Wang, Zhen Jun |
NCT04834531: Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng) |
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| Not yet recruiting | 4 | 324 | RoW | Zhuli capsule, Placebo, Standard medical treatment | Zhong Wang | Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | 10/23 | 10/23 | | |
BHV3000-318, NCT05371652: A Study to Learn About the Long-term Safety of Rimegepant for the Acute Treatment of Migraine in Chinese Participants |
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| Completed | 3 | 241 | RoW | Rimegepant 75mg Orally Disintegrating Tablets (ODT) | Pfizer, Bioshin (Shanghai) Consulting Services Co., Ltd | Acute Migraine | 02/24 | 02/24 | | |
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel |
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| Completed | 3 | 571 | Europe, Canada, US, RoW | NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel | NovoCure Ltd. | Pancreas Adenocarcinoma | 10/24 | 10/24 | | |
NCT06295432: A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21) |
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| Recruiting | 2 | 90 | RoW | DZD9008+AZD4205, Inapplicable | Dizal Pharmaceuticals | Non-small Cell Lung Cancer | 06/25 | 06/25 | | |
NCT03934567: A Multi-Center Phase 2 Study to Evaluate Efficacy and Safety of Oral Abexinostat as Monotherapy in Patients With Relapsed or Refractory Follicular Lymphoma |
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| Recruiting | 2 | 96 | RoW | Abexinostat | Xynomic Pharmaceuticals, Inc. | Lymphoma, Follicular | 02/24 | 09/24 | | |
NCT03936153: Study to Evaluate Efficacy and Safety of Oral Abexinostat in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) |
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| Recruiting | 2 | 170 | RoW | abexinostat | Xynomic Pharmaceuticals, Inc. | Diffuse Large B-cell Lymphoma (DLBCL) | 12/24 | 05/25 | | |
NCT04539951: Pragmatic Trial of Obsessive-compulsive Disorder |
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| Recruiting | 2 | 1600 | RoW | Sertraline 200 milligram(mg), Sertraline 300 milligram(mg), Fluvoxamine, Venlafaxine, Augment with Memantine, Augment with Aripiprazole | Shanghai Mental Health Center, The first specialized hospital of harbin, Guizhou Provincial People's Hospital, First Affiliated Hospital of Jinan University, West China Hospital, Suzhou Psychiatric Hospital, Nanjing Medical University, Wuhan Mental Health Centre, Seventh People's Hospital of Hangzhou, The First Affiliated Hospital of Kunming Medical College, General Hospital of Ningxia Medical University, The First Affiliated Hospital of Nanchang University, The Second Affiliated Hospital of Xinxiang Medical University | Obsessive-Compulsive Disorder | 06/24 | 12/24 | | |
NCT05956587: A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors |
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| Recruiting | 2 | 121 | RoW | BL-B01D1, SI-B003 | Sichuan Baili Pharmaceutical Co., Ltd., Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. | Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma | 11/25 | 11/25 | | |
NCT04258462: Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors |
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| Recruiting | 2 | 100 | US | Hyperpolarized Carbon C 13 Pyruvate, Hyperpolarized 13C-Pyruvate, Hyperpolarized Pyruvate (13C), Magnetic Resonance Imaging, Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MRI, MRI Scan, Nuclear Magnetic Resonance Imaging, Hyperpolarized 13C,15N2-urea, HP 13C, 15N2 | Zhen Wang, MD, American Cancer Society, Inc., National Cancer Institute (NCI) | Benign Kidney Neoplasm, Kidney Neoplasm, Renal Cell Cancer | 12/26 | 12/26 | | |
| Recruiting | 1/2 | 380 | RoW | PM8002 | Biotheus Inc. | Malignant Neoplasm | 11/25 | 11/25 | | |
NCT04390737: Evaluate the Safety and Clinical Activity of HH2853 |
