University Hospital of North Tees
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 14 Trials 
30 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Mitchell, David
FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
2/3
1800
Europe, Canada, RoW
VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin
St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group
Acute Lymphoblastic Leukaemia
06/25
04/30
NCT04372524: Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

Recruiting
N/A
350
Canada, US
University of British Columbia
Chronic Graft-versus-Host-Disease, Leukemia, Allogeneic Hematopoietic Stem Cell Transplantation, Blood Cancer, Non-Malignant Hematologic and Lymphocytic Disorder
01/24
01/25
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Harrison, Richard
NCT01191151: Web Based Orthopaedic Sports Medicine Registry

Terminated
N/A
12500
Europe, Canada, US, RoW
Arthrex, Inc.
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist, Degenerative and Traumatic Pathology of the Hip
07/23
07/23
Agarwal, Anil
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
Crawford, Susan
ELAN, NCT03148457: Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial

Completed
N/A
2013
Europe, Japan, RoW
Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)
Insel Gruppe AG, University Hospital Bern
Ischaemic Stroke
12/22
05/23
Wilson, David R
ACTIV-4, NCT04505774 / 2020-004285-19: Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE

Completed
4
3591
Europe, US, RoW
theraputic heparin, unfractionated heparin, Enoxaparin, Dalteparin, Tinzaparin, Heparin, prophylactic heparin, enoxaparin, dalteparin, Fondparinux, P2Y12, Ticagrelor, Prasugrel, Clopidogrel, Crizanlizumab Injection, SGLT2 inhibitor, dapagliflozin, empagliflozin, canagliflozin, ertugliflozin
Matthew Neal MD, National Heart, Lung, and Blood Institute (NHLBI)
Covid19
08/23
01/24
SCOPE2, NCT02741856 / 2015-001740-11: Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation

Recruiting
2/3
584
Europe
Carboplatin, Paclitaxel, Cisplatin, Capecitabine, Radiotherapy
Lisette Nixon, Cancer Research UK
Oesophageal Cancer
04/21
04/23
NCT05411107: Oral Iloprost for the Prevention of Lung Cancer In Former Smokers

Withdrawn
2
80
NA
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bronchial Brush Biopsy, bronchial brushing, Bronchoscopy, Iloprost, Ciloprost, Iloprost Clathrate, Ventavis, ZK 36374, Placebo Administration, Questionnaire Administration
National Cancer Institute (NCI)
Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease, Lung Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Tobacco-Related Carcinoma
12/26
06/27
NCT05374278: First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

Recruiting
1/2
102
US
[18F]RP-115 PET/MRI or PET/CT and MRI
David Wilson, Rio pharmaceuticals Inc.
Alzheimer Disease, Frontotemporal Dementia, Dementia
04/25
07/26
NCT04154488: A Study of Mavorixafor in Participants With Congenital Neutropenia and Chronic Idiopathic Neutropenia Disorders

Completed
1/2
32
US
Mavorixafor, X4P-001
X4 Pharmaceuticals
Neutropenia
08/24
08/24
NCT01736592: Phase I/II Follow-up Study of SAR422459 in Patients With Stargardt's Macular Degeneration

Calendar Jan 2034 - Dec 2034: Data in Stargardt’s macular degeneration
Active, not recruiting
1/2
27
Europe, US
Long term follow up in all patients who received SAR422459 in previous study TDU13583
Sanofi
Stargardt's Disease
08/33
08/33
NCT03922932: WF and PR OCTA in Diabetic Retinopathy

Active, not recruiting
N/A
290
US
Oregon Health and Science University
Diabetic Retinopathy
12/25
12/25
ORCA, NCT04325334: Osteoarthritis Running & Cartilage Assessment

Recruiting
N/A
80
Canada
Running volume increase
University of British Columbia
Osteoarthritis, Knee
12/24
12/24
BRITISH, NCT05568069: RCT of Implantable Defibrillators in Patients with Non Ischemic Cardiomyopathy, Scar and Severe Systolic Heart Failure

Recruiting
N/A
2504
Europe
Implantable Cardioverter-Defibrillator (ICD) or Cardiac Resynchronisation Therapy Defibrillator (CRTD)
University Hospital Southampton NHS Foundation Trust, British Heart Foundation, University of Southampton
Heart Failure
04/26
04/36
NCT04165564: DECAMP 1 PLUS: Prediction of Lung Cancer Using Noninvasive Biomarkers

Active, not recruiting
N/A
85
US
Institutional standard of care, Biosamples of airway and blood
Boston University, Johnson & Johnson, American College of Radiology Imaging Network
Pulmonary Disease
12/26
12/26
NCT05412927: AngelMed Guardian® System PMA Post Approval Study

Recruiting
N/A
500
US
PMA P150009 AngelMed Guardian® System
Angel Medical Systems
Acute Coronary Syndrome
12/26
12/26
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
SAFETY, NCT03944798: Surveillance AFter Extremity Tumor surgerY

