The Medical University of South Carolina
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 29 Trials 
101 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Sleckman, Bethany G
NCT01041703: Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Recruiting
3
747
US, RoW
clofarabine, cytarabine, daunorubicin hydrochloride, decitabine
Eastern Cooperative Oncology Group, National Cancer Institute (NCI)
Leukemia
02/19
 
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Recruiting
3
1016
Europe, Canada, Japan, US, RoW
LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed
Eli Lilly and Company, Loxo Oncology, Inc.
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
10/26
10/29
AZUR-2, NCT05855200: Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

Recruiting
3
711
Europe, Canada, Japan, US, RoW
Dostarlimab, CAPEOX, FOLFOX
GlaxoSmithKline
Colonic Neoplasms, Neoplasms, Colon
12/28
12/30
NCT01595048 / 2010-019224-31: Combination Chemotherapy With or Without Rituximab in Treating Younger Patients With Stage III-IV Non-Hodgkin Lymphoma or B-Cell Acute Leukemia

Active, not recruiting
2/3
640
US, Canada, RoW
Rituximab, MOAB IDEC-C2B8, Prednisone, Etoposide, Lastet, Doxorubicin Hydrochloride, Cytarabine, CHX-3311, U-19920, Vincristine Sulfate, Kyocristine, Oncovin, VCR, Vincasar, Cyclophosphamide, Methotrexate, Methylprednisolone, MePRDL, Leucovorin Calcium, CF, Therapeutic Hydrocortisone, Aeroseb-HC, Cetacort, HC, Laboratory Biomarker Analysis
Children's Oncology Group, National Cancer Institute (NCI)
Childhood B Acute Lymphoblastic Leukemia, Childhood Burkitt Leukemia, Childhood Diffuse Large Cell Lymphoma, Mediastinal (Thymic) Large B-Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma
12/20
12/20
NCT05234177: Tempus CRC Surveillance Study: a CtDNA Biomarker Profiling Study of Patients with CRC Using NGS Assays

Recruiting
N/A
160
US
Observation
Tempus AI
Colorectal Cancer
02/25
02/27
NCT05236114: GEMINI-NSCLC: NSCLC Biomarker Study

Recruiting
N/A
1200
US
Observation
Tempus AI, AstraZeneca
Non-Small Cell Lung Cancer
06/29
06/29
NCT01817192: Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer

Active, not recruiting
N/A
420
Europe, US
Adjuvant Chemotherapy, Radiographic surveillance, 14-Gene Prognostic Assay
Razor Genomics, Encore Clinical
Non-Small Cell Lung Cancer
05/27
05/27
NCT00904241: Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Recruiting
N/A
10000
Europe, Canada, US, RoW
Cytology Specimen Collection Procedure, Cytologic Sampling, Laboratory Biomarker Analysis
Children's Oncology Group, National Cancer Institute (NCI)
Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4 Neuroblastoma, Stage 4S Neuroblastoma
01/00
 
NCT00736749: Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Recruiting
N/A
5000
US
Assessment of Therapy Complications, Questionnaire Administration
Children's Oncology Group, National Cancer Institute (NCI)
Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
01/00
 
Milstone, Aaron
TETON, NCT04708782: Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis

Hourglass May 2024 - Aug 2024 : Topline data for IPF
Hourglass Jan 2023 - Mar 2023 : Enrollment completion of TETON trial for IPF
Recruiting
3
576
Canada, US
Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer
United Therapeutics
Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
06/25
06/25
TETON-PPF, NCT05943535: Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis

Recruiting
3
698
Canada, US, RoW
Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer
United Therapeutics
Progressive Pulmonary Fibrosis, Interstitial Lung Disease
11/27
11/27
NCT05130970 / 2021-003162-12: Garadacimab Safety, Pharmacokinetics, and Pharmacodynamics in Idiopathic Pulmonary Fibrosis

Completed
2
81
Europe, Canada, US, RoW
Garadacimab, Factor XIIa antagonist monoclonal antibody, CSL312, Placebo
CSL Behring
Idiopathic Pulmonary Fibrosis
01/24
01/24
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis

