The First Hospital of Hebei Medical University Trials

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Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Zhang, Wei

NCT04504864: Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds

Recruiting

400

RoW

low-dose aspirin, conventional-does aspirin

Xijing Hospital, Shaanxi Provincial People's Hospital, The First Affiliated Hospital of Jiaotong University, Tang-Du Hospital, The First Affiliated Hospital of Xi'an Medical University, Xi'an Central Hospital, Xiangyang Central Hospital, Baoji Central Hospital

Ischemic Stroke

02/22

08/22

PAIN-RELIEF, NCT04488315: Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-craniotomy Pain

Active, not recruiting

130

RoW

Dexamethasone lipid microsphere plus ropivacaine, ropivacaine plus D-PAL, Ropivacaine alone

Beijing Tiantan Hospital

Pain, Postoperative

09/23

12/23

ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis

Recruiting

364

RoW

Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline

Shanghai Pulmonary Hospital, Shanghai, China

Bronchiectasis Adult, Pseudomonas Aeruginosa Infection

10/25

12/25

NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease

Recruiting

1312

RoW

GV-971, Placebo

Green Valley (Shanghai) Pharmaceuticals Co., Ltd.

Alzheimer's Disease

06/29

12/29

NCT04504396: Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy

Completed

620

RoW

GLP-1 receptor agonist, Placebo, PB-119 Placebo

PegBio Co., Ltd.

Type 2 Diabetes Mellitus (T2DM)

09/22

05/23

NCT04683406: A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A

Completed

750

RoW

ZSP1273 600 mg, Placebo to Oseltamivir, Oseltamivir(oral), Placebo to ZSP1273

Guangdong Raynovent Biotech Co., Ltd

Influenza A

04/23

05/23

NCT06103825: A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients With Obstructive Sleep Apnea (OSA)

Recruiting

204

RoW

Solriamfetol, Placebo

Ignis Therapeutics (Suzhou) Limited

Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea

09/24

10/24

TRAILRUNNER-ALZ 3, NCT06653153: A Study of Remternetug (LY3372993) in Early Alzheimer's Disease

Recruiting

1200

Europe, Canada, Japan, US, RoW

Remternetug, LY3372993, Placebo

Eli Lilly and Company

Alzheimer's Disease

04/29

10/30

TRAILBLAZER-ALZ 5, NCT05508789: A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease

Recruiting

1500

Europe, RoW

Donanemab, (LY3002813), Placebo

Eli Lilly and Company

Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders

04/27

NCT05215379: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer

Recruiting

2/3

180

RoW

xintilimab injection, Control

Changhai Hospital

Neoadjuvant Chemoradiation Therapy, Rectal Cancer, Immunotherapy, Microsatellite Instability Low

10/24

04/25

NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease

Recruiting

RoW

50561 high dose, 50561 low dose, Placebo

Beijing Joekai Biotechnology LLC

Alzheimer's Disease

05/24

06/24

NCT03746223: Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal Lymphoma

Recruiting

RoW

Methotrexate, Rituximab, Lenalidomide

Peking Union Medical College Hospital

Primary Intraocular Lymphoma

11/20

10/25

NCT05229029: RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy

Active, not recruiting

196

RoW

TCM Formula, RSYR decoction, Placebo, Placebo dicoction

Peking University Cancer Hospital & Institute

Cancer-related Problem/Condition

09/23

06/24

NCT04899427: Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma

Recruiting

RoW

orelabrutinib, Sintilimab, Tislelizumab

Peking Union Medical College Hospital, Beijing Hospital, Beijing Tongren Hospital, Beijing Luhe Hospital, Shanxi Province Renmin Hospital, Henan Cancer Hospital, Henan Province Renmin Hospital, The Second Affiliated Hospital of Dalian Medical University, The Forth Hospital of Hebei Medical University, The First Hospital of Chinese Medical University, Qilu Hospital of Shandong University, The First Hospital of Zhengzhou University

Primary Central Nervous System Lymphoma

03/23

10/23

NCT06259526: A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression

Recruiting

260

RoW

Placebo group, JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 low-dose group, JS1-1-01 pills; JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 pills; JS1-1-01 placebo pills, JS1-1-01 high-dose group, JS1-1-01 pills; Duloxetine hydrochloride placebo capsules, Active drug group, JS1-1-01 placebo pills; Duloxetine hydrochloride enteric coated capsule

