Torrance Memorial Physician Network - TRIO
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 55 Trials 
94 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Chan, David
REACH, NCT03956368: Efficacy of Atorvastatin in Chronic Subdural Haematoma

Recruiting
3
690
RoW
Atorvastatin 20mg, Placebos
Chinese University of Hong Kong
Chronic Subdural Hematoma
09/22
03/23
ZIRCON, NCT03849118 / 2018-002773-21: 89Zr-TLX250 for PET/CT Imaging of ccRCC- Study

Completed
3
300
Europe, Canada, US, RoW
89Zr-girentuximab, 89Zr-TLX250, 89Zr-DFO-TFP-girentuximab (GTX)
Telix Pharmaceuticals (Innovations) Pty Limited, Telix International Pty Ltd
Clear Cell Renal Cell Carcinoma
10/22
11/22
postMONARCH, NCT05169567 / 2021-002301-10: Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer

Active, not recruiting
3
368
Europe, US, RoW
Abemaciclib, Fulvestrant, Placebo
Eli Lilly and Company, Eli Lilly and Company
Breast Neoplasm, Neoplasm Metastasis
02/24
02/26
COMPOSE, NCT04919226 / 2021-001086-20: Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) -

Recruiting
3
250
Europe, US, RoW
177Lu-Edotreotide (Peptide Receptor Radionuclide Therapy) PRRT, 177Lu-DOTATOC 177Lu-Edo, CAPTEM (Capecitabine and Temozolomide), Amino-Acid Solution, Arginine-Lysine Solution, Everolimus, FOLFOX (Folinic acid + Fluorouracil + Oxaliplatin)
ITM Solucin GmbH
Neuroendocrine Tumors
06/27
09/27
FLAMINGO-01, NCT05232916: Phase 3 Study to Evaluate the Efficacy and Safety of HER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects

Recruiting
3
750
Europe, US
Placebo, GLSI-100
Greenwich LifeSciences, Inc.
Breast Cancer
12/26
12/26
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Recruiting
3
6000
Europe, Canada, Japan, US, RoW
Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane
Eli Lilly and Company
Breast Neoplasms
10/27
03/32
NCT04438304: A Diagnostic Imaging Study of 64Cu-SARTATE Using PET on Patients With Known or Suspected Neuroendocrine Tumors (DISCO)

Active, not recruiting
2
63
RoW
64Cu-SARTATE, 64Cu-MeCOSar-Octreotate
Clarity Pharmaceuticals Ltd
Neuroendocrine Tumors
10/24
10/24
NCT04798781: Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma

Active, not recruiting
2
16
US
Telatinib, Keytruda, pembrolizumab
Andrew Hendifar, MD, EOC Pharma
Gastric Cancer, Hepatocellular Carcinoma
02/24
02/25
NCT06445114: Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

Not yet recruiting
2
50
US
Cisplatin, Chemoradiation
Zachary Zumsteg
Oropharyngeal Cancer, Carcinoma
03/32
03/32
TRIO-US B-12 TALENT, NCT04553770: Trastuzumab Deruxtecan Alone or in Combination with Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Checkmark Presentation of data from TALENT trial for HER2 Low, HR+ breast cancer at SABCS 2022
Dec 2022 - Dec 2022: Presentation of data from TALENT trial for HER2 Low, HR+ breast cancer at SABCS 2022
Recruiting
2
88
US
Anastrozole, Anastrazole, Arimidex, ICI D1033, ICI-D1033, ZD-1033, Therapeutic Conventional Surgery, Trastuzumab Deruxtecan, DS-8201, DS-8201a, Enhertu, Fam-trastuzumab Deruxtecan-nxki, WHO 10516
Jonsson Comprehensive Cancer Center, Translational Research in Oncology-U.S, Daiichi Sankyo Co., Ltd.
Early-stage Breast Cancer, Hormone Receptor Positive Breast Carcinoma, Invasive Breast Cancer, Stage II Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
09/25
09/25
NCT06123286: Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms

Not yet recruiting
1
30
US
Tart Cherry, Omega 3 FA (Fish Oil)
Philip Chang, The Cherry Marketing Institute
Breast Cancer, Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Joint Pain
01/27
01/27
PMCH, NCT03615053: Personalized Medicine for Canadians With Hemophilia

