VA Portland Health Care System, Portland, OR
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 52 Trials 
145 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Lieberman, David
REVEAL, NCT05606614: Safety and Efficacy of TSHA-102 in Adolescent and Adult Females with Rett Syndrome ( Adult Study)

Recruiting
1/2
18
Canada, US
TSHA-102
Taysha Gene Therapies, Inc.
Rett Syndrome
01/25
01/32
NCT06152237: Safety and Efficacy of TSHA-102 in Pediatric Females with Rett Syndrome (REVEAL Pediatric Study)

Recruiting
1/2
20
Europe, Canada, US
TSHA-102
Taysha Gene Therapies, Inc.
Rett Syndrome
11/28
11/31
Emerald, NCT04514549: ASSESSING EMERALD AND MC10 BIOSTAMP nPOINT BIOSENSORS FOR RETT SYNDROME

Completed
N/A
21
US
Emerald, MC 10
Rett Syndrome Research Trust
Rett Syndrome
03/23
03/23
VIBRANT, NCT06338267: Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

Not yet recruiting
N/A
30
US
Rett Syndrome Research Trust
Rett Syndrome
12/25
12/25
NCT05932589: Neurophysiologic Biomarkers in Rett Syndrome

Recruiting
N/A
202
US
EEG and Auditory and Visual Evoked Potentials (AEP and VEP), Clinical assessment
Children's Hospital of Philadelphia, National Institute of Neurological Disorders and Stroke (NINDS), Vanderbilt University Medical Center
Rett Syndrome, RTT, Rett Syndrome, Atypical
03/28
03/29
Kelley, Michael J
ACHIEVE Study, NCT06096844: Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Recruiting
3
304
US
Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nab-paclitaxel, ABI 007, ABI-007, ABI007, Abraxane, Albumin-bound Paclitaxel, Albumin-Stabilized Nanoparticle Paclitaxel, Nanoparticle Albumin-bound Paclitaxel, Nanoparticle Paclitaxel, Naveruclif, Paclitaxel Albumin, paclitaxel albumin-stabilized nanoparticle formulation, Paclitaxel Nanoparticle Albumin-bound, Paclitaxel Protein-Bound, Protein-bound Paclitaxel, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
National Cancer Institute (NCI)
Advanced Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
06/26
06/26
S1914, NCT04214262: Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

Active, not recruiting
3
480
US
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Body Radiation Therapy, SABR, SBRT, Stereotactic Ablative Body Radiation Therapy
National Cancer Institute (NCI)
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8
05/28
05/28
EA5163, NCT03793179: Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Active, not recruiting
3
600
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT
National Cancer Institute (NCI)
Lung Non-Squamous Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
09/27
09/27
Lung-MAP Non-Match Sub-Study, NCT05096663: Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Checkmark Initiation of Lung-MAP trial in combination with Keytruda for 2L NSCLC
Apr 2022 - Apr 2022: Initiation of Lung-MAP trial in combination with Keytruda for 2L NSCLC
Active, not recruiting
2/3
82
US
Cobalamin, B12 Vitamin, Cobalamin (1+), VIT B12, Vitamin B-12, Vitamin B12, Vitamin-B12, Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycadron, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decadron DP, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasone Intensol, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Dxevo, Fluorodelta, Fortecortin, Gammacorten, Hemady, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, TaperDex, Visumetazone, ZoDex, Docetaxel, Docecad, RP56976, Taxotere, Taxotere Injection Concentrate, Folic Acid, 2-[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid, FA, Folacin, Pteroylmonoglutamic Acid, Vitamin B9, Vitamin Bc, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Nogapendekin Alfa, ALT 803, ALT-803, ALT803, Fusion Protein Consisting of IL-15N72D and IL-15RaSu/FC, IL-15N72D/IL-15Ra-Fc, IL-15N72D:IL-15RaSu/Fc Fusion Complex, N 803, N-803, N803, Superagonist Interleukin-15:Interleukin-15 Receptor AlphaSu/Fc Fusion Complex Alt-803, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Ramucirumab, Anti-VEGFR-2 Fully Human Monoclonal Antibody IMC-1121B, Cyramza, IMC-1121B, LY3009806, Monoclonal Antibody HGS-ETR2
SWOG Cancer Research Network, National Cancer Institute (NCI)
Advanced Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
02/27
12/27
Lung-Map Screening Study, NCT03851445: Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Recruiting
2/3
10000
US
Screening Platform
SWOG Cancer Research Network, National Cancer Institute (NCI)
Previously Treated Non-Small Cell Lung Cancer
01/29
01/29
RIVAL, NCT06275360: Repositioning Immunotherapy in VetArans With Lung Cancer