Tasly Pharmaceutical Group Co., Ltd

Depression

04/25

NCT05179213: Azacytidine Plus Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma

Not yet recruiting

RoW

Azacitidine, Chidamide

Peking Union Medical College Hospital, Beijing Longfu Hospital

Angioimmunoblastic T-cell Lymphoma

01/24

05/24

NCT06093841: Relmacabtagene Autoleucel as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL

Not yet recruiting

RoW

Relmacabtagene Autoleucel, JWCAR029, Fludarabine, Cyclophosphamide

Shanghai Ming Ju Biotechnology Co., Ltd.

Lymphoma, Large B-Cell, Diffuse, Follicular Lymphoma Grade 3B, High-grade B-cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell Lymphoma

08/24

02/27

NCT05555901: The Efficacy and Safety of Fruquintinib Plus Chemotherapy as Second-line Treatment in Metastatic Colorectal Cancer

Recruiting

116

RoW

Fruquintinib+ chemotherapy, Bevacizumab+ chemotherapy

Fudan University

Metastatic Colorectal Cancer

09/25

NCT02987244: Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell Lymphoma

Recruiting

1/2

100

RoW

Chidamide, epidaza, Cyclophosphamide, Epirubicin, Vindesine, Etoposide, Prednisone

Peking Union Medical College Hospital, Chinese PLA General Hospital, Peking University First Hospital, Peking University Third Hospital, Peking University Cancer Hospital & Institute, Tianjin Medical University Cancer Institute and Hospital

T Cell Non-Hodgkin's Lymphoma

03/20

03/23

GLORY, NCT04270591: Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer

Recruiting

1/2

183

Japan, US, RoW

Glumetinib, SCC244

Haihe Biopharma Co., Ltd.

C-Met Exon 14 Mutation

10/23

12/23

NCT05464433: Tislelizumab Combined With Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma

Recruiting

1/2

RoW

Tislelizumab combined with Liposomal mitoxantrone hydrochloride, Maintenance of tislelizumab

Sun Yat-sen University

Extranodal Natural Killer T Cell Lymphoma

01/24

01/25

NCT05370547: Chidamide Bridging for CAR-T Therapy

Recruiting

1/2

120

RoW

Chidamide, HDACi, Fludarabine and cyclophosphamide, FC regimen, Anti-CD19 CAR-T cells, Relma-cel, Axi-cel, Other commercial CAR-T cells, Experimental CAR-T cells

Chinese PLA General Hospital

Non Hodgkin's Lymphoma

06/24

06/25

NCT06393413: To Explore the Therapeutic Potential of Jiedu Yizhi Formula for Alzheimer 's Disease

Completed

RoW

Jiedu Yizhi Formula, Donepezil Hydrochloride Tablets

Changchun University of Chinese Medicine

Ensure the Legality and Compliance of the Testing Process

12/23

04/24

NCT05240950: Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases

Recruiting

RoW

Anti-CEA CAR-T Cells

Changhai Hospital

Colorectal Cancer, Metastatic Liver Cancer

12/23

12/26

NCT05577091: Tris-CAR-T Cell Therapy for Recurrent Glioblastoma

Recruiting

RoW

Inverse correlated dual-target, truncated IL7Ra modified CAR -expressing autologous T-lymphocytes., Autologous Tris-CAR-T cell.

Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Tasly Pharmaceutical Group Co., Ltd

Recurrent Glioblastoma

11/24

11/32

NCT06515938: Study on New Strategies for Hepatitis B Virus Immunization

Completed

N/A

1169

RoW

20μg Engerix-B hepatitis B vaccine, 20μg Kangtai hepatitis B vaccine, 60μg Kangtai hepatitis B vaccine, 20μg CHO

Wu Jiang

Vaccine Reaction

06/14

12/15

NCT05159804: Association Between Carotid Plaque Length and Cardiovascular Events

Active, not recruiting

N/A

3637

RoW

Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine

Coronary Arteriosclerosis

06/21

12/30

ROX-1, NCT04707729: ROX Index for the Timing of Intubation in Nasal High Flow

Recruiting

N/A

630

Europe, US, RoW

ROX index algorithm

Hospital Universitari Vall d'Hebron Research Institute

Acute Hypoxemic Respiratory Failure

12/24

06/25

NCT05843487: Association Between Carotid Plaque Length and Cardiovascular Outcomes

