| Ellenbogen, Kenneth A |
REACT-AF, NCT05836987: The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation |
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| Recruiting | 3 | 5350 | US | AFSW Guided DOAC, Apple Watch, Continuous DOAC therapy, Oral Anticoagulation therapy | Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI) | Atrial Fibrillation | 07/29 | 07/29 | | |
FROZEN-AF, NCT04133168: Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation |
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| Completed | N/A | 458 | Europe, Canada, US, RoW | Boston Scientific Cardiac Cryoablation System | Boston Scientific Corporation | Paroxysmal Atrial Fibrillation | 11/22 | 08/23 | | |
CRT-DRIVE, NCT05327062: Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment |
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| Recruiting | N/A | 150 | Europe, US | CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment | XSpline S.p.A. | Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block | 03/25 | 09/25 | | |
| Active, not recruiting | N/A | 152 | Europe, US | ensoETM. Esophageal cooling during AF ablation, Esophageal temperature monitoring probe | Advanced Cooling Therapy, Inc., d/b/a Attune Medical, University of Pennsylvania, Berry Consultants, Texas Cardiac Arrhythmia Research Foundation, Beth Israel Deaconess Medical Center, Kansas City Cardiac Arrhythmia Research LLC | AF - Atrial Fibrillation, Complication, Atrio-Esophageal Fistula | 05/26 | 05/26 | | |
| Enrolling by invitation | N/A | 583 | US | | Boston Scientific Corporation | Paroxysmal Atrial Fibrillation | 07/25 | 10/25 | | |
| Completed | N/A | 90 | Europe, US | AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation, Irrigated Endocardial Catheters | AtriCure, Inc. | Atrial Fibrillation, Persistent or Longstanding Persistent Atrial Fibrillation | 03/22 | 04/24 | | |
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation |
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| Active, not recruiting | N/A | 669 | Europe, Canada, US | Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System | Boston Scientific Corporation | Persistent Atrial Fibrillation | 03/25 | 03/25 | | |
| Recruiting | N/A | 142 | Europe, US | AtriCure ISOLATOR Synergy Surgical Ablation System | AtriCure, Inc. | Inappropriate Sinus Tachycardia | 06/26 | 06/27 | | |
| Recruiting | N/A | 1500 | US | | Johns Hopkins University, University of Maryland, Baltimore, Medstar Health Research Institute, Virginia Commonwealth University, National Heart, Lung, and Blood Institute (NHLBI) | Heart Failure, Congestive, Death, Sudden, Cardiac, Arrhythmia, Cardiomyopathies | 03/28 | 03/29 | | |
| Active, not recruiting | N/A | 3000 | Europe, Canada, Japan, US, RoW | WATCHMAN FLX LAAC Device, WATCHMAN FLX Left Atrial Appendage Closure Device, Non-Vitamin K Oral Anticoagulant, NOAC | Boston Scientific Corporation | Atrial Fibrillation, Stroke, Bleeding | 12/27 | 12/27 | | |
| Recruiting | N/A | 2136 | US | His/LBBP, BiVP | Baylor College of Medicine, Patient-Centered Outcomes Research Institute, University of Utah, Virginia Commonwealth University, Rush University, East Carolina University | Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB, RBBB, Intraventricular Conduction Delay, Pacing-Induced Cardiomyopathy | 06/29 | 06/29 | | |
| Sterns, Laurence |
COBRRA AF, NCT04642430: COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation |
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| Recruiting | 4 | 3018 | Canada | Apixaban, Eliquis, Rivaroxaban, Xarelto | Ottawa Hospital Research Institute, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, Canadian Institutes of Health Research (CIHR) | Atrial Fibrillation | 12/26 | 12/26 | | |