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| Recruiting | 1/2 | 254 | US, RoW | HH2853 Tablets | Haihe Biopharma Co., Ltd. | FL Lymphoma, Epithelioid Sarcoma, Peripheral T Cell Lymphoma, Advanced Solid Tumor | 12/25 | 12/25 | | |
GFH009X2101, NCT04588922: Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies |
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| Recruiting | 1/2 | 160 | US, RoW | SLS009, GFH009, venetoclax, Venclexta, azacitidine, Vidaza, azacytidine | Sellas Life Sciences Group, Sellas Life Sciences Group | Hematologic Malignancies | 06/25 | 12/25 | | |
NCT06139536: Assessment of Safety, Tolerability and Pharmacokinetics With BAT4706 and BAT1308 in Advanced Solid Tumors Patients |
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| Recruiting | 1 | 210 | RoW | BAT4706 Injection, Fc-glycosylated recombinant fully humanized anti-CTLA-4 monoclonal antibody injection, BAT1308 Injection, Recombinant humanized anti PD-1 monoclonal antibody injection | Bio-Thera Solutions | Advanced Solid Tumor | 12/25 | 02/26 | | |
NCT05982080: A Study to Investigate FP002 in Subjects With Advanced Malignancies |
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| Recruiting | 1 | 27 | RoW | FP002 Injection | Guangdong Fapon Biopharma Inc. | Advanced Solid Tumor | 04/25 | 07/26 | | |
NCT04033484: Pelvic Floor Reconstruction Using Biological Mesh With Negative Pressure Wound Therapy Following ELAPE |
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| Recruiting | N/A | 66 | RoW | Negative Pressure Wound Therapy | Beijing Chao Yang Hospital | Perineal Wound Complications After ELAPE | 07/21 | 07/21 | | |
NCT04039646: ERAS in Patients With Perforated Peptic Ulcer Disease Who Underwent Laparoscopic Repair |
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| Recruiting | N/A | 40 | RoW | ERAS treatment | Beijing Chao Yang Hospital | Hospital Stay, Hospital Cost | 12/21 | 03/22 | | |
LOCAL, NCT03046316: Local Therapy in Advanced NSCLC With Non-progressive Disease (PD) After First Line Therapy |
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| Recruiting | N/A | 60 | RoW | local consolidative treatment | Guangdong Association of Clinical Trials | Lung Neoplasms | 07/22 | 07/26 | | |
NCT04086446: Transcranial Direct Current Stimulation (tDCS) in the Treatment of Drug-naïve Obsessive-compulsive Disorder(OCD) |
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| Recruiting | N/A | 60 | RoW | high-definition transcranial direct current stimulation, Sham tDCS | Shanghai Mental Health Center | Obsessive-Compulsive Disorder | 08/22 | 12/22 | | |
NCT04534504: Sleeve Gastrectomy With Uncut Jejunal Bypass (SG-uncut JJB) Verus Sleeve Gastrectomy in Obese Patients |
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| Recruiting | N/A | 60 | RoW | SG-JJB | Zhen Jun Wang | Excessive Weight Loss, Total Weight Loss, Sleeve Gastrectomy, Jejunojejunal Bypass, Uncut | 08/22 | 08/22 | | |
NCT03649685: Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Obsessive Compulsive Disorder |
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| Recruiting | N/A | 120 | RoW | Continuous theta burst stimulation (cTBS), shame rTMS | Shanghai Mental Health Center, RenJi Hospital, Shanghai 10th People's Hospital | Obsessive-Compulsive Disorder | 12/22 | 04/23 | | |
NCT04527302: Efficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Obsessive-Compulsive Disorder (OCD) |
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| Recruiting | N/A | 60 | RoW | ERP combined with high-definition active tDCS, ERP combined with sham tDCS | Shanghai Mental Health Center | Obsessive-Compulsive Disorder | 06/24 | 08/24 | | |
NCT05445999: A Preliminary Study of Model-driven Individualized Transcranial Electrical Stimulation for Insomnia |
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| Recruiting | N/A | 12 | RoW | High-Definition transcranial electrical stimulation | Shanghai Mental Health Center | Insomnia | 12/24 | 02/25 | | |
