| Villella, Jeannine A |
PROTA, NCT05271318: Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab and Pegylated Liposomal Doxorubicin as Treatment for Ovarian Cancer. |
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| Recruiting | 1 | 29 | Europe, US | TILT-123, Ad5/3-E2F-d24-hTNFa-IRES-hIL2 (TILT-123), pembrolizumab, KEYTRUDA®, MK-3475, pegylated liposomal doxorubicin, PLD | TILT Biotherapeutics Ltd., Merck Sharp & Dohme LLC | Platinum-refractory Ovarian Carcinoma, Platinum-resistant Ovarian Cancer, Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Platinum-Refractory Fallopian Tube Carcinoma, Platinum-Refractory Primary Peritoneal Carcinoma, Platinum-Sensitive Ovarian Cancer in Which the Participant Has Allergy or Severe Intolerance to Carboplatin and/or Cisplatin, Platinum-Sensitive Fallopian Tube Carcinoma in Which the Participant Has Allergy or Severe Intolerance to Carboplatin and/or Cisplatin, Platinum-Sensitive Primary Peritoneal Carcinoma in Which the Participant Has Allergy or Severe Intolerance to Carboplatin and/or Cisplatin | 01/25 | 01/27 | | |
| Maesaka, John K |
NCT05298384: Pathophysiologic Study to Understand and Possibly Treat Nocturia |
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| Withdrawn | N/A | 20 | US | Compression stockings | NYU Langone Health | Nocturia | 10/24 | 11/24 | | |
| Schwartz, Richard |
| Completed | 2 | 96 | US, RoW | Varespladib Methyl, LY333013, Placebo, Standard of care (SOC) | Ophirex, Inc., Premier Research Group plc | Snakebites, Envenoming, Envenoming, Snake, Envenomation, Snake | 06/23 | 06/23 | | |
| Recruiting | N/A | 1150 | US, RoW | Portico transcatheter aortic valve, Commercially available transcatheter aortic valve | Abbott Medical Devices | Aortic Valve Stenosis | 10/19 | 07/25 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
COMPLETE TAVR, NCT04634240: Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement |
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| Recruiting | N/A | 4000 | Canada, US | Percutaneous Coronary Intervention (PCI) | University of British Columbia | Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis | 04/26 | 04/26 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Recruiting | N/A | 1000 | Canada, US | | Medstar Health Research Institute | Mitral Valve Disease | 02/27 | 02/27 | | |
| Chinitz, Larry |
RIDGE-1, NCT06228924: Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC |
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| Recruiting | 1 | 15 | US | TN-401 | Tenaya Therapeutics, Johns Hopkins University, Mayo Clinic | Arrhythmogenic Right Ventricular Cardiomyopathy | 05/26 | 10/29 | | |
| Recruiting | N/A | 30 | US | Cardiac ablation via catheter | EPD Solutions, A Philips Company | Atrial Fibrillation and Flutter | 06/22 | 06/22 | | |
RIDGE, NCT06311708: Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) |
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| Recruiting | N/A | 200 | Europe, US | | Tenaya Therapeutics, University of California, San Francisco, Brigham and Women's Hospital, New York University, University of Colorado, Denver, Johns Hopkins University, The Cleveland Clinic, Mayo Clinic, Medical University of South Carolina, Hopital Louis Pradel, Istituti Clinici Scientifici Maugeri SpA, The Queen Elizabeth Hospital, St George's University Hospitals NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Barts & The London NHS Trust, Skane University Hospital, Centro Cardiologico Monzino, Hôpital Haut-Lévêque, Nantes University Hospital, Pitié-Salpêtrière Hospital, Wuerzburg University Hospital, University Hospital Muenster | Arrhythmogenic Right Ventricular Cardiomyopathy | 03/30 | 07/30 | | |
PSOT, NCT03481413: Patient Specific Optimized Therapy Post-Market Clinical Follow-up Study |
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| Terminated | N/A | 566 | Europe, US, RoW | Ablation | EPD Solutions, A Philips Company | Arrythmia | 03/23 | 03/23 | | |
| Recruiting | N/A | 475 | Europe, Canada, US | Amulet™ 2 Left Atrial Appendage (LAA) Occluder | Abbott Medical Devices | Atrial Fibrillation (AF), Stoke | 07/26 | 07/28 | | |
NCT06676072: A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects with PAF: |
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| Recruiting | N/A | 188 | Europe, US | PFA Ablation catheter | Abbott Medical Devices | Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation | 04/26 | 04/26 | | |
| Recruiting | N/A | 200 | US | ViewFlex X ICE System | Abbott Medical Devices | Cardiac Arrhythmias | 12/25 | 12/25 | | |
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation |
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| Active, not recruiting | N/A | 669 | Europe, Canada, US | Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System | Boston Scientific Corporation | Persistent Atrial Fibrillation | 03/25 | 03/25 | | |
| Active, not recruiting | N/A | 610 | US | Left atrial appendage occlusion (LAAO) | Abbott Medical Devices | Atrial Fibrillation, Stroke, Bleeding | 06/27 | 06/27 | | |
NCT04502316: Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry) |
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| Recruiting | N/A | 5000 | US | Barostim™ System | CVRx, Inc. | Heart Failure | 06/28 | 06/28 | | |
| Recruiting | N/A | 4000 | Europe, Canada, US | WATCHMAN device | Hamilton Health Sciences Corporation, McMaster University, Population Health Research Institute, Boston Scientific Corporation | Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism | 09/29 | 12/29 | | |
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry |
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| Recruiting | N/A | 1000 | Europe, Canada, US, RoW | Defibrillation using EV-ICD | Medtronic | Ventricular Arrhythmia, Tachycardia | 05/30 | 10/37 | | |
| Hanna, Nazeeh |
NCT02935946: Cold Liquids Fed to Preterm Infants: Efficacy and Safety After 10 Minutes of Exposure |
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| Completed | N/A | 4043 | US | Cold Liquid Barium | NYU Langone Health, Adelphi University | Deglutition Disorders, Respiratory Aspiration | 03/24 | 03/24 | | |
| Completed | N/A | 22 | US | Standard room temperature (RTS) feeding of milk/formula, Cold temperature (CS, at 4-9°C) of milk/formula | NYU Langone Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Dysphagia of Newborn | 03/24 | 03/24 | | |
| Patel, Dipti |
| Recruiting | 2 | 72 | Europe, US | remibrutinib, (LOU064), placebo | Novartis Pharmaceuticals, Novartis Pharma AG | Allergy, Peanut | 03/25 | 03/25 | | |
| Germano, Joseph J |
REACT-AF, NCT05836987: The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation |
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| Recruiting | 3 | 5350 | US | AFSW Guided DOAC, Apple Watch, Continuous DOAC therapy, Oral Anticoagulation therapy | Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI) | Atrial Fibrillation | 07/29 | 07/29 | | |
| Active, not recruiting | N/A | 610 | US | Left atrial appendage occlusion (LAAO) | Abbott Medical Devices | Atrial Fibrillation, Stroke, Bleeding | 06/27 | 06/27 | | |
| Completed | N/A | 973 | US | Non-Interventional | Medtronic Cardiac Rhythm and Heart Failure | Atrial Fibrillation | 01/24 | 01/24 | | |
| DeLeon, Joshua |
| No trials found |
