| Marsh, Robert de W |
| Active, not recruiting | 3 | 615 | Europe, Canada, US, RoW | Oregovomab, MAb-B43.13, Paclitaxel, Taxol, Carboplatin, Paraplatin, Placebo | CanariaBio Inc., Gynecologic Oncology Group, Iqvia Pty Ltd | Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma, Fallopian Tube Neoplasms, Fallopian Tube Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Peritoneal Cancer, Peritoneal Carcinoma, Peritoneal Neoplasms | 09/25 | 08/27 | | |
RAMP 301, NCT06072781: A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer |
|
|
| Recruiting | 3 | 270 | Europe, Canada, US, RoW | avutometinib, avutometinib (VS-6766), Defactinib, defactinib (VS-6063), Pegylated liposomal doxorubicin, Caelyx, Doxil, Lipodox, Paclitaxel, Nov-Onxol, Onxol, Navaplus, Taxol, Letrozole, Femara, Anastrozole, Arimidex | Verastem, Inc., GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Australia New Zealand Gynaecological Oncology Group | Low Grade Serous Ovarian Cancer | 10/28 | 02/31 | | |
| Recruiting | 2 | 76 | Canada, US, RoW | ZN-c3, azenosertib, KP-2638 | K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc | Uterine Serous Carcinoma | 11/24 | 05/25 | | |
PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers |
|
|
| Completed | 2 | 79 | Europe, Canada, US, RoW | Mirvetuximab soravtansine, MIRV, IMGN853 | AbbVie | Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer | 01/24 | 12/24 | | |
|
|
|
|
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Rodgers, Richard B |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Emery, Sanford E |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Daffner, Scott |
NCT05405374: OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study |
|
|
| Recruiting | N/A | 101 | US | OSTEOAMP, Infuse | Bioventus LLC | Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease | 10/24 | 10/25 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Eicher, Jennifer |
| Withdrawn | 2 | 90 | US | Bacteriophage, Placebo | Adaptive Phage Therapeutics, Inc. | Prosthetic Joint Infection | 07/25 | 07/27 | | |
MAGIC, NCT05361941: Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities |
|
|
| Recruiting | N/A | 204 | US | EP Granules with Tobramycin, empty voids | Elute, Inc. | Periprosthetic Joint Infections | 12/25 | 12/25 | | |
NCT05405374: OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study |
|
|
| Recruiting | N/A | 101 | US | OSTEOAMP, Infuse | Bioventus LLC | Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease | 10/24 | 10/25 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
NCT05339594: REINVENT Registry (Registry of the Nerve Gap Repair From Integra) |
|
|
| Terminated | N/A | 17 | US | NeuraGen, NeuraGen 3D | Integra LifeSciences Corporation | Peripheral Nerve Injuries | 06/24 | 06/24 | | |
| Warren, Debbi |
NCT06741527: Integrity Implant System Post Market Clinical Follow-Up Study |
|
|
| Not yet recruiting | 4 | 150 | US | Integrity Implant System | Anika Therapeutics, Inc. | Rotator Cuff Tears of the Shoulder | 06/27 | 10/27 | | |
NCT04012996: 2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C |
|
|
| Recruiting | N/A | 390 | US | prodisc C SK and/or Vivo, Mobi-C Cervical Disc | Centinel Spine | Symptomatic Cervical Disc Disease | 01/23 | 02/28 | | |
| Recruiting | N/A | 200 | US | Lumbar Interbody Fusion | 3Spine, MCRA | Lumbar Spine Degeneration | 05/24 | 08/26 | | |
| Recruiting | N/A | 300 | US | OssDsign® Catalyst | OssDsign | Degenerative Disc Disease, Spinal Stenosis | 03/27 | 04/27 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Recruiting | N/A | 20 | US | Axoguard HA+ Nerve Protector™ | Axogen Corporation | Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome | 12/26 | 12/26 | | |
| Terminated | N/A | 8 | US | Surgical Management of Neuroma | Axogen Corporation | Chronic Neuropathic Pain | 01/24 | 01/24 | | |
NCT06040827: A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension |
|
|
| Recruiting | N/A | 626 | US | Total Knee Arthroplasty | Canary Medical | Knee Osteoarthritis | 06/28 | 12/28 | | |
NCT05719935: The KinematX Midcarpal Total Wrist Arthroplasty Registry |
|
|
| Recruiting | N/A | 50 | US | KinematX total wrist arthroplasty system | Extremity Medical | Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS), Kienbock's Disease of Adults, Radial Malunion, Ulnar Translocation, Post Traumatic Arthritis, Inflammatory Arthritis, Osteoarthritis, Scaphoid Non-union Advanced Collapse (SNAC) | 12/35 | 12/35 | | |