Jan 2024 - Dec 2024: Data from trial for diffuse cutaneous systemic sclerosis
Terminated
2
153
Europe, Canada, Japan, US, RoW
HZN-825, Placebo
Amgen
Idiopathic Pulmonary Fibrosis
07/24
01/25
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
75
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
07/25
NCT06283355: Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Recruiting
1
175
US
Nasal Microbiota Transplant (NMT), Placebo
Johns Hopkins University
Staphylococcus Aureus, Microbial Colonization, Neonatal Infection
06/26
12/26
NMT Protocol 3, NCT06805994: Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment

Not yet recruiting
1
175
US
Nasal Microbiota Transplant (NMT), Placebo
Johns Hopkins University
Staphylococcal Aureus Infection, Microbial Colonization, Pediatric Infection, S. Aureus Colonization, Microbial Transplant
01/27
06/27
NCT05695196: Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant

Active, not recruiting
1
34
US
nasal microbiota transplant (NMT), Placebo
Johns Hopkins University, National Institute of Allergy and Infectious Diseases (NIAID)
Staphylococcus Aureus, Microbial Colonization, Neonatal Infection
06/25
12/25
BrighT STAR, NCT04987840: A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

Enrolling by invitation
N/A
15
US
Johns Hopkins University, National Institute of Allergy and Infectious Diseases (NIAID), Agency for Healthcare Research and Quality (AHRQ)
Ventilator Associated Pneumonia, Tracheobronchitis
01/26
06/27
Silvestri, Gerard A
NEWTON, NCT03831386: Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

Recruiting
N/A
200
Europe, US
Vacuum-Based IPC, Gravity-Based IPC
Johns Hopkins University, Rocket Medical plc, Swedish Medical Center, Medical University of South Carolina, University of Oxford, Vanderbilt University Medical Center, Northwest Community Healthcare
Pleural Effusion
12/26
12/26
ALTITUDE, NCT04171492: Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules

Recruiting
N/A
2000
Canada, US
Biodesix, Inc.
Nodule Solitary Pulmonary, Non-small Cell Carcinoma
12/25
12/26
Cook, Chad E
NCT06262880: Dietary Supplementation on Gastrointestinal Barrier Function

Recruiting
N/A
126
US
plant derived phenolics, Microcrystaline cellulose (MCC)
Brightseed
Intestinal Permeability
12/24
02/25
SS-MECH, NCT05940012: Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

Recruiting
N/A
126
US
Manual Therapy, Force based manipulations
Duke University, Saint-Joseph University, The Medical University of South Carolina, University of Colorado - Anschutz Medical Campus
Chronic Neck Pain
09/25
09/25
NCT06548048: Dietary Supplementation on Fat Oxidation

Recruiting
N/A
16
US
Dietary supplement containing plant derived phenolics, Microcrystaline cellulose
Brightseed
Overweight, Obesity
11/24
12/24
Woodbury, Michelle Lynne
eWELL, NCT06782321: Emotional Recovery Post-Stroke

Not yet recruiting
N/A
80
NA
modified Cognitive Behavioral Therapy (mCBT), Occupational or Speech Therapy
Medical University of South Carolina, The Duke Endowment
Stroke, Mental Health Wellness 1
12/27
12/27
Smith, Sarah
NCT04155983: High Versus Low Adductor Canal Block

Recruiting
4
140
US
Ropivacaine, naropin
Carilion Clinic
Osteo Arthritis Knee
12/21
12/21
NCT03367572: Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer

Completed
3
1351
US
Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Fluorodelta, Fortecortin, Gammacorten, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, Visumetazone, Laboratory Biomarker Analysis, Netupitant/Palonosetron Hydrochloride, Akynzeo, Olanzapine, LY 170053, Zydis, Zyprexa, Zyprexa Zydis, Placebo, placebo therapy, PLCB, sham therapy, Prochlorperazine, RP 6140, SKF-4657, Quality-of-Life Assessment, Quality of Life Assessment
University of Rochester NCORP Research Base, National Cancer Institute (NCI)
Breast Carcinoma
04/24
04/24
NCT04829539: Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Chemotherapy

