University of Iowa Medical Center
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 8 Trials 
17 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Buatti, John M
NCT01752491: A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Completed
1
13
US
Ascorbate, Ascorbic Acid, Vitamin C, Temozolomide, Temodar, Radiation therapy, External beam radiation therapy
Joseph J. Cullen, MD, FACS, National Institutes of Health (NIH), National Cancer Institute (NCI)
Glioblastoma, GBM, Glioblastoma Multiforme
11/15
11/19
XACT-Fe-GBM-01, NCT04900792: A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma

Active, not recruiting
1
17
US
Ferumoxytol injection, Feraheme, Ferumoxytol, Pharmacological ascorbate, ASCOR, vitamin C, ascorbic acid, External beam radiation therapy, EBRT, radiotherapy, VMAT, Temozolomide, Temodar, temozolomide capsule
Bryan Allen, Holden Comprehensive Cancer Center, National Cancer Institute (NCI)
Glioblastoma, Glioblastoma Multiforme
06/25
12/26
Marsh, J Wallis
NCT01360606: Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Completed
N/A
9
US
Stereotactic Body Radiation Therapy, CyberKnife, Trilogy, True Beam, Radiosurgery
Susannah Ellsworth
Liver Metastases
07/18
02/21
NCT03809520: An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

Recruiting
N/A
20
US
pedCAT
J L Marsh, Orthopaedic Trauma Association
Orthopedic Disorder, Trauma, Ankle Fractures, Post-traumatic Osteoarthritis
12/24
12/24
PRMRP FPA CT, NCT05209347: Custom Dynamic Orthoses to Reduce Articular Contact Stress

Withdrawn
N/A
20
US
Carbon Fiber Custom Dynamic Orthosis (CDO), Ankle Foot Orthosis (AFO)
University of Iowa
Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
12/25
12/25
Cadaret, Linda
REBIRTH, NCT05180773: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting
4
250
US
Bromocriptine, Parlodel, Cycloset, Placebo, Guideline Directed Medical Therapy for Heart Failure (GDMT), Rivaroxaban, Xarelto, Second Placebo
Dennis M. McNamara, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)
Peripartum Cardiomyopathy, Postpartum
06/26
12/28
NCT03626688 / 2018-001187-33: A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Recruiting
3
1000
Europe, Canada, US, RoW
Ralinepag, APD811, Placebo
United Therapeutics
PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
12/25
12/25
IMPAHCT, NCT05036135 / 2021-001910-13: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Terminated
2/3
202
Europe, Canada, US, RoW
AV-101, Placebo
Aerovate Therapeutics, Aerovate Therapeutics, Inc.
Pulmonary Arterial Hypertension
08/24
08/24
PROACTIVE-HF, NCT04089059: IDE Trial Heart Failure NYHA Class III

Active, not recruiting
N/A
457
Europe, US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class III
04/28
04/28
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
PHAR, NCT04071327: Pulmonary Hypertension Association Registry

Recruiting
N/A
3000
US
Pulmonary Hypertension Association, Inc., University of Washington, the Collaborative Health Studies Coordinating Center
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
10/25
10/25
Larew, Cynthia
REBIRTH, NCT05180773: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting
4
250
US
Bromocriptine, Parlodel, Cycloset, Placebo, Guideline Directed Medical Therapy for Heart Failure (GDMT), Rivaroxaban, Xarelto, Second Placebo
Dennis M. McNamara, MD, MS, National Heart, Lung, and Blood Institute (NHLBI)
Peripartum Cardiomyopathy, Postpartum
06/26
12/28
GenePHIT, NCT05598333: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects with Non-Ischemic NYHA Class III Heart Failure

Recruiting
2
150
US
AB-1002, Gene Therapy, NAN-101
Asklepios Biopharmaceutical, Inc.
Congestive Heart Failure
10/26
12/30
PROACTIVE-HF, NCT04089059: IDE Trial Heart Failure NYHA Class III

Active, not recruiting
N/A
457
Europe, US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class III
04/28
04/28
Huffman, Amanda
PROACTIVE-HF, NCT04089059: IDE Trial Heart Failure NYHA Class III

Active, not recruiting
N/A
457
Europe, US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class III
04/28
04/28
AIM HIGHer, NCT05064709: Assessment of CCM in HF with Higher Ejection Fraction

Recruiting
N/A
1500
US
Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, CCM Group (CCM ON), OPTIMIZER™ Smart Mini System, Sham Group (CCM OFF)
Impulse Dynamics
Heart Failure, Heart Failure with Preserved Ejection Fraction, Heart Failure with Mid Range Ejection Fraction, Heart Failure with Moderately Reduced Ejection Fraction, Diastolic Heart Failure
02/25
02/26
NCT05934487: PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
N/A
1650
US
Cordella™ Pulmonary Artery Sensor System
Endotronix, Inc.
Heart Failure NYHA Class II, Heart Failure NYHA Class III
09/27
09/29

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