Recruiting
N/A
600
Canada
Implementation of WAPPS-Hemo personalized dosing regimen
McMaster University
Hemophilia A, Hemophilia B
09/22
09/23
NCT05143216: High Concentration Oxygen Therapy for Pneumocephalus in Chronic Subdural Haematoma: A Prospective Observational Study

Recruiting
N/A
23
RoW
Low concentration oxygen group: Room air (0-2Litre Oxygen via Nasal Canula), High concentration oxygen group: Room air (12-15Litre Oxygen via Non-rebreather Mask)
Dr. David Yuen Chung CHAN
Chronic Subdural Hematoma
12/22
12/23
HOPE, NCT04725851: High Concentration Oxygen for Pneumocephalus After Evacuation of Chronic Subdural Haematoma

Recruiting
N/A
36
RoW
High concentration Oxygen therapy, Control: Room Air or Low concentration Oxygen
Chinese University of Hong Kong
Chronic Subdural Hematoma, Recurrence, Oxycephaly
12/23
12/24
NCT04403802: Voxx Human Performance Technology Socks for Chemotherapy-Induced Peripheral Neuropathy

Completed
N/A
28
US
Voxx Human Performance Technology Socks, Placebo Socks
Arash Asher, MD, VoxxLife
Neuropathy;Peripheral, Chemotherapy-induced Peripheral Neuropathy, Neuropathy
05/24
05/24
ACTRN12618001819213: A novel PET (positron emission tomography) tracer for donut-like PET findings in patients with neuroendocrine tumours

Recruiting
N/A
10
 
Northern Sydney Local Health District, Sydney Vital
Neuroendocrine tumours
 
 
Yang, Jin Mo
RC48-C012, NCT04400695: A Study of RC48-ADC for the Treatment of Locally Advanced or Metastatic Breast Cancer With Low Expression of HER2

Recruiting
3
366
RoW
RC48-ADC, RC48, Paclitaxel Injection, Taxol, Docetaxel Injection, Taxotere, Vinorelbine Tartrate Injection, Navelbine, Capecitabine Tablets, Xeloda
RemeGen Co., Ltd.
Breast Cancer
06/24
12/24
NCT05188989: Efficacy and Safety Study of TPN171H Tablets in Erectile Dysfunction.

Completed
3
765
RoW
TPN171H 2.5mg group, Simmerafil, TPN171H 5mg group, TPN171H 10mg group, Placebo group
Vigonvita Life Sciences
Erectile Dysfunction
02/23
02/23
HER2CLIMB-02, NCT03975647 / 2019-005017-39: A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

Jan 2024 - Dec 2024: From HER2CLIMB-02 trial for breast cancer
Hourglass Jan 2022 - Dec 2022 : Completion of enrollment of HER2CLIMB-02 trial in combination with Kadcyla for breast cancer
Active, not recruiting
3
466
Europe, Canada, Japan, US, RoW
tucatinib, ONT-380, placebo, T-DM1, Kadcyla
Seagen Inc., Seagen Inc., Seattle Genetics, Inc., Seagen Inc
HER2-positive Breast Cancer
06/23
10/27
TORCHLIGHT, NCT04085276: Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment

Active, not recruiting
3
531
RoW
JS001, Nab-Paclitaxel, Placebo
Shanghai Junshi Bioscience Co., Ltd.
Triple-Negative Breast Cancer
12/24
12/25
NCT05429684: Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

Recruiting
3
120
RoW
Trastuzumab, herceptin;Inetetamab, Pertuzumab, Perjeta, Nab paclitaxel, Abraxane, Pyrotinib, SHR-1258, Capecitabine, T-DM1, Trastuzumab Emtansine, Everolimus, RAD001, CDK4/6 inhibitor, Palbociclib;, AI, Letrozole, Anti-PD-1 monoclonal antibody, Sintilimab
First Affiliated Hospital Xi'an Jiaotong University
HER2+ Breast Cancer
02/24
02/24
NCT06301854: Long-term Safety of TPN171H Tablet in Erectile Dysfunction.

