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| Recruiting | 4 | 30 | Europe | Riociguat, MK-4836, ATC code: C02KX05 | Heidelberg University, Merck Sharp & Dohme LLC | Primary Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension | 03/26 | 03/26 | | |
CAPACITY, NCT04084678: A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH |
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| Terminated | 3 | 10 | Europe, Canada, US, RoW | Ralinepag, APD811, Placebo | United Therapeutics | PAH, Pulmonary Hypertension, Hypertension, Connective Tissue Disease, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease, Pulmonary Arterial Hypertension | 04/23 | 04/23 | | |
SOPHA, NCT04207593: The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With Hypoxemia |
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| Completed | 2 | 20 | Europe | Oxygen, Liquid oxygen | Heidelberg University | Oxygen Deficiency, Pulmonary Arterial Hypertension, CTEPH | 01/23 | 01/23 | | |
ESRA, NCT05339087: Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH |
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| Recruiting | 2 | 70 | Europe | Riociguat Oral Tablet, MK-4836, ATC Code: C02KX05, Placebo | Heidelberg University, Merck Sharp & Dohme LLC | Pulmonary Vascular Disorder, Primary Pulmonary Hypertension, Systemic Sclerosis, Other Systemic Involvement of Connective Tissue | 10/25 | 06/26 | | |
| Recruiting | N/A | 1500 | Europe, US, RoW | assessment of pulmonary hemodynamics during exercise by right heart catheterization | Medical University of Graz, European Respiratory Society | Pulmonary Circulation Diseases | 12/29 | 12/29 | | |
NCT04224012: Effect of Exercise and Respiratory Therapy on Right Ventricular Function in Severe Pulmonary Hypertension |
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| Recruiting | N/A | 96 | Europe | Exercise and respiratory therapy | Heidelberg University | Pulmonary Hypertension | 08/24 | 08/24 | | |
| Recruiting | N/A | 13000 | Europe | | Technische Universität Dresden, GWT-TUD GmbH | Pulmonary Arterial Hypertension (PAH), Pulmonary Hypertension (PH) | 06/26 | 06/26 | | |
NCT01387035: Early Diagnosis of Pulmonary Hypertension in Patients With Inflammatory Rheumatic Connective Tissue Diseases |
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| Recruiting | N/A | 50 | Europe | | Heidelberg University | Connective Tissue Disease, Pulmonary Hypertension | 12/25 | 12/25 | | |
| Recruiting | N/A | 250 | Europe | exercise and respiratory therapy | Heidelberg University | Pulmonary Hypertension | 12/25 | 12/25 | | |
| Not yet recruiting | N/A | 90 | Europe | Exercise rehabilitation, Standard treatment | Heidelberg University | Pulmonary Hypertension Due to Left Heart Disease, Heart Failure With Preserved Ejection Fraction | 12/25 | 12/26 | | |
