| Park, Haeseong |
CA209-76L, NCT04021108: Phase II Study of Short Course FOLFOX Chemotherapy With Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol ) |
|
|
| Active, not recruiting | 2 | 80 | US | Nivolumab 240 MG | Weill Medical College of Cornell University, Bristol-Myers Squibb | Gastroesophageal Adenocarcinoma | 04/25 | 04/26 | | |
NCT04412629: Cabozantinib in High Grade Neuroendocrine Neoplasms |
|
|
| Recruiting | 2 | 32 | US | Cabozantinib, Cabometyx, Blood for plasma biomarkers, Tissue biopsy | Washington University School of Medicine, Exelixis | High Grade Neuroendocrine Neoplasms | 07/25 | 03/26 | | |
NCT04162665: Pre-operative Adaptive Short Court Radiation Therapy in Gastric Cancer |
|
|
| Terminated | 2 | 4 | US | Adaptive short course radiation therapy, Standard of care chemotherapy regimen | Washington University School of Medicine, Viewray Inc. | Gastric Adenocarcinoma | 12/23 | 11/24 | | |
NCT03516708: Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer |
|
|
| Recruiting | 1/2 | 49 | US | Epacadostat, INCB024360, Short-course radiation therapy, SCRT, CAPOX chemotherapy, FOLFOX chemotherapy | Washington University School of Medicine, Incyte Corporation, National Cancer Institute (NCI) | Rectal Cancer | 07/27 | 08/30 | | |
|
FIH, NCT04294576: Safety Study of BJ-001, an IL-15 Fusion Protein, for Locally Advanced/Metastatic Solid Tumors |
|
|
| Active, not recruiting | 1b | 92 | US | BJ-001, Pembrolizumab, Keytruda | BJ Bioscience, Inc., PPD, Merck Sharp & Dohme LLC | Locally Advanced/Metastatic Solid Tumors | 04/24 | 10/24 | | |
NCT04306224: A Study of IMC-002 in Subjects With Metastatic or Locally Advanced Solid Tumors and Relapsed or Refractory Lymphomas |
|
|
| Completed | 1 | 12 | US, RoW | IMC-002 | ImmuneOncia Therapeutics Inc. | Solid Tumor, Lymphoma | 10/22 | 10/22 | | |
| Recruiting | 1 | 162 | US | XMT-2056 | Mersana Therapeutics | HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2-positive Non-Small Cell Lung Cancer, HER2-positive Colorectal Cancer, HER2-positive Tumors, HER2 Low Breast Cancer | 04/27 | 04/27 | | |
| Weiss, Mia |
SARC041, NCT04967521: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma |
|
|
| Active, not recruiting | 3 | 108 | US | Abemaciclib, LY2835219, Placebo | Sarcoma Alliance for Research through Collaboration, Eli Lilly and Company | Advanced Dedifferentiated Liposarcoma | 12/25 | 12/26 | | |
NCT04551430: Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma |
|
|
| Active, not recruiting | 2 | 105 | US | Cabozantinib, Nivolumab, Opdivo, Ipilimumab, Yervoy | Washington University School of Medicine, Exelixis, Bristol-Myers Squibb | Metastatic Soft-tissue Sarcoma | 06/24 | 06/30 | | |
| Recruiting | 2 | 114 | US | Doxorubicin, L19TNF plus doxorubicin | Philogen S.p.A. | Leiomyosarcoma | 12/24 | 12/25 | | |
| Active, not recruiting | 1/2 | 300 | US, RoW | CAB-AXL-ADC, PD-1 inhibitor | BioAtla, Inc. | Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma | 01/25 | 01/25 | | |
NCT05813327: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma |
|
|
| Recruiting | 1/2 | 35 | US | ADI PEG20, PEGylated arginine deiminase, Ifosfamide, ifex, Radiotherapy, Mesna, sodium 2-mercaptoethane sulfonate | Washington University School of Medicine, Polaris Group | Soft Tissue Sarcoma, Sts, Sarcoma,Soft Tissue | 01/26 | 01/28 | | |
NCT05616624: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers |
|
|
| Recruiting | 1/2 | 114 | US | ADI-PEG 20, PEGylated arginine deiminase, Gemcitabine, Gemzar, Docetaxel, Taxotere | Washington University School of Medicine, Polaris Group | Non Small Cell Lung Cancer, Non-small Cell Lung Cancer, Small-cell Lung Cancer, Small Cell Lung Carcinoma | 12/27 | 12/32 | | |
NCT05100628: A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma |
|
|
| Terminated | 1 | 9 | US | NOX66, Doxorubicin | Noxopharm Limited | Metastatic Soft-tissue Sarcoma | 05/23 | 05/23 | | |
NCT04237649: KAZ954 Alone and With PDR001, NZV930 and NIR178 in Advanced Solid Tumors |
|
|
| Terminated | 1 | 77 | Europe, Canada, Japan, US, RoW | KAZ954, PDR001, NIR178, NZV930 | Novartis Pharmaceuticals | Solid Tumors | 09/23 | 09/23 | | |