Recruiting
3
472
RoW
TPN171H, Simmerafil
Vigonvita Life Sciences
Erectile Dysfunction
04/25
04/25
EMBER-3, NCT04975308 / 2021-000079-35: A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Active, not recruiting
3
866
Europe, Japan, US, RoW
Imlunestrant, LY3484356, Exemestane, Fulvestrant, Abemaciclib, LY2835219
Eli Lilly and Company, Eli Lilly and Company
Breast Neoplasms, Neoplasm Metastasis
06/24
08/27
NCT06419621: PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic Triple-negative Breast Cancer

Recruiting
3
360
RoW
PM8002, Nab-Paclitaxel, Placebo
Biotheus Inc.
Triple Negative Breast Cancer(TNBC)
07/27
07/28
HER2CLIMB-05, NCT05132582 / 2021-002491-39: A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer

Active, not recruiting
3
654
Europe, Canada, Japan, US, RoW
Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo
Seagen Inc., Merck Sharp & Dohme LLC
HER2 Positive Breast Cancer
05/25
10/27
JSKN003-302, NCT06079983: JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects

Not yet recruiting
3
400
RoW
JSKN003, Capecitabine tablets, Gemcitabine hydrochloride for injection, Vinorelbine tartrate injection, Paclitaxel for injection (albumin-bound type), Docetaxel injection, Eribulin mesylate injection
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Breast Cancer
04/25
03/29
FS-1502-III1-01, NCT05755048: FS-1502 Versus T-DM1 for HER2-Positive Unresectable Locally Advanced or Metastatic Breast Cancer

Recruiting
3
314
RoW
Investigational drug: Recombinant Anti-HER2 Humanized Monoclonal Antibody - Monomethyl Auristatin F Conjugates for Injection (FS-1502), Control drug: Trastuzumab emtansine (Kadcyla, T-DM1)
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Breast Cancer
07/25
01/26
BCTOP-L-A01, NCT05891093: Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer

Recruiting
3
766
RoW
Fluzoparib, Anastrozole, Letrozole, Exemestane, Tamoxifen, Toremifene, Abemaciclib, LHRH agonist
Fudan University
Breast Cancer
05/28
05/31
BCTOP-T-A03, NCT05909332: Study of Antivascular Therapy Combined With Chemotherapy Versus Chemotherapy in Adjuvant Therapy of TNBC-BLIS Patients

Recruiting
3
548
RoW
Antivascular therapy, Chemotherapy
Fudan University
Breast Cancer, Triple Negative Breast Cancer
05/29
05/31
OPTIMAL, NCT03315364 / 2020-000954-86: Oral Paclitaxel Trial In Recurrent and Metastatic Breast Cancer As 1st Line Therapy

Active, not recruiting
2/3
549
Europe, RoW
Oral paclitaxel, Liporaxel®, Paclitaxel injection, Taxol®
Daehwa Pharmaceutical Co., Ltd., Daehwa pharmaceutical Co., Ltd.
Recurrent or Metastatic Breast Cancer
02/24
12/25
RC48-C006, NCT03500380: A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases

Active, not recruiting
2/3
301
RoW
RC48-ADC, RC48, Lapatinib, Capecitabine
RemeGen Co., Ltd.
Breast Neoplasms, Breast Diseases, Capecitabine, HER2-positive Breast Cancer, HER2 Positive Breast Carcinoma, HER2-positive Advanced Breast With Liver Metastases
07/24
12/24
NCT05860465: Safety and Efficacy of SPH4336 in Combination With Endocrine Therapy in the Treatment of Locally Advanced or Metastatic Breast Cancer

Recruiting
2/3
254
RoW
SPH4336 Tablets, SPH4336 Tablets Placebo
Shanghai Pharmaceuticals Holding Co., Ltd
Locally Advanced or Metastatic Breast Cancer
03/25
08/25
CATPCC-01, NCT06511726: Induction Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Recruiting
2
29
RoW
Cadonilimab, AK-104
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cervical Cancer
10/25
10/27
NCT05429294: Novel Double Target Therapy Combined With Chemotherapy in First-line Treatment of HER2+ Breast Cancer, MA-BC-II-038

