Huang, Jing |
NCT04486651: HX008 Plus Irinotecan Versus Placebo Plus Irinotecan as Second-line Treatment in Advanced Gastric Cancer |
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| Recruiting | 3 | 560 | RoW | Irinotecan Hydrochloride Injection, HX008, Placebo | Taizhou Hanzhong biomedical co. LTD | Stomach Cancer | 08/23 | 08/23 | | |
NCT06194734: A Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer |
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| Recruiting | 3 | 490 | RoW | KC1036, Irinotecan, Docetaxel, S-1, Tegafur-gimeracil-oteracil potassium | Beijing Konruns Pharmaceutical Co., Ltd. | Esophageal Squamous Cell Carcinoma | 12/26 | 12/27 | | |
NCT05838573: Metformin Treatment on Cognitive Impairment of Schizophrenia |
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| Recruiting | 3 | 120 | RoW | Metformin treatment, Placebo treatment, Baseline assessments, Volunteer assessments | Central South University, NINGBO KANGNING HOSPITAL, Shandong Mental Health Center, The Second People's Hospital of Dali Bai Autonomous Prefecture | Schizophrenia | 07/25 | 12/25 | | |
NCT05652894: A Study of HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer |
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| Not yet recruiting | 3 | 190 | RoW | HX008, Investigator's Choice Chemotherapy | Taizhou Hanzhong biomedical co. LTD | Metastatic Colorectal Cancer | 01/26 | 10/28 | | |
| Not yet recruiting | 2 | 120 | RoW | bear bile pill, placebo | Shanghai Mental Health Center | Major Depressive Disorder | 03/22 | 03/22 | | |
NCT04886271: Recombinant Humanized Anti-CD47 / PD-1 Bifunctional Antibody HX009 Injection in the Treatment of Advanced Solid Tumors |
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| Active, not recruiting | 2 | 210 | RoW | HX009 | Waterstone Hanxbio Pty Ltd | Advanced Solid Tumor | 12/22 | 02/23 | | |
NCT05145907: Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid Tumors |
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| Active, not recruiting | 2 | 133 | RoW | TJ107 +Pembrolizumab | TJ Biopharma Co., Ltd. | Triple-negative Breast Cancer, Head and Neck Squamous Cell Carcinoma | 06/24 | 12/24 | | |
NOVA-II, NCT04088318: A Study to Investigate OQL011 on VEGFR Inhibitor-Associated Hand-Foot Skin Reaction in Cancer Patients |
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| Active, not recruiting | 2 | 170 | US, RoW | OQL011, Vehicle Ointment | OnQuality Pharmaceuticals (USA) LLC | Hand-Foot Skin Reaction (HFSR) | 02/24 | 06/24 | | |
NCT06154538: Cadonilimab + FOLFOX Versus FOLFOX in the Neoadjuvant Treatment of pMMR/MSS Locally Advanced Colorectal Cancer |
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| Recruiting | 2 | 170 | RoW | Cadonilimab, 1, FOLFOX regimen | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Locally Advanced Colorectal Carcinoma | 11/26 | 11/28 | | |
| Not yet recruiting | 2 | 80 | NA | AK104, Cadonilimab, Cisplatin, DDP, Paclitaxel, PTX | Chinese Academy of Medical Sciences, Akeso Pharmaceuticals, Inc. | Unresectable Esophageal Squamous Cell Carcinoma, Locally Advanced Esophageal Squamous Cell Carcinoma, Metastatic Esophageal Squamous Cell Carcinoma | 04/24 | 10/24 | | |
NCT05648006: First-line Maintenance of OH2 Injection for Advanced Colorectal Cancer |
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| Terminated | 2 | 7 | RoW | OH2, Capecitabine, Bevacizumab | Binhui Biopharmaceutical Co., Ltd. | Advanced Colorectal Carcinoma | 04/24 | 04/24 | | |
NCT05221658: A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC |
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| Recruiting | 2 | 60 | RoW | HLX07+HLX10+ Cisplatin+5-FU, HLX07 | Shanghai Henlius Biotech | ESCC or Esophageal Adenosquamous Carcinoma | 06/24 | 08/25 | | |
