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12 Active 2 Inactive 14 All	Not yet recruiting Recruiting Enrolling by invitation Active, not recruiting Available No longer recruiting	Industry lead sponsor Industry collaborator Coop Other	US Canada Japan Europe RoW	N/A 1 2 3 4	Highlight changes:- Show only changed items Enrollment:

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7 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Nef, Holger
TriCLASP, NCT04614402: Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System	Active, not recruiting	N/A	300	Europe	Edwards PASCAL Transcatheter Valve Repair System, Edwards PASCAL Precision Transcatheter Valve Repair System	Edwards Lifesciences	Tricuspid Valve Insufficiency	04/23	03/28
REDUCELAPHFIII, NCT03191656: REDUCE LAP-HF III Corvia Protocol 1701	Recruiting	N/A	500	Europe	IASD Implant	Corvia Medical	Heart Failure	07/26	07/28
NCT06181240: Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)	Recruiting	N/A	400	Europe	Intravascular lithotripsy	Bolt Medical	Coronary Artery Disease, Coronary Artery Calcification	04/25	03/26
NCT02710435: REDUCER-I: An Observational Study of the Neovasc Reducer™ System	Active, not recruiting	N/A	400	Europe	Reducer System, Reducer	Neovasc Inc., Shockwave Medical, Inc.	Angina Pectoris, Angina Pectoris, Stable, Chronic Stable Angina	11/23	12/28
MiCLASP, NCT04430075: Post Market Clinical Follow-Up (PMCF) Study	Recruiting	N/A	1000	Europe	Edwards PASCAL Transcatheter Valve Repair System and Edwards PASCAL Precision Transcatheter Valve Repair System	Edwards Lifesciences	Mitral Regurgitation, Mitral Insufficiency	12/25	03/31
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial	Recruiting	N/A	1247	Europe, Canada, US	Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System	Edwards Lifesciences	Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation	01/25	04/30
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function	Recruiting	N/A	1252	Europe, Canada, US	Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump	Abiomed Inc.	Left Ventricular Dysfunction, Coronary Artery Disease	03/26	10/27