Recruiting
3
400
US
Behavioral Intervention, Behavior Conditioning Therapy, Behavior Modification, Behavior or Life Style Modifications, Behavior Therapy, Behavioral Interventions, Behavioral Modification, Behavioral Therapy, Behavioral Treatment, Behavioral Treatments, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
University of Rochester NCORP Research Base, National Cancer Institute (NCI)
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
01/27
06/27
FEATS, NCT05227456: Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study

Terminated
2
3
Canada
Etonogestrel 68mg implant, Nexplanon
Saskatchewan Health Authority - Regina Area, University of Saskatchewan
Abnormal Uterine Bleeding, Dysmenorrhea
04/24
04/24
SAMATI, NCT05138068: Social Anxiety MDMA-Assisted Therapy Investigation

Active, not recruiting
2
90
US
MDMA, 3,4-Methylenedioxymethamphetamine, Psychotherapy
Jason B Luoma, Oregon Research Institute Center for Evaluation Services, Multidisciplinary Association for Psychedelic Studies, Portland Psychotherapy Clinic, Research, and Training Center
Social Anxiety Disorder
08/25
08/25
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
75
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
07/25
NCT05754073: Oxytocin Effects on Bone in Children with Autism Spectrum Disorder

Recruiting
2
96
US
1. Intranasal oxytocin spray, 2. Intranasal placebo spray, 3. Intranasal Oxytocin spray
Elizabeth Austen Lawson, United States Department of Defense, University of Virginia
Autism Spectrum Disorder, Bone Health
10/25
10/26
BTCRC-LUN17-127, NCT03575793: A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

Checkmark Initial data from trial in combination with opdivo and yervoy for recurrent small cell lung cancer at ASCO 2021
Jun 2021 - Jun 2021: Initial data from trial in combination with opdivo and yervoy for recurrent small cell lung cancer at ASCO 2021
Checkmark Data from combination with nivolumab and ipilimumab for 2L & 3L SCLC
May 2021 - May 2021: Data from combination with nivolumab and ipilimumab for 2L & 3L SCLC
Checkmark From trial in combination with nivolumab and plinabulin for recurrent SCLC at ASCO 2021
More
Completed
1/2
39
US
Nivolumab, Opdivo, Plinabulin, Ipilimumab, Yervoy
Salma Sabbour, BeyondSpring Pharmaceuticals Inc., Bristol-Myers Squibb, Rutgers Cancer Institute of New Jersey
Lung Cancer, SCLC
09/23
07/24
NCT04339439: Does Addition of a Vessel Loop in Wound Closure Improve Suture Removal?

Terminated
N/A
47
US
Vessel loop (FDA product code FZZ)
Carilion Clinic
Patient Satisfaction, Suture, Complication
11/21
07/22
NICE-CF, NCT05362344: Colorectal Cancer Screening in Cystic Fibrosis

Active, not recruiting
N/A
350
US
Stool tests, Stool-based Fecal Immunochemical Testing (FIT) test and Stool-based DNA test (Cologuard) test.
University of Washington, the Collaborative Health Studies Coordinating Center, Cystic Fibrosis Foundation
Cystic Fibrosis, Colorectal Cancer, Adenoma
03/25
06/25
Lee, Lara Wine
NCT05070754: Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca

Completed
4
17
US
Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP), Non-thermal atmospheric pressure plasma (NTAP), Cryotherapy, Cold Therapy, Liquid Nitrogen, Canthardin Collodion, Cantharidin
Medical University of South Carolina, The Skin Center Dermatology Group
Verruca Vulgaris, Molluscum Contagiosum Skin Infection
12/22
12/22
NCT05372419: A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color

Active, not recruiting
3
80
US
Lebrikizumab, LY3650150, DRM06
Eli Lilly and Company
Atopic Dermatitis
05/24
02/25
NCT05937672: Cold Atmospheric Plasma Device Extension Study