Recruiting
2
25
US
Nivolumab, Opdivo
VA Office of Research and Development
Non-Small Cell Lung Cancer
02/27
03/30
ECOG-ACRIN LUNG-MAP SUB-STUDY, NCT04625647: Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Active, not recruiting
2
116
US, RoW
Sotorasib, AMG 510, AMG-510, AMG510
SWOG Cancer Research Network, National Cancer Institute (NCI)
Lung Adenocarcinoma, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Squamous Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
12/26
12/27
NCT05563766: A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

Recruiting
2
78
US
Itraconazole
VA Office of Research and Development, Durham VA Health Care System, VA Palo Alto Health Care System, Portland VA Medical Center, VA Puget Sound Health Care System, Michael E. DeBakey VA Medical Center, VA Boston Healthcare System, North Texas Veterans Healthcare System, VA Ann Arbor Healthcare System
Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Gastroesophageal Junction Carcinoma
04/29
06/29
Chung, Kathryn Anne
STAT-PD, NCT04064294: Preventing Levodopa Induced Dyskinesia in Parkinson's Disease With HMG-CoA Reductase Inhibitors

Completed
N/A
75
US
Intravenous Infusion, levodopa
VA Office of Research and Development, Oregon Health and Science University
Parkinson Disease, Dyskinesia, Drug-Induced
03/24
03/24
Yadav, Vijayshree
MitoQ, NCT04267926: for Fatigue in Multiple Sclerosis (MS)

Active, not recruiting
1/2
47
US
20 mg MitoQ, Oral Mitoquinol, Placebo, 40mg of MitoQ
VA Office of Research and Development
Multiple Sclerosis, Fatigue
10/24
03/25
NCT03322982: Low Fat Diet for Fatigue in MS

Recruiting
N/A
108
US
Low-fat diet
Oregon Health and Science University, National Multiple Sclerosis Society
Multiple Sclerosis
09/21
03/22
PoNS TEP, NCT05437276: A Therapeutic Experience Program (TEP) Study for Improvement of Gait in People With Multiple Sclerosis (MS)

Recruiting
N/A
50
US
PoNS®
Helius Medical Inc
Gait Impairment Due to Mild/Moderate Multiple Sclerosis (MS)
12/23
07/24
MS-DETECT, NCT05816122: Early Detection of Multiple Sclerosis Progression with MSCopilot® Detect

Recruiting
N/A
314
Europe, Canada, US
MSCopilot® Detect mobile application
Ad scientiam
Multiple Sclerosis
12/26
12/26
Boudreau, Eilis
DREAM, NCT05419323: Direct Referral for Apnea Monitoring

Recruiting
N/A
2413
US
VA Office of Research and Development, San Francisco Veterans Affairs Medical Center
Obstructive Sleep Apnea (OSA)
09/25
09/25
Twamley, Elizabeth W
PACT, NCT04560946: Personalized, Augmented Cognitive Training () for Service Members and Veterans with a History of TBI

Completed
N/A
107
US
Personalized Augmented Cognitive Training (PACT), Enhanced Treatment As Usual
Veterans Medical Research Foundation, United States Naval Medical Center, San Diego
Traumatic Brain Injury
09/23
09/23
NCT03225482: Cognitive Rehabilitation Therapy for Mild Cognitive Impairment

Completed
N/A
193
US
Motivationally Enhanced Compensatory Cognitive Training, ME-CCT, Goal-focused Supportive Contact, SC
VA Office of Research and Development, Portland VA Medical Center
Mild Cognitive Impairment
06/24
06/24
NCT05985356: Neuromodulation for Comorbid Hoarding Disorder and Depression

Recruiting
N/A
12
US
iTBS, rTMS
University of California, San Diego
Hoarding Disorder, Hoarding, Depression
01/25
01/25
NCT05682677: Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

Recruiting
N/A
72
US
iTBS, sham iTBS, Personalized, Augmented Cognitive Training (PACT)
University of California, San Diego, San Diego Veterans Healthcare System
Depression, Mild Traumatic Brain Injury, Concussion, Brain
06/26
06/26
Spain, Rebecca
NCT03161028: Lipoic Acid for Progressive Multiple Sclerosis (MS)

Completed
2
115
Canada, US
Lipoic acid, Alpha-lipoic acid, Placebo
VA Office of Research and Development
Multiple Sclerosis
12/23
06/24
Graff, Julie
NCT04116775: Fecal Microbiota Transplant and Pembrolizumab for Men With Metastatic Castration Resistant Prostate Cancer.

