Methodist Hospital
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 20 Trials 
39 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Carrum, George
NCT03870750: Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases

Recruiting
2/3
620
US
Supportive Palliative Care, Comfort Care, palliation, palliative care, palliative therapy, Palliative Treatment, Symptom Management, Symptoms Management, PA-Palliative Therapy, Clinical Management, Best Practice, standard of care, standard therapy, Allogeneic Hematopoietic Stem Cell Transplantation, Allogeneic Hematopoietic Cell Transplantation, Allogeneic Stem Cell Transplantation, HSC, HSCT, Stem Cell Transplantation, Questionnaire Administration, Quality-of-Life Assessment, Quality of Life Assessment, Survey Administration
Fred Hutchinson Cancer Center, National Cancer Institute (NCI), National Institutes of Health (NIH)
Hematopoietic and Lymphoid Cell Neoplasm, Non-Neoplastic Hematologic and Lymphocytic Disorder
06/25
06/25
ACCESS, NCT04904588: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Recruiting
2
300
US
Busulfan, Busulfex®, Fludarabine, Fludara®, Total-body irradiation, TBI, Cyclophosphamide, Cytoxan®, Melphalan, PBSC Hematopoietic Stem Cell Transplantation (HSCT), PBSC HSCT, PBSC HCT, PBSC Transplantation, Bone Marrow Hematopoietic Stem Cell Transplantation, BM HSCT, BM HCT, Bone Marrow Transplantation, Post-transplant Cyclophosphamide, Mesna, Mesnex®, Tacrolimus, Mycophenolate Mofetil, MMF, Cellcept®, Patient-Reported Outcomes
Center for International Blood and Marrow Transplant Research, National Marrow Donor Program
Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
07/24
07/24
BMTCTN1903, NCT04975698: HIV Antigen-specific T-cells Targeting Conserved Epitopes (HST-NEETs)

Recruiting
2
12
US
HST-NEETs, Bone Marrow Transplant
Catherine Bollard, National Heart, Lung, and Blood Institute (NHLBI), Blood and Marrow Transplant Clinical Trials Network, National Cancer Institute (NCI), National Marrow Donor Program, Children's National Research Institute
HIV Associated Lymphoma
06/25
06/26
TETRAVI, NCT04013802: Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

Recruiting
1
47
US
HLA-matched VSTs
Baylor College of Medicine, The Methodist Hospital Research Institute
Viral Infection
05/25
05/25
NCT03601442: CTL019 Out of Specification MAP for ALL or DLBCL Patients

Available
N/A
Canada, US, RoW
CTL019, tisagenlecleucel, Kymriah
Novartis Pharmaceuticals
Acute Lymphoblastic Leukemia (ALL), Diffuse Large B-cell Lymphoma (DLBCL)
 
 
HAPLOTAB, NCT05236764: Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Recruiting
N/A
47
US
CliniMACS
Baylor College of Medicine, Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital Research Institute
Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission, Myelodysplastic Syndromes, Chronic Myeloid Leukemia, Hemophagocytic Lymphohistiocytoses, Primary Immunodeficiency Diseases, Hemoglobinopathies, Severe Aplastic Anemia, Cytopenia, Bone Marrow Failure Syndrome, Severe Chronic Active Epstein-Barr Virus Infection
10/26
08/30
Gaber, Osama
ConfIdeS, NCT04935177: Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx

Recruiting
3
64
US
Imlifidase, IdeS, HMED-IdeS, PLEX, Plasma exchange, PE, IVIg, Intravenous immunoglobulin, Anti-CD20 antibodies, Rituximab, Eculizumab, Soliris, Remain on wait list
Hansa Biopharma AB
Kidney Transplantation in Highly Sensitized Patients
06/25
06/25
CPAT-ISR, NCT05077254: COVID Protection After Transplant-Immunosuppression Reduction