| Active, not recruiting | 3 | 700 | Europe, Canada, US, RoW | Implantable Cardioverter Defibrillator + Usual Care, Implantable Cardioverter Defibrillator, ICD, Usual care, Standard medical therapy alone | University of Calgary, Canadian Institutes of Health Research (CIHR), Alberta Innovation and Science, Medtronic, GE Healthcare, Cardiac Arrhythmia Network of Canada, Accelerating Clinical Trials Consortium | Myocardial Infarction, Sudden Death | 12/24 | 12/24 | | |
| Active, not recruiting | N/A | 1686 | Europe, Canada, Japan, US, RoW | SyncAV programmed ON, Fixed AV delay | Abbott Medical Devices | Congestive Heart Failure | 06/25 | 12/25 | | |
| Chakrabarti, Shanta |
| Active, not recruiting | N/A | 1686 | Europe, Canada, Japan, US, RoW | SyncAV programmed ON, Fixed AV delay | Abbott Medical Devices | Congestive Heart Failure | 06/25 | 12/25 | | |
| Recruiting | N/A | 1500 | Canada, Japan | | Ottawa Heart Institute Research Corporation, Ontario Ministry of Health and Long Term Care, Canadian Institutes of Health Research (CIHR) | Cardiac Sarcoidosis | 12/25 | 12/25 | | |
| Sumner, Glen |
| Active, not recruiting | N/A | 1686 | Europe, Canada, Japan, US, RoW | SyncAV programmed ON, Fixed AV delay | Abbott Medical Devices | Congestive Heart Failure | 06/25 | 12/25 | | |
| Kar, Saibal |
| Active, not recruiting | N/A | 572 | Europe, Canada, US | TriClipTM Device | Abbott Medical Devices | Tricuspid Regurgitation | 11/22 | 04/29 | | |
NCT04029337: An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System |
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| Recruiting | N/A | 30 | US | Transcatheter Mitral Valve Replacement | HighLife SAS | Mitral Regurgitation | 12/24 | 12/27 | | |
| Recruiting | N/A | 250 | Europe, US | reSept ASD Occluder | atHeart Medical | Heart Septal Defect, Heart Septal Defects, Atrial, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases, Congenital Abnormalities | 12/26 | 12/30 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Enrolling by invitation | N/A | 1500 | US | Experimental: Laminar Left Atrial Appendage Closure System, Active Comparator: WATCHMAN / Amulet | Laminar, Inc., Cardiovascular Research Foundation, New York | Non-valvular Atrial Fibrillation, Stroke | 08/28 | 02/32 | | |
| Recruiting | N/A | 25 | US | CardioMech MVRS | CardioMech AS | Mitral Regurgitation | 12/25 | 12/30 | | |
| Recruiting | N/A | 380 | Canada, US | Arm 1: treatment with Neovasc Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry | Neovasc Inc., Shockwave Medical, Inc. | Refractory Angina | 06/25 | 12/28 | | |
NCT05565599: An Early Feasibility Study Evaluating the Safety and Efficacy of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation |
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| Active, not recruiting | N/A | 45 | US | Left Atrial Appendage Closure | Laminar, Inc. | Non-valvular Atrial Fibrillation | 08/24 | 09/29 | | |
NCT05913908: EFS of the DUO System for Tricuspid Regurgitation |
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| Recruiting | N/A | 15 | US | DUO Transcatheter Tricuspid Coaptation Valve System, DUO System | CroiValve Limited | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases | 12/25 | 10/29 | | |
NCT06212193: Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS) |
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| Recruiting | N/A | 15 | US | Trillium™ | Innoventric LTD, Innoventric Inc. | Tricuspid Regurgitation, Tricuspid Regurgitation Functional | 08/25 | 08/30 | | |
| Active, not recruiting | N/A | 949 | US | WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure | Boston Scientific Corporation | Atrial Fibrillation, Bleeding, Stroke | 07/24 | 08/25 | | |
| Recruiting | N/A | 1857 | US | WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device | Boston Scientific Corporation | Atrial Fibrillation, Stroke, Bleeding | 07/26 | 01/27 | | |