Recruiting
2
32
US
Fecal microbiota transplant, FMT, Fecal transplant, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475, Enzalutamide, Xtandi, MDV3100, ASP9785
Julie Graff, MD, Merck Sharp & Dohme LLC, Prostate Cancer Foundation, Johns Hopkins University, Oregon Health and Science University
Prostate Cancer, Prostate Cancer Metastatic
10/23
10/23
NCT04267887: Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Active, not recruiting
2
7
US
Abiraterone Acetate, CB7630, Yonsa, Zytiga, Antiandrogen Therapy, ADT, Androgen Deprivation Therapy, Androgen Deprivation Therapy (ADT), Anti-androgen Therapy, Anti-androgen Treatment, Antiandrogen Treatment, Hormone Deprivation Therapy, Hormone-Deprivation Therapy, Apalutamide, ARN 509, ARN-509, ARN509, Erleada, JNJ 56021927, JNJ-56021927, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, Bone Scan, Bone Scintigraphy, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Questionnaire Administration
OHSU Knight Cancer Institute, Janssen Scientific Affairs, LLC, Oregon Health and Science University
Castration-Sensitive Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
01/28
01/30
NCT02312557: Pembrolizumab in Treating Patients With Metastatic Castration Resistant Prostate Cancer Previously Treated With Enzalutamide

Active, not recruiting
2
58
US
Enzalutamide, ASP9785, MDV3100, Xtandi, Laboratory Biomarker Analysis, Pembrolizumab, Keytruda, Lambrolizumab, MK-3475, SCH 900475
OHSU Knight Cancer Institute, Merck Sharp & Dohme LLC, Collins Medical Trust, Oregon Health and Science University
Castration-Resistant Prostate Carcinoma, Hormone-Resistant Prostate Cancer, PSA Progression, Recurrent Prostate Carcinoma, Stage IV Prostate Adenocarcinoma Cancer AJCC v8
06/24
06/24
BRACeD, NCT04038502: Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

Recruiting
2
100
US
Carboplatin, Paraplatin, Olaparib, Lynparza
VA Office of Research and Development
Metastatic Castrate Resistant Prostate Cancer, BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2, RAD51B, RAD51C, RAD51D, or RAD54L Mutations
08/25
08/25
CaRPET, NCT06610825: Castrate Resistant Prostate Cancer Enhertu Therapy

Not yet recruiting
2
60
NA
Enhertu
Washington D.C. Veterans Affairs Medical Center, Daiichi Sankyo, Cancer Research And Biostatistics, Institute for Clinical Research
Prostate Cancer Metastatic, Prostate Cancer, CRPC
10/27
10/28
VA-BAT, NCT05011383: High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

Recruiting
2
51
US
High dose testosterone, Bipolar androgen therapy
VA Office of Research and Development
Metastatic Prostate Cancer
08/26
08/27
Tamarack, NCT05551117: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

Hourglass Sep 2024 - Sep 2024 : Updated safety and efficacy data for mCRPC
Active, not recruiting
2
192
Europe, US, RoW
vobramitamab duocarmazine 2.0 mg (Arm A), MGC018, vobramitamab duocarmazine 2.7 mg (Arm B), vobramitamab duocarmazine, Abiraterone, Enzalutamide
MacroGenics
Castration-Resistant Prostatic Cancer, Androgen-Independent Prostatic Cancer, Androgen-Insensitive Prostatic Cancer, Androgen-Resistant Prostatic Cancer, Hormone Refractory Prostatic Cancer, Anal Cancer, Anal Neoplasm, Carcinoma, Squamous Cell of Head and Neck, Head and Neck Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Oral Squamous Cell Carcinoma, Malignant Melanoma, Melanoma, Non-small Cell Lung Cancer, Non-small Cell Carcinoma, Small-cell Lung Cancer, Small Cell Carcinoma
07/24
02/25
c15-148, NCT02522715: Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer

Active, not recruiting
1/2
37
US
Cabazitaxel, Jevtana, RPR-116258A, Taxoid XRP6258, XRP-6258, Enzalutamide, ASP9785, MDV3100, Xtandi, Laboratory Biomarker Analysis, Pharmacological Study, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, Perrigo Prednisone, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisone Intensol, Prednisonum, Prednitone, Promifen, Rayos, Servisone, SK-Prednisone
OHSU Knight Cancer Institute, Oregon Health and Science University
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer AJCC v7
10/19
01/25
NCT04706663: Precision-Based Genomics in Prostate Cancer

Recruiting
N/A
2000
US
National Cancer Institute (NCI)
Prostate Cancer
06/26
06/27
Lewis, M Samantha
NCT05740007: A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

