| RUFFION, Alain |
NCT03850795: HC-1119 Versus Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC) |
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| Terminated | 3 | 104 | Europe, Canada, US, RoW | HC-1119, Enzalutamide | Hinova Pharmaceuticals USA, Inc. | Prostate Cancer Metastatic, Castration-resistant Prostate Cancer | 06/24 | 06/24 | | |
| Active, not recruiting | 3 | 517 | Europe | BCG, Bacillus Calmette Guerin (BCG) Medac®, OncoTice, Atezolizumab, MPDL3280A, Tecentriq® | UNICANCER, Hoffmann-La Roche | Bladder Cancer | 06/25 | 10/28 | | |
| Active, not recruiting | 3 | 761 | Europe | Cabazitaxel, jevtana, Pelvic radiotherapy, prostate radiotherapy | UNICANCER, Sanofi | Adenocarcinoma of Prostate, Progression of Prostate Cancer | 12/25 | 07/41 | | |
HIFUSA, NCT03531099: Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer |
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| Active, not recruiting | 3 | 108 | Europe | treatment with focal HIFU, PSA dosage, MRI, Questionnaires, Prostatic biopsies | Hospices Civils de Lyon | Prostate Cancer | 10/25 | 10/26 | | |
FOCALE, NCT03568188: Efficacy Evaluation of Focused HIFU (High Intensity Focused Ultrasound) Therapy in Patients With Localized Intermediate Risk Prostate Cancer |
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| Active, not recruiting | 2 | 170 | Europe | treatment with focal HIFU, PSA dosage, MRI, Questionnaires, Prostatic biopsies, blood test, urine test | Hospices Civils de Lyon | Prostate Cancer | 09/25 | 09/25 | | |
NCT05207189: Biological Sling Allograft (UVT) for the Treatment of Urinary Incontinence in Women Presenting With Synthetic Sling Complications |
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| Completed | 2 | 16 | Europe | UVT | TBF Genie Tissulaire | Female Stress Incontinence, Stress Urinary Incontinence | 03/24 | 03/24 | | |
SUGAR, NCT05826509: SUrGery with or Without DARolutamide in High-risk And/or Locally Advanced Prostate Cancer |
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| Recruiting | 2 | 240 | Europe | Surgery alone, Peri-operative darolutamide + surgery. | Institut Claudius Regaud, Bayer | Prostate Cancer | 05/30 | 05/30 | | |
AMBULAPSE, NCT03764852: STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistance, in Female Patients Presenting With Symptomatic Pelvic Organ Prolapse, Based on an Outpatient Treatment Model. |
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| Recruiting | N/A | 80 | Europe | outpatient laparoscopic | Centre Hospitalier Universitaire de Nice | Pelvic Organ Prolapse | 09/24 | 12/24 | | |
PRODUCAN, NCT03572621: Development and Evaluation of a Therapeutic Education Intervention in Prostate Cancer Patients Treated With Radical Prostatectomy to Improve Their Sexuality |
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| Recruiting | N/A | 240 | Europe | Therapeutic education, Collection of data concerning their sexuality, Participation | Hospices Civils de Lyon | Prostate Cancer | 02/23 | 09/24 | | |
| Active, not recruiting | N/A | 1360 | Europe | Comparisons between the Prostatic urethral lift (PUL) and the TURP/Laser cohorts, Comparison between the Prostatic urethral lift (PUL) and the SNDS cohorts | University Hospital, Bordeaux, Bordeaux PharmacoEpi | Benign Prostatic Hyperplasia | 12/24 | 06/26 | | |
| Recruiting | N/A | 346 | Europe | F-HIFU, Radical Prostatectomy | University Hospital, Bordeaux | Prostate Cancer | 02/25 | 02/27 | | |
| Active, not recruiting | N/A | 180 | Europe, RoW | Questionnaires on Urinary Incontinence-, Sex Function- and Quality of Life (ICIQ-UI-SF, ICIQ-FLUTSsex, ICIQ-LUTSqol, PGI-I) | European Association of Urology Research Foundation, Boston Scientific Corporation | Urinary Incontinence, Urinary Incontinence, Stress, Lower Urinary Tract Symptoms, Urination Disorders, Urologic Diseases | 06/25 | 12/26 | | |
ACTI-PAIR2, NCT05739565: Impact of a Physical Activity Intervention With Motivational Support From Peers for Prostate Cancer Patients |
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| Recruiting | N/A | 850 | Europe | Acti-Pair program | Centre Hospitalier Universitaire de Saint Etienne, Sport Health Center of Auvergne-Rhône Alpes, INSERM, SAINBIOSE U1059, INSERM, CIC1408, INSERM ECEVE 1123, Ministry of Health, France | Prostate Cancer | 09/25 | 09/26 | | |
CHANGE, NCT04732156: Detection of ISUP≥2 Prostate Cancers Using Multiparametric MRI: Prospective Multicenter Comparison of the PI-RADS Score and an Artificial Intelligence System |
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| Recruiting | N/A | 420 | Europe | Blood sample, Follow up questionnaire, Human reading of prostate MR images (PI-RADSv2.1). | Hospices Civils de Lyon | Prostate Cancer | 06/26 | 06/26 | | |
| Cuzin, Béatrice |
PRODUCAN, NCT03572621: Development and Evaluation of a Therapeutic Education Intervention in Prostate Cancer Patients Treated With Radical Prostatectomy to Improve Their Sexuality |
