UPMC Shadyside Radiation Oncology
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 66 Trials 
83 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Deutsch, Melvin
NCT01465100: Liver Cell Transplant for Phenylketonuria

Terminated
1/2
1
US
Preparative Radiation Therapy, Hepatocyte Transplant, Immunosuppression, Liver Evaluation, Neuro-psychological Assessment, Whole body Phe oxidation testing, Liver Biopsy
Ira Fox
Phenylketonuria
08/15
06/16
NCT01360606: Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Completed
N/A
9
US
Stereotactic Body Radiation Therapy, CyberKnife, Trilogy, True Beam, Radiosurgery
Susannah Ellsworth
Liver Metastases
07/18
02/21
Bauman, Julie
NCT03811015: Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Suspended
3
636
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Patient Observation, Active Surveillance, deferred therapy, expectant management, Observation, Watchful Waiting, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT
National Cancer Institute (NCI)
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
01/27
01/27
RTOG 1216, NCT01810913: Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Recruiting
2/3
613
Canada, US, RoW
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cetuximab, C 225, C-225, C225, Cetuximab Biosimilar CDP-1, Cetuximab Biosimilar CMAB009, Cetuximab Biosimilar KL 140, Chimeric Anti-EGFR Monoclonal Antibody, Chimeric MoAb C225, Chimeric Monoclonal Antibody C225, Erbitux, IMC-C225, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Docetaxel, Docecad, RP 56976, RP-56976, RP56976, Taxotere, Taxotere Injection Concentrate, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Quality-of-Life Assessment, Quality of Life Assessment
National Cancer Institute (NCI), NRG Oncology
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
01/27
01/27
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
NCT03153982: Ruxolitinib in Operable Head and Neck Cancer

Terminated
2
16
US
Ruxolitinib, Jakafi
University of California, San Francisco, Incyte Corporation
Head and Neck Squamous Cell Carcinoma
10/23
10/23
NCT05121051: Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers

Recruiting
2
120
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Avmacol, Placebo Administration, Questionnaire Administration
National Cancer Institute (NCI)
Cigarette Smoking-Related Carcinoma
12/25
12/27
KEYNOTE-A78, NCT03978689: A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Active, not recruiting
1
85
US
CUE-101, KEYTRUDA®, Pembrolizumab, Pembrolizumab
Cue Biopharma, Merck Sharp & Dohme LLC
Head and Neck Cancer, HPV Positive Oropharyngeal Squamous Cell Carcinoma, HPV-Related Carcinoma
11/24
05/25
Vargo, John
NCT04350424: Driving Skills Recovery Following Procedural Sedation for Gastrointestinal Endoscopy

Terminated
N/A
68
US
The Cleveland Clinic
Anesthesia, Psychomotor Status
03/20
03/20
NCT06006078: Aersosolization During Upper Endoscopy

Completed
N/A
60
US
Endoscopic Patient Facemask, POM Mask
The Cleveland Clinic
Infectious, Gastro-Intestinal Disorder, Safety Issues
10/21
10/21
REVITA-T2Di, NCT04419779: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes

Suspended
N/A
320
Europe, US
Duodenal Mucosal Resurfacing (DMR), Duodenal Mucosal Resurfacing (Sham)
Fractyl Health Inc.
Type 2 Diabetes
06/25
01/26
PREDICT, NCT03448926: The Registry:

Recruiting
N/A
3000
US
Treatment Recommendation Surveys, 7-gene biosignature
PreludeDx, University of South Florida
DCIS
12/25
12/35
Johnson, Jonas T
NCT04608773: Blinded Dry Mouth Spray Crossover Study

Completed
N/A
129
US
Remineralizing Extreme Dry Mouth Spray with Xylitol, Refresh Oral Hydrating Spray, Alcohol-Free Moisturizing Dry Mouth Spray, Biotene
Jonas Johnson, TJA Health, LLC
Xerostomia, Head and Neck Cancer, Xerostomia Following Radiotherapy
11/22
06/23
Heron, Dwight E
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22
Ferris, Robert L
XRAY VISION, NCT05386550 / 2022-001144-18: Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants

Terminated
3
166
Europe, Canada, Japan, US, RoW
Xevinapant (Debio 1143), IMRT, Placebo
EMD Serono Research & Development Institute, Inc., Merck KGaA, Darmstadt, Germany
Head and Neck Cancer
08/24
08/24
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
E3311, NCT01898494: Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Active, not recruiting
2
519
US
Transoral surgery, TOS, intensity-modulated radiation therapy, IMRT, cisplatin, Cis-diaminedichloroplatinum Cis-diaminedichloroplatinum (II), diaminedichloroplatinum, cis-platinum, CDDP, DDP, platinum, Platinol, Platinol-AQ, DACP, NSC 119875 R R, carboplatin, CBDCA, JM-8, NSC-241240, Paraplatin
ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
Human Papilloma Virus Infection, Stage III Squamous Cell Carcinoma of the Oropharynx, Stage IVA Squamous Cell Carcinoma of the Oropharynx, Stage IVB Squamous Cell Carcinoma of the Oropharynx
11/20
12/24
NCT03715946: Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Completed
2
40
US
Nivolumab Injection, BMS-936558, Radiotherapy (RT)
Robert L. Ferris, MD, PhD, Bristol-Myers Squibb
Carcinoma, Squamous Cell of Head and Neck, Oropharynx Squamous Cell Carcinoma
03/23
03/24
CA224-056, NCT04080804: Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

Recruiting
2
80
US
Nivolumab, anti-PD-1 antibody, OPDIVO®, Relatlimab, anti-LAG3 antibody, BMS-986016, Ipilimumab, anti-CTLA4 antibody, Yervoy ®
Dan Zandberg, Bristol-Myers Squibb
Head and Neck Squamous Cell Carcinoma (HNSCC)
05/26
09/26
NCT02734537: Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Recruiting
2
189
US
Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Intensity-Modulated Radiation Therapy, IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis
ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant, Lip and Oral Cavity Squamous Cell Carcinoma, p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma, Stage III Hypopharyngeal Carcinoma AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oral Cavity Verrucous Carcinoma, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IVA Hypopharyngeal Carcinoma AJCC v8, Stage IVA Laryngeal Cancer AJCC v8, Stage IVA Lip and Oral Cavity Cancer AJCC v8, Stage IVA Oral Cavity Verrucous Carcinoma, Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
12/27
12/27
NCT05388773: Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

Recruiting
2
150
US
therapeutic conventional surgery, laboratory biomarker analysis, quality-of-life assessment, quality of life assessment, intensity-modulated radiation therapy, IMRT, Cisplatin, CACP, CDDP, CPDD, DDP, Carboplatin, Carboplat, CBDCA, JM-8, Paraplat, Paraplatin
Heath Skinner
Oropharynx Cancer
06/28
06/30
NCT01935921: Ipilimumab, Cetuximab, and Intensity-Modulated Radiation Therapy in Treating Patients With Previously Untreated Stage III-IVB Head and Neck Cancer

Completed
1
19
US
Cetuximab, Cetuximab Biosimilar CDP-1, Cetuximab Biosimilar CMAB009, Cetuximab Biosimilar KL 140, Chimeric Anti-EGFR Monoclonal Antibody, Chimeric MoAb C225, Chimeric Monoclonal Antibody C225, Erbitux, IMC-C225, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS-734016, Ipilimumab Biosimilar CS1002, MDX-010, MDX-CTLA4, Yervoy, Laboratory Biomarker Analysis
National Cancer Institute (NCI)
Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
10/16
07/18
EPIC-iENE DATA, NCT05936502: Ascertaining the Radiologic Prognostic Importance of Extranodal Extension on Imaging (iENE) in Head and Neck Cancer

Completed
N/A
3500
Europe, US, RoW
Extranodal extension
Head and Neck Cancer International Group
Head and Neck Squamous Cell Carcinoma, Extranodal Extension, Human Papilloma Virus Related Carcinoma
08/23
09/23
BASH OPC, NCT06305676: Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer

Recruiting
N/A
400
US
combined HPV 16 DNA and host gene methylation oral biomarker panel
H. Lee Moffitt Cancer Center and Research Institute, National Institutes of Health (NIH)
Oropharyngeal Cancer, HPV-Related Carcinoma
01/29
01/29
HNC-TACTIC, NCT05117775: Towards A Better Paradigm for Head and Neck Cancer Treatment Applying Artificial Intelligence. .