Active, not recruiting
2
98
US
IW-3300 rectal foam, Placebo
Ironwood Pharmaceuticals, Inc.
Interstitial Cystitis, Bladder Pain Syndrome
01/25
02/25
Denneson, Lauren
NCT05199467: Health Coaching: A Pilot Trial Among Reintegrating Veterans

Active, not recruiting
N/A
95
US
Health Coaching, VA Benefits Information
VA Office of Research and Development, University of Michigan, VA Finger Lakes Healthcare System
Veteran Reintegration
03/25
03/25
NCT05484297: Increasing Social Connection Through Crisis Caring Contacts: A Pragmatic Trial

Recruiting
N/A
920
US
Crisis Caring Contacts post cards, Control post cards
VA Office of Research and Development
Loneliness
09/25
09/25
Hynes, Denise
CORC LTO, NCT05394025: COVID-19 Observational Research Collaboratory

Completed
N/A
731
US
VA Office of Research and Development, Johns Hopkins University
COVID-19, SARS-CoV-2 Infection
06/24
06/24
Pfeiffer, Paul N
NCT03536546: Improving Outcomes for Emergency Department Patients With Alcohol Problems

Completed
N/A
206
US
Alcohol Peer Mentor Intervention, APM, Brief Advice, BA
VA Office of Research and Development
Drinking, Alcohol
06/23
06/23
PREVAIL, NCT03373916: Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults

Completed
N/A
455
US
Peer mentorship, PREVAIL, Enhanced Usual Care
University of Michigan, National Institute of Mental Health (NIMH)
Suicidal Ideation
09/23
09/23
MIDAS SPCT, NCT06011759: Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth

Completed
N/A
4
US
Academic Detailing (AD), LEAP
VA Office of Research and Development
Suicidal Self-directed Violence, Suicidal Preparatory Behavior
08/24
08/24
SPARCS, NCT06656975: Social Prescribing and Relationship Cognitive Strategies

Enrolling by invitation
N/A
60
US
Brief Cognitive Therapy, Social Prescribing, Enhanced Usual Care
University of Michigan, National Institute of Mental Health (NIMH)
Social Isolation, Suicidal Ideation
07/26
07/26
MIDAS cRCT, NCT05065502: MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings

Completed
N/A
24
US
Academic Detailing (AD), LEAP
VA Office of Research and Development
Polypharmacy, Insomnia, Anticoagulants
03/24
05/24
NCT05484297: Increasing Social Connection Through Crisis Caring Contacts: A Pragmatic Trial

Recruiting
N/A
920
US
Crisis Caring Contacts post cards, Control post cards
VA Office of Research and Development
Loneliness
09/25
09/25
Morasco, Benjamin J
HOPE, NCT04571619: Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis

Completed
2
643
US
Pain Coping Skills Training (PCST), Buprenorphine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Hennepin Health Care, New York University, Massachusetts General Hospital, University of Illinois at Chicago, University of Pittsburgh, University of Washington, University of New Mexico, Rogosin Institute, Vanderbilt University Medical Center, West Virginia University, Yale University, Durham VA Health Care System, VA Portland Healthcare System, West Haven VA Medical Center, University of Pennsylvania, Dallas VA Medical Center, VA New York Harbor Healthcare System
End Stage Renal Disease, Chronic Pain, Opioid Dependence
12/23
05/24
CORPs, NCT06091202: Tele-Collaborative Outreach to Rural Patients With Chronic Pain

Active, not recruiting
N/A
608
US
CORPs Intervention, Nurse-led collaborative care, Minimally Enhanced Usual Care (MEUC), One-time Education Session
Oregon Health and Science University, National Center for Complementary and Integrative Health (NCCIH), Portland VA Medical Center, Minneapolis Veterans Affairs Medical Center, North Texas Veterans Healthcare System, VA Tennessee Valley Health Care System
Chronic Pain
06/27
09/27
wHOPE, NCT04330365: Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans

Recruiting
N/A
745
US
Whole Health Team (WHT) Intervention Arm, Primary Care Group Education (PC-GE) Intervention Arm, Usual Primary Care (UPC) Arm
San Francisco Veterans Affairs Medical Center
Chronic Pain
12/23
12/23
RAiSeD, NCT05530694: Rheumatoid Arthritis Shared Decision Making

Recruiting
N/A
792
US
Clinician communication training, fostering choice awareness, Patient activation, AskShareKnow, RA Medication summary guide and RA Choice
VA Office of Research and Development
Rheumatoid Arthritis
09/25
03/26
Klein, Robert F
NCT05978934: Determining How Indoor Lighting Affects the Brain Health of Older Adults