NCT04426773: Electroencephalography (EEG) Predictors of Transcranial Direct Current Stimulation (tDCS) in Obsessive-Compulsive Disorder (OCD) |
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| Recruiting | N/A | 30 | RoW | High-Definition transcranial direct current stimulation | Shanghai Mental Health Center | Obsessive-Compulsive Disorder | 04/23 | 12/23 | | |
NCT06085768: A Preliminary Study on the Intervention Effect of Virtual Reality Exposure Therapy on Fear of Flying |
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| Recruiting | N/A | 64 | RoW | VRE intervention | Shanghai Mental Health Center | Fear of Flying, Virtual Reality Exposure Therapy | 11/23 | 11/23 | | |
NCT06105970: Chinese Community Sample of Hierarchical Model of Psychopathology |
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| Recruiting | N/A | 4000 | RoW | No intervention | Shanghai Mental Health Center | Mental Health Issue, Adverse Childhood Experience | 11/23 | 11/27 | | |
NACSOC, NCT02972541: Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer |
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| Recruiting | N/A | 248 | RoW | Stenting with neoadjuvant chemotherapy, Stenting with immediate Surgery | Beijing Chao Yang Hospital | Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction | 12/23 | 12/23 | | |
NACSOC-02, NCT05202314: Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer |
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| Recruiting | N/A | 20 | RoW | Immunotherapy (Camrelizumab), Chemotheray (CAPOX or mFOLFOX6) | Beijing Chao Yang Hospital | Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction, Immunotherapy | 12/23 | 12/26 | | |
| Recruiting | N/A | 66 | RoW | reestablishment of the acute angle of His, sleeve gastrectomy | Zhen Jun Wang | Gastroesophageal Reflux Disease, Excessive Weight Loss, Total Weight Loss, Sleeve Gastrectomy, Angle of His | 12/23 | 12/25 | | |
NCT04534907: The Effect of Immersive Virtual Reality Treatment With Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder |
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| Not yet recruiting | N/A | 30 | RoW | The combination of exposure and response prevention (ERP) and VR, Traditional ERP | Shanghai Mental Health Center | Obsessive-Compulsive Disorder, Virtual Reality | 12/23 | 12/24 | | |
NCT06331923: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients with Diabetes |
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| Recruiting | N/A | 10168 | RoW | Continuous glucose monitoring (CGM) device | Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Wang Jing Hospital, ZhuHai Hospital, Beijing Hospital, Siyang County Hospital of Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, Henan Provincial Chest Hospital, Fuzhou First Hospital, Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Anhui University of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Mindong Hospital of Ningde, The Fifth Hospital of Xiamen, People's Hospital of Ningxia Hui Autonomous Region, The First People's Hospital of Changzhou, The Fifth hospital of Deyang, Suzhou Municipal Hospital, Tang-Du Hospital, Yiyang Central Hospital, First Affiliated Hospital of Xinjiang Medical University, Peng Ding Shan Shi Zhong Yi Yi Yuan, Yueyang Central Hospital, The First People's Hospital of Lianyungang, Haimen District Traditional Chinese Medicine Hospital, The 910th Hospital, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Beijing Tiantan Hospital, Affiliated Hospital of Jiangsu University, Liaocheng People's Hospital, Beijing Chao Yang Hospital, Jilin City Hospital of Chemical Industry, Creen Hospital-465, Wuhan Central Hospital, Air Force Military Medical University, China, Shanghai Tong Ren Hospital, Beijing Anzhen Hospital, Emergency General Hospital, Beijing Tongren Hospital, Civil Aviation General Hospital, Peking University Shougang Hospital, The First Affiliated Hospital of Anhui Medical University, Chinese PLA Central Hospital | Comprehensive Complication Index | 10/25 | 12/25 | | |