Active, not recruiting
N/A
310
Europe, Canada, US, RoW
Frequency: Every 3 Months, Frequency: Every 6 Months, Imaging Modality: Chest Radiograph (CXR), Imaging Modality: Chest CT
McMaster University, Hamilton Academic Health Sciences Organization, Canadian Cancer Society (CCS), Canadian Institutes of Health Research (CIHR), American Academy of Orthopaedic Surgeons, Musculoskeletal Tumor Society
Soft Tissue Sarcoma, Lung Metastases
12/27
12/27
NCT00280202: Detection of Genetic Markers of Lung Cancer

Recruiting
N/A
6000
US
Biopsy of the major carinal area, Biopsy of abnormal & suspicious areas of the bronchial tree, Evaluation of the tumor for DNA mutations, Bronchoalveolar Lavage (BAL) for cytokine analysis, Correlation of flow cytometric & RT PCR for TNM stage, Analysis of lymph nodes
University of Pittsburgh, National Institutes of Health (NIH)
Lung Cancer
12/50
12/50
NCT00904241: Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Recruiting
N/A
10000
Europe, Canada, US, RoW
Cytology Specimen Collection Procedure, Cytologic Sampling, Laboratory Biomarker Analysis
Children's Oncology Group, National Cancer Institute (NCI)
Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4 Neuroblastoma, Stage 4S Neuroblastoma
01/00
 
AREN03B2, NCT00898365: Study of Kidney Tumors in Younger Patients

Recruiting
N/A
8000
Europe, Canada, US, RoW
Cytology Specimen Collection Procedure, Cytologic Sampling, Laboratory Biomarker Analysis
Children's Oncology Group, National Cancer Institute (NCI)
Adult Cystic Nephroma, Anaplastic Kidney Wilms Tumor, Angiolipoma, Cellular Congenital Mesoblastic Nephroma, Classic Congenital Mesoblastic Nephroma, Clear Cell Sarcoma of the Kidney, Congenital Mesoblastic Nephroma, Cystic Partially Differentiated Kidney Nephroblastoma, Diffuse Hyperplastic Perilobar Nephroblastomatosis, Extrarenal Rhabdoid Tumor, Kidney Medullary Carcinoma, Kidney Neoplasm, Kidney Oncocytoma, Kidney Wilms Tumor, Metanephric Adenofibroma, Metanephric Adenoma, Metanephric Stromal Tumor, Metanephric Tumor, Mixed Congenital Mesoblastic Nephroma, Ossifying Renal Tumor of Infancy, Papillary Renal Cell Carcinoma, Renal Cell Carcinoma, Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions, Rhabdoid Tumor of the Kidney, Wilms Tumor
01/00
 
Strong-Sheldrake, Sophia
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
Wilson, Helen
IMPRESS, NCT02222844: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Recruiting
N/A
244
Europe
Preoperative MRI scan
Imperial College London, Pelican Cancer Foundation
Cancer, Colorectal Neoplasms, Colon, Sigmoid, Magnetic Resonance Imaging, General Surgery
12/26
12/31
TRIGGER, NCT02704520 / 2015-003009-40: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial

Recruiting
N/A
441
Europe
High resolution MRI scan, mrTRG assessment
Imperial College London
Rectal Cancer
12/26
12/36
Annamalai, Arun
ELAN, NCT03148457: Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial

Completed
N/A
2013
Europe, Japan, RoW
Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)
Insel Gruppe AG, University Hospital Bern
Ischaemic Stroke
12/22
05/23
Miller, Graham
INJUSTIS, NCT03670576: It's Not JUST Idiopathic Pulmonary Fibrosis Study

Recruiting
N/A
250
Europe
Optional Bronchoscopy, Quality of Life Questionnaires, Blood Samples for Biomarkers, Home Hand Held Spirometry
University of Nottingham, Nottingham University Hospitals NHS Trust
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
11/22
11/22
Brohi, Farooq
NCT03653832 / 2018-001650-98: Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial)

Completed
3
1437
Europe
Dexmedetomidine, Dexdor, Clonidine, Catapres, Propofol, Diprivan
University of Edinburgh, West Hertfordshire Hospitals NHS Trust, Queen's University, Belfast, The University of Queensland, University Hospital of Wales, Edinburgh Napier University, King's College London, University of Warwick, University of Manchester, Royal Surrey County Hospital NHS Foundation Trust, University College, London, NHS Lothian, Imperial College London, University of Cambridge
Critical Illness
12/23
07/24
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
Ramisetty, Narendra
NCT01191151: Web Based Orthopaedic Sports Medicine Registry

Terminated
N/A
12500
Europe, Canada, US, RoW
Arthrex, Inc.
Degenerative and Traumatic Pathology of the Knee, Degenerative and Traumatic Pathology of the Shoulder and Elbow, Degenerative and Traumatic Pathology of the Foot and Ankle, Degenerative and Traumatic Pathology of the Hand and Wrist, Degenerative and Traumatic Pathology of the Hip
07/23
07/23

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