| li, xuan j |
NCT06259526: A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression |
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| Recruiting | 2 | 260 | RoW | Placebo group, JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 low-dose group, JS1-1-01 pills; JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 pills; JS1-1-01 placebo pills, JS1-1-01 high-dose group, JS1-1-01 pills; Duloxetine hydrochloride placebo capsules, Active drug group, JS1-1-01 placebo pills; Duloxetine hydrochloride enteric coated capsule | Tasly Pharmaceutical Group Co., Ltd | Depression | 04/25 | 04/25 | | |
GENIUS, NCT04849325: IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease |
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| Recruiting | N/A | 120 | RoW | Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System (IBS Titanâ„¢), Percutaneous Transluminal Angioplasty (PTA) Device | Biotyx Medical (Shenzhen) Co., Ltd. | Critical Limb Ischemia (CLI) | 04/24 | 10/24 | | |
| Cao, Liping |
NCT03932136: Decreasing Risk of Psychosis by Sulforaphane (DROPS Trial) |
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| Recruiting | 3 | 300 | RoW | Sulforaphane, ZHIYINGUOSU, Placebo | Shanghai Jiao Tong University School of Medicine, Shanghai Xuhui District Mental Health Center, Shanghai Pudong Nanhui Mental Health Center, Suzhou Psychiatric Hospital, Second Xiangya Hospital of Central South University, Guangzhou Psychiatric Hospital, Shenzhen Fushan Biotech Co., Ltd., Tianjin Anding Hospital, The First Affiliated Hospital of Zhengzhou University, Shenzhen Kangning Hospital | Clinical High Risk Syndrome of Psychosis | 12/25 | 12/26 | | |
NCT04853485: Repetitive Transcranial Magnetic Stimulation in Early Psychosis and The Functional Connectivity Biotypes |
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| Recruiting | N/A | 300 | RoW | repetitive transcranial magnetic stimulation (rTMS) | Shanghai Jiao Tong University School of Medicine, Suzhou Psychiatric Hospital, Guangzhou Psychiatric Hospital, Shenzhen Kangning Hospital, Tianjin Anding Hospital, Nantong Fourth People's Hospital & Nantong Brain Hospital | Schizophrenia; Psychosis, First Episode Psychosis, Clinical High Risk | 12/23 | 12/24 | | |
| Liu, Hesheng |
| Active, not recruiting | 2 | 62 | US | N-acetylcysteine, NAC, Theta-burst stimulation (TBS) | Medical University of South Carolina, National Institute on Drug Abuse (NIDA) | Cocaine-Related Disorders | 06/25 | 06/25 | | |
NCT06734676: fMRI-guided Transcranial Magnetic Stimulation Treatment for Parkinson's Disease |
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| Completed | N/A | 36 | RoW | Intermittent theta burst stimulation (iTBS) | Changping Laboratory, Henan Provincial People's Hospital | Parkinson's Disease | 04/24 | 05/24 | | |
NCT06166082: Stanford Neuromodulation Therapy (SNT) for the Treatment-Resistant Depression |
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| Recruiting | N/A | 130 | RoW | Active iTBS-DLPFC, Sham iTBS-DLPFC | Changping Laboratory, Xianyue Hospital, Xiamen, Hebei Mental Health Center, Baoding, HuiLongGuan Hospital, Beijing, Wuhan Mental Health Center, Wuhan, Zhumadian Second People's Hospital, Zhumadian | Treatment Resistant Depression | 07/24 | 10/24 | | |
NCT05872243: pBFS Guided rTMS Treating Mild Alzheimer's Disease(AD) |
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| Recruiting | N/A | 45 | RoW | active rTMS, sham rTMS | Changping Laboratory, Xuanwu Hospital, Beijing | Mild Alzheimer's Disease | 05/24 | 08/24 | | |
NCT06255561: pBFS Guided rTMS Over Different Targets for Treatment-Resistant Depression |
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| Not yet recruiting | N/A | 75 | NA | active rTMS stimulating | Changping Laboratory | Major Depressive Disorder, Treatment Resistant Depression, MDD | 12/24 | 01/25 | | |
NCT05735262: pBFS Guided Precision Neuromodulation Treatment for ASD |
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| Recruiting | N/A | 100 | RoW | active iTBS, sham iTBS | Changping Laboratory, China Rehabilitation Research Center | Autism Spectrum Disorder | 03/24 | 01/25 | | |
NCT06255535: pBFS Guided rTMS Over Cognitive Control Network for ASD |
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| Not yet recruiting | N/A | 150 | NA | active iTBS treatment, sham iTBS treatment | Changping Laboratory, Xi'an TCM Hospital of Encephalopathy, Linyi Hedong Rehabilitation Hospital, Jining Medical University, Fujian Maternity and Child Health Hospital, Fujian Children's Hospital | Autism Spectrum Disorder | 04/25 | 09/26 | | |
NCT06350396: pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression |
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| Recruiting | N/A | 270 | RoW | active rTMS treatment, sham rTMS treatment | Changping Laboratory | Treatment Resistant Depression, Major Depressive Disorder | 12/24 | 06/25 | | |
NCT05964036: pBFS-guided High-dose TMS Over DMPFC for Treatment-resistant Major Depressive Disorder |
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| Recruiting | N/A | 45 | RoW | active TMS, sham TMS | Changping Laboratory | Depression, Major Depressive Disorder, Severe Depression | 04/24 | 07/24 | | |
NCT05842304: Individualized Precision rTMS for Language Recovery in Patients After Ischemic Stroke: a Multi-center RCT |
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| Recruiting | N/A | 180 | RoW | active cTBS, sham cTBS | Changping Laboratory | Stroke, Ischemic, Aphasia | 05/25 | 05/26 | | |
NCT05948839: pBFS Guided rTMS Over DMPFC for Treatment-Resistant Depression |
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| Recruiting | N/A | 170 | RoW | active rTMS treatment, sham rTMS treatment | Changping Laboratory, Hebei Mental Health Center, Shandong Daizhuang Hospital, West China Hospital, The Second Affiliated Hospital of Xinxiang Medical University | Treatment Resistant Depression, Major Depressive Disorder | 06/24 | 09/24 | | |
NCT05964023: pBFS Guided VS "5-cm Rule" rTMS Over DLPFC for MDD |
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| Recruiting | N/A | 150 | RoW | pBFS rTMS, 5-cm rTMS | Changping Laboratory | Major Depression, MDD | 12/24 | 03/25 | | |
NCT05929534: pBFS-guided iTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke |
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| Not yet recruiting | N/A | 40 | NA | active intermittent Theta Burst Stimulation, sham intermittent Theta Burst Stimulation | Changping Laboratory | Stroke, Ischemic, Aphasia | 06/24 | 06/25 | | |
NCT05907031: pBFS-guided cTBS Over the Inferior Frontal Gyrus for Aphasia After Ischemic Stroke |
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| Recruiting | N/A | 30 | RoW | active continuous Theta Burst Stimulation, sham continuous Theta Burst Stimulation | Changping Laboratory, First Affiliated Hospital of Fujian Medical University | Stroke, Ischemic, Aphasia | 06/24 | 06/25 | | |
NCT05964049: pBFS Guided rTMS Therapy for Treatment-resistant Obsessive-Compulsive Disorder |
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| Recruiting | N/A | 30 | RoW | active rTMS treatment, sham rTMS treatment | Changping Laboratory | Obsessive-Compulsive Disorder, OCD | 07/24 | 10/24 | | |
NCT05964062: pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Obsessive-Compulsive Disorder |
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| Not yet recruiting | N/A | 30 | NA | active rTMS treatment, sham rTMS treatment | Changping Laboratory | Obsessive-Compulsive Disorder, OCD | 07/24 | 10/24 | | |
NCT05976022: pBFS Guided rTMS Therapy Over Different Targets for Treatment-Resistant Depression |
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| Recruiting | N/A | 50 | RoW | active rTMS | Changping Laboratory | MDD, Major Depressive Disorder, Treatment Resistant Depression | 09/24 | 12/24 | | |
NCT06095778: rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFS |
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| Recruiting | N/A | 100 | RoW | active rTMS | Changping Laboratory | MDD, Major Depressive Disorder, Treatment Resistant Depression | 09/24 | 10/24 | | |
NCT05957341: pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD |
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| Not yet recruiting | N/A | 50 | NA | active rTMS: 20min inter-session interval, active rTMS: 50min inter-session interval, sham rTMS: 20min inter-session interval, sham rTMS: 50min inter-session interval | Changping Laboratory | Moderate Depression, Major Depressive Disorder, Severe Depression | 07/24 | 08/24 | | |
NCT05842278: The Dosage Effect of pBFS Guided rTMS Treatment for MDD |
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| Recruiting | N/A | 100 | RoW | 4 session rTMS, 6 session rTMS, 8 session rTMS, 10 session rTMS, sham rTMS | Changping Laboratory, Beijing HuiLongGuan Hospital | Moderate Depression, Major Depressive Disorder, Severe Depression | 07/24 | 10/24 | | |
NCT05842291: pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Depression |
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| Recruiting | N/A | 60 | RoW | Active rTMS with short inter-session interval, Sham rTMS with short inter-session interval, Active rTMS with long inter-session interval | Changping Laboratory, Beijing HuiLongGuan Hospital | Treatment-Resistant Depression | 08/24 | 11/24 | | |
