| Mallon, Patrick |
| Completed | 3 | 447 | Europe | Biktarvy, Symtuza | NEAT ID Foundation, Gilead Sciences, Janssen Pharmaceuticals | HIV/AIDS | 06/24 | 06/24 | | |
| Recruiting | N/A | 10000 | Europe | | University College Dublin, Beaumont Hospital, Children's Health Ireland, Cork University Hospital, Mater Misericordiae University Hospital, Our Lady of Lourdes Hospital, Drogheda, St. James's Hospital, Ireland, St. Luke's Hospital, Ireland, St Vincent's University Hospital, Ireland, Wexford General Hospital | Infectious Disease | 12/24 | 12/24 | | |
| Active, not recruiting | N/A | 8894 | Europe, RoW | COVID-19 vaccination | University of Bologna, Universita di Verona, Hospital Universitario Virgen Macarena, Azienda Ospedaliera di Padova, Azienda Ospedaliero-Universitaria di Parma, Azienda Ulss 2 Marca Trevigiana, University College Dublin, Luxembourg Institute of Health, ICONA Foundation, University Medical Center Groningen, University of Buenos Aires, PENTA Foundation, Universiteit Antwerpen, Institut National de la Santé Et de la Recherche Médicale, France, Helmholtz Zentrum München, CINECA consorzio universitario italiano, Charite University, Berlin, Germany, Centre de Recherche Médicale de Lambaréné | SARS CoV 2 Infection, Vaccination; Infection, Breakthrough Infection | 07/23 | 11/24 | | |
| Brennan, Lorraine |
| Active, not recruiting | N/A | 192 | Europe, RoW | Research activities, Do-it-yourself devices, filling out online-questionnaires, sample collection with supplied kits | TNO, University of Eastern Finland, Lund University, NIHS, University of Barcelona, University College Dublin, Newcastle University, Technical University Munchen, Universitaire Ziekenhuizen Leuven, University of Oslo, University of Copenhagen, University of Graz, Tufts University, Charles University, Czech Republic, NuGo, VITAS Analytical Services, Humboldt-Universität zu Berlin, CSIRO Animal, Food and Health Sciences, SwissAnalysis AG, Agroscope Liebefeld-Posieux Research Station ALP, CRA NUT - Centro di Ricerca per gli Alimenti e la Nutrizione | Nutritional Physiological Phenomena, Health, Biological Markers | 01/25 | 01/25 | | |
NCT06749327: Dissecting the Roles of High-quality Diets and Ultra Processed Foods on Cardiometabolic Health |
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| Not yet recruiting | N/A | 330 | Europe | High UPF, high hPDI diet, Low UPF, high hPDI diet | Queen's University, Belfast, University College Dublin, Harvard School of Public Health (HSPH) | Cardiometabolic Risk Factors | 03/27 | 03/29 | | |
| Gibney, Eileen |
NCT06631469: Behaviour-focused Personalised Nutrition Intervention |
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| Recruiting | N/A | 40 | Europe | Personalised behavioural sustainable and healthy dietary recommendations, Personalised sustainable and healthy dietary recommendations | University College Dublin, PLAN'EAT Consortium (https://planeat-project.eu/) | Dietary Behaviours, Sustainable Healthy Diet, Personalised Nutrition | 03/25 | 03/25 | | |
| Recruiting | N/A | 200 | Europe | Fortified Bread, Unfortified bread | University College Cork, University College Dublin | Vitamin D Deficiency | 03/25 | 03/25 | | |
| Roux, Carel W Le |
| Completed | N/A | 34 | Europe | Food Preference | Imperial College London | Obesity | 09/21 | 09/21 | | |
NCT05324241: Laxative Properties of Microencapsulated Lipid (Constipation Study) |
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| Recruiting | N/A | 31 | Europe | Fat Microcapsules | University College Dublin | Constipation | 04/23 | 04/23 | | |
| Recruiting | N/A | 64 | Europe | oesophagectomy | University College Dublin | Oesophageal Cancer | 06/23 | 06/23 | | |
NCT06135935: Postprandial Glucose Response Using Mass-Market No-Added-Sugar Ice Cream |
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| Recruiting | N/A | 12 | RoW | No-added-sugar ice cream, Conventional products | Dasman Diabetes Institute | Type 2 Diabetes | 12/23 | 01/24 | | |
| Recruiting | N/A | 13 | RoW | α-MSH infusion, Placebo solutions | Dasman Diabetes Institute | Type 2 Diabetes Mellitus | 04/24 | 04/24 | | |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
NCT04595968: Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus |
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| Completed | N/A | 267 | Europe, US | Vestal DM Active device, Lifestyle modification, Vestal DM Sham device | Neurovalens Ltd., University College Dublin, CS Lifescience, Clinical Trial Mentors | Type 2 Diabetes | 08/24 | 08/24 | | |