Recruiting
2
209
RoW
Pyrotinib, Trastuzumab, Albumin paclitaxel
First Affiliated Hospital Xi'an Jiaotong University
HER2-positive Breast Cancer
05/24
10/24
TQB2102-II-02, NCT06452706: The Clinical Trial of TQB2102 for Injection Against Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer

Recruiting
2
42
RoW
TQB2102 for injection
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
Breast Cancer
06/26
06/28
TQB3616-II-04, NCT06702618: Evaluation of TQB3616 Capsules in a Phase II Clinical Trial for Recurrent/Metastatic Breast Cancer

Not yet recruiting
2
33
RoW
TQB3616 capsule+Fulvestrant Injection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Breast Cancer
05/26
12/26
NCT05914857: Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients

Not yet recruiting
2
120
RoW
Dapagliflozin 10mg Tab, Dapagliflozin Tablets, lifestyle interventions
Yangjin, Peking University Third Hospital
Prediabetic State, Impaired Fasting Glucose, Impaired Glucose Tolerance
06/25
12/25
TQB2102-Ib-01, NCT06115902: A Study of TQB2102 for Injection in Patients With Recurrent/Metastatic Breast Cancer

Recruiting
1
150
RoW
TQB2102 for injection
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
Breast Cancer
12/25
12/26
NCT05581888: Visual Performance of Functional Intraocular Lenses in Cataracts

Active, not recruiting
N/A
62
RoW
trifocal intraocular lens
Eye & ENT Hospital of Fudan University
High Myopia, Cataract
06/21
03/23
NCT04668703: Prophylactic Effect of Conbercept Intravitreal Injection at the Conclusion of Cataract Surgery for Diabetic Macular Edema

Not yet recruiting
N/A
40
NA
Conbercept intravitreal injection
Eye & ENT Hospital of Fudan University
Diabetic Macular Edema, Diabetic Retinopathy, Cataract Diabetic
11/21
01/22
NCT05530473: Combined Capsular Tension Ring and IOL Implantation for Management of Cataracts

Completed
N/A
200
RoW
capsular tension ring, capsular tension ring (ACPi-11; Bausch&Lomb)
Eye & ENT Hospital of Fudan University, National Natural Science Foundation of China
Intraocular Lens Rotation, Capsular Tension Ring
12/22
03/23
NCT05783063: iTBS for Increased Appetite Induced by Antipsychotics

Recruiting
N/A
60
RoW
Active iTBS, Sham iTBS
Central South University
Schizophrenia
08/25
12/25
NCT05797298: Toric Intraocular Lens (IOL) Implantation for Management of Cataracts

Recruiting
N/A
3000
RoW
Eye & ENT Hospital of Fudan University
Toric Intraocular Lens Stability, Visual Quality
03/24
05/24
NCT06331923: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients with Diabetes

Recruiting
N/A
10168
RoW
Continuous glucose monitoring (CGM) device
Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Wang Jing Hospital, ZhuHai Hospital, Beijing Hospital, Siyang County Hospital of Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, Henan Provincial Chest Hospital, Fuzhou First Hospital, Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Anhui University of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Mindong Hospital of Ningde, The Fifth Hospital of Xiamen, People's Hospital of Ningxia Hui Autonomous Region, The First People's Hospital of Changzhou, The Fifth hospital of Deyang, Suzhou Municipal Hospital, Tang-Du Hospital, Yiyang Central Hospital, First Affiliated Hospital of Xinjiang Medical University, Peng Ding Shan Shi Zhong Yi Yi Yuan, Yueyang Central Hospital, The First People's Hospital of Lianyungang, Haimen District Traditional Chinese Medicine Hospital, The 910th Hospital, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Beijing Tiantan Hospital, Affiliated Hospital of Jiangsu University, Liaocheng People's Hospital, Beijing Chao Yang Hospital, Jilin City Hospital of Chemical Industry, Creen Hospital-465, Wuhan Central Hospital, Air Force Military Medical University, China, Shanghai Tong Ren Hospital, Beijing Anzhen Hospital, Emergency General Hospital, Beijing Tongren Hospital, Civil Aviation General Hospital, Peking University Shougang Hospital, The First Affiliated Hospital of Anhui Medical University, Chinese PLA Central Hospital
Comprehensive Complication Index
10/25
12/25
NCT06719739: Functional IOL Implantation in Patients with Epiretinal Membrane