NCT06717165: Efficacy and Mechanism of Augmentation of Cognitive Behavioral Therapy with Transcranial Alternating Current Stimulation for Obsessive-Compulsive Disorder (OCD) |
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| Enrolling by invitation | N/A | 120 | RoW | ERP combined with high-definition active tACS, ERP combined with sham tACS | Shanghai Mental Health Center | Obsessive Compulsive Disorder (OCD) | 10/27 | 12/27 | | |
NCT04967560: The Efficacy and Safety of ALIC/NAcc-DBS for Treatment-refractory OCD |
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| Recruiting | N/A | 64 | RoW | deep brain stimulation | Shanghai Mental Health Center, West China Hospital, Huashan Hospital, The First Affiliated Hospital of Zhengzhou University, Hunan Brain Hospital, First Affiliated Hospital of Kunming Medical University, Changhai Hospital, SceneRay Corporation, Limited | Obsessive-Compulsive Disorder | 07/24 | 10/24 | | |
NCT06754319: Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis |
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| Enrolling by invitation | N/A | 125 | RoW | | Shanghai Mental Health Center | Obsessive-Compulsive Disorder, Tic Disorder | 12/27 | 12/27 | | |
NCT06692114: Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD |
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| Recruiting | N/A | 86 | RoW | Deep Transcranial Magnetic Stimulation, DTMS active, Deep Transcranial Magnetic Stimulation, DTMS sham | Zhen Wang | Obsessive-Compulsive Disorder | 06/27 | 09/27 | | |
NCT06600906: Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer |
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| Recruiting | N/A | 70 | US | Hyperpolarized 13C-Pyruvate, HP 13C, Computed tomography (CT), CT, Magnetic Resonance Imaging (MRI), MRI | University of California, San Francisco, National Cancer Institute (NCI) | Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma, Locally Advanced Pancreatic Ductal Adenocarcinoma | 08/30 | 09/32 | | |
NCT06671457: Model-Driven Individualized Transcranial Direct Current Stimulation for the Treatment of Insomnia Disorders |
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| Recruiting | N/A | 40 | RoW | Active transcranial direct current stimulation, Sham transcranial direct current stimulation | Zhen Wang | Insomnia | 12/25 | 04/26 | | |
NCT06112067: Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders |
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| Recruiting | N/A | 18 | RoW | deep brain stimulation | Shanghai Mental Health Center, SceneRay Corporation, Limited, Huashan Hospital, Shanghai 6th People's Hospital, Changhai Hospital | Deep Brain Stimulation | 12/24 | 12/24 | | |
NCT02395367: Prospective, Observational, Real-world Oral Malignant Tumors Study |
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| Recruiting | N/A | 30000 | RoW | resection, adjuvant radiotherapy, neoadjuvant chemotherapy or adjuvant chemotherapy | Beijing Stomatological Hospital, Peking University Hospital of Stomatology, Beijing Shijitan Hospital of Capital Medical University, Beijing Friendship Hospital, The First Affiliated Hospital of Zhengzhou University, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Beijing Chao Yang Hospital | Head and Neck Neoplasms, Quality of Life, Postoperative Complications | 03/25 | 03/25 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
YANG, Xiaofeng |
NCT06241781: Autologous Tumor Infiltrating Lymphocytes (GT101 Injection) in Patients With Recurrent or Metastatic Cervical Cancer |
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| Recruiting | 2 | 64 | RoW | GT101 injection, Gemcitabine injection | Grit Biotechnology | Adult | 01/27 | 01/27 | | |