| Active, not recruiting | N/A | 102 | Europe, US | XIENCE Skypoint Large Vessel Everolimus Eluting Coronary Stent System (EECSS) | Abbott Medical Devices | Coronary Artery Disease | 08/25 | 08/27 | | |
| Recruiting | N/A | 15 | US | AltaValve | 4C Medical Technologies, Inc. | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence | 09/25 | 09/25 | | |
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion |
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| Active, not recruiting | N/A | 450 | Europe, Canada, US | Investigational PFO Closure Device, Standard of Care PFO Closure Device | Occlutech International AB | Stroke, Patent Foramen Ovale, PFO | 11/25 | 10/26 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Active, not recruiting | N/A | 3000 | Europe, Canada, Japan, US, RoW | WATCHMAN FLX LAAC Device, WATCHMAN FLX Left Atrial Appendage Closure Device, Non-Vitamin K Oral Anticoagulant, NOAC | Boston Scientific Corporation | Atrial Fibrillation, Stroke, Bleeding | 12/27 | 12/27 | | |
NCT00573027: Heart Disease of the Small Arteries in Women and Men |
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| Recruiting | N/A | 634 | US | noninvasive tests | Cedars-Sinai Medical Center | Heart Disease | 01/40 | 01/40 | | |
| Moront, Michael |
| Active, not recruiting | N/A | 1312 | Europe, Canada, US | Model 400 aortic valve bioprosthesis | Medtronic Cardiac Surgery, Medtronic | Aortic Stenosis | 04/23 | 12/35 | | |
| Recruiting | N/A | 150 | US | Penditure™ Left Atrial Appendage (LAA) Exclusion System | Medtronic Cardiac Surgery | Left Atrial Appendage Exclusion | 11/25 | 02/29 | | |
| Recruiting | N/A | 160 | US | Surgical Ablation, Cardioblate and Cryoflex hand held devices | Medtronic Cardiac Surgery | Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation | 10/24 | 12/26 | | |
| Recruiting | N/A | 150 | US | Medtronic Avalus Ultra | Medtronic Cardiac Surgery | Aortic Valve Disease | 11/26 | 11/26 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| RICHARDS, Mark |
NCT04792554: Singapore Perioperative Ageing Study (Sing-PAS) |
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| Recruiting | N/A | 600 | RoW | Neurocognitive tests and blood taking | National University Hospital, Singapore, National University, Singapore | Postoperative Delirium, Aging, Myocardial Injury | 12/25 | 12/26 | | |
SINGER, NCT05007353: The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty () Study |
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| Recruiting | N/A | 1200 | RoW | Structured Lifestyle Intervention, SLI, Self-Guided Intervention, SGI | National University, Singapore, National Medical Research Council (NMRC), Singapore | Cognitive Impairment, Alzheimer Disease, Vascular Cognitive Impairment, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Neurocognitive Disorders, Mental Disorders, Cognition Disorder | 12/25 | 01/26 | | |
| Doshi, Shephal |
| Completed | N/A | 117 | US | Patient Preference Survey | Abbott Medical Devices | Cardiac Rhythm Disorder, Bradycardia, Cardiac Pacemaker Artificial | 06/23 | 06/23 | | |
ULTRA-HFIB, NCT04182620: Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation |
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| Active, not recruiting | N/A | 160 | US | renal denervation, Catheter ablation | Vivek Reddy | Atrial Fibrillation | 03/25 | 03/25 | | |
RESOLVE-AF, NCT05883631: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy. |
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| Active, not recruiting | N/A | 400 | Europe, US, RoW | Electrographic Flow (EGF) mapping and ablation of EGF-identified sources of Atrial Fibrillation, OptiMap™ System, Electrographic Flow (EGF) mapping (no ablation) | Cortex, Ablacon, Inc. | Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrial Fibrillation Paroxysmal, Arrhythmia, Arrhythmias, Cardiac, Atrial Flutter, Atrial Fibrillation, Paroxysmal or Persistent, Atrial Arrhythmia, Atrial Tachycardia | 01/26 | 01/26 | | |