Active, not recruiting

N/A

3000

RoW

Changhai Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital

Coronary Artery Disease, Carotid Plaque

03/22

12/30

NCT03958435: Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery

Recruiting

N/A

20000

RoW

Second Affiliated Hospital, School of Medicine, Zhejiang University

Stage II Colon Cancer, Stage III Colon Cancer, Adjuvant Therapy

10/22

12/23

NCT04714918: Chinese CKD-MBD Prevalence Survey (CRISS-MBD)

Recruiting

N/A

10254

RoW

Limeng Chen

Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder

12/24

NCT05485857: Influence of Arrangement of Small Intestine Order on the Recovery of Bowel Function After Laparoscopic Colorectal Surgery

Completed

N/A

160

RoW

Arrangement of small intestine order before close the abdomen

Changhai Hospital

Postoperative Complications

02/23

03/23

NCT05634473: A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test

Not yet recruiting

N/A

280

RoW

Methacholine Chloride

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Asthma

02/23

06/23

NCT04853238: Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China

Completed

N/A

1507

RoW

Prospective observational cohort study

GlaxoSmithKline

Pulmonary Disease, Chronic Obstructive

11/22

02/23

ZCFZZLXGBDFYHZ, NCT05692258: Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia

Recruiting

N/A

146

RoW

Acupuncture, basic therapy

The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine

Acupuncture, Covid-19 Omicron, Pulmonary Function

04/23

NCT05752097: [18F]AlF-NOTA-FAPI-04 PET/CT in Inflammation and Fibrosis in Renal Diseases

Recruiting

N/A

RoW

[18F]AlF-NOTA-FAPI-04 PET/CT examination, Renal puncture biopsy

Sichuan Provincial People's Hospital

18F-FAPI PET/CT Examination, Renal Puncture Biopsy

08/24

11/24

GJZLBQGNZA, NCT05749354: Clinical Efficacy of Acupuncture on the Liver Meridian in Men With Erectile Dysfunction Reserve

Recruiting

N/A

159

RoW

electroacupuncture, acupuncture

The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine

Erectile Dysfunction, Acupuncture Therapy, Median Nerve Disease

12/23

PCOS, NCT04984070: Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety

Recruiting

N/A

100

RoW

Oral Contraceptives, Combined, Danie-35, Drospirenone and Ethinylestradiol Tablets (I), Drospirenone and Ethinylestradiol Tablets (Ⅱ), Metformin Pill, Metformin, lifestyle intervention

Fudan University

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety

12/23

12/24

NCT05183425: Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis

Recruiting

N/A

RoW

Changhai Hospital

Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases

12/23

12/24

GJZLLCCBGNXJ, NCT05743218: Clinical Efficacy of Acupuncture on the Liver Meridian in Women With Diminished Ovarian Reserve

Recruiting

N/A

198

RoW

electropuncture, acupuncture

The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine

Ovarian Reserve, Acupuncture Therapy, Meridian

12/23

NCT05815069: [18F]AlF-NOTA-pentixather PET/CT in Patients With Suspected Primary Hyperaldosteronism

Recruiting

N/A

RoW

[18F]AlF-NOTA-pentixather PET/CT, pathological examination

Sichuan Provincial People's Hospital

Aldosterone-Producing Adenoma

01/24

06/24

NCT06481826: Glofitamab in Chinese Patients With R/R DLBCL

Recruiting

N/A

RoW

Glofitamab

Peking Union Medical College Hospital

DLBCL - Diffuse Large B Cell Lymphoma

12/27

12/28

NCT06254716: A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis

Recruiting

N/A

RoW

disc resection, segmental resection

Fudan University

Gastrointestinal Function, Quality of Life, Pregnancy Outcomes

12/24

proOMCRC, NCT04716257: A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients

Recruiting

N/A

400

RoW

West China Hospital, Sun Yat-sen University, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Changhai Hospital, Naval Medical University

