Zhang, Yizhuo |
NCT06208917: Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children |
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| Recruiting | 3 | 376 | RoW | Ondansetron (Oral soluble film OR injections) ,Dexamethasone, Ondansetron,Dexamethasone | Yizhuo Zhang | Pediatric Solid Tumor, Unspecified, Protocol Specific | 07/26 | 01/27 | | |
NCT06434467: The Efficacy and Safety of Nelarabine Injection in Patients With T-lymphoblastic Leukemia and T-lymphoblastic Lymphoma |
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| Not yet recruiting | 3 | 83 | RoW | Nelarabine injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | T-lymphoblastic Leukemia, T-lymphoblastic Lymphoma | 12/25 | 05/26 | | |
NCT04547829: Safety and Efficacy of PEG-rhG-CSF in Preventing Neutropenia in Children With Tumor After Chemotherapy |
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| Recruiting | 2 | 108 | RoW | pegylated recombinant human granulocyte-colony stimulating factor | Sun Yat-sen University | Pediatric Cancer | 10/22 | 05/23 | | |
NCT04508400: Fosaprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric Patients |
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| Completed | 2 | 108 | RoW | Fosaprepitant,ondansetron, dexamethasone, ondansetron, dexamethasone, placebo ondansetron with dexamethasone | Sun Yat-sen University | Pediatric Cancer | 06/23 | 06/23 | | |
NCT04581265: Nab-PTX, Ifosfamide and Cisplatin in the Treatment of Pediatric Extracranial Germ Cell Tumor. |
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| Not yet recruiting | 2 | 43 | NA | albumin-bound paclitaxel (nab-PTX), ifosfamide and cisplatin | Sun Yat-sen University | Extracranial Germ Cell Tumor, Pediatric | 11/23 | 05/24 | | |
NCT06013618: Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma |
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| Recruiting | 2 | 30 | RoW | Naxitamab monotherapy, hu3F8, GM-CSF, Recombinant Human Granulocyte/Macrophage Colony-stimulating Factor, Irinotecan, DNA topoisomerase I inhibitor, Temozolomide, Temozolomide for Injection, Naxitamab in combination therapy, GM-CSF with combination regimen, Sintilimab, PD-1 antibody | Sun Yat-sen University, Hainan General Hospital | Neuroblastoma | 12/24 | 12/24 | | |
NCT05027386: Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma |
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| Recruiting | 2 | 62 | RoW | Apatinib, Irinotecan, Temozolomide, Irinotecan, temozolomide | Sun Yat-sen University | Neuroblastoma | 12/25 | 12/25 | | |
NCT06456892: Effectiveness of Pucotenlimab Combined With Standard Chemotherapy Regimen |
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| Recruiting | 1/2 | 82 | RoW | Pucotenlimab | Sun Yat-sen University | Rhabdomyosarcoma, Pediatric Cancer | 06/26 | 12/26 | | |
NCT04400851: Sintilimab in the Treatment of Advanced and Refractory Pediatric Malignant Tumors |
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| Recruiting | 1 | 18 | RoW | Sintilimab | Sun Yat-sen University, Innovent Biologics (Suzhou) Co. Ltd. | Pediatric Cancer | 10/21 | 12/21 | | |
NCT06760117: UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors |
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| Recruiting | 1 | 39 | RoW | Irinotecan (CPT-11), Temozolomide (TMZ), Vincristine | Sun Yat-sen University | Pediatric Solid Tumor | 06/25 | 12/25 | | |
NCT04659733: Phase I Clinical Trial of Anlotinib in Progressive, Recurrent, and Refractory Sarcoma in Children |
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| Not yet recruiting | 1 | 36 | NA | Anlotinib hydrochloride | Yizhuo Zhang | Sarcoma | 12/22 | 12/22 | | |
| Recruiting | 1 | 30 | RoW | Tucidinostat and etoposide | Yizhuo Zhang | Neuroblastoma in Children | 06/24 | 12/24 | | |
NCT06631391: Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma. |
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| Not yet recruiting | 1 | 30 | RoW | umbilical cord blood NK cells | Sun Yat-sen University | Neuroblastoma | 11/26 | 11/29 | | |
NCT05701306: APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors |
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| Recruiting | 1 | 100 | RoW | APG-115, APG-2575 | Ascentage Pharma Group Inc., Suzhou Yasheng Pharmaceutical Co., Ltd. | Neuroblastoma, Solid Tumor | 06/26 | 12/27 | | |
NCT05778955: Study on Dynamic CtDNA Analysis in Pediatric Soft Tissue Sarcoma |
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| Recruiting | N/A | 40 | RoW | detection and monitoring of cirulating tumor DNA | Sun Yat-sen University, Nanjing Geneseeq Technology Inc. | Pediatric Soft Tissue Sarcoma | 12/23 | 12/23 | | |
NCT04957901: The Value of Monitoring Circulating Cell DNA (ctDNA) in Pediatric Mature B Cell Non-Hodgkins Lymphoma (NHL). |
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| Recruiting | N/A | 60 | RoW | modified BFM-95 protocol | Sun Yat-sen University | Non-hodgkin Lymphoma | 06/26 | 06/26 | | |