NCT04755543: A Study of LP002 for the Treatment of Patients With Malignant Digestive System Neoplasms |
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| Recruiting | 1 | 94 | RoW | LP002, Cisplatin, Fluorouracil, OH2 oncolytic virus | Taizhou HoudeAoke Biomedical Co., Ltd. | Digestive System Neoplasms | 06/21 | 06/22 | | |
| Recruiting | 1 | 228 | RoW | Recombinant Humanized Monoclonal Antibody MIL93 | Beijing Mabworks Biotech Co., Ltd. | Advanced Malignancies | 08/25 | 08/25 | | |
NCT06205082: A Phase I Clinical Trial to Evaluate LIT-00814 Tablets in Patients With Advanced Solid Tumor |
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| Enrolling by invitation | 1 | 81 | RoW | LIT-00814 | LittDD Medicines Ltd | Advanced Solid Tumor | 10/25 | 06/26 | | |
NCT06143007: A Phase 1 Study of BB3008 in Participants With Advanced Solid Tumors |
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| Recruiting | 1 | 42 | RoW | BB3008 tablet, BB3008 | BrodenBio Co., Ltd. | Advanced Solid Tumor | 11/25 | 04/26 | | |
NCT05783063: iTBS for Increased Appetite Induced by Antipsychotics |
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| Recruiting | N/A | 60 | RoW | Active iTBS, Sham iTBS | Central South University | Schizophrenia | 08/24 | 12/24 | | |
NCT05795829: Ultrasound Ablation for Essential Hypertension(FIM) |
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| Recruiting | N/A | 10 | RoW | disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument | Lepu Medical Technology (Beijing) Co., Ltd. | Uncontrolled Essential Hypertension | 12/23 | 02/24 | | |
NCT06210100: aiTBS for NSSI and Suicide in Adolescent Depression |
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| Recruiting | N/A | 60 | RoW | Active iTBS, Sham iTBS | Central South University | Non Suicidal Self Injury, Suicidal Ideation, Suicide and Self-harm | 12/24 | 02/25 | | |
NCT05384405: aiTBS for Relieving NSSI in Depressive Patients |
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| Recruiting | N/A | 60 | RoW | Active iTBS, Sham iTBS | Central South University | Major Depressive Disorder, Bipolar Depression | 02/25 | 02/25 | | |
NCT06116357: The Safety and Efficacy of Carotid Body Modulation Therapy in Hypertensive Patients by External Ultrasonic Micro-bubble |
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| Not yet recruiting | N/A | 200 | RoW | External Ultrasonic Micro-bubble | Jing Huang, The Second Affiliated Hospital of Chongqing Medical University | Primary Hypertension | 09/26 | 12/26 | | |
NCT05307848: Reproductive Function in Women With Bipolar Disorder |
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| Recruiting | N/A | 200 | RoW | No intervention | Central South University | Bipolar Disorder | 02/23 | 02/23 | | |
Wu, Renrong |
NCT05838573: Metformin Treatment on Cognitive Impairment of Schizophrenia |
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| Recruiting | 3 | 120 | RoW | Metformin treatment, Placebo treatment, Baseline assessments, Volunteer assessments | Central South University, NINGBO KANGNING HOSPITAL, Shandong Mental Health Center, The Second People's Hospital of Dali Bai Autonomous Prefecture | Schizophrenia | 07/25 | 12/25 | | |
NCT03932136: Decreasing Risk of Psychosis by Sulforaphane (DROPS Trial) |
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| Recruiting | 3 | 300 | RoW | Sulforaphane, ZHIYINGUOSU, Placebo | Shanghai Jiao Tong University School of Medicine, Shanghai Xuhui District Mental Health Center, Shanghai Pudong Nanhui Mental Health Center, Suzhou Psychiatric Hospital, Second Xiangya Hospital of Central South University, Guangzhou Psychiatric Hospital, Shenzhen Fushan Biotech Co., Ltd., Tianjin Anding Hospital, The First Affiliated Hospital of Zhengzhou University, Shenzhen Kangning Hospital | Clinical High Risk Syndrome of Psychosis | 12/25 | 12/26 | | |