Ovarian Metastasis, Colorectal Cancer

09/25

NCT06204497: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients

Recruiting

N/A

570

RoW

Stent-based Diverting Technique

Sir Run Run Shaw Hospital

Rectal Neoplasms

12/24

06/25

VERONICA, NCT05486923: Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population

Recruiting

N/A

450

RoW

Huashan Hospital

Glioma, Patient Reported Outcome Measures, Self Report, Adverse Effects

04/25

12/25

NCT05882552: Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle Palsy

Not yet recruiting

N/A

Tilted Gaze Target Tast, Conventional Examination Methods

Tianjin Eye Hospital

Children With Torticollis

06/24

12/24

NCT06510127: An AI Model Predicts the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer: a Multicenter, Bidirectional Cohort Study

Enrolling by invitation

N/A

840

RoW

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Jinan University

Breast Cancer

06/25

01/26

NCT03651986: Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules

Active, not recruiting

N/A

10560

RoW

ctDNA methylation analysis by NGS

AnchorDx Medical Co., Ltd., Xiangya Hospital of Central South University, West China Hospital, Shanghai Zhongshan Hospital, Shanghai Pulmonary Hospital affiliated to Tongji University, First Hospital of China Medical University, Guizhou Provincial People's Hospital, Shanghai Chest Hospital, First Affiliated Hospital, Sun Yat-Sen University, First Affiliated Hospital Xi'an Jiaotong University, Qilu Hospital of Shandong University, Inner Mongolia People's Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of Zhengzhou University, Second Hospital of Jilin University, LanZhou University, Peking University Third Hospital, The First People's Hospital of Yunnan, Shantou Affiliated Hospital of Sun Yat-Sen University, Ruijin Hospital, The Shanghai Jiao Tong University Medical School, Tongji Hospital, The First Affiliated Hospital of Guangzhou Medical University, Xijing Hospital, Air Force Medical University of PLA, Shenzhen People's Hospital, Henan Provincial People's Hospital, Beijing Chao Yang Hospital, Xiamen Second Hospital, The First Affiliated Hospital of Nanchang University

Pulmonary Nodules

09/24

06/25

NCT05514327: A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL

Recruiting

N/A

RoW

ultra-fraction radiotherapy

Peking Union Medical College Hospital

Diffuse Large B Cell Lymphoma, CAR-T, Radiotherapy, Bridging Therapy

09/24

12/24

NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM).

Not yet recruiting

N/A

1000

RoW

Continuous Glucose Monitoring System (GX-01S)

Nanjing First Hospital, Nanjing Medical University

Type1 Diabetes Mellitus

10/26

06/27

NCT04837222: A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma

Active, not recruiting

N/A

1000

RoW

No Intervention

Takeda

Lymphoma

06/26

NCT06723366: Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After Cardiovascular Surgery

Not yet recruiting

N/A

120

RoW

Angong Niuhuang Pill (ANP), Control (Standard treatment)

Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital, Capital Medicine University

Cardio-pulmonary Bypass, Cardiovascular Surgery, Cerebral Protection, Brain Injury

12/25

NCT05818267: Efficacy and Safety of Regorafenib Maintenance Therapy in Patients With Metastatic Colorectal Cancer (mCRC)

Recruiting

N/A

RoW

Regorafenib

Wei Zhang

Colorectal Cancer

03/25

11/25

NCT05282095: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China

Recruiting

N/A

300

RoW

Follow up

Fujian Maternity and Child Health Hospital

Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions

12/25

05/26

AIM, NCT05032053: Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds

Recruiting

N/A

3000

RoW

Antithrombotic drugs

Xijing Hospital, Ankang Central Hospital, Yan'an University Affiliated Hospital

Ischemic Stroke

12/25

10/26

LPS-IHH, NCT05569577: An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients

Recruiting

N/A

RoW

Additional hCG injection, estrogen and dydrogesterone

Fudan University

Luteal Phase Deficiency, Luteal Phase Support, Idiopathic Hypogonadotropic Hypogonadism

12/25

NCT05923255: LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer

Recruiting

N/A

568

RoW

LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）, TRH（Traditional Laparoscopic Right Hemicolectomy）

