| Jones, Grant |
| Recruiting | N/A | 2500 | US | | Carolyn M Hettrich, University of Michigan, University of California, San Francisco, University of Kentucky, Hospital for Special Surgery, New York, University of Colorado, Denver, Ohio State University, Washington University School of Medicine, Orthopedic Institute, Sioux Falls, SD, Vanderbilt University, Brigham and Women's Hospital | Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region | 12/22 | 12/42 | | |
NCT05746312: Music-based Mindfulness Intervention for Elevated Race-based Anxiety in the Black Community |
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| Completed | N/A | 8 | US | healing attempt | Harvard University | Anxiety | 01/23 | 01/23 | | |
NCT03985839: Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip |
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| Completed | N/A | 299 | US | MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor | Smith & Nephew, Inc. | Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability, SLAP Lesion, Rotator Cuff Tears | 08/24 | 08/24 | | |
| O'Neill, Sean |
NCT04861714: Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR) |
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| Active, not recruiting | N/A | 75 | US | Regeneten, Standard repair | Ohio State University, Smith & Nephew, Inc. | Arthroplasty, Replacement, Shoulder | 12/24 | 04/25 | | |
| Flanigan, David |
NCT03219307: NOVOCART 3D Treatment Following Microfracture Failure |
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| Recruiting | 3 | 30 | US | NOVOCART 3D | Aesculap Biologics, LLC | Articular Cartilage Defect | 12/25 | 12/28 | | |
NCT01957722: NOVOCART®3D for Treatment of Articular Cartilage of the Knee |
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| Active, not recruiting | 3 | 233 | Canada, US | Microfracture, NOVOCART 3D | Aesculap Biologics, LLC | Articular Cartilage of the Femoral Condyle Between 2-6cm2 | 12/25 | 12/27 | | |
NCT04744402: Phase 2 Clinical Trial of CartiLife® in the United States |
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| Recruiting | 2 | 25 | US | Autologous Chondrocyte Implantation (CartiLife®), CCP-ACI | Biosolution Co., Ltd. | Articular Cartilage Defect, Articular Cartilage Degeneration | 12/23 | 12/23 | | |
| Active, not recruiting | N/A | 81 | US | Calypso Knee System (Implantable Shock Absorber), MISHA® Knee System | Moximed | Osteoarthritis, Knee | 01/22 | 03/25 | | |
| Active, not recruiting | N/A | 81 | Europe | Calypso Knee System (Implantable Shock Absorber), MISHA(R) Knee System | Moximed | Osteoarthritis, Knee | 01/22 | 03/25 | | |
| Active, not recruiting | N/A | 13 | Europe, Canada, US | Episealer Knee System, Microfracture | Episurf Medical Inc., MCRA | Degenerative Lesion of Articular Cartilage of Knee | 06/26 | 06/28 | | |
| Active, not recruiting | N/A | 66 | US | PET scan, MRI scan | University of Cincinnati | ACL Injury | 12/24 | 12/24 | | |
| Active, not recruiting | N/A | 200 | Europe, US, RoW | Hyalofast, Microfracture | Anika Therapeutics, Inc. | Defect of Articular Cartilage | 06/25 | 06/26 | | |
BEAR-MOON, NCT03776162: A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction |
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| Recruiting | N/A | 200 | US | ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR) | The Cleveland Clinic, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Miach Orthopaedics | Anterior Cruciate Ligament Tear | 05/27 | 05/27 | | |
| Recruiting | N/A | 100 | US | IntraOsseous BioPlasty® (IOBP®) Surgical Technique into the knee | Arthrex, Inc. | Subchondral Cyst | 05/27 | 05/27 | | |
| Active, not recruiting | N/A | 120 | US | MISHA Knee System, Implantable Shock Absorber (ISA) | Moximed | Osteo Arthritis Knee | 06/30 | 07/30 | | |
| Keller, Michael |
NCT05492851: Trial Comparing Three Single Dose Injections for Knee Osteoarthritis |
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| Terminated | 4 | 6 | US | Zilretta, Synvisc-One 48 MG in 6 ML Prefilled Syringe, Monovisc 88 MG Per 4 ML Prefilled Syringe | Ohio State University | Osteoarthritis, Knee | 01/23 | 01/23 | | |
| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | Ralinepag, APD811, Placebo | United Therapeutics | PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease | 12/25 | 12/25 | | |
ACES, NCT03475212: Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation |
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| Active, not recruiting | 1/2 | 60 | US | Virus Specific T-cell (VST) infusion | Michael Pulsipher, MD | Cytomegalovirus Infections, Adenovirus Infection, EBV Infection | 01/24 | 02/24 | | |
NCT05880888: Investigating the Clinical Impact of a Novel Adipose Allograft Matrix on Knee Fat Pad Impingement Treatment |
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| Active, not recruiting | 1 | 5 | US | Renuva | Ohio State University | Fat Pad Syndrome | 12/24 | 12/24 | | |
NCT03485963: HIV-1 Specific T -Cells (HST-NEETs) for HIV-Infected Individuals |
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| Active, not recruiting | 1 | 7 | US | HST-NEETs | Catherine Bollard | HIV Infections | 06/24 | 12/24 | | |
NCT04248192: Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST) |
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| Recruiting | 1 | 8 | US | DD HST-NEETs | Catherine Bollard | HIV-Infected Individuals | 09/24 | 04/25 | | |
NCT03180216: T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantation |
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| Active, not recruiting | 1 | 32 | US | Virus Specific T cells (VSTs) | Children's National Research Institute | Viral Infections, Bone Marrow Transplant Infection | 03/26 | 11/26 | | |
ATLANTIC, NCT04691622: Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts |
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| Recruiting | 1 | 48 | US | Norovirus -specific T-cell (NST) therapy | Children's National Research Institute | Viral Infection, Hematopoietic Stem Cell Transplantation (HSCT), Primary Immunodeficiency Disorders (PID) | 08/25 | 10/26 | | |
TONI, NCT05141058: T CELL THERAPY OPPOSING NOVEL COVID-19 INFECTION IN IMMUNOCOMPROMISED PATIENTS |
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| Recruiting | 1 | 24 | US | Coronavirus-specific T cell (CST) | Children's National Research Institute | SARS-CoV-2 Infection | 11/25 | 12/27 | | |
NCT03878069: Registry Study of Revcovi Treatment in Patients With ADA-SCID |
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| Completed | N/A | 32 | US | elapegademase-lvlr, Revcovi | Chiesi Farmaceutici S.p.A. | Adenosine Deaminase Severe Combined Immunodeficiency | 01/23 | 01/23 | | |
NCT04861714: Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR) |
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| Active, not recruiting | N/A | 75 | US | Regeneten, Standard repair | Ohio State University, Smith & Nephew, Inc. | Arthroplasty, Replacement, Shoulder | 12/24 | 04/25 | | |
NCT05492396: Evaluation of Healing Following Open Gluteus Medius Repair With Biointegrative Implant |
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| Recruiting | N/A | 30 | US | Standard gluteus medius repair with Tapestry Biointegrative implant | Ohio State University | Hip Injuries, Tendon Injuries, Orthopedic Procedures | 06/25 | 12/25 | | |
NCT06388993: Marrow Cellution™ vs. Traditional BMA Harvest Project |
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| Recruiting | N/A | 6 | US | Bone Marrow Collection | Ohio State University | Hip Arthropathy, Avascular Necrosis of Bone, Subchondral Cysts | 12/24 | 03/25 | | |
ARC, NCT03295994: Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears |
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| Active, not recruiting | N/A | 189 | US | Operative, Non-Operative | University of Michigan, Patient-Centered Outcomes Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Rotator Cuff Tear | 02/25 | 11/26 | | |
| Recruiting | N/A | 20000 | US | | National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Mental Health (NIMH) | Atopy, Primary Immunodeficiency, Autoimmunity, Autoinflammation | 12/29 | 12/29 | | |
NCT03394053: The Mechanistic Biology of Primary Immunodeficiency Disorders |
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| Recruiting | N/A | 2500 | US | | National Institute of Allergy and Infectious Diseases (NIAID) | Primary Immunodeficiency Disorders | 12/29 | 12/42 | | |
| Miller, Timothy E |
| Terminated | 3 | 489 | Europe, Canada, US, RoW | Reldesemtiv, Placebo | Cytokinetics | Amyotrophic Lateral Sclerosis | 07/23 | 07/23 | | |
| No Longer Available | N/A | | US | Trehalose, SLS-005 Intravenous Trehalose Injection 90.5 mg/mL | Seelos Therapeutics, Inc., Massachusetts General Hospital, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) | Amyotrophic Lateral Sclerosis | | | | |