Recruiting
N/A
90
RoW
Intraocular lens implantation
Eye & ENT Hospital of Fudan University
Cataract, Intraocular Lens Complication, Epiretinal Membrane
09/26
09/26
NCT02182921: Evaluation of Cataract Surgery Outcome

Recruiting
N/A
20000
RoW
Evidence Based Cataract Study Group
Cataract, High Myopia
12/26
12/30
NCT06092164: Visual Outcomes of Functional Intraocular Lenses in Cataracts

Not yet recruiting
N/A
20000
NA
Eye & ENT Hospital of Fudan University
Cataract, Visual Quality
12/29
12/31
COOPERATIONS, NCT05163054: Cohort Study of Patients With Type 1 Diabetes Registered With Mobile Application in China

Not yet recruiting
N/A
500
RoW
Peking University Third Hospital
Type 1 Diabetes
01/32
01/32
NCT05682001: The Molecular Pathogenesis Study of Cataract

Recruiting
N/A
150
RoW
Eye & ENT Hospital of Fudan University, National Natural Science Foundation of China
Cataract, Pathogenesis
12/23
12/25
Zhang, Ying
NCT04612439: Accuracy of VABB Elite 10G Versus BARD 14G CNB

Active, not recruiting
3
1470
RoW
VABB Elite 10G, BARD 14G CNB
Fudan University
Breast Cancer
12/21
06/22
NCT03388593: Survival Study of the Recombinant Human Neuregulin-1β in Subjects With Chronic Heart Failure.

Recruiting
3
1600
RoW
rhNRG-1, Neucardin™, Placebo
Zensun Sci. & Tech. Co., Ltd.
Chronic Heart Failure
02/26
02/26
NCT03236636: The Phase III Study of Icaritin Versus HUACHANSU PIAN in Hepatocellular Carcinoma Subjects

Recruiting
3
312
RoW
Icaritin, SNG-162, HUACHANSU PIAN, HUACHANSU PIAN(999)
Beijing Shenogen Biomedical Co., Ltd, Chinese Academy of Medical Sciences, NanJing PLA 81 Hospital, Peking University Cancer Hospital & Institute, Beijing Hospital, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Jinan Central Hospital, Linyi Tumour Hospital, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, The First Affiliated Hospital with Nanjing Medical University, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China, Nanfang Hospital of Southern Medical University, First People's Hospital of Foshan, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Hebei Medical University Fourth Hospital, The First Hospital of Jilin University, Haikou People's Hospital, Fudan University, West China Hospital, Chongqing Traditional Chinese Medicine Hospital, Chifeng Municipal Hospital, The Affiliated Hospital of Hangzhou Normal University, The First Affiliated Hospital of Zhengzhou University, Guilin Medical University, China, The Third Xiangya Hospital of Central South University, Yunnan Provincial Hospital of Traditional Chinese Medicine, The Sixth People's Hospital of Shenyang
Advanced HBV-Related Hepatocellular Carcinoma (HCC)
12/22
12/22
HER2CLIMB-02, NCT03975647 / 2019-005017-39: A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

Jan 2024 - Dec 2024: From HER2CLIMB-02 trial for breast cancer
Hourglass Jan 2022 - Dec 2022 : Completion of enrollment of HER2CLIMB-02 trial in combination with Kadcyla for breast cancer
Active, not recruiting
3
466
Europe, Canada, Japan, US, RoW
tucatinib, ONT-380, placebo, T-DM1, Kadcyla
Seagen Inc., Seagen Inc., Seattle Genetics, Inc., Seagen Inc
HER2-positive Breast Cancer
06/23
10/27
TQB2102-III-01, NCT06561607: A Clinical Trial to Evaluate the Efficacy and Safety of TQB2102 for Injection Versus Investigator-Selected Chemotherapy in HER2 Low-Expressing Recurrent/Metastatic Breast Cancer

Not yet recruiting
3
542
RoW
TQB2102 for Injection, Chemotherapy drug (Capecitabine/Paclitaxel/Albumin Paclitaxel)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Breast Cancer
01/27
12/28
NCT06696261: A Study of Lianxiaxiaopi Granules in the Treatment of Postprandial Distress Syndrome