Zhejiang University

Hepatic Flexure Colon Cancer, Proximal Transverse Colon Cancer

05/26

05/31

COAST, NCT03653156: China Cognition and Aging Study

Recruiting

N/A

100000

RoW

Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Afﬁliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital

Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia

01/38

CFAN, NCT03657732: The Chinese Familial Alzheimer's Network

Recruiting

N/A

40000

RoW

Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Afﬁliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital

Alzheimer Disease, Familial Alzheimer Disease (FAD)

01/38

NCT05409209: Carotid Plaque Length to Predict Cardiovascular Events

Active, not recruiting

N/A

3000

RoW

Coronary Artery Disease

12/21

12/30

NCT05513664: Real-World Effectiveness of Osimertinib for Patients With Non-Small Cell Lung Cancer

Not yet recruiting

N/A

RoW

Osimertinib

Shanghai JMT-Bio Inc., CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Locally Advanced or Metastatic Non-Small Cell Lung Cancer, EGFR Exon20 Insertion Mutations

06/23

08/23

Freeman, Michael

TAK-279-PsO-3003, NCT06550076: A Study of TAK-279 in Participants With Moderate-to-Severe Plaque Psoriasis

Recruiting

1300

Europe, Canada, Japan, US, RoW

TAK-279

Takeda

Plaque Psoriasis

05/26

NCT06088043: A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment

Active, not recruiting

693

Europe, Canada, Japan, US, RoW

TAK-279, Placebo, Apremilast

Takeda

Plaque Psoriasis

08/25

04/26

Zhang, Jun

HEARTRIP, NCT03809273: Effects of Yangxinshi Pills on the Exercise Tolerance Compared With Trimetazidine in Patients After PCI

Recruiting

668

RoW

Yangxinshi, Trimetazidine, Yangxinshi mimic, Trimetazidine mimic

Shenyang Northern Hospital

Percutaneous Coronary Intervention

12/20

NCT05181475: Long-term Efficacy and Safety Study of GV-971

Active, not recruiting

800

RoW

Sodium Oligomannate Capsules (GV-971)

Green Valley (Shanghai) Pharmaceuticals Co., Ltd.

Alzheimer Disease

01/25

06/25

NCT06565715: Effect of Remazolam on Hemodynamics During Hepatectomy

Recruiting

RoW

Remimazolam, rebenin, Propofol, Propofol emulsion

Jun Zhang

Hemodynamic Instability

10/24

11/24

NCT03491059: Feasibility of PET/CT to Detect the Oral/Pulmonary Distribution of Nicotine Following E-cigarette Use

Active, not recruiting

C-11 labeled nicotine, PET/CT imaging

University of Cincinnati

E-cigarette Use

12/24

02/25

OPTIMA-6, NCT05410925: Efficacy and Safety of a Half-dose Bolus of r-SAK Prior to Primary PCI in ST-elevation Myocardial Infarction

Recruiting

2260

RoW

Recombinant staphylokinase, Placebo

The First Affiliated Hospital with Nanjing Medical University

ST Elevation Myocardial Infarction

12/26

12/27

NCT04624854: Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD)

Active, not recruiting

8250

RoW

Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy

Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd.

Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases

04/25

NCT04782895: Immunogenicity of a Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58)Vaccine(E.Coli) Versus Gardasil®9 in Healthy Females 18-26 Years of Age

Completed

488

RoW

Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), Gardasil®9

Xiamen University, Xiamen Innovax Biotech Co., Ltd, Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Cervical Cancer, Condylomata Acuminata

05/22

07/22

NCT04714190: A Study of RC48-ADC in Local Advanced or Metastatic Gastric Cancer With the HER2-Overexpression

Recruiting

351

RoW

RC48-ADC, Recombinant Humanized anti-HER2 Monoclonal Antibody-MMAE Conjugate For Injection, Paclitaxel injection, Taxol, Irinotecan Hydrochloride Injection, CAMPTO, Apatinib Mesylate Tablets, Aitan

RemeGen Co., Ltd.

Gastric Cancer, HER2 Overexpressing Gastric Carcinoma

12/24

06/25

PYRAMID-1, NCT04447118 / 2020-000951-11: Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

Active, not recruiting

151

Europe, US, RoW

Pyrotinib, Irene, Docetaxel, Docetaxel injection

Jiangsu HengRui Medicine Co., Ltd.