| Not yet recruiting | N/A | 104 | RoW | Ventricular irrigation | RenJi Hospital, Southern Medical University, China, First Affiliated Hospital of Zhejiang University, 904 Hospital of the People's Liberation Army Joint Logistic Support Force, Shenzhen Second People's Hospital, First Affiliated Hospital of Wannan Medical College, Huashan Hospital | Central Nervous System Infections | 05/26 | 05/26 | | |
Li, Zhihua |
NCT04300114: A Study of Maintenance Treatment With Fluzoparib in gBRCA/PALB2 Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy |
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| Terminated | 3 | 5 | RoW | Fluzoparib, SHR3162, Placebo | Jiangsu HengRui Medicine Co., Ltd. | Metastatic Pancreatic Cancer | 02/22 | 02/22 | | |
| Active, not recruiting | 3 | 408 | RoW | KN046, placebo | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Advanced Pancreatic Ductal Adenocarcinoma | 04/24 | 08/24 | | |
G-HOPE-001, NCT06238843: A Multicenter, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Gastric or Gastroesophageal Junction Adenocarcinoma |
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| Enrolling by invitation | 3 | 450 | RoW | irinotecan, IBI343, paclitaxel | Innovent Biologics (Suzhou) Co. Ltd. | Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma | 12/26 | 12/27 | | |
NCT02062489: Evaluation of Tamoxifen's Efficacy for ER/PR Negative,ER-beta Positive Operable Breast Cancer Patients |
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| Recruiting | 3 | 688 | RoW | Tamoxifen, Nolvadex, Placebo | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Breast Cancer | 05/25 | 05/26 | | |
EMBER-4, NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer |
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| Recruiting | 3 | 6000 | Europe, Canada, Japan, US, RoW | Imlunestrant, LY3484356, Tamoxifen, Anastrozole, Letrozole, Exemestane | Eli Lilly and Company | Breast Neoplasms | 10/27 | 03/32 | | |
NCT03708822: Study of Docetaxel and Cisplatin Combined With Nimotuzumab As First-Line Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma |
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| Active, not recruiting | 2 | 48 | RoW | Docetaxel and Cisplatin and Nimotuzumab | Sun Yat-sen University | Nasopharyngeal Carcinoma | 07/22 | 06/24 | | |
NCT03830385: Paclitaxel (Albumin Bound),Bleomycin And Cisplatin Or Carboplatin for Recurrent Or Metastatic Squamous Cell Carcinoma Of The Head And Neck |
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| Recruiting | 2 | 51 | RoW | PaclitaxelPaclitaxel (Albumin Bound),Bleomycin combined with Cisplatin or Carboplatin | Sun Yat-sen University | Squamous Cell Carcinoma Of The Head And Neck | 02/21 | 02/26 | | |
NCT04022005: Chidamide + R-GemOx Regimen as Salvage Treatment for Transplant-ineligible Patients With Relapsed/Refractory DLBCL |
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| Completed | 2 | 54 | RoW | Chidamide, Rituximab, Gemcitabine,Oxaliplatin | Sun Yat-sen University | Lymphoma, Large B-Cell, Diffuse | 11/22 | 03/23 | | |
NCT04021992: GVD±R Regimen for ASCT-eligible Patients With Refractory/Relapsed DLBCL |
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| Recruiting | 2 | 48 | RoW | gemcitabine, vinorelbine and doxorubicin liposome, with or without rituximab | Sun Yat-sen University | Lymphoma, Large B-Cell, Diffuse | 07/23 | 12/23 | | |
AK104-217, NCT05859750: A Study of AK104 With Chemotherapy as First-line Treatment in Patients With Advanced Pancreatic Cancer |
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| Recruiting | 2 | 78 | RoW | AK104, Gemcitabine, Nab-Paclitaxel, Liposomal Irinotecan, Oxaliplatin, 5-Fluorouracil/Calcium folinate, Oxaliplatin + Irinotecan + 5-Fluorouracil/Leucovorin | Akeso | Pancreatic Cancer | 06/25 | 12/25 | | |
NCT06500676: A Study of GFH375 in Patients with Advanced Solid Tumors with KRAS G12D Mutations |