Not yet recruiting
3
342
RoW
Lianxiaxiaopi Granules, a simulated agent of Lianxiaxiaopi Granules
Tasly Pharmaceutical Group Co., Ltd
Postprandial Distress Syndrome
06/26
08/26
NCT04263298: Fulvestrant Versus Capecitabine as Maintenance Therapy After First-line Chemotherapy in Patients With HR+/HER2- Metastatic Breast Cancer

Recruiting
3
210
RoW
Fulvestrant, Experimental group, Capecitabine Oral Product, Active Comparator control group
Herui Yao
Metastatic Breast Cancer
05/25
05/30
TSL-TCM-QZKL-Ⅲ, NCT06068478: A Study to Evaluate Efficacy and Safety of Qingzhu Granules in the Treatment of Acute Gouty Arthritis

Recruiting
3
472
RoW
Qingzhu Granules, Qingzhu Granules Placebo
Tasly Pharmaceutical Group Co., Ltd
Gouty Arthritis
10/25
10/25
NCT04651140: Research on the Effect and Mechanism of Aerobic Exercise on PD

Enrolling by invitation
N/A
30
RoW
aerobic exercise
First Hospital of Jilin University
Parkinson's Disease, Physical Exercise
10/21
10/21
IMPACT-NSTEACS, NCT03641898: Intravascular Ultrasound-derived Assessment of Hemodynamically Negative Lesions in NSTEACS Patients

Recruiting
N/A
350
RoW
FFR-guided PCI, Functionally complete revascularization, Intravascular ultrasound
Tianjin Chest Hospital
Non-ST-segment Acute Coronary Syndrome
10/23
10/25
NCT04920214: Application Value of CEUS Li-RADS in Hepatic Focal Lesions in Patients With Non-high Risk Factors for HCC

Recruiting
N/A
500
RoW
SonoVue
Second Affiliated Hospital, School of Medicine, Zhejiang University, Tianjin Third Central Hospital, Sichuan Provincial People's Hospital, Fujian Cancer Hospital, Shandong Jining No.1 People's Hospital, General Hospital of Ningxia Medical University, Beijing Hospital, Red Cross Hospital, Hangzhou, China, Zhejiang Cancer Hospital, Shengjing Hospital
Hepatocellular Carcinoma
12/23
12/23
NCT05782881: High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program

Recruiting
N/A
16000
RoW
phone calls and encouraging patients' lifestyle change and medication adherence, Statin, Angiotensin-converting enzyme inhibitor, Angiotensin receptor neprilysin inhibitor, Glucagon-like peptide-1, Sodium-dependent glucose transporters 2
Wuhan Union Hospital, China, Peking University First Hospital
Cardiovascular Diseases, Diabetes Mellitus, Type 2, Coronary Disease
12/23
12/24
CNAVS, NCT06192238: China National Study of Adrenal Venous Sampling

Not yet recruiting
N/A
1500
RoW
adrenal venous sampling
Chinese Academy of Medical Sciences, Fuwai Hospital
Hyperaldosteronism
12/26
12/26
WML, NCT06608251: Association of Plasma Metabolomic Biomarkers with Chronic Ischemic White Matter Injury

Active, not recruiting
N/A
100
RoW
white matter lesion
Nanjing First Hospital, Nanjing Medical University
Myelinopathy
05/25
05/25
NCT06591078: Evaluation of Clinical Efficacy of Acupuncture in Improving Immune Response in Patients With Cervical Cancer

Not yet recruiting
N/A
90
NA
electropuncture
Ying Zhang, Peking Union Medical College Hospital, Beijing Obstetrics and Gynecology Hospital, Peking University Cancer Hospital & Institute, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Sichuan Cancer Hospital and Research Institute, Shanghai University of Traditional Chinese Medicine, Hunan Cancer Hospital, Chongqing University Cancer Hospital
Cervical Cancer
11/26
11/26
PROCESS, NCT06579677: PRospective Observation on CErebral microvaScular Structure and Function

Recruiting
N/A
3500
RoW
Without any intervention
Beijing Tiantan Hospital, Beijing Daxing District People Hospital
Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases, Cognitive Dysfunction, Cerebrovascular Disorders, Cardiovascular Diseases, Population
03/32
10/32
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM).