Non-squamous NSCLC, HER2 Exon 20 Mutation

06/23

10/23

SPH3127-301, NCT05359068: Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension

Completed

957

RoW

SPH3127 tablet, Valsartan

Shanghai Pharmaceuticals Holding Co., Ltd

Essential Hypertension

12/23

NCT04674956: A Prospective, Randomized, Double-blinded, Multi-center Clinical Trial to Evaluate the Efficiency and Safety of Anti-PD1 Antibody (Camrelizumab) Combined With Paclitaxel(Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancer

Recruiting

401

RoW

Camrelizumab, Paclitaxel(Albumin Bound) and Gemcitabine, Placebo

RenJi Hospital

Pancreatic Cancer Stage IV, Pancreatic Cancer Metastatic

12/24

12/25

NCT05056402: An Immuno-bridging Study of a Nonavalent HPV Vaccine (E.Coli) in Healthy Population Aged 9-17 vs Aged 18-26 Years Old

Active, not recruiting

1382

RoW

3 doses of the Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), 2 doses of theRecombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)

Xiamen Ophthalmology Center Affiliated to Xiamen University, Xiamen Innovax Biotech Co., Ltd, Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Cervical Cancer, Condylomata Acuminata

12/25

NCT05352516 / 2022-002188-31: A Study to Evaluate the Efficacy and Safety of HLX14 vs. Denosumab Prolia® in Postmenopausal Women With Osteoporosis at High Risk of Fracture

Completed

514

RoW

HLX14, Prolia®

Shanghai Henlius Biotech, Shanghai Henlius Biotech, Inc.

Postmenopausal

12/23

07/24

HERIZON-GEA-01, NCT05152147 / 2021-000296-36: A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Recruiting

918

Europe, Canada, Japan, RoW

Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil

Jazz Pharmaceuticals, BeiGene, Ltd.

Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma

05/25

05/26

NCT06472908: Efficacy and Safety of Colchicine After PCI

Not yet recruiting

8862

RoW

Colchicine 0.5 mg, no other name, Colchicine 0.375 mg, Placebo

Wuhan Union Hospital, China

Coronary Heart Disease, Percutaneous Coronary Intervention, Colchicine

03/28

08/28

ACCIO, NCT04267848: Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

Recruiting

1210

US, RoW

Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Gemcitabine Hydrochloride, dFdCyd, Difluorodeoxycytidine Hydrochloride, Gemcitabine HCI, Gemzar, LY 188011, LY-188011, LY188011, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Observation, Inspection, Visual Inspection, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475, Pemetrexed Disodium, Alimta, Almita, LY231514, N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt, Questionnaire Administration

National Cancer Institute (NCI)

Lung Non-Small Cell Carcinoma, Lung Non-Small Cell Squamous Carcinoma, Lung Non-Squamous Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8

12/25

NCT05768503: Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC

Recruiting

176

RoW

Experimental drug, CAP, Control Rx, FOLFIRI+BEV

Sun Yat-sen University

Metastatic Microsatellite-stable Colorectal Cancer

01/26

01/27

NCT05180734: PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer

Active, not recruiting

878

RoW

JS001/Placebo, Postoperative Adjuvant Chemotherapy, JS001/placebo combine with Postoperative Adjuvant Chemotherapy

Shanghai Junshi Bioscience Co., Ltd.

Gastric or Esophagogastric Junction Adenocarcinoma

06/26

07/28

SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Recruiting

1016

Europe, Canada, Japan, US, RoW

LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed

Eli Lilly and Company, Loxo Oncology, Inc.