| Recruiting | N/A | 1600 | US, RoW | CLAAS, WATCHMAN left atrial appendage closure device / Amulet left atrial appendage occluder | Conformal Medical, Inc | Atrial Fibrillation, Stroke | 06/28 | 12/31 | | |
| Active, not recruiting | N/A | 3000 | Europe, Canada, Japan, US, RoW | WATCHMAN FLX LAAC Device, WATCHMAN FLX Left Atrial Appendage Closure Device, Non-Vitamin K Oral Anticoagulant, NOAC | Boston Scientific Corporation | Atrial Fibrillation, Stroke, Bleeding | 12/27 | 12/27 | | |
| Active, not recruiting | N/A | 300 | US | Renal Denervation | ReCor Medical, Inc. | Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases | 12/28 | 12/28 | | |
| Aasbo, Johan |
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy |
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| Recruiting | N/A | 620 | US | OPTIMIZER Smart System | Impulse Dynamics | Heart Failure | 03/26 | 03/26 | | |
| Recruiting | N/A | 500 | Europe, US | remede System | Respicardia, Inc. | Central Sleep Apnea | 06/27 | 06/32 | | |
| Abbas, Jihad |
NCT05633277: Outcomes of Sclerotherapy of the Ulcer Bed Compared to a Combination of Ablation and Injections |
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| Recruiting | N/A | 30 | US | Polidocanol, Radio Frequency Ablation, Endovenous Laser Ablation Therapy, Varithena, Venaseal, Sotradecol | ProMedica Health System, Jobst Vascular Institute | Venous Reflux, Venous Insufficiency, Venous Ulcer, Venous Disease | 09/23 | 03/24 | | |
C-TRACT, NCT03250247: Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The Trial) |
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| Recruiting | N/A | 250 | US | Stents | Washington University School of Medicine, Ontario Clinical Oncology Group (OCOG), Massachusetts General Hospital, Saint Luke's Mid America Heart Institute | Deep Vein Thrombosis, Venous Stasis, Venous Insufficiency, Venous Leg Ulcer, Venous Reflux, Post Thrombotic Syndrome | 01/26 | 04/26 | | |
NCT05907564: Aventus Thrombectomy System Pulmonary Embolism Clinical Study |
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| Recruiting | N/A | 120 | US | Thrombectomy | Inquis Medical, Inc. | Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases, Cardiovascular Diseases, Lung Diseases, Respiratory Tract Diseases | 03/25 | 03/25 | | |
| Leon, Marty |
| Active, not recruiting | N/A | 608 | Europe, Canada, Japan, US, RoW | IASD System II implant, intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE) | Corvia Medical | Heart Failure | 07/21 | 09/26 | | |
| Active, not recruiting | N/A | 3000 | Europe, Canada, Japan, US, RoW | WATCHMAN FLX LAAC Device, WATCHMAN FLX Left Atrial Appendage Closure Device, Non-Vitamin K Oral Anticoagulant, NOAC | Boston Scientific Corporation | Atrial Fibrillation, Stroke, Bleeding | 12/27 | 12/27 | | |
| Abu-Saif, Abeer |
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy |
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| Recruiting | N/A | 620 | US | OPTIMIZER Smart System | Impulse Dynamics | Heart Failure | 03/26 | 03/26 | | |
| Phelan, Timothy |
| Active, not recruiting | N/A | 1686 | Europe, Canada, Japan, US, RoW | SyncAV programmed ON, Fixed AV delay | Abbott Medical Devices | Congestive Heart Failure | 06/25 | 12/25 | | |
NCT03970343: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy |
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| Recruiting | N/A | 620 | US | OPTIMIZER Smart System | Impulse Dynamics | Heart Failure | 03/26 | 03/26 | | |
| Kenney, Lynn |
| No trials found |
| Ramanathan, Kasi |
| No trials found |