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| Recruiting | 1/2 | 290 | RoW | GFH375 | Genfleet Therapeutics (Shanghai) Inc. | KRAS G12D Mutations, Advanced Solid Tumors | 07/28 | 12/28 | | |
| Recruiting | 1/2 | 60 | RoW | PM8002, nab-paclitaxel | Biotheus Inc. | TNBC | 10/26 | 10/26 | | |
KYM901, NCT04805307: Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy, Phase 1 Study of CMG901 |
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| Recruiting | 1 | 162 | RoW | CMG901 | Keymed Biosciences Co.Ltd | Advanced Solid Tumor, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Pancreatic Cancer | 05/24 | 10/24 | | |
CIBI343A101, NCT05458219: A First-in-human Study of IBI343 in Subjects with Locally Advanced Unresectable or Metastatic Solid Tumors |
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| Recruiting | 1 | 470 | US, RoW | IBI343 | Innovent Biologics (Suzhou) Co. Ltd., Innovent Biologics, Inc., TigerMed | Locally Advanced Unresectable or Metastatic Solid Tumors | 12/25 | 12/25 | | |
| Recruiting | 1 | 48 | RoW | SM3321 | Beijing StarMab Biomed Technology Ltd | Locally Advanced or Metastatic Solid Tumors | 08/25 | 10/25 | | |
NCT04320992: A Multicenter Prospective Study of "High Risk" Molecular Typing in Patients With Adult T Lymphoblastic Lymphoma |
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| Recruiting | N/A | 207 | RoW | | Sun Yat-sen University | T-Lymphoblastic Lymphoma/Leukemia | 03/23 | 03/23 | | |
MOST-AVERT, NCT05580523: Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial |
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| Recruiting | N/A | 3000 | RoW | 75 mg acetylsalicylic acid, 75mg Aspirin, 1.5g Metformin, 1.5g Glucophage, 150 mg acetylsalicylic acid, 150mg Aspirin, Placebo of acetylsalicylic acid and Metformin | Chinese University of Hong Kong, Obstetrics & Gynecology Hospital of Fudan University, Shanghai First Maternity and Infant Hospital, West China Second University Hospital, Peking University First Hospital | Preeclampsia | 01/25 | 11/25 | | |
NCT04944563: Comparison of Segmentectomy Versus Lobectomy for Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field |
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| Recruiting | N/A | 1120 | RoW | Segmentectomy, Lobectomy | The First Affiliated Hospital with Nanjing Medical University | Lung Neoplasms, Surgery | 12/29 | 12/29 | | |
NCT04624971: A Novel Prognostic Model of NPI for Risk-Predicting and Clinical Decision-making in Diffuse Large B-Cell Lymphoma in the Rituximab Era |
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| Not yet recruiting | N/A | 2000 | RoW | | Sun Yat-sen University | Diffuse Large B Cell Lymphoma | 11/20 | 11/20 | | |
Geczi, Lajos |
CYCLONE 3, NCT05288166: A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) |
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| Active, not recruiting | 3 | 900 | Europe, Canada, Japan, US, RoW | Abemaciclib, LY2835219, Abiraterone, Prednisone or Prednisolone, Placebo for Abemaciclib | Eli Lilly and Company | Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs, Antineoplastic Agents, Antineoplastic Agents, Hormonal, Androgens, Hormones, Hormones, Hormone Substitutes, and Hormone Antagonists, Abiraterone Acetate, Steroid Synthesis Inhibitors, Cytochrome P-450, Enzyme Inhibitors, Prednisone, Prednisolone, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6 | 02/24 | 10/27 | | |
KL264-01, NCT04152499: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies |
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| Recruiting | 1/2 | 1300 | Canada, US, RoW | SKB264 | Klus Pharma Inc. | Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small-Cell Lung Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma, Breast Cancer | 08/25 | 07/26 | | |
Liu, Qin |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT05879055: A Study of PM8002 in Combination With Chemotherapy in Patients With NEN |
