UVM/FAHC
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 8 Trials 
12 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Sholler, Giselle
NCT01586260: Preventative Trial of DFMO in Patients With High Risk Neuroblastoma in Remission

Active, not recruiting
2
89
US
DFMO, eflornithine HCl, Difluoromethylornithine
Giselle SaulnierSholler, Cancer Prevention Pharmaceuticals, Inc., University of Arizona, University of Hawaii, University of Vermont, Beat NB Cancer Foundation
Neuroblastoma
04/21
04/21
NMTT, NCT02679144: Neuroblastoma Maintenance Therapy Trial

Recruiting
2
441
Canada, US
Difluoromethylornithine (DFMO), eflornithine
Giselle Sholler, Beat NB Cancer Foundation, Team Parker for Life
Neuroblastoma
02/28
02/33
NCT04301843: Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

Recruiting
2
131
Canada, US
Eflornithine, DFMO, difluoromethylornithine
Giselle Sholler, K C Pharmaceuticals Inc., Beat NB Cancer Foundation, Team Parker for Life
Neuroblastoma
10/28
10/33
PEDS-PLAN, NCT02559778: Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

Recruiting
2
500
Canada, US
Ceritinib, Zykadia, dasatinib, Sprycel, sorafenib, Nexavar, vorinostat, ZOLINZA, DFMO, Eflornithine, α-difluoromethylornithine
Giselle Sholler, Dell, Inc., Beat NB Cancer Foundation, K C Pharmaceuticals Inc., Team Parker for Life
Neuroblastoma
09/30
09/35
NCT06465199: Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomas

Not yet recruiting
1/2
253
NA
Difluoromethylornithine (DFMO), Eflornithine, AMXT-1501 Dicaprate
Milton S. Hershey Medical Center, Aminex Therapeutics, Inc.
Atypical Teratoid/Rhabdoid Tumor, Neuroblastoma Recurrent, Embryonal Tumor With Multilayered Rosettes, DIPG Brain Tumor, Ewing Sarcoma, Osteosarcoma Recurrent
02/33
02/35
NCT04238819: A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Active, not recruiting
1/2
117
Europe, Japan, US, RoW
Abemaciclib, LY2835219, Irinotecan, Temozolomide, Dinutuximab, GM-CSF
Eli Lilly and Company
Relapsed Solid Tumor, Refractory Solid Tumor
03/24
04/25
NCT04023331: 67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma

Recruiting
1/2
34
US
67Cu-SARTATE, Cu-67 SARTATE, copper 67 SARTATE, 64Cu-SARTATE, Cu-64 SARTATE, copper 64 SARTATE
Clarity Pharmaceuticals Ltd
Neuroblastoma, Relapsed Neuroblastoma, Refractory Neuroblastoma
12/28
12/28
PEACH, NCT04837547: TRIAL- Precision Medicine and Adoptive Cellular Therapy

Recruiting
1
24
US
Tumor-specific ex vivo expanded autologous lymphocyte transfer (TTRNA-xALT), xALT
University of Florida, Beat Childhood Cancer Research Consortium
Neuroblastoma, Diffuse Intrinsic Pontine Glioma
09/25
09/30
NCT03581240: An Intermediate Expanded Use Trial of DFMO

Available
N/A
US
eflornithine HCl, DFMO
Giselle Sholler, K C Pharmaceuticals Inc., USWM, LLC
Neuroblastoma, Medulloblastoma, Typical Teratoid Rhabdoid Tumor, Embryonal Tumor With Abundant Neuropil and True Rosettes, Ependymoblastoma, Medulloepithelioma
 
 
NCT01802567: Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer

Completed
N/A
52
US
Guided Therapy- Pediatric Gene Analysis Platform, Molecular Guided Therapy
Giselle Sholler, Dell, Inc.
Neuroblastoma, Medulloblastoma, Brain Tumors, Rare Tumors
01/24
01/24
NCT02162732: Molecular-Guided Therapy for Childhood Cancer

Completed
N/A
186
US, RoW
Guided Therapy
Giselle Sholler, Translational Genomics Research Institute, Dell, Inc.
Neuroblastoma, Medulloblastoma, Glioma, Ependymoma, Choroid Plexus Neoplasms, Craniopharyngioma, Dysembryoplastic Neuroepithelial Tumor, Meningioma, Primitive Neuroectodermal Tumors (PNETs), Germ Cell Tumors, Rhabdomyosarcoma, Non-rhabdomyosarcoma, Ewings Sarcoma, Osteosarcoma, Wilms Tumor, Renal Cell Carcinoma, Malignant Rhabdoid Tumor, Clear Cell Sarcoma, Liver Tumors
01/24
01/24
NCT04715178: Beat Childhood Cancer Specimen Banking and Data Registry

Recruiting
N/A
500
US
No intervention- registry only
Giselle Sholler
Pediatric Cancer
01/31
01/32

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