Recruiting
N/A
70
US
Static Lighting Condition (L1), Dynamic Lighting Condition (L2), Dynamic Lighting Condition (L3)
Well Living Lab, Inc., Mayo Clinic
Sleep, Physical Activity, Cognitive Function, Social Isolation
12/23
12/23
Hoffman, William F
MATAAR, NCT03973489: Effects of Genotype on Resting State Connectivity During Methamphetamine Administration

Completed
4
69
US
Magnetic resonance imaging (MRI), Methamphetamine Hydrochloride Tablets, Desoxyn, Placebo oral tablet
Oregon Health and Science University, Portland VA Medical Center
Methamphetamine-dependence
03/23
03/23
NAUD, NCT03338933: Neurobiology of Alcohol and Nicotine Co-Addiction

Completed
N/A
110
US
magnetic resonance imaging (MRI)
VA Office of Research and Development, Oregon Health and Science University
Alcohol Use Disorder, Nicotine Use Disorder
12/23
12/23
Stauffer, Christopher S
uAspire, NCT06308653: Psilocybin for Major Depressive Disorder (MDD)

Recruiting
3
240
US
Psilocybin 25 mg, Psilocybine, Psilocibin, Indocybin, Inactive Placebo, Microcrystalline Cellulose (MCC), Placebo, Psilocybin 5 mg, Psilocybine, Psilocibin, Indocybin, Active Comparator, Psychosocial Support
Usona Institute, Worldwide Clinical Trials
Depressive Disorder, Major
04/25
04/26
Bitting, Rhonda
VA STARPORT, NCT04787744: Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

Recruiting
2/3
464
US
PET-directed Local Therapy using Surgery, PET-directed Local Therapy using Radiation, Salvage Local Therapy for locally recurrent disease, Goserelin, Histrelin, Leuprolide & Triptorelin, ADT + Nilutamide, Flutamide, & Bicalutamide, Degarelix & Relugolix, ADT + Docetaxel +/- prednisone, ADT + Abiraterone + Prednisone, ADT + Abiraterone + Methylprednisolone, ADT + Apalutamide, ADT + Enzalutamide, Prostate-directed Radiation for De novo oligometastatic prostate cancer
VA Office of Research and Development
Prostate Cancer, Oligometastasis, Oligorecurrence, Recurrent Prostate Cancer, Metastatic Prostate Cancer, De Novo Prostate Cancer
07/25
12/25
CHOMP, NCT04104893: A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation

Recruiting
2
30
US
Pembrolizumab, Keytruda
VA Office of Research and Development, Merck Sharp & Dohme LLC
Metastatic Castration Resistant Prostate Cancer
03/25
12/25
BRACeD, NCT04038502: Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

Recruiting
2
100
US
Carboplatin, Paraplatin, Olaparib, Lynparza
VA Office of Research and Development
Metastatic Castrate Resistant Prostate Cancer, BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2, RAD51B, RAD51C, RAD51D, or RAD54L Mutations
08/25
08/25
CaRPET, NCT06610825: Castrate Resistant Prostate Cancer Enhertu Therapy

Not yet recruiting
2
60
NA
Enhertu
Washington D.C. Veterans Affairs Medical Center, Daiichi Sankyo, Cancer Research And Biostatistics, Institute for Clinical Research
Prostate Cancer Metastatic, Prostate Cancer, CRPC
10/27
10/28
VA-BAT, NCT05011383: High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

Recruiting
2
51
US
High dose testosterone, Bipolar androgen therapy
VA Office of Research and Development
Metastatic Prostate Cancer
08/26
08/27
IRONMAN, NCT03151629: International Registry for Men With Advanced Prostate Cancer

Recruiting
N/A
5000
Europe, Canada, US, RoW
Standard of Care
Prostate Cancer Clinical Trials Consortium
Prostate Cancer
01/31
01/32
Storzbach, Daniel M
CABA, NCT02391402: Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSD

Completed
N/A
73
US
Cognitively Augmented Behavioral Activation, CABA, Treatment as Usual, TAU
VA Office of Research and Development
Traumatic Brain Injury, Posttraumatic Stress Disorder
03/21
09/23
Pfeiffer, Christopher
diSArm, NCT05184764: Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia

Recruiting
1/2
50
US, RoW
AP-SA02, Placebo
Armata Pharmaceuticals, Inc., United States Department of Defense
Bacteremia, Staphylococcus Aureus, Staphylococcus Aureus Bacteremia, Bacteremia Staph, Bacteremia Due to Staphylococcus Aureus
12/24
03/25
GLORI, NCT04036058: Effect of Expanding (Gloving) Barrier Precautions for Reducing Clostridium Difficile Acquisition (and Infection) in VA

Active, not recruiting
N/A
10
US
Universal gloving, Expanded barrier precautions
VA Office of Research and Development, University of Wisconsin, Madison
Clostridium Difficile
12/23
09/24
Noelck, North
VA-IMPACT, NCT02915198 / 2018-000635-27: Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

Recruiting
4
7410
US
Metformin XR, Placebo
VA Office of Research and Development
Prediabetic State, Atherosclerosis, Metformin
03/29
03/29
Lobb, Brenna
CORT-PD, NCT02727270: Measuring Cortisol Levels in Persons With Parkinson's (PD)

Completed
N/A
131
US
No Intervention - Observational Study
Oregon Health and Science University, Portland VA Medical Center, Oregon Clinical and Translational Research Institute, Huntingtons Disease Society of America (HDSA)
Parkinson Disease, Huntington Disease
11/23
11/23
STAT-PD, NCT04064294: Preventing Levodopa Induced Dyskinesia in Parkinson's Disease With HMG-CoA Reductase Inhibitors

Completed
N/A
75
US
Intravenous Infusion, levodopa
VA Office of Research and Development, Oregon Health and Science University
Parkinson Disease, Dyskinesia, Drug-Induced
03/24
03/24
Tuepker, Anais
RAiSeD, NCT05530694: Rheumatoid Arthritis Shared Decision Making

Recruiting
N/A
792
US
Clinician communication training, fostering choice awareness, Patient activation, AskShareKnow, RA Medication summary guide and RA Choice
VA Office of Research and Development
Rheumatoid Arthritis
09/25
03/26
Pfeiffer, Chris
OpTION, NCT02667418: Optimal Treatment for Recurrent Clostridium Difficile

Completed
4
308
US
Fidaxomicin, Vancomycin with Taper/Pulse, Vancomycin
VA Office of Research and Development
Clostridium, Difficile, Fidaxomicin, Vancomycin
08/24
08/24
Waslo, Carin
PoNS TEP, NCT05437276: A Therapeutic Experience Program (TEP) Study for Improvement of Gait in People With Multiple Sclerosis (MS)

Recruiting
N/A
50
US
PoNS®
Helius Medical Inc
Gait Impairment Due to Mild/Moderate Multiple Sclerosis (MS)
12/23
07/24
Fiotto, Jade
BRAVO, NCT05931276: CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

Recruiting
3
2540
US
Metoprolol Succinate, Carvedilol
VA Office of Research and Development
End-Stage Kidney Disease, End-Stage Renal Disease
11/25
12/27
Kohno, Milky
NCT03341078: Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users

Recruiting
2
120
US
Ibudilast, Placebo Oral Tablet
VA Office of Research and Development, Portland VA Medical Center, Oregon Health and Science University
Methamphetamine-dependence
06/25
12/25
Lach, Laura
VA INTREPID, NCT03012529: Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics

Recruiting
4
880
US
Rifampin, Riboflavin Placebo
VA Office of Research and Development
Osteomyelitis, Diabetes, Amputation
09/25
09/25
Lim, Miranda M
BP1002-102-AML, NCT05190471: A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

Recruiting
1
48
US
BP1002; Liposomal Bcl-2 Antisense Oligodeoxynucleotide, Liposomal Bcl-2; L-Bcl-2, Decitabine (in combination with BP1002), Decitabine
Bio-Path Holdings, Inc.
Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
03/24
09/24
NCT03990909: Pilot Study of BCAA on Sleep

Recruiting
N/A
300
US
Branched Chain Amino Acids, BCAAs, Rice Protein, Microcrystalline Cellulose
Portland VA Medical Center
Sleep Disorder, Traumatic Brain Injury
08/24
08/25
NCT03968874: Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans

Recruiting
N/A
300
US
Light box therapy, Negative Ion Generator
Portland VA Medical Center, Center for Neuroscience and Regenerative Medicine (CNRM)
Traumatic Brain Injury
08/24
08/25
NCT03578003: Morning Bright Light to Improve Sleep Quality in Veterans

Recruiting
N/A
200
US
Morning Bright Light Therapy
Portland VA Medical Center, Oregon Health and Science University
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
08/24
08/26
SmART-TBI, NCT04603443: Supplementation With Amino Acid Rehabilitative Therapy in TBI