Active, not recruiting
2
400
US
Pfizer-BioNTech COVID-19 Vaccine 2023-2024, mRNA COVID-19 vaccine, BNT162b2 mRNA COVID-19 vaccine, SARS-CoV-2 RNA vaccine, Comirnaty, Moderna COVID-19 Vaccine 2023-2024, Moderna COVID-19 vaccine, SARS-CoV-2 vaccine, Spikevax, SOC IS Regimen, Standard of Care transplant immunosuppression regimen, Immunosuppression (IS), mycophenolate mofetil (MMF) or equivalent, tacrolimus, SOC IS Reduction, Standard of Care (SOC) transplant immunosuppression regimen, Immunosuppression (IS) Reduction
National Institute of Allergy and Infectious Diseases (NIAID), PPD, Johns Hopkins University
Kidney Transplant Recipients, Liver Transplant Recipients
02/24
03/25
ConfIdeSLTFU, NCT05714514: Survival and Dialysis Independency in Highly Sensitized Patients After Desensitization With Imlifidase and Tx of Kidneys

Recruiting
N/A
64
US
Imlifidase administered in the ConfIdeS study, IdeS, HMED-IdeS, Best available treatment administered in the ConfIdeS study
Hansa Biopharma AB
Kidney Transplantation in Highly Sensitized Patients
12/27
12/29
Kleiman, Neal S
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT05198674: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Recruiting
N/A
1400
Europe, US, RoW
Renal Denervation (Symplicity Spyral™), Renal Angiography, Renal Denervation
Medtronic Vascular
Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
11/26
11/29
TRICAV, NCT06137807: TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation

Not yet recruiting
N/A
15
US
TricValve® Transcatheter Bicaval Valve System, TricValve System
P+F Products + Features USA Inc., P+F Products + Features GmbH, Meditrial USA Inc.
Tricuspid Regurgitation, Tricuspid Valve Disease
11/25
11/29
NCT05149755: Evolut™ EXPAND TAVR II Pivotal Trial

Recruiting
N/A
650
Europe, Canada, Japan, US, RoW
Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT)
Medtronic Cardiovascular
Moderate Aortic Valve Stenosis
02/26
12/34
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
N/A
1056
Europe, Canada, US
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)
Medtronic Cardiovascular
Mitral Valve Regurgitation
10/26
09/36
Estep, Jerry
SEAL-IT, NCT04191681: Safety and Efficacy of ARNI After LVAD ImplanT () Study

Recruiting
4
50
US
Sacubitril-Valsartan, Entresto, Usual care (standard-of-care) arm, Oral Vasodilator
The Cleveland Clinic
Stage D Heart Failure
03/22
12/22
ALIVE-EA, NCT05710042: ALIVE Expended Access - Clinical Study

Available
N/A
US
Revivent TC System
BioVentrix
Heart Failure, Left Ventricle Remodeling
 
 
NCT02931240: BioVentrix Revivent TC™ System Clinical Study

Active, not recruiting
N/A
126
Europe, US, RoW
Revivent TC
BioVentrix
Ventricular Dysfunction, Left
12/23
06/27
Valderrabano, Miguel
REACT-AF, NCT05836987: The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Recruiting
3
5350
US
AFSW Guided DOAC, Apple Watch, Continuous DOAC therapy, Oral Anticoagulation therapy
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI)
Atrial Fibrillation
07/29
07/29
VELVET, NCT05511246: Venous Ethanol for Ventricular Tachycardia

Recruiting
2
156
US
Venous ethanol, Alcohol, Catheter ablation
The Methodist Hospital Research Institute
Ventricular Tachycardia, Ischemic Cardiomyopathy
12/27
12/28
TRAVERSE, NCT03946072: Transseptal vs Retrograde Aortic Ventricular Entry to Reduce Systemic Emboli

Completed
N/A
153
Canada, US
Transseptal Aortic Approach Catheter Ablation Procedure, Retrograde Aortic Approach Catheter Ablation Procedure
University of California, San Francisco
Neurocognitive Dysfunction
11/23
11/23
INTEGRA-D, NCT05855135: Assessment of Combined CCM and ICD Device in HFrEF

Recruiting
N/A
300
US
OPTIMIZER® Integra CCM-D System (Treatment Arm)
Impulse Dynamics
Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy, Non-ischemic Cardiomyopathy, Ischemic Cardiomyopathy, Sudden Cardiac Arrest, Arrhythmias, Cardiac, Ventricular Tachycardia, Ventricular Fibrillation
06/24
12/25
CATALYST, NCT04226547: Amplatzer Amulet LAAO vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
NCT03643224: DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation

Active, not recruiting
N/A
376
Europe, Canada, US, RoW
Radiofrequency Ablation
Medtronic Cardiac Rhythm and Heart Failure
Persistent Atrial Fibrillation, Atrial Fibrillation
10/24
12/24
Kew, Yvonne
NCT04373785: NG101m Adjuvant Therapy in Glioblastoma Patients

Not yet recruiting
2
52
US
Intensity-modulated radiation therapy, radiation therapy, Temozolomide, Temodar, NG101m, NG101m regimen
NeuGATE Theranostics
Glioblastoma Multiforme
07/27
12/27
Moore, Carolyn B
MOCHA, NCT03497676: More Options for Children and Adolescents (): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents

Active, not recruiting
1/2
168
US, RoW
Oral Cabotegravir (CAB), Oral Rilpivirine (RPV), Edurant, Long-Acting Injectable Cabotegravir (CAB LA), Long-Acting Injectable Rilpivirine (RPV LA), Combination Antiretroviral Therapy (cART)
National Institute of Allergy and Infectious Diseases (NIAID), ViiV Healthcare
HIV Infections
02/23
06/25
VMMC NEXUS, NCT06364891: Assessing the Impact of a Digital VMMC Platform

Recruiting
N/A
2000
RoW
VMMC NEXUS Digital application
University of Alabama at Birmingham, Centre for Infectious Disease Research in Zambia
Voluntary Medical Male Circumcision
12/24
12/24
Green, LaShawna
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT05061004: Cephea Early Feasibility Study

Recruiting
N/A
30
Canada, US
Cephea Mitral Valve System
Abbott Medical Devices
Mitral Regurgitation
06/24
06/29
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure With Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
06/24
12/30
Green, Lisa
NCT05411848: 2kcal Tube Feed Study

Completed
N/A
42
Europe
2kcal HP PlantBased
Nutricia UK Ltd
Enteral Nutrition, Cancer
12/23
12/23
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT05822557: Bolus Pouch Feed Study

Completed
N/A
30
Europe
Bolus Pouch Feed
Nutricia UK Ltd
Cancer, Neurological Disorder, Gastrointestinal Dysfunction, Oral Complication, Stroke
01/24
01/24
NCT03997305: AltaValve Early Feasibility Study Protocol

Recruiting
N/A
15
US
AltaValve
4C Medical Technologies, Inc.
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
09/25
09/25
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
Nieto, Krystin
GOAT, NCT06080698: Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

Recruiting
N/A
1204
US
Intravenous Antibiotics, Oral Antibiotics
Johns Hopkins University, Patient-Centered Outcomes Research Institute
Gram-negative Bacteremia
05/27
06/27
Banerjee, Joy
NCT00589017: Tamoxifen in Treating Patients With Metastatic Bladder Cancer That Did Not Respond to Previous Chemotherapy

Recruiting
2
75
US, Europe
tamoxifen citrate, immunohistochemistry staining method, laboratory biomarker analysis
Baylor College of Medicine
Bladder Cancer
07/10
 
Dinh, Tri A
VOCAL, NCT03837327: Clinical Validation of the InterVenn Ovarian CAncer Liquid Biopsy

Completed
N/A
1025
US, RoW
Venn Biosciences Corporation
Adnexal Mass, Ovarian Cancer, Pelvic Mass
01/24
01/24
Sun, David W
LAANTERN, NCT02392078: Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

Completed
N/A
1057
Canada, US
NeuroBlate System
Monteris Medical
Metastatic Brain Tumor, Primary Brain Tumor, Epileptic/Seizure Foci, Movement Disorders
09/23
09/23
Cheng, Charlie
TREO PAS, NCT04697784: Post-Approval Study of the TREO Abdominal Stent-Graft System

Recruiting
N/A
300
US
TREO Abdominal Stent-Graft System
Bolton Medical
Abdominal Aortic Aneurysm
07/27
07/27

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