VOYAGER, NCT06710587: Does Use of the Voy Program Improve Weight Loss Percentage and Other Health Outcomes in a Population Already Taking GLP/GIP-1RA Medication? |
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| Not yet recruiting | N/A | 470 | NA | Voy Program | Menwell Limited, Lindus Health | Obesity, Weight Loss | 04/26 | 04/27 | | |
| Recruiting | N/A | 150 | Europe | Bariatric surgery + goal directed medical therapy, Bariatric surgery | Imperial College London | Obesity, Type 2 Diabetes | 04/27 | 08/27 | | |
| Yanai, Henit |
NCT03500653: Curcumin Supplementation as an Add on Treatment for Patients With Inflammatory Bowel Diseases Treated With Vedolizumab |
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| Recruiting | N/A | 100 | RoW | Curcumin, Placebo | Henit Yanai, Shaare Zedek Medical Center | Inflammatory Bowel Diseases | 12/21 | 12/22 | | |
| Recruiting | N/A | 225 | Europe, Canada, RoW | Colonoscopy, Intestinal biopsies, Confocal laser endomicroscopy, Intestinal ultrasound, Stool, Blood, Saliva, Clinical follow-up | University College Cork, The Leona M. and Harry B. Helmsley Charitable Trust | Crohn Disease | 10/25 | 05/26 | | |
| Not yet recruiting | N/A | 2500 | RoW | | Tel-Aviv Sourasky Medical Center | Inflammatory Bowel Disease | 12/26 | 12/26 | | |
| Smith, Cameron R |
| Enrolling by invitation | 4 | 40 | US | Ropivacaine, Naropin, Sham Comparator, Control | University of Florida | Mouth Abnormalities, Cleft Palate, Birth Defect | 10/25 | 10/25 | | |
DIAGNODE-3, NCT05018585 / 2021-002731-32: A Phase III Study to Investigate If the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed with Type 1 Diabetes |
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| Recruiting | 3 | 330 | Europe, US, RoW | Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Diamyd, Colecalciferol 2000 IU, Divisun 2000 IU, Placebo | Diamyd Medical AB | Type 1 Diabetes Mellitus | 12/27 | 12/27 | | |
| Active, not recruiting | 2 | 26 | Europe, US | SPI-62, Placebo | Sparrow Pharmaceuticals, Sparrow Pharmaceuticals, Inc. | Cushing's Syndrome I, Cushing Disease Due to Increased ACTH Secretion, Cortisol Excess, Cortisol; Hypersecretion, Cortisol Overproduction, Ectopic ACTH Secretion | 12/24 | 12/25 | | |
| Active, not recruiting | 2 | 30 | Europe, US | SPI-62 dose | Sparrow Pharmaceuticals, Sparrow Pharmaceuticals, Inc. | Autonomous Cortisol Secretion (ACS), ACTH-Independent Cushing Syndrome, ACTH-Independent Adrenal Cushing Syndrome, Somatic | 12/24 | 12/25 | | |
| Recruiting | 1/2 | 80 | US | Bupivacaine or Ropivacaine with epinephrine plus dexamethasone - Group 1, Bupivacaine or Ropivacaine with epinephrine plus dexamethasone - Group 2 | University of Florida | Chronic Rhinosinusitis (Diagnosis) | 12/25 | 12/26 | | |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
NCT03310528: Gastric Ultrasound for Estimation of the Aspiration Risk Study |
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| Recruiting | N/A | 200 | US | Interview questionnaire, Gastric ultrasound exam | University of Florida | Respiratory Aspiration of Gastric Contents | 07/25 | 07/26 | | |
LINC6, NCT05382156: Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome |
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| Active, not recruiting | N/A | 206 | Europe, US | Osilodrostat, Isturisa | RECORDATI GROUP | Endogenous Cushing's Syndrome | 06/27 | 08/27 | | |
| Silverstein, Julie M |
| Active, not recruiting | 2 | 26 | Europe, US | SPI-62, Placebo | Sparrow Pharmaceuticals, Sparrow Pharmaceuticals, Inc. | Cushing's Syndrome I, Cushing Disease Due to Increased ACTH Secretion, Cortisol Excess, Cortisol; Hypersecretion, Cortisol Overproduction, Ectopic ACTH Secretion | 12/24 | 12/25 | | |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Completed | N/A | 300 | US | Fluid Restricted Group | Washington University School of Medicine | Hyponatremia, Hyponatremic, Pituitary Tumor, Pituitary, Surgery | 07/24 | 07/24 | | |
LINC6, NCT05382156: Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome |
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| Active, not recruiting | N/A | 206 | Europe, US | Osilodrostat, Isturisa | RECORDATI GROUP | Endogenous Cushing's Syndrome | 06/27 | 08/27 | | |
| Brennan, Donal |
| Recruiting | 3 | 538 | Europe, US | cisplatin | The Netherlands Cancer Institute | Ovarian Cancer | 04/25 | 04/26 | | |
COMFORT, NCT05518591: COMpassion FOcused Therapy and Breathing Pattern REtraining After Cancer Recurrence |