Not yet recruiting
N/A
1000
RoW
Continuous Glucose Monitoring System (GX-01S)
Nanjing First Hospital, Nanjing Medical University
Type1 Diabetes Mellitus
10/26
06/27
Sun, Li
NCT04908865: Open-label Study of Belimumab Plus Standard Therapy in Chinese Pediatric Participants With Active Systemic Lupus Erythematosus (SLE)

Active, not recruiting
4
67
RoW
Belimumab, Standard therapy
GlaxoSmithKline
Systemic Lupus Erythematosus
05/24
09/24
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease

Recruiting
4
1312
RoW
GV-971, Placebo
Green Valley (Shanghai) Pharmaceuticals Co., Ltd.
Alzheimer's Disease
06/29
12/29
HER2CLIMB-02, NCT03975647 / 2019-005017-39: A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

Jan 2024 - Dec 2024: From HER2CLIMB-02 trial for breast cancer
Hourglass Jan 2022 - Dec 2022 : Completion of enrollment of HER2CLIMB-02 trial in combination with Kadcyla for breast cancer
Active, not recruiting
3
466
Europe, Canada, Japan, US, RoW
tucatinib, ONT-380, placebo, T-DM1, Kadcyla
Seagen Inc., Seagen Inc., Seattle Genetics, Inc., Seagen Inc
HER2-positive Breast Cancer
06/23
10/27
Symphony2, NCT06353347: Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Active, not recruiting
3
551
RoW
HTD1801, berberine ursodeoxycholate, Placebo
HighTide Biopharma Pty Ltd
Type 2 Diabetes Mellitus
03/25
12/25
NCT06145893: A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease

Recruiting
3
162
RoW
Hemay005, Mufemilast, Phosphodiesterase 4 (PDE4) inhibitors, Placebo
Ganzhou Hemay Pharmaceutical Co., Ltd
Behçet's Disease
11/24
03/25
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer

Active, not recruiting
3
274
RoW
BPI-16350, placebo, Fulvestrant
Betta Pharmaceuticals Co., Ltd.
Breast Cancer
12/23
07/25
SMART, NCT06722586: Sirolimus Monotherapy in the Treatment of Antiphospholipid Antibody Related Thrombocytopenia

Recruiting
3
84
RoW
Sirolimus, Rapamycin, mTOR inhibitor, Placebo
Peking University First Hospital, North China Pharmaceutical Co.,Ltd
Antiphospholipid (aPL)-positive, Thrombocytopaenia
12/27
12/27
SURMOUNT-MMO, NCT05556512: A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

Active, not recruiting
3
15374
Europe, Canada, Japan, US, RoW
Tirzepatide, LY3298176, Placebo
Eli Lilly and Company
Obesity, Overweight
10/27
10/27
TQB2450-II-08, NCT04574284: A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule in Subjects With Advanced Endometrial Cancer

Recruiting
2
196
RoW
TQB2450, Anlotinib
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Advanced Endometrial Cancer
12/21
04/22
NCT04830644: A Study to Evaluate the Efficacy and Safety of Iguratimod Compared to Placebo in Patients With Active Primary Sjogren's Syndrome.

Recruiting
2
144
RoW
Iguratimod, Placebo
Jiangsu Simcere Pharmaceutical Co., Ltd.
Primary Sjögren Syndrome
04/22
06/22
NCT06180889: Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty

Recruiting
2
240
RoW
Enoxaparin, KN060 Low, KN060 Middle, KN060 Hight
Suzhou Alphamab Co., Ltd.
Knee Arthroplasty, Total
12/25
04/26
NCT06250062: A Clinical Study of JS005 in Patients With Ankylosing Spondylitis

Recruiting
2
261
RoW
Recombinant humanized IL-17A Monoclonal Antibody(JS005), Placebo(JS005)
Shanghai Junshi Bioscience Co., Ltd., Sponsor GmbH
Ankylosing Spondylitis
02/25
10/25
NCT06173037: RC88 in Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer

