Thoraxklinik
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 20 Trials 
31 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Kreuter, Michael
IMPALA-2, NCT04544293 / 2020-001263-85: Clinical Trial of Inhaled Molgramostim Nebulizer Solution in Autoimmune Pulmonary Alveolar Proteinosis (aPAP)

Active, not recruiting
3
160
Europe, Canada, Japan, US, RoW
Molgramostim, Recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF), Placebo
Savara Inc., Savara ApS,
Autoimmune Pulmonary Alveolar Proteinosis
11/23
11/24
BEconneCTD-ILD, NCT06572384: A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

Recruiting
3
440
Europe, Japan, US, RoW
Belimumab, BENLYSTA, GSK1550188, Placebo
GlaxoSmithKline
Lung Diseases, Interstitial
10/28
12/28
NCT05130970 / 2021-003162-12: Garadacimab Safety, Pharmacokinetics, and Pharmacodynamics in Idiopathic Pulmonary Fibrosis

Completed
2
81
Europe, Canada, US, RoW
Garadacimab, Factor XIIa antagonist monoclonal antibody, CSL312, Placebo
CSL Behring
Idiopathic Pulmonary Fibrosis
01/24
01/24
I-FILE, NCT04304898: An International Patient-led Registry in Fibrotic Interstitial Lung Diseases Using eHealth Technology

Recruiting
N/A
700
Europe
Home spirometry
Erasmus Medical Center
Pulmonary Fibrosis
07/25
07/26
ILDnose, NCT04680832: Exhaled Breath Analysis Using eNose Technology as a Biomarker for Diagnosis and Disease Progression in Fibrotic ILD

Recruiting
N/A
600
Europe
Electronic nose, SpiroNose, eNose
Erasmus Medical Center
Pulmonary Fibrosis
12/25
12/26
Herth, Felix JF
NIMBLE, NCT04718389 / 2020-003612-28: A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype

Hourglass Feb 2024 - Jun 2024 : Acceptance of regulatory submission in China for CRSwNP
Active, not recruiting
3
1667
Europe, Canada, Japan, US, RoW
GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS)
GlaxoSmithKline, Iqvia Pty Ltd
Asthma
10/25
10/25
RECOVER, NCT05200754: Trial With or Without Infusion of SARS-CoV-2 Antibody Containing Plasma in High-Risk Patients With COVID-19

Recruiting
2
174
Europe
Convalescent/Vaccine-boosted Plasma (CP/PVP)
Carsten Müller-Tidow, German Federal Ministry of Education and Research, Institut für Klinische Transfusionsmedizin und Zelltherapie Heidelberg gGmbH
SARS-CoV-2 Infection
04/22
06/22
NCT06317285: A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Recruiting
2
150
Europe, Canada, US, RoW
GSK3915393, Placebo
GlaxoSmithKline
Idiopathic Pulmonary Fibrosis
03/26
03/26
NCT03685526: Cinenses Lung Volume Reduction Reverser System First-in-man Study Treating Patients With Severe Emphysema

Active, not recruiting
N/A
15
Europe
Cinenses Lung Volume Reduction Reverser System
Lifetech Scientific (Shenzhen) Co., Ltd.
Emphysema
10/21
08/22
EFFORT, NCT04520152: Evaluation of the Free Flow Medical Lung Tensioning Device System for the Treatment of Severe Emphysema

Completed
N/A
14
Europe
FreeFlowMedical Lung Tensioning Device
University Medical Center Groningen
Emphysema or COPD
11/23
11/23
CONVERT, NCT04559464: Fissure Closure With the AeriSeal System for ing Collateral Ventilation Status

Completed
N/A
102
Europe, RoW
AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System
Pulmonx Corporation
Emphysema, COPD, Severe Emphysema
10/23
10/24
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema

Recruiting
N/A
200
Europe, US, RoW
AeriSeal System
Pulmonx Corporation
Emphysema, Pulmonary, Emphysema or COPD
06/27
03/28
IAB-1, NCT05087641: A Multicenter, Prospective Trial of the IAB in Adults Suffering From COPD/Emphysema

Active, not recruiting
N/A
20
Europe, RoW
IAB System
Pulmair Medical, Inc.
Emphysema, Pulmonary Disease, Chronic Obstructive
04/24
01/27
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

Active, not recruiting
N/A
270
Europe, US
RheOx Bronchial Rheoplasty, Sham Procedure
Gala Therapeutics, Inc.
Chronic Bronchitis
05/24
10/25
AIRFLOW-3, NCT03639051: Evaluation of the Safety and Efficacy of TLD in Patients with COPD