| Vinayek, Sheetal |
NCT04012996: 2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C |
|
|
| Recruiting | N/A | 390 | US | prodisc C SK and/or Vivo, Mobi-C Cervical Disc | Centinel Spine | Symptomatic Cervical Disc Disease | 01/23 | 02/28 | | |
NCT03118505: A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions |
|
|
| Active, not recruiting | N/A | 100 | US | Infuse Bone Graft, Medtronic DBM | Medtronic Spinal and Biologics | Multi-Level Degenerative Lumbosacral Spinal Conditions | 04/26 | 12/26 | | |
NCT04520776: A Clinical Trial Comparing the BAGUERA C to the Marketed Mobi-C® for the Treatment of Single Level Cervical Disc Disease |
|
|
| Active, not recruiting | N/A | 284 | US | BAGUERA®C Cervical Disc Prosthesis, Mobi-C® Cervical Disc | Spineart USA | Cervical Disc Disease | 02/26 | 02/26 | | |
NCT04564885: A Clinical Trial Comparing the BAGUERA C to the Marketed Mobi-C® for the Treatment of Cervical Disc Disease at 2 Contiguous Levels |
|
|
| Active, not recruiting | N/A | 300 | US | BAGUERA®C Cervical Disc Prosthesis, Mobi-C Cervical Disc | Spineart USA | Cervical Disc Disease | 04/25 | 04/30 | | |
NCT04469231: The Synergy Disc To Anterior Cervical Discectomy and Fusion |
|
|
| Active, not recruiting | N/A | 175 | US | Anterior Cervical Discectomy & Fusion, ACDF | Synergy Spine Solutions, MCRA | Cervical Degenerative Disc Disease | 01/25 | 01/26 | | |
NCT05405374: OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study |
|
|
| Recruiting | N/A | 101 | US | OSTEOAMP, Infuse | Bioventus LLC | Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease | 10/24 | 10/25 | | |
STAND, NCT04835428: - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients with Vertebral Compression Fractures |
|
|
| Recruiting | N/A | 408 | US | Treatment Group: AGN1 LOEP SV Kit, Control Group: PMMA bone cement | AgNovos Healthcare, LLC | Vertebral Compression Fracture, Compression Fracture, Vertebral Compression | 12/25 | 12/27 | | |
| Recruiting | N/A | 5000 | Europe, US | RTI Spine products | Xtant Medical, RTI Surgical | Sacroiliac; Fusion, Sacroiliac, Joint Diseases, Musculoskeletal Diseases, Spinal Disease, Spinal Stenosis, Spinal Instability, Fusion of Joint, Fusion of Spine, Spinal Fusion, Spine | 03/25 | 06/25 | | |
NCT05740176: The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery |
|
|
| Active, not recruiting | N/A | 200 | US | Anterior Cervical Discectomy and Fusion, ACDF | Synergy Spine Solutions, MCRA | Cervical Degenerative Disc Disease | 09/26 | 12/26 | | |
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation |
|
|
| Active, not recruiting | N/A | 203 | US | ReActiv8 | Mainstay Medical | Chronic Low-back Pain | 09/24 | 01/26 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Recruiting | N/A | 1000 | US | Follow-up schedule: pre-operative baseline up to 24-months post-procedure | Medtronic Spinal and Biologics, Medtronic Bakken Research Center | Spinal Deformity, Spinal Degenerative Disorder, Spinal Fusion Failure, Spinal Trauma, Spinal Tumor Case | 05/31 | 05/31 | | |
| Smucker, Joseph |
NCT03118505: A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions |
|
|
| Active, not recruiting | N/A | 100 | US | Infuse Bone Graft, Medtronic DBM | Medtronic Spinal and Biologics | Multi-Level Degenerative Lumbosacral Spinal Conditions | 04/26 | 12/26 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Recruiting | N/A | 1000 | US | Follow-up schedule: pre-operative baseline up to 24-months post-procedure | Medtronic Spinal and Biologics, Medtronic Bakken Research Center | Spinal Deformity, Spinal Degenerative Disorder, Spinal Fusion Failure, Spinal Trauma, Spinal Tumor Case | 05/31 | 05/31 | | |
| France, John |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Harman, Paige |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Matheus, Virgilio |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Cui, Shari |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Sedney, Cara |
NCT05405374: OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study |
|
|
| Recruiting | N/A | 101 | US | OSTEOAMP, Infuse | Bioventus LLC | Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease | 10/24 | 10/25 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Bhatia, Sanjay |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Potts, Eric |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| DePowell, John |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