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

10/26

10/29

NCT05918094: Comparing Modified XELOX Plus Sintilimab With Standard XELOX Plus Sintilimab in First-line Treatment for HER2-negative Gastric/Gastroesophageal Junction Adenocarcinoma

Recruiting

540

RoW

Experimental dose: modified XELOX + sintilimab, Standard dose: standard XELOX + sintilimab

Sun Yat-sen University

Gastric Cancer

12/26

12/28

NCT04181060: Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Recruiting

300

Bevacizumab, ABP 215, ABP-215, ABP215, Alymsys, Anti-VEGF, Anti-VEGF Humanized Monoclonal Antibody, Anti-VEGF Monoclonal Antibody SIBP04, Anti-VEGF rhuMAb, Avastin, Avzivi, Aybintio, BAT 1706, BAT-1706, BAT1706, BAT1706 Biosimilar, Bevacizumab awwb, Bevacizumab Biosimilar ABP 215, Bevacizumab Biosimilar BAT1706, Bevacizumab Biosimilar BEVZ92, Bevacizumab Biosimilar BI 695502, Bevacizumab Biosimilar CBT 124, Bevacizumab Biosimilar CT-P16, Bevacizumab Biosimilar FKB238, Bevacizumab Biosimilar GB-222, Bevacizumab Biosimilar HD204, Bevacizumab Biosimilar HLX04, Bevacizumab Biosimilar IBI305, Bevacizumab Biosimilar LY01008, Bevacizumab Biosimilar MB02, Bevacizumab Biosimilar MIL60, Bevacizumab Biosimilar Mvasi, Bevacizumab Biosimilar MYL-1402O, Bevacizumab Biosimilar QL 1101, Bevacizumab Biosimilar QL1101, Bevacizumab Biosimilar RPH-001, Bevacizumab Biosimilar SCT501, Bevacizumab Biosimilar Zirabev, Bevacizumab-adcd, Bevacizumab-awwb, Bevacizumab-aybi, Bevacizumab-bvzr, Bevacizumab-equi, Bevacizumab-maly, Bevacizumab-onbe, Bevacizumab-tnjn, BP102, BP102 Biosimilar, CT P16, CT-P16, CTP16, Equidacent, FKB 238, FKB-238, FKB238, HD204, Immunoglobulin G1 (Human-Mouse Monoclonal rhuMab-VEGF Gamma-Chain Anti-Human Vascular Endothelial Growth Factor), Disulfide With Human-Mouse Monoclonal rhuMab-VEGF Light Chain, Dimer, MB 02, MB-02, MB02, Mvasi, MYL-1402O, Onbevzi, Oyavas, PF 06439535, PF-06439535, PF06439535, QL1101, Recombinant Humanized Anti-VEGF Monoclonal Antibody, rhuMab-VEGF, SCT501, SIBP 04, SIBP-04, SIBP04, Vegzelma, Zirabev, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Osimertinib, AZD 9291, AZD-9291, AZD9291, Mereletinib

National Cancer Institute (NCI)

Advanced Lung Non-Squamous Non-Small Cell Carcinoma, Metastatic Lung Non-Squamous Non-Small Cell Carcinoma, Recurrent Lung Non-Squamous Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8

12/26

NCT04537156: Efficacy, Immunogenicity and Safty Study of Recombinant Human Papillomavirus Vaccine(6,11,16,18,31,33,45,52,58 Type)(E.Coli)

Active, not recruiting

9327

RoW

Nonavalent HPV vaccine, Bivalent HPV vaccine

Xiamen University, Xiamen Innovax Biotech Co., Ltd, Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Cervical Intraepithelial Neoplasia, Cervical Cancer, Condylomata Acuminata

12/27

NCT03959150: Metronomic Chemotherapy With Capecitabine for Pancreatic Cancer

Recruiting

2/3

231

RoW

Capecitabine, Xeloda

Ruijin Hospital

Pancreatic Cancer

06/22

06/23

NCT02942706: Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC

Not yet recruiting

2/3

200

Cetuximab, Erbitux, mFOLFOX6, FOLFIRI

Ruijin Hospital, Chinese PLA General Hospital, Xiangya Hospital of Central South University, West China Hospital, Tongji Hospital

Colorectal Cancer

10/22

NCT06221748: DV Combined With Cadonilimab in Subjects With HER2-expressing Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on First-line Therapy

Recruiting

2/3

RoW

Disitamab Vedotin Injection, DV,RC48, Cadonilimab Injection, AK104, Cadonilimab Injection, Paclitaxel Injection

RemeGen Co., Ltd.