Active, not recruiting
N/A
464
Europe, US
Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care
Nuvaira, Inc.
COPD
10/24
09/28
NCT04182841: RheOx Registry Study in Europe

Recruiting
N/A
100
Europe
RheOx
Gala Therapeutics, Inc.
Chronic Bronchitis, COPD
12/24
12/25
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema

Recruiting
N/A
30
Europe
Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction
Morair Medtech, LLC
Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)
02/26
05/26
NCT03318406: Post-Market BTVA Registry

Recruiting
N/A
300
Europe
Bronchoscopic Thermal Vapor Ablation, BTVA, InterVapor
Uptake Medical Technology, Inc.
Emphysema or COPD
12/27
12/30
NCT05717192: BENTO - Bronchoscopic Lung Volume Reduction in Severe Emphysema Using Thermoablation

Recruiting
N/A
224
Europe
InterVapor®-System
IHF GmbH - Institut für Herzinfarktforschung
Emphysema or Chronic Obstructive Pulmonary Disease
04/26
12/27
Eberhardt, Ralf
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema

Recruiting
N/A
200
Europe, US, RoW
AeriSeal System
Pulmonx Corporation
Emphysema, Pulmonary, Emphysema or COPD
06/27
03/28
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema

Recruiting
N/A
30
Europe
Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction
Morair Medtech, LLC
Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)
02/26
05/26
NCT03318406: Post-Market BTVA Registry

Recruiting
N/A
300
Europe
Bronchoscopic Thermal Vapor Ablation, BTVA, InterVapor
Uptake Medical Technology, Inc.
Emphysema or COPD
12/27
12/30
NCT05717192: BENTO - Bronchoscopic Lung Volume Reduction in Severe Emphysema Using Thermoablation

Recruiting
N/A
224
Europe
InterVapor®-System
IHF GmbH - Institut für Herzinfarktforschung
Emphysema or Chronic Obstructive Pulmonary Disease
04/26
12/27
Gompelmann, Daniela
NCT04824495: Evaluation of Inflammatory Cytokines During COVID-19

Recruiting
N/A
100
Europe
Blood sample
University of Vienna
Covid19
08/21
12/21
NCT04827667: Impact of PD1-lymphocytes in Bronchoalveolar Lavage of Patients With Lung Cancer

Recruiting
N/A
40
Europe
bronchoalveolar lavage
University of Vienna
Lung Cancer
09/21
12/21
NCT03609541: Evaluation of Biomarkers of COPD Exacerbation

Recruiting
N/A
80
Europe
Heidelberg University
SAA Level and SAA/Lipoxin A4 Ratio
06/23
06/23
NCT06056882: Simultaneous CLE Guided Crybiopsy in Patients With Pulmonary Nodules

Recruiting
N/A
20
Europe
CLE-guided cryobiopsy
University of Vienna
Pulmonary Disease
03/24
06/24
NCT06655428: The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema

Recruiting
N/A
30
Europe
Endobronchial Therman Liquid Ablation (ETLA), Bronchoscopic lung volume reduction
Morair Medtech, LLC
Emphysema or COPD, Emphysema, Emphysema, Pulmonary, COPD, COPD (Chronic Obstructive Pulmonary Disease)
02/26
05/26
CLEVER, NCT06079970: Confocal Laser Endomicroscopy VERification

Recruiting
N/A
208
Europe, US, RoW
Neelde Based Confocal Laser Endomicroscopy, Conventional diagnostic bronchoscopy
Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC), Mauna Kea Technologies
Lung Cancer, Lung Neoplasm Malignant, Carcinoma, Non-Small-Cell Lung, Neoplasm of Lung
10/25
10/25
NCT04834830: Evaluation and Importance of the PD-1/PD-L1 and the IL-10/IL-10R Axis in Malignant and Benign Pleural Effusions - a Pilot Study

Recruiting
N/A
80
Europe
Pleural effusion will be examined for various cytokines and PD1-lymphocytes.
University of Vienna
Pleural Effusion
04/22
04/22
Ozturk-Sarioglu, Sevilay
CONVERT, NCT04559464: Fissure Closure With the AeriSeal System for ing Collateral Ventilation Status

Completed
N/A
102
Europe, RoW
AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System
Pulmonx Corporation
Emphysema, COPD, Severe Emphysema
10/23
10/24

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