Recruiting
3
40
US
Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP), Non-thermal atmospheric pressure plasma (NTAP)
Medical University of South Carolina, The Skin Center Dermatology Group
Verruca Vulgaris, Molluscum Contagiosum
05/25
07/25
ADorable-1, NCT05559359: A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Recruiting
3
360
Europe, Canada, Japan, US, RoW
Lebrikizumab, LY3650150, DRM06, Placebo, Topical Corticosteroid (TCS)
Eli Lilly and Company, Dermira, Inc.
Atopic Dermatitis, Eczema
02/26
02/27
BRAVE-AA-PEDS, NCT05723198: A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

Recruiting
3
595
Europe, Canada, Japan, US, RoW
Baricitinib, LY3009104, Placebo
Eli Lilly and Company
Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases, Skin Diseases, Pathological Conditions, Anatomical
09/24
08/29
ADorable-2, NCT05735483: A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Enrolling by invitation
3
310
Europe, Canada, Japan, US, RoW
Lebrikizumab, LY3650150, Placebo
Eli Lilly and Company
Atopic Dermatitis, Eczema
06/26
06/26
BRAVE-AA1, NCT03570749: A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata

Checkmark Efficacy and safety data from BRAVE-AA1 trial in adults with severe alopecia areata
Apr 2021 - Apr 2021: Efficacy and safety data from BRAVE-AA1 trial in adults with severe alopecia areata
Checkmark From BRAVE-AA1 trial for alopecia areata
Oct 2020 - Oct 2020: From BRAVE-AA1 trial for alopecia areata
Active, not recruiting
2/3
824
Japan, US, RoW
Baricitinib, LY3009104, Placebo
Eli Lilly and Company, Incyte Corporation
Alopecia Areata
02/21
01/25
NCT06073132: An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)

Recruiting
2/3
80
Europe, US, RoW
AC-203, Vehicle
TWi Biotechnology, Inc.
Generalized Epidermolysis Bullosa Simplex
08/25
03/26
NCT05342519: Daily Topical Rapamycin for Vitiligo

Active, not recruiting
2
20
US
Rapamycin, Sirolimus, rapamune, Placebo
Medical University of South Carolina, American Skin Association
Vitiligo
08/25
08/25
NCT06046729: A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Recruiting
2
350
Europe, Canada, US, RoW
Eltrekibart, LY3041658, Placebo
Eli Lilly and Company
Hidradenitis Suppurativa
08/25
07/26
NCT03827798 / 2018-002757-30: Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

Active, not recruiting
2
248
Europe, US, RoW
CFZ533, Placebo to CFZ533, LYS006, Placebo to LYS006, MAS825, Placebo to MAS825, LOU064 25mg, LOU064 100mg, Placebo to LOU064, VAY736, Placebo to VAY736
Novartis Pharmaceuticals
Hidradenitis Suppurativa
12/24
12/26
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Tummala, Mohan
NCT05234177: Tempus CRC Surveillance Study: a CtDNA Biomarker Profiling Study of Patients with CRC Using NGS Assays

Recruiting
N/A
160
US
Observation
Tempus AI
Colorectal Cancer
02/25
02/27
NCT05236114: GEMINI-NSCLC: NSCLC Biomarker Study

Recruiting
N/A
1200
US
Observation
Tempus AI, AstraZeneca
Non-Small Cell Lung Cancer
06/29
06/29
Richardson, Irma M
NCT05582434: Experience With Topical Acne Treatment

Recruiting
1
72
US
Adapalene Gel, Differin, Adapalene Gel and the clindamycin phosphate/benzoyl peroxide gel, Differin and ONEXTON, adapalene, benzoyl peroxide gel, and clindamycin phosphate gel every day., Differin, Epsolay, Clindamycin
Wake Forest University Health Sciences, Bausch Health Americas, Inc.
Acne
05/25
11/25
NCT05391178: Improving Disease Severity

Active, not recruiting
N/A
13
US
Lumiton yarn sleeve, Lumiton yarn hat, Lumiton yarn shirt
Wake Forest University Health Sciences
Psoriasis, Alopecia Areata, Polymorphous Light Eruption
02/25
10/25
NCT03168347: Assessing Patient Confidence in Biologic Medications