| Recruiting | N/A | 1000 | US | MicroVention Mechanical Thrombectomy Devices as first-line treatment | Microvention-Terumo, Inc. | Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic | 12/25 | 12/25 | | |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
| Magnussen, Robert A |
| Recruiting | 2 | 512 | US | Metformin, Glumetza, Fortamet, Glucophage extended release (XR), Placebo | Brigham and Women's Hospital, Arthritis Foundation | Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear | 12/28 | 12/29 | | |
| Active, not recruiting | N/A | 66 | US | PET scan, MRI scan | University of Cincinnati | ACL Injury | 12/24 | 12/24 | | |
| Active, not recruiting | N/A | 120 | US | MISHA Knee System, Implantable Shock Absorber (ISA) | Moximed | Osteo Arthritis Knee | 06/30 | 07/30 | | |
| Kaeding, Christopher |
| Active, not recruiting | N/A | 66 | US | PET scan, MRI scan | University of Cincinnati | ACL Injury | 12/24 | 12/24 | | |
BEAR-MOON, NCT03776162: A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction |
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| Recruiting | N/A | 200 | US | ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR) | The Cleveland Clinic, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Miach Orthopaedics | Anterior Cruciate Ligament Tear | 05/27 | 05/27 | | |
| Bishop, Julie Y |
| Recruiting | N/A | 2500 | US | | Carolyn M Hettrich, University of Michigan, University of California, San Francisco, University of Kentucky, Hospital for Special Surgery, New York, University of Colorado, Denver, Ohio State University, Washington University School of Medicine, Orthopedic Institute, Sioux Falls, SD, Vanderbilt University, Brigham and Women's Hospital | Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region | 12/22 | 12/42 | | |
NCT04861714: Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR) |
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| Active, not recruiting | N/A | 75 | US | Regeneten, Standard repair | Ohio State University, Smith & Nephew, Inc. | Arthroplasty, Replacement, Shoulder | 12/24 | 04/25 | | |
NCT03985839: Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip |
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| Completed | N/A | 299 | US | MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor | Smith & Nephew, Inc. | Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability, SLAP Lesion, Rotator Cuff Tears | 08/24 | 08/24 | | |
OASIS, NCT04809064: Open Versus Arthroscopic Stabilization of Shoulder Instability with Subcritical Bone Loss: the Trial |
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| Recruiting | N/A | 400 | US | Arthroscopic Bankart repair procedure, Open Bankart, Latarjet, Post-Operative Rehabilitation | University of Pittsburgh, Walter Reed National Military Medical Center | Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation | 09/27 | 09/27 | | |
| Recruiting | N/A | 200 | US | Shoulder iD™ Primary Reversed Glenoid, Patient-Matched Primary Reversed Glenoid | Stryker Trauma and Extremities | Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Fracture, Humeral, Traumatic Arthritis of Right Shoulder Region (Diagnosis), Shoulder Deformity | 12/27 | 12/35 | | |
| Baria, Michael |
NCT05492851: Trial Comparing Three Single Dose Injections for Knee Osteoarthritis |
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| Terminated | 4 | 6 | US | Zilretta, Synvisc-One 48 MG in 6 ML Prefilled Syringe, Monovisc 88 MG Per 4 ML Prefilled Syringe | Ohio State University | Osteoarthritis, Knee | 01/23 | 01/23 | | |
NCT05880888: Investigating the Clinical Impact of a Novel Adipose Allograft Matrix on Knee Fat Pad Impingement Treatment |
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| Active, not recruiting | 1 | 5 | US | Renuva | Ohio State University | Fat Pad Syndrome | 12/24 | 12/24 | | |
NCT04351087: Microfragmented Adipose Tissue Versus Platelet-rich Plasma for Knee Osteoarthritis: a Randomized Comparative Trial |
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| Completed | N/A | 79 | US | Platelet Rich Plasma, Microfragmented adipose tissue | Ohio State University | Osteoarthritis, Knee, Microfragmented Adipose Tissue, Platelet-Rich Plasma | 07/22 | 07/22 | | |
NCT04440189: Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis |
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| Recruiting | N/A | 124 | US | GID SVF-2 Device System | GID BIO, Inc. | Osteoarthritis, Knee | 12/23 | 12/24 | | |
| Pedroza, Angela |
NCT06000410: A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee |
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| Recruiting | 3 | 474 | US | Amniotic Suspension Allograft, Placebo | Organogenesis | Knee Osteoarthritis | 09/25 | 03/26 | | |
NCT04744402: Phase 2 Clinical Trial of CartiLife® in the United States |
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| Recruiting | 2 | 25 | US | Autologous Chondrocyte Implantation (CartiLife®), CCP-ACI | Biosolution Co., Ltd. | Articular Cartilage Defect, Articular Cartilage Degeneration | 12/23 | 12/23 | | |
NCT05079035: Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA |
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| Active, not recruiting | 2 | 90 | US | TTAX03, Saline | BioTissue Holdings, Inc | Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis | 03/25 | 03/25 | | |
NCT03985839: Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip |
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| Completed | N/A | 299 | US | MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor | Smith & Nephew, Inc. | Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability, SLAP Lesion, Rotator Cuff Tears | 08/24 | 08/24 | | |
| Recruiting | N/A | 200 | US | Shoulder iD™ Primary Reversed Glenoid, Patient-Matched Primary Reversed Glenoid | Stryker Trauma and Extremities | Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Fracture, Humeral, Traumatic Arthritis of Right Shoulder Region (Diagnosis), Shoulder Deformity | 12/27 | 12/35 | | |
| Neviaser, Andrew |
| Recruiting | N/A | 2500 | US | | Carolyn M Hettrich, University of Michigan, University of California, San Francisco, University of Kentucky, Hospital for Special Surgery, New York, University of Colorado, Denver, Ohio State University, Washington University School of Medicine, Orthopedic Institute, Sioux Falls, SD, Vanderbilt University, Brigham and Women's Hospital | Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region | 12/22 | 12/42 | | |
NCT04861714: Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR) |
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| Active, not recruiting | N/A | 75 | US | Regeneten, Standard repair | Ohio State University, Smith & Nephew, Inc. | Arthroplasty, Replacement, Shoulder | 12/24 | 04/25 | | |
NCT03985839: Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip |
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| Completed | N/A | 299 | US | MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor | Smith & Nephew, Inc. | Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability, SLAP Lesion, Rotator Cuff Tears | 08/24 | 08/24 | | |
ARC, NCT03295994: Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears |
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| Active, not recruiting | N/A | 189 | US | Operative, Non-Operative | University of Michigan, Patient-Centered Outcomes Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Rotator Cuff Tear | 02/25 | 11/26 | | |
| Cvetanovich, Gregory |
NCT04861714: Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR) |
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| Active, not recruiting | N/A | 75 | US | Regeneten, Standard repair | Ohio State University, Smith & Nephew, Inc. | Arthroplasty, Replacement, Shoulder | 12/24 | 04/25 | | |
NCT03985839: Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip |
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| Completed | N/A | 299 | US | MICRORAPTOR™ REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless REGENESORB™ Suture Anchor, MICRORAPTOR™ Knotless PEEK Suture Anchor | Smith & Nephew, Inc. | Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions, Anterior Shoulder Instability, SLAP Lesion, Rotator Cuff Tears | 08/24 | 08/24 | | |
ARC, NCT03295994: Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears |
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| Active, not recruiting | N/A | 189 | US | Operative, Non-Operative | University of Michigan, Patient-Centered Outcomes Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Rotator Cuff Tear | 02/25 | 11/26 | | |
| Recruiting | N/A | 1500 | US | NA (not an interventional study) | University of Texas Southwestern Medical Center, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Rotator Cuff Tears | 12/26 | 12/31 | | |
| Recruiting | N/A | 200 | US | Shoulder iD™ Primary Reversed Glenoid, Patient-Matched Primary Reversed Glenoid | Stryker Trauma and Extremities | Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Fracture, Humeral, Traumatic Arthritis of Right Shoulder Region (Diagnosis), Shoulder Deformity | 12/27 | 12/35 | | |
