| Michel, Patrik |
| Active, not recruiting | 3 | 610 | Europe | IMP Levodopa 100mg/Carbidopa 25mg, Matching placebo | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Acute Stroke, Stroke Rehabilitation | 08/24 | 06/29 | | |
NCT04895462: Acute Revascularization Treatment in Ischemic Stroke Patients With COVID-19 |
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| Completed | N/A | 15128 | Europe | | Centre Hospitalier Universitaire Vaudois, Larissa University Hospital, Society of Vascular and Interventional Neurology, Hospital de Egas Moniz | Ischemic Stroke, Covid19 | 08/21 | 10/21 | | |
ELAN, NCT03148457: Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial |
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| Completed | N/A | 2013 | Europe, Japan, RoW | Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®), Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®) | Insel Gruppe AG, University Hospital Bern | Ischaemic Stroke | 12/22 | 05/23 | | |
DO-IT Cohort, NCT06556446: Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants |
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| Recruiting | N/A | 2800 | Europe, Canada, RoW | Tenecteplase and Alteplase | Insel Gruppe AG, University Hospital Bern, Swiss Stroke Trialist Association, Swiss Stroke Registry | Ischemic Stroke | 03/26 | 12/26 | | |
DISTAL, NCT05029414: EnDovascular Therapy Plus Best Medical Treatment (BMT) Versus BMT Alone for MedIum VeSsel Occlusion sTroke |
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| Active, not recruiting | N/A | 543 | Europe, RoW | Endovascular Therapy | University Hospital, Basel, Switzerland, Swiss National Fund for Scientific Research, Stryker Neurovascular, Penumbra Inc., Medtronic, Phenox GmbH, Rapid Medical, Gottfried und Julia Bangerter-Rhyner-Stiftung | Acute Ischemic Stroke | 10/24 | 06/25 | | |
| Demartines, Nicolas |
| Active, not recruiting | N/A | 144 | Europe | Early enteral nutrition | University of Lausanne Hospitals | Pancreaticoduodenectomy, Malnutrition, Postoperative Complications | 02/25 | 02/25 | | |
| Piquilloud, Lise |
| Completed | N/A | 40 | Europe | ASV ventilation | University of Lausanne Hospitals | Mechanical Ventilation | 12/23 | 12/23 | | |
| Albrecht, Eric |
| Completed | 4 | 60 | Europe | Ropivacaine 0.75% Injectable Solution | Eric Albrecht | Arthroscopic Surgery of the Shoulder, Extrafascial Interscalene Plexus Brachial Block | 11/23 | 11/23 | | |
TwoDex, NCT05389852: Analgesic Efficacy of Intravenous Dexmedetomidine for Supraclavicular Plexus Block |
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| Completed | 4 | 100 | Europe | Dexmedetomidine, Dexdor | Hôpital du Valais | Surgery | 02/24 | 02/24 | | |
| Recruiting | 4 | 100 | Europe | ultrasound-guided Transversus Thoracis Muscle Plane Block | Hôpital du Valais | Postoperative Pain | 03/26 | 04/26 | | |
NCT05728294: Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy |
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| Completed | N/A | 50 | Europe | Femoral nerve block with ropivacaine 0.5%, 20 ml, Sciatic nerve block with ropivacaine 0.5%, 20 ml | Centre Hospitalier Universitaire Vaudois | Postoperative Pain | 10/22 | 03/23 | | |
NCT03683342: Comparison of Analgesic Duration of Popliteal Block Versus Ankle Block in Patients Undergoing Forefoot Surgery |
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| Completed | N/A | 60 | Europe | Ankle Block, Sciatic nerve block | Centre Hospitalier Universitaire Vaudois | Pain, Postoperative | 11/22 | 12/22 | | |
| Completed | N/A | 141 | Europe | Lung ultrasound | Eric Albrecht | Atelectasis | 12/22 | 12/22 | | |
| Completed | N/A | 100 | Europe | Mandibular advancement device | Centre Hospitalier Universitaire Vaudois | Peri-operative Medicine, Sleep Apnea | 10/23 | 10/23 | | |
NCT03454191: Efficacy of Erector Spinae Plane Block for Postoperative Analgesia in Adult Patients Undergoing Thoracoscopy |
