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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Puskas, John D
NCT01757665: ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE)	Active, not recruiting	N/A	777	Europe, Canada, US	Edwards Aortic and Mitral Bioprostheses Models 11000A and 11000M	Edwards Lifesciences	Aortic Stenosis, Mitral Stenosis, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Heart Failure	08/17	08/26
VEST Pivotal, NCT03209609: VEST Venous Graft External Support Pivotal Study	Active, not recruiting	N/A	224	Canada, US	VEST, Coronary artery bypass vein grafts	Vascular Graft Solutions Ltd., International Center for Health Outcomes and Innovation Research	Coronary Artery Disease	09/20	06/24
PROACT, NCT00291525: Randomized On-X Anticoagulation Trial	Active, not recruiting	N/A	1200	Canada, US	On-X valve using reduced anticoagulation, On-X Prosthetic Heart Valve, On-X Valve with Standard warfarin Therapy	On-X Life Technologies, Inc., Clinipace Worldwide, Acelis Connected Health, WCG IRB, Avania	Heart Valve Disease	12/22	12/22
Idrissi, Katharine
REVERSE-HF, NCT05318105: Ultrafiltration Versus IV Diuretics in Worsening Heart Failure	Recruiting	N/A	372	US	Aquadex Smartflow® System, IV Loop Diuretics	Nuwellis, Inc.	Heart Failure (for Example, Fluid Overload)	07/25	10/25