NCT04246905: A 12-weeks Study to Evaluate Sulforaphane in the Treatment of Depression |
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| Recruiting | 2 | 90 | RoW | sulforaphane, placedo, selective 5 - HT reuptake inhibitors (SSRI) | Central South University | Depressive Disorder | 12/21 | 12/21 | | |
NCT04521868: A 6-month Study to Evaluate Sulforaphane Effects in Schizophrenia Patients |
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| Completed | 2 | 125 | RoW | Sulforaphane, Nutramax, placebo | Central South University | Schizophrenia | 08/22 | 08/22 | | |
NCT05084365: A 6-month Study to Evaluate Sulforaphane Effects in PD Patients |
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| Recruiting | 2 | 100 | RoW | Sulforaphane, Placebo | Central South University | Parkinson Disease | 11/23 | 12/23 | | |
NCT03379597: A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder |
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| Completed | N/A | 136 | RoW | Bifico (Live combined bifidobacterium,Lactobacillus and Enterococcus capsules, Oral), Dietary fiber | Central South University | Schizophrenia, Bipolar Disorder | 05/21 | 06/21 | | |
NCT04714970: rTMS on Appetite and Cognitive Function in Schizophrenia |
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| Active, not recruiting | N/A | 10 | RoW | iTBS, Shame stimulation | Central South University, Shanghai Mental Health Center | Schizophrenia | 11/22 | 12/22 | | |
NCT05783063: iTBS for Increased Appetite Induced by Antipsychotics |
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| Recruiting | N/A | 60 | RoW | Active iTBS, Sham iTBS | Central South University | Schizophrenia | 08/24 | 12/24 | | |
NCT03271866: Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic Syndrome |
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| Recruiting | N/A | 80 | RoW | metformin | Central South University | Schizophrenia | 12/23 | 12/23 | | |
NCT05384405: aiTBS for Relieving NSSI in Depressive Patients |
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| Recruiting | N/A | 60 | RoW | Active iTBS, Sham iTBS | Central South University | Major Depressive Disorder, Bipolar Depression | 02/25 | 02/25 | | |
NCT06428968: Investigating the Insulin Resistance in Individuals With Type 2 Diabetes |
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| Not yet recruiting | N/A | 30 | RoW | 160 units nasal insulin spray | Central South University | Type 2 Diabetes | 12/24 | 06/25 | | |
NCT05448430: iTBS Can Increase Frontal Dopamine Release in PET Dopamine Imaging. |
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| Not yet recruiting | N/A | 50 | RoW | Theta burst stimulation | Central South University | Schizophrenia | 07/24 | 07/24 | | |
NCT05137158: iTBS on Negative Symptoms and Cognitive Function in Schizophrenia |
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| Completed | N/A | 60 | RoW | Intermittent theta burst stimulation, Sham stimulation | Central South University | Schizophrenia | 06/24 | 06/24 | | |
NCT05396989: A Correlation Study of Cognitive Function in Patients With Depression |
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| Not yet recruiting | N/A | 200 | RoW | No intervention | Central South University | Depression | 05/28 | 05/28 | | |
NCT06123897: Establishing a Clinical Database and Biobank for Schizophrenia:A Cohort Study |
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| Recruiting | N/A | 2000 | RoW | Regular follow-up assessments without intervention., Cross-sectional assessment | Central South University | Schizophrenia | 07/28 | 12/28 | | |