Recruiting
N/A
200
US
Branched Chain Amino Acids, BCAA-20, BCAA-40, BCAA-60, Protein Control
VA Office of Research and Development, Children's Hospital of Philadelphia, Oregon Health and Science University
Traumatic Brain Injury
09/25
09/25
NAPS2, NCT05826457: North American Prodromal Synucleinopathy Consortium Stage 2

Recruiting
N/A
500
Canada, US
Washington University School of Medicine, Mayo Clinic, University of Minnesota, University of California, Los Angeles, McGill University, Emory University, Massachusetts General Hospital, National Institute of Neurological Disorders and Stroke (NINDS), Stanford University, National Institutes of Health (NIH), Oregon Health and Science University, National Institute on Aging (NIA)
REM Sleep Behavior Disorder, Parkinson Disease, Lewy Body Dementia, Dementia With Lewy Bodies, Multiple System Atrophy, REM Sleep Parasomnias
05/25
05/25
O'Neil, Maya Elin
NCT03225482: Cognitive Rehabilitation Therapy for Mild Cognitive Impairment

Completed
N/A
193
US
Motivationally Enhanced Compensatory Cognitive Training, ME-CCT, Goal-focused Supportive Contact, SC
VA Office of Research and Development, Portland VA Medical Center
Mild Cognitive Impairment
06/24
06/24
NCT03696225: Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD

Active, not recruiting
N/A
21
US
Compensatory Cognitive Training (CCT), CCT, Treatment as Usual (TAU), TAU
VA Office of Research and Development
Posttraumatic Stress Disorder
09/24
12/25
NCT06728774: Cognitive Rehabilitation for Veterans with MDD-related Cognitive Functioning Deficits

Not yet recruiting
N/A
24
US
Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD), Compensatory Cognitive Training, Goal-focused Supportive Contact
Portland VA Medical Center, Oregon Health and Science University
Major Depressive Disorder (MDD), Cognitive Dysfunction
06/26
06/26
Bouwer, Archie Herman G
NCT03696225: Assessment and Treatment of Cognitive Functioning Deficits in Veterans With PTSD

Active, not recruiting
N/A
21
US
Compensatory Cognitive Training (CCT), CCT, Treatment as Usual (TAU), TAU
VA Office of Research and Development
Posttraumatic Stress Disorder
09/24
12/25
Koopman, Matthew
TOP, NCT03229941: Transfusion Trigger After Operations in High Cardiac Risk Patients

Completed
N/A
3012
US
Blood Transfusion
VA Office of Research and Development
Myocardial Infarction, Coronary Revascularization, Acute Renal Failure
06/23
03/24
Elliott, Jonathan E
NCT06182098: Intravenous Fluids in Pediatric Migraine

Recruiting
N/A
134
US
1/2 maintenance fluids, Normal saline, Ketorolac, Toradol, Diphenhydramine, Benadryl, Prochlorperazine, Compazine, bolus, normal saline
Dayton Children's Hospital
Migraine, Migraine in Children
06/25
06/25
SPTBI, NCT03785600: Improving Sleep in Veterans With TBI

Completed
N/A
100
US
Morning Bright Light Therapy, Lightbox, light therapy, Negative Ion Generator
VA Office of Research and Development
Traumatic Brain Injury
07/24
09/24
LIONv2, NCT06477796: Improving Sleep in Veterans With the Polytrauma Clinical Triad

Not yet recruiting
N/A
96
US
Morning Bright Light Therapy, Lightbox, light therapy, Negative Ion Generator
VA Office of Research and Development
Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
12/27
09/28
Jacky, Sharon D
SPTBI, NCT03785600: Improving Sleep in Veterans With TBI

Completed
N/A
100
US
Morning Bright Light Therapy, Lightbox, light therapy, Negative Ion Generator
VA Office of Research and Development
Traumatic Brain Injury
07/24
09/24
SmART-TBI, NCT04603443: Supplementation With Amino Acid Rehabilitative Therapy in TBI

Recruiting
N/A
200
US
Branched Chain Amino Acids, BCAA-20, BCAA-40, BCAA-60, Protein Control
VA Office of Research and Development, Children's Hospital of Philadelphia, Oregon Health and Science University
Traumatic Brain Injury
09/25
09/25
Theodoroff, Sarah
NCT05434637: Somatosensory Tinnitus RCT

Recruiting
N/A
72
US
Physical Therapy, Individualized Physiotherapy, Sound-based Therapy, Audiology Therapy, Combination Therapy, Physical Therapy + Audiology Therapy
VA Office of Research and Development
Tinnitus
06/26
09/26
Teo, Alan R
STEPS, NCT04597190: Sequenced Treatment Effectiveness for Posttraumatic Stress