Gastric Cancer, Gastroesophageal Junction Adenocarcinoma

12/26

12/27

NRG-HN009, NCT05050162: Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Recruiting

2/3

464

Europe, Canada, US, RoW

Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Radiation Therapy, Cancer Radiotherapy, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation

NRG Oncology, National Cancer Institute (NCI)

Advanced Head and Neck Squamous Cell Carcinoma, Advanced Hypopharyngeal Squamous Cell Carcinoma, Advanced Laryngeal Squamous Cell Carcinoma, Advanced Oropharyngeal Squamous Cell Carcinoma, Squamous Cell Carcinoma of Unknown Primary

02/31

02/36

NCT04869475: Arsenic Trioxide in Refractory Solid Tumors With Rescuable p53 Mutation

Recruiting

RoW

Arsenic trioxide

Ruijin Hospital

Refractory Solid Tumors

04/22

04/24

NCT03126071: Raltitrexed-based Chemotherapy Plus Bevacizumab in Retreated Patients With Advanced Colorectal Cancer

Recruiting

100

RoW

Raltitrexed, Irinotecan, Oxaliplatin, Bevacizumab, Avastin

Jiangsu Cancer Institute & Hospital

Advanced Colorectal Cancer

08/22

02/23

ALTER-G-001, NCT05262335: Anlotinib Plus Chemotherapy as First-line Therapy for Gastrointestinal Tumor Patients With Unresectable Liver Metastasis

Recruiting

116

RoW

Anlotinib + Oxaliplatin + Capecitabine, Anlotinib + Cisplatin + Paclitaxel/ Docetaxel, Anlotinib + Standard first-line chemotherapy

Ruijin Hospital, Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Gastrointestinal Tumors

12/23

12/24

NCT02710851: Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine

Active, not recruiting

640

low dosage HPV Vaccine(1:1), low dosage HPV Vaccine(1:2), high dosage HPV Vaccine(1:1), Hepatitis E vaccine,Hecolin®

Jun Zhang, Xiamen Innovax Biotech Co., Ltd, Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.

Condylomata Acuminata

12/23

ACHIEVE, NCT04808752: Almonertinib as First-line Treatment in Patients With EGFR Mutations Positive in Advanced NSCLC With Brain Metastases

Active, not recruiting

RoW

Almonertinib, Investigational Product

Zhejiang Cancer Hospital, Jiangsu Hansoh Pharmaceutical Co., Ltd.

Lung Cancer

06/24

07/24

Ipat-Lung, NCT04467801: Ipatasertib and Docetaxel in Metastatic NSCLC Patients Who Have Failed 1st Line Immunotherapy

Recruiting

Ipatasertib

Jun Zhang, MD, PhD, University of Iowa, University of Kentucky

NSCLC Stage IV, NSCLC Stage IIIB

08/24

08/25

TQB2102-II-04, NCT06767800: A Clinical Trial Evaluating TQB2102 for Injection in Combination With Benmelstobart/Penpulimab With or Without Capecitabine in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma

Not yet recruiting

168

RoW

TQB2102 for injection+Benmelstobart, TQB2102 for injection+Benmelstobart+Capecitabine

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.

Gastroesophageal Adenocarcinoma

09/26

09/27

Cabatezo-1, NCT05859217: A Study of Combining Cabozantinib and Atezolizumab for Advanced/Metastatic NSCLC

Not yet recruiting

Cabozantinib, Cabometyx, Atezolizumab, Tecentriq

Jun Zhang, MD, PhD, Exelixis, Genentech, Inc.

Lung Cancer, NSCLC Stage IV, Metastatic NSCLC - Non-Small Cell Lung Cancer, Advanced NSCLC

06/26

06/28

CA239-0010, NCT05609578: Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

Recruiting

Europe, US, RoW

Adagrasib oral dose of 400 mg twice daily tablets, Pembrolizumab, Chemotherapy: Pemetrexed, Cisplatin/Carboplatin

Mirati Therapeutics Inc.

Advanced NSCLC, Metastatic Lung Cancer

06/26

12/26

TranStar102, NCT04495296: A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors

Recruiting

1/2

320

RoW

TST001, Oxaliplatin, Capecitabine, Paclitaxel, Gemcitabine, Cisplatin, Nivolumab

Suzhou Transcenta Therapeutics Co., Ltd., Bristol-Myers Squibb

Advanced Cancer

02/25

05/25



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