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| Recruiting | 2 | 60 | RoW | PM8002, FOLFIRI | Biotheus Inc. | Neuroendocrine Neoplasm | 01/27 | 01/28 | | |
JJGS and POI, NCT06102655: Effect and Mechanism of Jiajian Guishen Formulation on Premature Ovarian Insufficiency Based on Metabolomics |
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| Completed | 1 | 46 | RoW | Jiajian Guishen Formulation | Shi Yun | Premature Ovarian Insufficiency, Metabolomics, Traditional Chinese Medicine, Mechanism, Clinical Syndrome | 07/24 | 07/24 | | |
NCT06604156: Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring |
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| Recruiting | N/A | 220 | RoW | EEG monitoring | Min Su | Depth of Anesthesia, Nociception, Painless Gastrointestinal Endoscopy | 08/25 | 10/25 | | |
NCT06096766: The Correlation Between Ovarian Function and Serum Biomarkers |
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| Recruiting | N/A | 35 | RoW | blood test | Shi Yun | Premature Ovarian Insufficiency, Diminished Ovarian Reserve, Biomarker, Copper, Ceruloplasmin, Aging | 11/25 | 11/25 | | |
NCT06777589: Quantitative Consciousness Index Monitoring (qNOX) of Sedation During Endoscopy |
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| Not yet recruiting | N/A | 900 | RoW | Monitoring of anesthesia depth | Min Su | Nociception | 07/25 | 08/25 | | |
| Recruiting | N/A | 1332 | RoW | The lying flat (0°-10°) head position for 72 hours, The The head elevation (30°-40°) position for 72 hours | Zhengzhou Yuan | Stroke, Acute, Endovascular Therapy | 11/25 | 04/26 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
Huang, Shihua |
NCT06363994: A Global Phase 3 Study of Orelabrutinib+BR Vs.BR in Pts with TN MCL |
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| Recruiting | 3 | 476 | RoW | Orelabrutinib, Bendamustine Injection, Rituximab, Orelabrutinib Placebo | InnoCare Pharma Inc. | Mantle Cell Lymphoma | 06/31 | 06/32 | | |
NCT04578613: ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL |
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| Recruiting | 3 | 218 | RoW | ICP-022, Chlorambucil, Rituximab | Beijing InnoCare Pharma Tech Co., Ltd. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 12/24 | 06/25 | | |
NCT06004856: Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Chronic Primary Immune Thrombocytopenia |
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| Recruiting | 3 | 195 | RoW | Orelabrutinib, Placebo | Beijing InnoCare Pharma Tech Co., Ltd. | Chronic Primary Immune Thrombocytopenia (ITP) | 12/25 | 04/26 | | |
ICP-CL-01203, NCT06378138: ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma |
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| Recruiting | 2/3 | 226 | RoW | ICP-248, Orelabrutinib | Beijing InnoCare Pharma Tech Co., Ltd. | Hematologic Malignancies | 11/30 | 07/31 | | |
NCT05104775: A Study of GNC-035, a Tetra-specific Antibody, in Participants With Relapsed/Refractory Hematologic Malignancy |
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| Recruiting | 1 | 58 | RoW | GNC-035 | Sichuan Baili Pharmaceutical Co., Ltd., SystImmune Inc. | Hematologic Malignancies | 06/25 | 12/25 | | |
Wei, Jun |
NCT05806333: [18F]FAPI PET/CT in Suspicious Focal Liver Lesions Without FDG Avidity |
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| Recruiting | N/A | 60 | RoW | FAPI PET | Jilin University | Liver Cancer | 06/23 | 06/23 | | |
| Recruiting | N/A | 2000 | RoW | | Peking University Third Hospital, First Affiliated Hospital, Sun Yat-Sen University, Chongqing Medical University, Shengjing Hospital, Peking University, Nankai University, Shanghai First Maternity and Infant Hospital, The First Affiliated Hospital of Anhui Medical University, International Peace Maternity and Child Health Hospital, The Second Hospital of Shandong University, Shandong Provincial Hospital | Twin Pregnancy, Antepartum Condition or Complication, Twin to Twin Transfusion as Antepartum Condition, Pre-Term, Pre-Eclampsia, Twin Monochorionic Diamniotic Placenta, Twin Dichorionic Diamniotic Placenta, High Risk Pregnancy, Twin Placenta | 11/26 | 11/26 | | |