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| Recruiting | N/A | 160 | Europe | Compassion Focused Therapy (CFT) combined with Breathing Pattern Retraining (BPR) | University College Dublin, Mater Misericordiae University Hospital, Irish Cancer Society | Psychological Distress, Cancer Recurrence | 03/23 | 06/23 | | |
| Not yet recruiting | N/A | 308 | Europe | Digital Cognitive Behavioural Therapy for Insomnia (dCBT-I), Sleep Hygiene Education (SHE) | University College Dublin, Irish Cancer Society, Big Health Ltd., Research Electronic Data Capture (REDCap) | Insomnia, Cancer | 06/24 | 06/24 | | |
| Lennon, Olive |
| Recruiting | N/A | 40 | Europe | Ekoskeleton (Intervention), Ekso NR, Relaxation (Comparator) | University College Dublin, Royal College of Surgeons, Ireland, University of Aarhus | Traumatic Spinal Cord Injury | 02/26 | 11/26 | | |
| Casella, Giovanni |
| Recruiting | 4 | 120 | Europe, Canada, US, RoW | Metabolic surgery, Bariatric surgery, Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Incretin-Based Therapy, Glucagon-like Peptide-1 Receptor Agonist | Ali Aminian | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis, Obesity | 05/29 | 12/29 | | |
| O'Sullivan, Aifric |
SuHeGuide, NCT05253547: Dietary Intervention Study on Food Based Dietary Guidelines for Sustainable and Healthy Lifestyles |
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| Completed | N/A | 355 | Europe | Healthy climate-friendly dietary guidelines, Healthy dietary guidelines | University College Dublin, Teagasc, University College Cork, Queen's University, Belfast | Dietary Habits, Healthy Diet, Healthy Nutrition, Personalized Nutrition | 06/23 | 06/23 | | |
| Recruiting | N/A | 200 | Europe | Fortified Bread, Unfortified bread | University College Cork, University College Dublin | Vitamin D Deficiency | 03/25 | 03/25 | | |
NCT05924633: A Study of a Dietary Supplement in Breastfeeding Mothers (WellFed) |
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| Completed | N/A | 57 | Europe | Supplement containing a protein hydrolysate + beta glucan (Wellmune®), Placebo supplement containing maltodextron | University College Dublin | Dietary Habits, Dietary Supplements, Maternal Health, Breastfeeding, Infant Health | 08/24 | 08/24 | | |
| Rowell, Jennifer |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Manessis, Anastasios |
TRANSCEND-T2D-2, NCT06260722: Effect of Retatrutide Compared with Semaglutide in Adult Participants with Type 2 Diabetes and Inadequate Glycemic Control with Metformin with or Without SGLT2 Inhibitor |
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| Recruiting | 3 | 1250 | Canada, US, RoW | Retatrutide, LY3437943, Semaglutide | Eli Lilly and Company | Diabetes Mellitus, Type 2 | 12/26 | 03/27 | | |
NCT06297603: Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3) |
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| Recruiting | 3 | 320 | Europe, US, RoW | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Type 2 Diabetes | 09/26 | 10/26 | | |
QWINT-5, NCT05463744: A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy |
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| Completed | 3 | 692 | Europe, Japan, US, RoW | Insulin Efsitora Alfa, LY3209590 and Basal Insulin-FC, Insulin Degludec | Eli Lilly and Company | Type 1 Diabetes, Diabetes | 05/24 | 05/24 | | |
| Recruiting | 3 | 405 | Europe, Canada, US, RoW | Plozasiran Injection, ARO-APOC3, Placebo | Arrowhead Pharmaceuticals | Severe Hypertriglyceridemia | 07/26 | 10/26 | | |
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk |
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| Active, not recruiting | 3 | 2749 | Europe, US, RoW | Orforglipron, LY3502970, Insulin Glargine | Eli Lilly and Company | Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease | 09/25 | 01/26 | | |
ATTAIN-2, NCT05872620: A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes |
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| Active, not recruiting | 3 | 1500 | Europe, US, RoW | Orforglipron, LY3502970, Placebo | Eli Lilly and Company | Obesity, Overweight, Type 2 Diabetes | 08/25 | 08/25 | | |
NCT05238142: In-Home Study with MiniMed™ 780G Pump Automated Control in Type 2-Evaluation of the AHCL System in Adults with Insulin-requiring Type 2 Diabetes |