Active, not recruiting
N/A
400
US
Anecdotal Evidence, Research Study Evidence, Anecdotal + Research Study Evidence, No Evidence
Wake Forest University Health Sciences
Psoriasis
05/25
12/25
NCT05570955: Deucravacitinib Adherence Study

Recruiting
N/A
40
US
Text reminder
Wake Forest University Health Sciences, Bristol-Myers Squibb
Psoriasis
07/25
12/25
NCT03756792: Assessing Patient Anxiety During Mohs Micrographic Surgery

Active, not recruiting
N/A
100
US
Normal Education Material, Vignette
Wake Forest University Health Sciences
Anxiety
07/25
12/25
NCT06244212: Topical Treatment for Atopic Dermatitis

Recruiting
N/A
30
US
Demonstration of applying triamcinolone cream, Mobile App Use, Standard of Care
Wake Forest University Health Sciences
Atopic Dermatitis
03/25
10/25
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Rowley, Courtney
ASCEND, NCT05295732: The Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis

Completed
3
209
Europe, Canada, US
TMB-001, Matching Vehicle
Timber Pharmaceuticals Inc., LEO Pharma
Ichthyosis
06/24
09/24
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Yeadon, Kenreka
NCT03401489: PACESETTER: Program to Avoid Cerebrovascular Events Through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor

Completed
N/A
120
US
PACESETTER
Northern California Institute of Research and Education, University of South Carolina, Medical University of South Carolina, Regional Medical Center: Orangeburg Hospital
Blood Pressure, Hypertension, Mhealth
02/24
02/24
George, Renuka M
NCT03490357: Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study

Completed
N/A
182
US
Control - Transversus Abdominus Plane Block, Quadratus Lumborum Block
Medical University of South Carolina
Anesthesia
07/23
07/23
Hylton, Jennifer
NCT05234177: Tempus CRC Surveillance Study: a CtDNA Biomarker Profiling Study of Patients with CRC Using NGS Assays

Recruiting
N/A
160
US
Observation
Tempus AI
Colorectal Cancer
02/25
02/27
NCT05236114: GEMINI-NSCLC: NSCLC Biomarker Study

Recruiting
N/A
1200
US
Observation
Tempus AI, AstraZeneca
Non-Small Cell Lung Cancer
06/29
06/29
NCT06538038: Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

Recruiting
N/A
538
US
Osimertinib, Tagrisso, Osimertinib + Chemotherapy, Tagrisso, Cisplatin, Carboplatin, Pemetrexed
PrECOG, LLC., ECOG-ACRIN Cancer Research Group
Non Small Cell Lung Cancer, Epidermal Growth Factor Receptor Gene Mutation, Stage III Lung Cancer, Stage IV Lung Cancer
08/28
08/29
O'Halloran, Bryan
NCT04222244: Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis

Recruiting
N/A
82
US
No intervention will be administered. We are only performing tests and measures.
Des Moines University, Texas Tech University, University of Hartford, Youngstown State University, American Academy of Orthopaedic Manual Physical Therapists
Headache
12/22
12/22
SS-MECH, NCT05940012: Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

Recruiting
N/A
126
US
Manual Therapy, Force based manipulations
Duke University, Saint-Joseph University, The Medical University of South Carolina, University of Colorado - Anschutz Medical Campus
Chronic Neck Pain
09/25
09/25
Wenzel, Abby
NIGHTINGALE, NCT06426628: Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

Recruiting
N/A
2400
US
Veracyte, Inc.
Pulmonary Nodule, Solitary, Lung Cancer
12/24
03/27
TARGET, NCT04182815: Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung

Completed
N/A
691
Canada, US, RoW
Robotic assisted bronchoscopy, Robotic assisted bronchoscopy with Monarch platform
Auris Health, Inc.
Pulmonary Nodule, Lung Cancer
12/23
12/23
Gross, Christopher
NCT01191151: Web Based Orthopaedic Sports Medicine Registry

Terminated
N/A
12500
Europe, Canada, US, RoW
Arthrex, Inc.
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist, Degenerative and Traumatic Pathology of the Hip
07/23
07/23
NCT04784156: Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis

Not yet recruiting
N/A
60
US
Subtalar (Talocalcaneal) Arthrodesis, DynaNail Mini
MedShape, Inc, Medical University of South Carolina
Foot Arthritis
03/24
03/24
NCT04770870: Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

Recruiting
N/A
232
US
Hintermann Series H3 Total Ankle Replacement System
DT MedTech, LLC
Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle, Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
04/29
04/29
ITAR2, NCT04594993: INFINITY™ With ADAPTIS™ Technology Study

Active, not recruiting
N/A
200
US
INFINITY™ with ADAPTIS™ Technology Total Ankle System
Stryker Trauma and Extremities
Arthritis, Rheumatoid
11/33
11/35
Swanson, Garth R
NCT04304950: Chronotherapy in Inflammatory Bowel Disease

Completed
4
28
US
Evening Group, Morning Group
Rush University Medical Center
Inflammatory Bowel Diseases
12/21
04/23
NCT04111900: Effect of Sleep on the Recovery of Patients Admitted to the ICU

Completed
N/A
51
US
Sleep/Circadian Friendly
Rush University Medical Center
Critical Illness, Circadian Dysregulation, Delirium
12/19
01/20
NCT05180279: The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis

Completed
N/A
19
US
7-day sleep lab
Rush University Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Ulcerative Colitis
06/24
06/24
NCT05213234: Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis

Recruiting
N/A
60
US
Chronotherapy
Rush University Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Ulcerative Colitis
06/25
06/25
NCT05579392: A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis

Recruiting
N/A
30
US
Bright Light Therapy, Placebo Retimer Device
Rush University Medical Center
Inflammatory Bowel Disease
05/25
05/25
Scott, Daniel
NCT01191151: Web Based Orthopaedic Sports Medicine Registry

Terminated
N/A
12500
Europe, Canada, US, RoW
Arthrex, Inc.
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist, Degenerative and Traumatic Pathology of the Hip
07/23
07/23
NCT04784156: Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis

Not yet recruiting
N/A
60
US
Subtalar (Talocalcaneal) Arthrodesis, DynaNail Mini
MedShape, Inc, Medical University of South Carolina
Foot Arthritis
03/24
03/24
NCT05364606: Patient Specific Talus Spacer Post Approval Study

Recruiting
N/A
50
US
Patient Specific Talus Spacer
Paragon 28
Avascular Necrosis of the Talus
08/29
11/29
Cypcar, David
NCT06372496: Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Recruiting
4
1136
Canada, Japan, US, RoW
Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate, Inhaled corticosteroids/long-acting beta-2 agonists
GlaxoSmithKline
Asthma
03/26
03/26
PREPARED-1, NCT06339008: A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis

Recruiting
3
450
Europe, US, RoW
LY3650150, Placebo, Standard therapy for INCS
Eli Lilly and Company
Perennial Allergic Rhinitis (PAR)
10/25
02/27
NCT06261957: A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With Asthma

Recruiting
3
412
Europe, Canada, US, RoW
Salbutamol HFA-134a, Salbutamol HFA-152a
GlaxoSmithKline
Asthma
04/25
04/25
NIMBLE, NCT04718389 / 2020-003612-28: A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype

Hourglass Feb 2024 - Jun 2024 : Acceptance of regulatory submission in China for CRSwNP
Active, not recruiting
3
1667
Europe, Canada, Japan, US, RoW
GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS)
GlaxoSmithKline, Iqvia Pty Ltd
Asthma
10/25
10/25
CALM-CSU, NCT06077773: Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria

Recruiting
2
154
Europe, Canada, US
Oral EP262, Placebo
Escient Pharmaceuticals, Inc
Chronic Spontaneous Urticaria
06/25
07/25
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Hoch, Caroline
NCT04784156: Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis

Not yet recruiting
N/A
60
US
Subtalar (Talocalcaneal) Arthrodesis, DynaNail Mini
MedShape, Inc, Medical University of South Carolina
Foot Arthritis
03/24
03/24
Padilla, Felicia
NCT05654922: Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

