP® placement prior to reperfusion with Primary PCI
Abiomed Inc.
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
09/24
10/30
Chifu, Irina
TOASST, NCT03153527: Taper Or Abrupt Steroid Stop: trial

Recruiting
4
573
Europe
Prednisone, Placebo Arm
University Hospital, Basel, Switzerland, Kantonsspital Baselland Bruderholz, Swiss National Science Foundation, HEMMI Stiftung Switzerland
Inflammatory Disorder, Autoimmune
12/26
12/26
Punke, Mark
LIBERAL, NCT03369210: Liberal Transfusion Strategy in Elderly Patients

Recruiting
3
2470
Europe
red blood cell transfusion trigger
Johann Wolfgang Goethe University Hospital, Wuerzburg University Hospital
Transfusion-dependent Anemia, Surgery, Anemia
12/24
12/25
Kortüm
NCT06649695: A Phase II Trial of Teclistamab in Participants With Previously Treated Immunoglobulin Light-chain (AL) Amyloidosis

Not yet recruiting
2
30
Europe, RoW
Teclistamab, JNJ-64007957
European Myeloma Network B.V., Janssen Research & Development
AL Amyloidosis
09/28
09/28

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