Recruiting
N/A
10000
Europe
No intervention - Just description and predictive models
Savana Research, Head and Neck Cancer International Group (HNCIG)
Head and Neck Cancer
02/24
12/24
Zeh, Herbert J
Precision Promise, NCT04229004: A Multi-center Trial to Evaluate Multiple Regimens in Metastatic Pancreatic Cancer

Active, not recruiting
3
825
US
Gemcitabine combined with nab-paclitaxel, Dose -mFOLFIRINOX, Dose - Pamrevlumab combined with gemcitabine and nab-paclitaxel, Dose- Canakinumab and Spartalizumab combined with nab-paclitaxel and gemcitabine, Drug: Dose -SM-88
Pancreatic Cancer Action Network
Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma
06/27
06/27
Flickinger, John C
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22
NCT04019262: Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma

Active, not recruiting
1/2
2
US
Radiation Therapy, Temozolomide Oral Product
John Flickinger
Glioblastoma
12/28
07/29
NCT02054689: Fractionated Stereotactic Radiosurgery for Large Brain Metastases

Active, not recruiting
1
20
US
Fractionated Stereotactic Radiosurgery, SRS, SBRT, CyberKnife, Trilogy, True Beam, Radiosurgery
Steven Burton
Large Brain Mets
11/17
04/24
NCT01360606: Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Completed
N/A
9
US
Stereotactic Body Radiation Therapy, CyberKnife, Trilogy, True Beam, Radiosurgery
Susannah Ellsworth
Liver Metastases
07/18
02/21
Snyderman, Carl
NCT04946435: Topical Antibiotic Prophylaxis for Nasal Packing Post-ESBS

Withdrawn
1
60
US
Antibiotic Irrigation
Carl Snyderman
Intracranial Pathology
11/23
12/23
NCT05161780: Evaluation of Endoscopic Surgical Field Clarity Using Hot Saline Versus Lactated Ringer's Irrigation

Completed
1
47
US
Lactated Ringer's Irrigation, Normal Saline
Carl Snyderman
Irrigation
06/24
06/24
Burton, Steven
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22
NCT01360606: Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Completed
N/A
9
US
Stereotactic Body Radiation Therapy, CyberKnife, Trilogy, True Beam, Radiosurgery
Susannah Ellsworth
Liver Metastases
07/18
02/21
Smith, Ryan
PIONEER-PEDS1, NCT04396236 / 2019-004378-24: A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Recruiting
3
1633
Europe, Japan, US, RoW
Lasmiditan, LY573144, Placebo
Eli Lilly and Company
Migraine
01/25
01/25
PIONEER-PEDS2, NCT04396574 / 2019-004379-38: A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Recruiting
3
1000
Europe, Japan, US, RoW
Lasmiditan, LY573144
Eli Lilly and Company
Migraine
03/26
03/26
NCT06754722: Decentralized Clinical Trial of Effectiveness of EnergyPoints App in Cancer Survivors

Not yet recruiting
N/A
180
US
App to guide self-acupressure
5 Point App, Inc.
Cancer-related Problem/condition, Fatigue in Cancer Survivors, Sleep Disturbances, Health-related Quality of Life
10/26
12/26
PREDICT, NCT03448926: The Registry:

Recruiting
N/A
3000
US
Treatment Recommendation Surveys, 7-gene biosignature
PreludeDx, University of South Florida
DCIS
12/25
12/35
NCT06087224: The TELENEO Trial: a Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

Recruiting
N/A
947
Canada, US
Teleneonatology
Mayo Clinic, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Death; Neonatal, Morbidity;Newborn
02/29
05/29
Wegner, Rodney E
NRG-CC009, NCT04804644: Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Recruiting
3
200
Canada, US
Memantine Hydrochloride, Ebixia, Namenda, Neurocognitive Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy
NRG Oncology, National Cancer Institute (NCI)
Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
07/28
07/30
S22-11168, NCT06359379: Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Recruiting
2
54
US
Ropidoxuridine, 5-iodo-2-pyrimidinone-2'-deoxyribose
Shuttle Pharmaceuticals, Inc.
Glioblastoma, IDH-wildtype
08/26
02/27
NCT05341739: A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases

Recruiting
N/A
20
US
Pre-operative Stereotactic Radiosurgery
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), Elekta Limited
Brain Metastases, Adult
07/24
12/24
NCT01885299: RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

Recruiting
N/A
50000
US
SRS/SBRT
The Radiosurgery Society, VisionTree
Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia
12/30
12/30
Arai, Yoshio
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22
Quinn, Annette E
NCT01360606: Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Completed
N/A
9
US
Stereotactic Body Radiation Therapy, CyberKnife, Trilogy, True Beam, Radiosurgery
Susannah Ellsworth
Liver Metastases
07/18
02/21
Benoit, Ronald M
NCT03665922: Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer

Active, not recruiting
N/A
39
US
BroccoMax®, Placebo, Microcrystalline cellulose
University of Pittsburgh, National Cancer Institute (NCI)
Prostate Cancer
12/24
12/24
Davies, Benjamin
RECEDE, NCT04631471 / 2017-004856-41: Regeneration in Cervical Degenerative Myelopathy

Recruiting
3
400
Europe
Ibudilast, Cervical decompressive surgery, Matching placebo
Cambridge University Hospitals NHS Foundation Trust, NIHR
Myelopathy, Spinal Cord Diseases
09/26
09/26
S1802, NCT03678025: Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Recruiting
3
1273
Europe, US, RoW
Abiraterone, CB 7598, Bicalutamide, Casodex, Cosudex, ICI 176,334, ICI 176334, Degarelix, FE200486, Firmagon, Docetaxel, Docecad, RP56976, Taxotere, Taxotere Injection Concentrate, Flutamide, 4'-Nitro-3'-trifluoromethylisobutyranilide, Apimid, Cebatrol, Chimax, Cytomid, Drogenil, Euflex, Eulexine, Flucinom, Flucinome, Flugerel, Fluken, Flulem, FLUT, Fluta-Gry, Flutabene, Flutacan, Flutamex, Flutamin, Flutan, Flutaplex, Fugerel, Grisetin, Niftolide, Oncosal, Profamid, Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-, Prostacur, Prostadirex, Prostica, Prostogenat, SCH 13521, Tafenil, Tecnoflut, Testotard, Goserelin Acetate, ZDX, Zoladex, Histrelin Acetate, Supprelin, Vantas, Leuprolide Acetate, A-43818, Abbott 43818, Abbott-43818, Carcinil, Depo-Eligard, Eligard, Enanton, Enantone, Enantone-Gyn, Ginecrin, LEUP, Leuplin, Leuprorelin Acetate, Lucrin, Lucrin Depot, Lupron, Lupron Depot, Lupron Depot-3 Month, Lupron Depot-4 Month, Lupron Depot-Ped, Procren, Procrin, Prostap, TAP-144, Trenantone, Uno-Enantone, Viadur, Nilutamide, Anandron, Nilandron, RU-23908, Orchiectomy, Castration, Male Castration, Male Gonadectomy, orchidectomy, Prednisone, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Adasone, Cortancyl, Dacortin, DeCortin, Decortisyl, Decorton, Delta 1-Cortisone, Delta-Dome, Deltacortene, Deltacortisone, Deltadehydrocortisone, Deltasone, Deltison, Deltra, Econosone, Lisacort, Meprosona-F, Metacortandracin, Meticorten, Ofisolona, Orasone, Panafcort, Panasol-S, Paracort, PRED, Predicor, Predicorten, Prednicen-M, Prednicort, Prednidib, Prednilonga, Predniment, Prednisonum, Prednitone, Promifen, Servisone, SK-Prednisone, Quality-of-Life Assessment, Quality of Life Assessment, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, irradiation, Radiation, Radiotherapeutics, RADIOTHERAPY, RT, Therapy, Radiation, Radical Prostatectomy, Prostatovesiculectomy, Triptorelin, 6-D-Tryptophan-LH-RH, 6-D-Tryptophanluteinizing Hormone-releasing Factor, AY-25650, CL-118,532, Decapeptyl, Detryptoreline
SWOG Cancer Research Network, National Cancer Institute (NCI)
Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
04/28
10/31
NCT03665922: Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer

Active, not recruiting
N/A
39
US
BroccoMax®, Placebo, Microcrystalline cellulose
University of Pittsburgh, National Cancer Institute (NCI)
Prostate Cancer
12/24
12/24
IMAGE-DCM, NCT05242666: Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy

Recruiting
N/A
100
Europe
3T MR Imaging of the cervical spinal cord, Positron Emission Tomography using [11C]PIB, 3T MR Imaging of the Brain, 7T MR Imaging of the Spinal Cord
Cambridge University Hospitals NHS Foundation Trust, National Institute for Health Research, United Kingdom, Wolfson Brain Imaging Centre
Cervical Spondylosis With Myelopathy, Degenerative Cervical Myelopathy
02/25
02/25
Lee, Kenneth
NCT01843504: Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy

Completed
2
29
US
platelet rich plasma, saline
University of Wisconsin, Madison
Chronic Patellar Tendinopathy, Chronic PT
02/24
02/24
NCT04794335: Visceral Afferents

Withdrawn
N/A
224
US
University of Pittsburgh, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Inflammatory Bowel Diseases
04/25
04/25
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26
Burton, Steve
NCT01345552: Radiosurgery for Patients Recurrent Oligometastatic Disease

Completed
2
173
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam
Steven Burton
Recurrent Oligometastatic Disease
10/20
10/22
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22
NCT02054689: Fractionated Stereotactic Radiosurgery for Large Brain Metastases

Active, not recruiting
1
20
US
Fractionated Stereotactic Radiosurgery, SRS, SBRT, CyberKnife, Trilogy, True Beam, Radiosurgery
Steven Burton
Large Brain Mets
11/17
04/24
Clump, David A
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
NCT02514915: Pre-operative Stereotactic Radiosurgery Followed by Resection for Brain Metastases

Completed
2
24
US
Stereotactic Radiosurgery
Christopher Wilke
Malignant Neoplasm Brain
07/21
07/21
MIT-001, NCT04651634: for Prevention of CCRT-Induced OM in HNSCC Patients

Recruiting
2
60
US, RoW
MIT-001 plus CCRT
MitoImmune Therapeutics
Head and Neck Squamous Cell Carcinoma, Oral Mucositis
04/24
12/24
KEYSTROKE, NCT03546582: SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma

Recruiting
2
102
Canada, US
Pembrolizumab, Keytruda, Stereotactic Body Radiation Therapy (SBRT), SBRT
RTOG Foundation, Inc., Merck Sharp & Dohme LLC
Head and Neck Squamous Cell Carcinoma (HNSCC)
07/27
07/29
NCT02734537: Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Recruiting
2
189
US
Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Intensity-Modulated Radiation Therapy, IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis
ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)
Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant, Lip and Oral Cavity Squamous Cell Carcinoma, p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma, Stage III Hypopharyngeal Carcinoma AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oral Cavity Verrucous Carcinoma, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IVA Hypopharyngeal Carcinoma AJCC v8, Stage IVA Laryngeal Cancer AJCC v8, Stage IVA Lip and Oral Cavity Cancer AJCC v8, Stage IVA Oral Cavity Verrucous Carcinoma, Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
12/27
12/27
NCT02054689: Fractionated Stereotactic Radiosurgery for Large Brain Metastases

Active, not recruiting
1
20
US
Fractionated Stereotactic Radiosurgery, SRS, SBRT, CyberKnife, Trilogy, True Beam, Radiosurgery
Steven Burton
Large Brain Mets
11/17
04/24
NCT01360606: Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Completed
N/A
9
US
Stereotactic Body Radiation Therapy, CyberKnife, Trilogy, True Beam, Radiosurgery
Susannah Ellsworth
Liver Metastases
07/18
02/21
PREDICT, NCT03448926: The Registry:

Recruiting
N/A
3000
US
Treatment Recommendation Surveys, 7-gene biosignature
PreludeDx, University of South Florida
DCIS
12/25
12/35
Karlovits, Brian J
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
Engh, Johnathan
NCT02054689: Fractionated Stereotactic Radiosurgery for Large Brain Metastases

Active, not recruiting
1
20
US
Fractionated Stereotactic Radiosurgery, SRS, SBRT, CyberKnife, Trilogy, True Beam, Radiosurgery
Steven Burton
Large Brain Mets
11/17
04/24
Amankulor, Nduka
ImmuneSense, NCT04485949: A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