Active, not recruiting
4
700
US
Selective serotonin reuptake inhibitor, Serotonin-norepinephrine reuptake inhibitor, Written Exposure Therapy
University of Washington, Stanford University, Boston University, Washington State University, Patient-Centered Outcomes Research Institute
PTSD
08/24
12/25
NCT05431166: Virtual Yoga for Social Isolation and Loneliness in Rural Veterans

Active, not recruiting
N/A
70
US
Virtual Yoga at First 8 weeks, Virtual Yoga at Second 8 weeks
Oregon Health and Science University
Loneliness, Social Isolation
09/23
09/23
NCT06470867: Randomized Controlled Effectiveness Trial of VA S.A.V.E.

Recruiting
N/A
710
US
VA S.A.V.E., Control training
VA Office of Research and Development
Suicide Prevention
05/27
03/28
NCT05484297: Increasing Social Connection Through Crisis Caring Contacts: A Pragmatic Trial

Recruiting
N/A
920
US
Crisis Caring Contacts post cards, Control post cards
VA Office of Research and Development
Loneliness
09/25
09/25
Shirley, Kate
CCT-A, NCT06134128: Compensatory Cognitive Training Via Telehealth for Veterans with Alcohol Use Disorders

Active, not recruiting
N/A
30
US
Motivationally Enhanced Compensatory Cognitive Training for Addictions Group
Portland VA Medical Center
Alcohol Use Disorder
06/25
06/25
NCT03902366: HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function

Completed
N/A
46
US
Neuropsychological assessment, Neuroimaging
VA Office of Research and Development, Oregon Health and Science University, Portland VA Medical Center
Hepatitis C, Alcohol Use Disorder
10/23
12/23
Loftis, Jennifer M
NCT03902366: HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function

Completed
N/A
46
US
Neuropsychological assessment, Neuroimaging
VA Office of Research and Development, Oregon Health and Science University, Portland VA Medical Center
Hepatitis C, Alcohol Use Disorder
10/23
12/23
Zaccari, Belle A
NCT05776719: Efficacy of Virtual Warrior Renew Therapy for Veterans Who Experienced Military Sexual Trauma

Recruiting
N/A
134
US
Health & Wellness, Warrior Renew
Seattle Institute for Biomedical and Clinical Research, United States Department of Defense
Military Sexual Trauma (MST), Post Traumatic Stress Disorder
11/26
01/30
Liu, Stephanie K
SCEPTER, NCT04142177 / 2013-003001-26: Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

Recruiting
N/A
2529
US
Pain EASE, Tailored exercise, Continued Care and Active Monitoring, Cognitive Behavioral Therapy (CBT), Spinal Manipulation Therapy (SMT), Yoga
VA Office of Research and Development
Chronic Low Back Pain
06/25
06/26
Finnell, John
SCEPTER, NCT04142177 / 2013-003001-26: Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

Recruiting
N/A
2529
US
Pain EASE, Tailored exercise, Continued Care and Active Monitoring, Cognitive Behavioral Therapy (CBT), Spinal Manipulation Therapy (SMT), Yoga
VA Office of Research and Development
Chronic Low Back Pain
06/25
06/26
Fryman, Allison
MitoQ, NCT04267926: for Fatigue in Multiple Sclerosis (MS)

Active, not recruiting
1/2
47
US
20 mg MitoQ, Oral Mitoquinol, Placebo, 40mg of MitoQ
VA Office of Research and Development
Multiple Sclerosis, Fatigue
10/24
03/25
Ioannou, George N
SACRED, NCT03654053: Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

Active, not recruiting
3
142
US
Placebo Oral Tablet, Placebo, Simvastatin 40mg, Simvastatin
VA Office of Research and Development
Cirrhosis
12/25
12/25
NCT05304234: Liver Cancer Disparities in American Indian and Alaska Native Persons

Recruiting
2
200
US
Ultrasound or abbreviated MRI
University of Washington, National Cancer Institute (NCI), Cherokee Nation Health Services, Alaska Native Tribal Health Consortium
Hepatocellular Carcinoma, Cirrhosis, Liver, Hepatitis B
09/25
09/26
COPE-VA, NCT06160128: COVID-19 Pharmacotherapy Effectiveness in the VA Healthcare System

Recruiting
N/A
400000
US
VA Office of Research and Development, Biomedical Advanced Research and Development Authority, Food and Drug Administration (FDA)
COVID-19, SARS-CoV-2 Infection, RSV, Influenza
09/25
09/27
 

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