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| Terminated | N/A | 10 | Europe | Erector spinae plane block, No injection | Eric Albrecht | Pain, Postoperative | 10/23 | 10/23 | | |
TIPACK, NCT05303233: IPACK or Selective Tibial Nerve Block for ACL Reconstruction with an Adductor Canal Block |
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| Active, not recruiting | N/A | 80 | Europe | Selective tibial nerve block, IPACK | Centre Hospitalier Universitaire Vaudois | Analgesia | 11/24 | 08/25 | | |
| Oddo, Mauro |
TTM-2, NCT02908308: Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest |
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| Completed | N/A | 1900 | Europe, US, RoW | Targeted temperature management to 33°C, Standard care with early treatment of fever | Helsingborgs Hospital, Lund University, Region Skåne - Skånevård SUND, Copenhagen Trial Unit, Center for Clinical Intervention Research, Clinical Trials Sweden, Forum South, Integrated Biobank of Luxembourg | Out-of-hospital Cardiac Arrest | 06/22 | 12/22 | | |
| Eicher, Manuela |
IePRO, NCT05530187: ePRO-based Model of Care to Manage and Monitoring Symptoms of Cancer Patients Treated With Immune Checkpoint Inhibitors |
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| Recruiting | 2 | 198 | Europe | Electronic Patient-reported Outcomes-based Model of Care | Manuela Eicher | Patient Reported Outcome Measures, Patient Safety | 11/23 | 11/23 | | |
| Corcione, Nadia |
| Recruiting | N/A | 150 | Europe | Bronchoscopy | University of Milan | Hemoptysis | 10/24 | 10/25 | | |
| Recruiting | N/A | 30 | Europe | High flow nasal cannula, nebulized normal saline | Cardarelli Hospital | Airway Obstruction, Respiratory Infection, Mucus; Plug | 11/24 | 12/24 | | |
| Méan, Marie |
SAFE-SSPE, NCT04263038: Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism |
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| Recruiting | 4 | 276 | Europe, Canada | Rivaroxaban, Placebo | Drahomir Aujesky, University of Bern, Schweizerischer Nationalfonds, Leiden University Medical Center, The Ottawa Hospital, Bayer | Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases, Cardiovascular Diseases, Respiratory Tract Diseases, Venous Thromboembolism, Anticoagulant-induced Bleeding, Bleeding | 05/26 | 05/26 | | |
| Recruiting | N/A | 1800 | Europe | Statin discontinuation, Intervention arm | Insel Gruppe AG, University Hospital Bern, University of Bern | Statin Treatment for Primary Prevention | 11/26 | 11/26 | | |
| Bochatay, Mallory Moret |
SAFE-SSPE, NCT04263038: Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism |
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| Recruiting | 4 | 276 | Europe, Canada | Rivaroxaban, Placebo | Drahomir Aujesky, University of Bern, Schweizerischer Nationalfonds, Leiden University Medical Center, The Ottawa Hospital, Bayer | Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases, Cardiovascular Diseases, Respiratory Tract Diseases, Venous Thromboembolism, Anticoagulant-induced Bleeding, Bleeding | 05/26 | 05/26 | | |
| Beun, Ludovic |
TIPACK, NCT05303233: IPACK or Selective Tibial Nerve Block for ACL Reconstruction with an Adductor Canal Block |
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| Active, not recruiting | N/A | 80 | Europe | Selective tibial nerve block, IPACK | Centre Hospitalier Universitaire Vaudois | Analgesia | 11/24 | 08/25 | | |
| d'Aische, Marta Szyszko du Bois |
PIPACK, NCT06179641: Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty |
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| Recruiting | N/A | 100 | Europe | Selective tibial nerve block, IPACK block | Centre Hospitalier Universitaire Vaudois | Analgesia, Arthropathy of Knee, Postoperative Pain | 07/25 | 07/25 | | |
PENGIT, NCT06317870: Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty |
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| Recruiting | N/A | 80 | Europe | Intrathecal morphine, Pericapsular nerve group block (PENG) | Centre Hospitalier Universitaire Vaudois | Analgesia, Hip Arthropathy, Post Operative Pain | 01/27 | 05/27 | | |