NCT05810324: 18F-FAPI PET/CT in Patients With Various Types of Cancer |
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| Recruiting | N/A | 500 | RoW | 18F-FAPI, FAPI | Jilin University | Cancer | 07/24 | 01/25 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
Lei, Kaijian |
NCT05372120: A Clinical Trial of ICP-192 in Treated Patients With Advanced Solid Tumors With FGF/FGFR Gene Alterations |
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| Recruiting | 2 | 200 | RoW | ICP-192 | Beijing InnoCare Pharma Tech Co., Ltd. | Advanced Solid Tumor | 12/23 | 06/24 | | |
NCT06434610: A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer. |
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| Recruiting | 2 | 90 | RoW | B013, Paclitaxel, Placebo | Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd | Platinum-resistant Recurrent Ovarian Cancer | 12/26 | 12/26 | | |
NCT05126719: A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent Metastatic Nasopharyngeal Carcinoma |
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| Recruiting | 2 | 238 | RoW | MRG003, Capecitabine tablets, Docetaxel injection | Shanghai Miracogen Inc. | Recurrent or Metastatic Nasopharyngeal Carcinoma | 10/24 | 02/25 | | |
| Recruiting | 1/2 | 380 | RoW | PM8002 | Biotheus Inc. | Malignant Neoplasm | 11/25 | 11/25 | | |
Wang, Shanbing |
| Active, not recruiting | 3 | 502 | Europe, Canada, Japan, US, RoW | tisotumab vedotin, TIVDAK, topotecan, vinorelbine, gemcitabine, irinotecan, pemetrexed | Seagen Inc., Genmab | Cervical Cancer | 07/23 | 08/25 | | |
NCT05042375: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer |
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| Recruiting | 3 | 450 | RoW | camrelizumab + famitinib, pembrolizumab, camrelizumab | Jiangsu HengRui Medicine Co., Ltd. | Non-small Cell Lung Cancer | 12/23 | 12/25 | | |
NCT06241781: Autologous Tumor Infiltrating Lymphocytes (GT101 Injection) in Patients With Recurrent or Metastatic Cervical Cancer |
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| Recruiting | 2 | 64 | RoW | GT101 injection, Gemcitabine injection | Grit Biotechnology | Adult | 01/27 | 01/27 | | |
KL264-01, NCT04152499: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies |
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| Recruiting | 1/2 | 1300 | Canada, US, RoW | SKB264 | Klus Pharma Inc. | Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small-Cell Lung Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma, Breast Cancer | 08/25 | 07/26 | | |
Huang, Sihua |
TQB3909-Ib/II-02, NCT05959694: A Clinical Trial on the Safety and Efficacy of TQB3909 Tablets in Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL) . |
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| Recruiting | 1/2 | 107 | RoW | TQB3909 tablet | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 12/25 | 06/26 | | |
Park, Kyung-Hun |
KL264-01, NCT04152499: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies |
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| Recruiting | 1/2 | 1300 | Canada, US, RoW | SKB264 | Klus Pharma Inc. | Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small-Cell Lung Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma, Breast Cancer | 08/25 | 07/26 | | |
Meidong, Xu |
NCT06514989: Efficacy of Low-residue Full Nutritive Formula Powder in Bowel Preparation for Colonoscopy |
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| Recruiting | N/A | 750 | RoW | Low-residue full nutrition formula podwer, Self-prepared low-residue diet | Changhai Hospital | Bowel Preparation for Colonoscopy | 12/24 | 03/25 | | |