Universite de Sherbrooke
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 15 Trials 
18 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Jerath, Angela
CODEX, NCT04289142: Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Recruiting
4
2400
Canada
Dexmedetomidine Hydrochloride Group, Dexmedetomidine Hydrochloride
Sunnybrook Health Sciences Centre, London Health Sciences Centre, University Health Network, Toronto, McMaster University
Delirium, Cognitive Dysfunction, Cognition Disorder, Neurocognitive Disorders, Mental Disorders, Confusion, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Signs and Symptoms, Dexmedetomidine, Hypnotics and Sedatives, Central Nervous System Depressants, Physiological Effects of Drugs, Analgesics, Non-Narcotic, Analgesics, Molecular Mechanisms of Pharmacological Action
03/26
03/26
SAVE-ICU, NCT04415060: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival

Recruiting
3
800
Canada
Isoflurane Inhalant Product, Sevoflurane inhalant product
Sunnybrook Health Sciences Centre
Covid19, Hypoxic Respiratory Failure
03/26
06/27
ABOVE, NCT05867472: Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents

Recruiting
3
60
Canada
Isoflurane Inhalant Product, Sevoflurane inhalant product
Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR)
Intensive Care Units, Pediatric, Anesthetics, Inhalation
05/26
05/26
TXA-Dosing, NCT05075200: Tranexamic Acid Dosing for Major Joint Replacement Surgery

Active, not recruiting
2
21
Canada
Tranexamic acid, CYKLOKAPRON, trans-4 (aminomethyl) cyclohexanecarboxylic acid
Sunnybrook Health Sciences Centre
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
08/24
08/24
LUSvsCXR, NCT06022081: Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax

Active, not recruiting
N/A
60
Canada
Lung ultrasound to detect pneumothorax.
Sunnybrook Health Sciences Centre
Pneumothorax
03/25
09/25
Lamontagne, Francois
SNAP, NCT05137119: Staphylococcus Aureus Network Adaptive Platform Trial

Recruiting
4
8000
Europe, Canada, RoW
Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging
University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute
Staphylococcus Aureus Bacteremia
12/28
12/28
ARBs CORONA II, NCT04606563: Host Response Mediators in Coronavirus (COVID-19) Infection - Is There a Protective Effect of Losartan and Other ARBs on Outcomes of Coronavirus Infection?

Terminated
3
341
Europe, Canada
Losartan, Cozaar, Valsartan, Diovan, Azilsartan, Edarbi, Candesartan, Atacand, Eprosartan, Teventen, Irbesartan, Avapro, Olmesartan, Olmetec, Telmisartan, Micardis
University of British Columbia, Canadian Institutes of Health Research (CIHR)
Covid19, SARS-CoV Infection
04/22
04/22
REVISE, NCT03374800 / 2020-000483-27: Re-EValuating the Inhibition of Stress Erosions () Trial

Completed
3
4800
Europe, Canada, US, RoW
Placebo (0.9% saline), normal saline; NaCl 0.9%, Pantoprazole, Protonix
McMaster University, Canadian Institutes of Health Research (CIHR), Canadian Critical Care Trials Group, Australian and New Zealand Intensive Care Society Clinical Trials Group, National Health and Medical Research Council, Australia
Gastrointestinal Hemorrhage (Clinically Important, Upper)
10/23
01/24
CATCO, NCT04330690: Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

Active, not recruiting
3
2900
Canada
Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide
Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc.
COVID-19
03/24
05/24
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
ATTACC-CAP, NCT05848713: AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

Recruiting
3
4000
Canada, US, RoW
Heparin
University of Manitoba, Canadian Institutes of Health Research (CIHR), Research Manitoba, Ozmosis Research Inc., Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, Canadian Critical Care Trials Group, AVANTI
Community-acquired Pneumonia
03/28
03/29
CEPEC, NCT06605144: Canadian Critical Care Comparative Effectiveness Platform

Not yet recruiting
N/A
6500
NA
1- Vasopressors - Mean arterial pressure 55-59, 2- Vasopressors - Mean arterial pressure 60-65, 3- Vasopressors - Mean arterial pressure 66-69, 4- Vasopressors - Mean arterial pressure 70-75
Université de Sherbrooke
Intensive Care Unit ICU
12/29
06/30
ARBS CORONA I, NCT04510623: Host Response Mediators in Coronavirus (COVID-19) Infection

Recruiting
N/A
500
Canada
ARBs and/or ACE inhibitors, Usual Care
University of British Columbia, Canadian Institutes of Health Research (CIHR), British Columbia Centre for Disease Control, McGill University Health Centre/Research Institute of the McGill University Health Centre, University of Toronto, University of Ottawa, University of Calgary, University of Alberta, University of Victoria, Wuhan University, Peking Union Medical College, University of Pennsylvania
COVID-19, SARS-CoV2
06/21
06/22
Gendron, Louis
DNIC, NCT03376867: Reference Values and Clinical Screening Test of Diffuse Noxious Inhibitory Controls

Active, not recruiting
N/A
468
Canada
Conditioned pain modulation, Pressure points
Université de Sherbrooke, Canadian Institutes of Health Research (CIHR), Centre for Research of CHUS (CRCHUS), CIHR/SPOR - chronic pain network
Chronic Pain
02/22
12/24
Tetu, Amelie
NCT04559217: 68Ga-DOTATATE Neuroblastoma Imaging Pilot

Recruiting
2
20
Canada
Radiopharmaceutical 68Ga-DOTATATE
Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Neuroblastoma
12/26
09/27
NCT05974579: Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated with Amyotrophic Lateral Sclerosis

Active, not recruiting
1
12
Canada
89Zr-DFO-AP-101
Université de Sherbrooke, Eli Lilly and Company, Chorus Wellness Inc.
Amyotrophic Lateral Sclerosis
12/24
03/25
Carbonneau, Elaine
SAVE-ICU, NCT04415060: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival

Recruiting
3
800
Canada
Isoflurane Inhalant Product, Sevoflurane inhalant product
Sunnybrook Health Sciences Centre
Covid19, Hypoxic Respiratory Failure
03/26
06/27
D'Aragon, Frederick
SAVE-ICU, NCT04415060: SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival

Recruiting
3
800
Canada
Isoflurane Inhalant Product, Sevoflurane inhalant product
Sunnybrook Health Sciences Centre
Covid19, Hypoxic Respiratory Failure
03/26
06/27
Moreau, Francois
No trials found

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