NCT05957354: pBFS-guided Dual-target cTBS for Aphasia After Stroke |
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| Recruiting | N/A | 60 | RoW | active continuous Theta Burst Stimulation, sham continuous Theta Burst Stimulation | Changping Laboratory | Stroke, Aphasia | 08/24 | 08/25 | | |
NCT05957445: pBFS-guided Multi-target cTBS for Aphasia After Stroke |
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| Recruiting | N/A | 60 | RoW | active continuous Theta Burst Stimulation, sham continuous Theta Burst Stimulation | Changping Laboratory | Stroke, Aphasia | 08/24 | 08/25 | | |
NCT06031948: pBFS-guided Noninvasive Neuromodulation for Pre-school Children With ASD |
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| Not yet recruiting | N/A | 50 | NA | active iTBS, sham iTBS | Changping Laboratory, Henan Provincial People's Hospital | Autism Spectrum Disorder | 08/24 | 01/25 | | |
NCT05976009: pBFS-Guided rTMS Therapy Over Different Targets for Treatment-Resistant Depression |
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| Recruiting | N/A | 80 | RoW | active rTMS stimulating | Changping Laboratory | Major Depressive Disorder, Treatment Resistant Depression, MDD | 08/24 | 09/24 | | |
NCT05999318: pBFS-guided cTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke |
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| Recruiting | N/A | 40 | RoW | active continuous Theta Burst Stimulation, sham continuous Theta Burst Stimulation | Changping Laboratory | Stroke, Ischemic, Aphasia | 08/25 | 08/26 | | |
NCT05890846: Precision TMS Treatment Guided by Personalized Brain Functional Sectors (pBFS) for ASD |
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| Recruiting | N/A | 66 | RoW | active iTBS, sham iTBS, traditional 1on1 course | Changping Laboratory, Henan Provincial People's Hospital, China Rehabilitation Research Center | Autism Spectrum Disorder | 09/24 | 09/25 | | |
NCT05969548: pBFS-guided cTBS at Different Doses for Aphasia After Stroke |
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| Recruiting | N/A | 60 | RoW | active 1200-pulse continuous Theta Burst Stimulation, active 2400-pulse continuous Theta Burst Stimulation, active 3600-pulse continuous Theta Burst Stimulation, sham 1200-pulse continuous Theta Burst Stimulation, sham 2400-pulse continuous Theta Burst Stimulation, sham 3600-pulse continuous Theta Burst Stimulation | Changping Laboratory | Stroke, Aphasia | 09/24 | 09/25 | | |
NCT06086938: pBFS-guided cTBS Combined With iTBS Over the Superior Frontal Gyrus for Aphasia After Ischemic Stroke |
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| Not yet recruiting | N/A | 40 | NA | active cTBS combined with iTBS, sham cTBS combined with iTBS | Changping Laboratory | Stroke, Ischemic, Aphasia | 10/24 | 10/25 | | |
NCT06112652: Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique |
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| Recruiting | N/A | 100 | RoW | 4 session rTMS, 6 session rTMS, 8 session rTMS, 10 session rTMS, sham rTMS | Changping Laboratory, Wuhan Mental Health Centre | Moderate Depression, Major Depressive Disorder, Severe Depression | 10/24 | 12/24 | | |
| Ning, Yuping |
| Active, not recruiting | 4 | 800 | RoW | Sodium Oligomannate Capsules (GV-971) | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer Disease | 01/25 | 06/25 | | |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT04825860: A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase |
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| Terminated | 2/3 | 83 | Japan, RoW | SEP-363856 50 mg, SEP-363856 75 mg, Placebo | Sumitomo Pharma Co., Ltd. | Schizophrenia | 10/23 | 10/23 | | |
NCT06095778: rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFS |
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| Recruiting | N/A | 100 | RoW | active rTMS | Changping Laboratory | MDD, Major Depressive Disorder, Treatment Resistant Depression | 09/24 | 10/24 | | |
| Fukasawa, Takashi |
NCT04825860: A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase |
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| Terminated | 2/3 | 83 | Japan, RoW | SEP-363856 50 mg, SEP-363856 75 mg, Placebo | Sumitomo Pharma Co., Ltd. | Schizophrenia | 10/23 | 10/23 | | |
| Zhou, Yanling |
NCT06095778: rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFS |
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| Recruiting | N/A | 100 | RoW | active rTMS | Changping Laboratory | MDD, Major Depressive Disorder, Treatment Resistant Depression | 09/24 | 10/24 | | |