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| Active, not recruiting | N/A | 575 | US | MiniMed™ 780G Insulin Pump system | Medtronic Diabetes | Type 2 Diabetes Treated with Insulin | 01/25 | 02/25 | | |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Recruiting | N/A | 925 | US | Blood glucose meter, Eversense CGM System | Senseonics, Inc. | Diabetes | 03/26 | 03/26 | | |
| Mahon, Ciara |
P-VECT, NCT04181749: Peri-vascular Adipose Tissue Inflammation Evaluated Using Coronary CT Angiography |
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| Recruiting | 2 | 200 | Europe | aspirin and atorvastatin | University of Leicester, University of Oxford, British Heart Foundation, National Institute for Health Research, United Kingdom | Cardiovascular Risk Factor | 01/24 | 01/24 | | |
NCT06076993: Cluster Randomised Control Trial of the BodyKind Body Image Programme |
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| Recruiting | 1/2 | 600 | Europe | BodyKind programme | University College Dublin, Jigsaw, The National Centre for Youth Mental Health, Ireland, Irish Research Council, Be Real USA NFP | Body Image | 06/24 | 06/24 | | |
| Srinath, Reshmi |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
NCT04595968: Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus |
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| Completed | N/A | 267 | Europe, US | Vestal DM Active device, Lifestyle modification, Vestal DM Sham device | Neurovalens Ltd., University College Dublin, CS Lifescience, Clinical Trial Mentors | Type 2 Diabetes | 08/24 | 08/24 | | |
| Menezes, Camilo |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Clancy, Aoife |
NCT05061381: Effectiveness of a School Wellbeing Programme for Internalising Problems in Irish Primary School Children |
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| Active, not recruiting | N/A | 400 | Europe | A Lust for Life Schools Programme | University College Dublin | Anxiety, Low Mood | 07/22 | 11/22 | | |
| Treacy, Teresa |
| Not yet recruiting | N/A | 308 | Europe | Digital Cognitive Behavioural Therapy for Insomnia (dCBT-I), Sleep Hygiene Education (SHE) | University College Dublin, Irish Cancer Society, Big Health Ltd., Research Electronic Data Capture (REDCap) | Insomnia, Cancer | 06/24 | 06/24 | | |
| Faria, Luccas de |
NCT05871060: Effect of a Novel Protein Supplement on Appetite in Older Adults |
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| Completed | N/A | 14 | Europe | Whey Protein Concentrate, Placebo, Whey hydrolysate | University College Dublin, FHI 360 | Aging, Appetite Loss | 09/23 | 10/23 | | |
| Carr, Alan |
NCT06135766: Evaluating the Effectiveness of a School-based Intervention to Improve the Wellbeing of Children Aged 10 to 13 Years. |
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| Recruiting | N/A | 300 | Europe | A Lust for Life, Waiting List Control | University College Dublin | Well-Being, Psychological, Child, Only | 06/24 | 06/24 | | |
NCT06135779: Evaluation of the Effectiveness of a School-based Intervention to Improve the Wellbeing of Children Aged 8-11 Years. |
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| Recruiting | N/A | 300 | Europe | A Lust for Life, Waiting List Control | University College Dublin | Well-Being, Psychological, Child, Only | 06/24 | 06/24 | | |
| Mejia, Kimberyly Valle |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Heneghan, Helen |
| Recruiting | 4 | 120 | Europe, Canada, US, RoW | Metabolic surgery, Bariatric surgery, Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Incretin-Based Therapy, Glucagon-like Peptide-1 Receptor Agonist | Ali Aminian | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis, Obesity | 05/29 | 12/29 | | |
| Recruiting | N/A | 200 | Europe | Negative Pressure Wound Therapy | Royal College of Surgeons, Ireland | Pilonidal Sinus, Wound Healing | 10/26 | 04/27 | | |
| Diocareza, Anna |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Roa, Hector |
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes |
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| Suspended | N/A | 320 | Europe, US | Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham) | Fractyl Health Inc. | Type 2 Diabetes | 06/25 | 01/26 | | |
| Brennan, ssor Lorraine |
NCT06749327: Dissecting the Roles of High-quality Diets and Ultra Processed Foods on Cardiometabolic Health |
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| Not yet recruiting | N/A | 330 | Europe | High UPF, high hPDI diet, Low UPF, high hPDI diet | Queen's University, Belfast, University College Dublin, Harvard School of Public Health (HSPH) | Cardiometabolic Risk Factors | 03/27 | 03/29 | | |