Recruiting
2
88
RoW
RC88, RC88 for Injection
RemeGen Co., Ltd.
Primary Peritoneal Cancer, Fallopian Tube Cancer, Epithelial Ovarian Cancer
06/26
12/26
NCT06241781: Autologous Tumor Infiltrating Lymphocytes (GT101 Injection) in Patients With Recurrent or Metastatic Cervical Cancer

Recruiting
2
64
RoW
GT101 injection, Gemcitabine injection
Grit Biotechnology
Adult
01/27
01/27
NCT06315231: Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients

Recruiting
2
200
RoW
Edaravone dexborneol sublingual tablet, Placebo
Simcere Pharmaceutical Co., Ltd
Post-stroke Cognitive Impairment
12/26
12/26
NCT06251947: Efbemalenograstim Alfa Injection for Ovarian or Cervical Cancer Receiving Chemotherapy Regimen

Recruiting
2
83
RoW
Efbemalenograstim Alfa
Shandong University, Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Ovarian Cancer, Cervical Cancer
06/26
12/26
PALIZADE, NCT05781750: A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis

Suspended
2
279
Europe, US, RoW
zetomipzomib, KZR-616, placebo, matching placebo
Kezar Life Sciences, Inc.
Lupus Nephritis
05/26
07/26
TQB2858-Ⅰ-06, NCT05068921: A Clinical Trial to Evaluate Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignancy

Recruiting
1
40
RoW
TQB2858 injection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Advanced Cervical Cancer
05/23
07/23
NCT06420154: The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Not yet recruiting
1
9
RoW
anti-CD19-CAR-T cells
First Affiliated Hospital of Wenzhou Medical University, Shanghai First Song Therapeutics Co., Ltd
Systemic Lupus Erythematosus (SLE), Sjogren's Syndrome, Systemic Sclerosis, Inflammatory Myopathy, ANCA Associated Vasculitis, Antiphospholipid Syndrome
05/27
05/27
BAT-8006-001-CR, NCT05378737: Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8006 for Injection

Recruiting
1
216
RoW
BAT8006 for Injection, Exatecan conjugate of recombinant humanized monoclonal antibody against folate receptor α for injection
Bio-Thera Solutions
Advanced Solid Tumors
12/24
12/25
NCT05925452: To Evaluate the Efficacy and Safety of Genalumab for Injection in the Treatment of Active Systemic Juvenile Idiopathic Arthritis.

Recruiting
N/A
221
RoW
GenaKumab
Changchun GeneScience Pharmaceutical Co., Ltd.
Active Systemic Juvenile Idiopathic Arthritis
03/28
06/28
NCT03647852: Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura

Recruiting
N/A
150
RoW
Methylprednisolone, IVIG, other basic supportive treatment
Children's Hospital of Fudan University, Shanghai Children's Hospital, Shanghai Children's Medical Center
Henoch-Schönlein Purpura
10/24
10/25
NCT04532541: Monogenic Lupus in Childhood Onset Systemic Lupus Erythematosus

Recruiting
N/A
200
RoW
Monogenic lupus screening
Children's Hospital of Fudan University
Monogenic Lupus, Systemic Lupus Erythematosus
09/25
09/25
COAST, NCT03653156: China Cognition and Aging Study

Recruiting
N/A
100000
RoW
Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital
Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia
01/38
01/38
CFAN, NCT03657732: The Chinese Familial Alzheimer's Network

Recruiting
N/A
40000
RoW
Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital
Alzheimer Disease, Familial Alzheimer Disease (FAD)
01/38
01/38
Marquez, Marina
NCT04502407: Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

Recruiting
2
40
US
Cisplatin-based Radiation Therapy, Cisplatin Chemotherapy
Cedars-Sinai Medical Center
HPV Positive Oropharyngeal Squamous Cell Carcinoma
12/26
12/29
NCT04798781: Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma

Active, not recruiting
2
16
US
Telatinib, Keytruda, pembrolizumab
Andrew Hendifar, MD, EOC Pharma
Gastric Cancer, Hepatocellular Carcinoma
02/24
02/25
NCT03893682: A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Active, not recruiting
1
160
US
CG-806, Luxeptinib
Aptose Biosciences Inc.
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Non-Hodgkin's Lymphoma
12/24
05/25

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