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| Recruiting | N/A | 240 | Europe | Therapeutic education, Collection of data concerning their sexuality, Participation | Hospices Civils de Lyon | Prostate Cancer | 02/23 | 09/24 | | |
| BERTRAND, Yves |
| Recruiting | 3 | 149 | Europe | Multivirus (CMV, EBV, AdV)-specific T cells | Prof. Tobias Feuchtinger, European Commission, Simbec-Orion Group Ltd, Merthyr Tydfil, UK, Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany, Leiden University Medical Center, LUMC, Leiden, The Netherlands, Centre Hospitalier Universitaire de Nancy, CHU, Vandoeuvre-Lès-Nancy, France, Ghent University Hospital, UZG, Ghent, Belgium, Ospedale Pediatrico Bambino Gesù, OPBG, Rome, Italy, Newcastle University, UNEW, Newcastle, UK, Vall d'Hebron Institute of Oncology (VHIO) and Banc de Sang I Teixits (BST), Barcelona, Spain | AdV Infection, EBV Infection, CMV Infection, Stem Cell Transplant Complications | 06/24 | 12/24 | | |
CAALL-F01, NCT02716233: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents |
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| Recruiting | 3 | 1578 | Europe | pegaspargase 1250 IU/m2 x 2, ONCASPAR 1250 IU/m2 x 2, pegaspargase 2500 IU/m2 x 1, ONCASPAR 2500 IU/m2 x 1 | Assistance Publique - Hôpitaux de Paris, Shire | Acute Lymphoblastic Leukemia | 04/26 | 04/26 | | |
| Recruiting | 2/3 | 1800 | Europe, Canada, RoW | VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin | St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group | Acute Lymphoblastic Leukaemia | 06/25 | 04/30 | | |
| Completed | N/A | 72 | Europe | blood sample, Pulse wave velocity | Hospices Civils de Lyon | Hereditary Spherocytosis | 08/22 | 08/22 | | |
| Active, not recruiting | N/A | 2093 | Europe, RoW | Hydroxycarbamide, Siklos, Hydroxyurea | Theravia, International Clinical Trials Association | Sickle Cell Disease | 08/25 | 08/25 | | |
MICCHADO, NCT03496402: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults |
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| Active, not recruiting | N/A | 600 | Europe | Sampling on blood, bone marrow and cerebrospinal fluid | Institut Curie | Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor | 04/27 | 08/27 | | |
| Recruiting | N/A | 5000 | Europe | | The Lymphoma Academic Research Organisation, Gilead Sciences, Novartis, Bristol-Myers Squibb | Hematopathology Eligible or CAR-t Cell Treatment | 12/38 | 12/38 | | |
| RIMMELE, Thomas |
RICO, NCT04392401: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric Non Interventional Study |
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| Recruiting | N/A | 200 | Europe | Collection of blood samples in order to create a biocollection | Hospices Civils de Lyon, BioMérieux | Intensive Care Unit, SARS-Cov-2 | 05/22 | 05/22 | | |
| Not yet recruiting | N/A | 5000 | Europe | questionnaire filling | Centre Hospitalier Universitaire de NÄ«mes | Critical Illness, Covid19, Stress Disorders, Post-Traumatic | 09/22 | 09/22 | | |
CovidEP, NCT04751643: Therapeutic Plasma Exchange to Alleviate Hyperinflammatory Condition During Severe Covid-19 Infections |
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| Recruiting | N/A | 132 | Europe | Therapeutic plasma exchange : 3 sessions in 3 consecutive days (day 1 to day 3), Usual treatments in intensive care unit according to the current state of knowledge | Hospices Civils de Lyon | Intensive Care Units, ARDS, Human, Covid19 | 12/22 | 12/22 | | |
ECRO, NCT03426943: Endotoxins and Cytokines Removal During Continuous Hemofiltration With oXiris™ |
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| Completed | N/A | 39 | Europe | Arterial blood sampling, Ultrafiltrate sampling, CVVH using oXiris™ filter, CVVH using PrismafleX HF1400 filter | Hospices Civils de Lyon, Baxter Healthcare Corporation | Septic Shock, Peritonitis | 06/22 | 06/22 | | |
VT4COVID, NCT04349618: Ultraprotective Ventilation Without Extracorporeal Circulation During COVID 19 Pneumonia |
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| Recruiting | N/A | 200 | Europe | PROTECTIVE VENTILATION, ULTRAPROTECTIVE VENTILATION | Hospices Civils de Lyon | Acute Respiratory Distress Syndrome, COVID19, Sars-CoV2, Pneumonia | 04/23 | 04/23 | | |
EarlyDry, NCT05817539: Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute Renal Failure |
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| Recruiting | N/A | 250 | Europe | Fluid balance negativation, Body weight Stabilization | Hospices Civils de Lyon | Acute Kidney Injury, Fluid Overload | 01/26 | 01/26 | | |
| DAVID, Jean-Stephane |
| Not yet recruiting | 3 | 1218 | Europe | direct IV injection, combination of Ketamine and Propofol | Nantes University Hospital | Rapid Sequence Induction | 03/27 | 04/27 | | |
