| Terminated | 3 | 141 | US | GM-CSF, Placebo | Nationwide Children's Hospital, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome | 12/24 | 12/24 | | |
| Recruiting | 2/3 | 500 | US | Anakinra, Placebo | Nationwide Children's Hospital, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS) | 05/27 | 08/27 | | |
| Active, not recruiting | N/A | 500 | US | | Children's Hospital of Philadelphia, Akron Children's Hospital, Children's Hospital and Health System Foundation, Wisconsin, Children's Hospital Medical Center, Cincinnati, Children's Mercy Hospital Kansas City, Milton S. Hershey Medical Center, Nationwide Children's Hospital, Nicklaus Children's Hospital, Indiana University, Cooperman Barnabas Medical Center, Baylor College of Medicine, Columbia University, National Heart, Lung, and Blood Institute (NHLBI), Arkansas Children's Hospital Research Institute, Children's Healthcare of Atlanta, Children's Hospital Colorado, Washington University School of Medicine | Acute Respiratory Distress Syndrome | 12/24 | 03/25 | | |