Active, not recruiting
2
93
US
IGV-001 Cell Immunotherapy, Placebo, Standard of Care (SOC): Radiation Therapy, SOC: Temozolomide
Imvax
Glioblastoma
01/25
07/27
NCT02054689: Fractionated Stereotactic Radiosurgery for Large Brain Metastases

Active, not recruiting
1
20
US
Fractionated Stereotactic Radiosurgery, SRS, SBRT, CyberKnife, Trilogy, True Beam, Radiosurgery
Steven Burton
Large Brain Mets
11/17
04/24
LIBERATE, NCT05383872: Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects with GlioBlastoma Brain Tumors

Recruiting
N/A
57
Canada, US
Focused Ultrasound (Exablate Model 4000)
InSightec
Glioblastoma, Glioma, Liquid Biopsy
12/24
03/25
Kubicek, Gregory
METIS, NCT02831959: Pivotal, Open-label, Randomized Study of Radiosurgery with or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC).

Completed
3
298
Europe, Canada, US, RoW
NovoTTF-200M device, Best Standard of Care
NovoCure GmbH
Brain Metastases from Non-small Cell Lung Cancer (NSCLC)
11/24
11/24
SELECT, NCT05451004: SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

Recruiting
3
510
Canada, US
Lymphatic Mapping with SPECT-CT, Ipsilateral and Contralateral Neck
Canadian Cancer Trials Group, Alliance for Clinical Trials in Oncology, Eastern Cooperative Oncology Group, NRG Oncology, SWOG Cancer Research Network
Oropharyngeal Cancer
08/30
08/31
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22
NCT04870762: Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

Recruiting
2
119
US
Best Practice, standard of care, standard therapy, Medical Device Usage and Evaluation
M.D. Anderson Cancer Center
Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm, Maxillary Sinus Carcinoma, Nasal Cavity Carcinoma, Oral Cavity Carcinoma, Tongue Carcinoma, Tonsillar Carcinoma
12/26
12/26
MelPORT, NCT04594187: Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma

Recruiting
2
168
US
Immunotherapy, Immunological, Immunological Therapy, Immunologically Directed Therapy, Quality-of-Life Assessment, Quality of Life Assessment, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
M.D. Anderson Cancer Center
Melanoma
02/25
02/25
Holeva, Karen
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
NCT02128906: Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design

Recruiting
2
120
US
Cisplatin, Platinol, IMRT, Docetaxel, Taxotere, Cetuximab, Erbitux
Christopher Wilke
Squamous Cell Carcinoma
12/30
12/30
STEEL, NCT03809000: A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery

Active, not recruiting
2
188
Canada, US
Radiation Therapy, RT, Image-Guided Radiation Therapy (IGRT), Radiotherapy, Enzalutamide, Xtandi®, Bicalutamide, Casodex®, GnRH analog, Gonadotropin-releasing hormone analog, Lupron®, leuprolide acetate, goserelin acetate, Eligard™, Viadur™, Zoladex®, Trelstar®
RTOG Foundation, Inc., Pfizer, Astellas Pharma Inc
Prostate Cancer
04/23
09/29
KEYSTROKE, NCT03546582: SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma

Recruiting
2
102
Canada, US
Pembrolizumab, Keytruda, Stereotactic Body Radiation Therapy (SBRT), SBRT
RTOG Foundation, Inc., Merck Sharp & Dohme LLC
Head and Neck Squamous Cell Carcinoma (HNSCC)
07/27
07/29
NCT02054689: Fractionated Stereotactic Radiosurgery for Large Brain Metastases

Active, not recruiting
1
20
US
Fractionated Stereotactic Radiosurgery, SRS, SBRT, CyberKnife, Trilogy, True Beam, Radiosurgery
Steven Burton
Large Brain Mets
11/17
04/24
Ohr, James
NCT02057107: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Completed
2
40
US
SBRT, Radiosurgery, Stereotactic radiosurgery, CyberKnife, True Beam, Trilogy, Cetuximab, Erbitux, Docetaxel, Taxotere
Heath Skinner
Previously-Irradiated, Squamous Cell Carcinoma of the Head and Neck Cancer
03/19
12/19
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation

Terminated
2
24
US
Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy
Steven Burton
Oligometastatic Disease
05/22
10/22

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