Recruiting
3
100
US
ARINA-1, Standard of care only
Renovion, Inc.
Pre-Bronchiolitis Obliterans Syndrome
01/25
06/25
NCT05667662 / 2022-002289-33: Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA

Terminated
2
8
Europe, US, RoW
Itraconazole Powder, PUR1900, Placebo
Pulmatrix Inc., Pulmatrix, Inc.
ABPA
02/24
02/24
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
75
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
07/25
ALTA TIPS, NCT03973372: A 5-year Longitudinal Observational Study of Patients Undergoing TIPS Placement

Active, not recruiting
N/A
852
US
University of Texas Southwestern Medical Center, University of California, San Francisco, Scripps Health, University of Wisconsin, Madison, University of Florida, University of Arizona, Stanford University, Columbia University, Weill Medical College of Cornell University, Baylor Scott and White Health, Mayo Clinic, University of Chicago, Digestive Health Foundation, W.L.Gore & Associates, University of Minnesota, Northwestern University
Cirrhosis, Liver, Transjugular Intrahepatic Portosystemic Shunt (TIPS)
12/25
12/27
NCT05837663: Trifecta-Lung cfDNA-MMDx Study

Recruiting
N/A
600
Europe, Canada, US, RoW
University of Alberta, Natera, Inc., One Lambda
Lung Transplantation
11/26
12/27
NCT03639025: OCS™ Lung TOP Registry For Donor Lungs for Transplantation

Active, not recruiting
N/A
458
US
OCS Lung System
TransMedics
Lung Transplantation
11/25
11/29
Schlichting, David
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Villanueva, Michelle
NCT05634044: Validating eNose Measurement of Daily Fiber Intake

Completed
N/A
22
US
eNose Device
Rush University Medical Center
Dietary Fiber
10/23
10/23
NCT05213234: Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis

Recruiting
N/A
60
US
Chronotherapy
Rush University Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Ulcerative Colitis
06/25
06/25
Hernandez, Daisy
TARGET-DERM, NCT03661866: A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Recruiting
N/A
15000
Europe, Canada, US
Target PharmaSolutions, Inc.
Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa, Vitiligo, Psoriasis, Chronic Spontaneous Urticaria
12/50
12/50
Giovanni, Christine San
NCT02121132: Pediatric Obesity Weight Evaluation Registry (POWER) Study

Completed
N/A
4276
US
Children's Hospital Medical Center, Cincinnati, Helen DeVos Children's Hospital, Mayo Clinic, Duke University, National Association of Children's Hospitals and Related Institutions (NACHRI), Milton S. Hershey Medical Center, University of New Mexico, University of Illinois College of Medicine at Peoria, Children's Hospital Los Angeles, Connecticut Children's Medical Center, The Children's Hospital of San Antonio, Ann & Robert H Lurie Children's Hospital of Chicago, Children's Mercy Hospital Kansas City, Arkansas Children's Hospital Research Institute, Florida Hospital for Children, UCSF Benioff Children's Hospital Oakland, University of Oklahoma, MaineHealth, Seattle Children's Hospital, Eastern Maine Medical Center, University of Florida, University of California, Los Angeles, Gramercy Pediatrics, St. Louis Children's Hospital, Dartmouth-Hitchcock Medical Center, University of Alabama at Birmingham, University of Tulsa, Northern Arizona Healthcare, University of Kentucky, Arnold Palmer Hospital for Children, The Cleveland Clinic
Overweight, Obesity
06/24
06/24
A, Shahrukh
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
75
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
07/25
Empey, Robyn
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
75
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
07/25
Shenoy, Sangeeta
NCT05671835: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis

Recruiting
2
75
US
TTI-101, Placebo
Tvardi Therapeutics, Incorporated
Idiopathic Pulmonary Fibrosis
03/25
07/25
Handy, Danielle
NCT06126003: Gut and Tumor Microbiome in Patients With Early Stage (II-III), Locally Advanced or Advanced ER-positive and HER2-negative Breast Cancer.

Terminated
N/A
2
US
Observation
BioCorteX Inc, Tempus AI
Breast Cancer
07/24
07/24
 

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