| Jakicic, John |
| Terminated | N/A | 8 | US | Dietary Intervention, Physical Activity Intervention | University of Pittsburgh, National Cancer Institute (NCI) | Bladder Cancer, Telomere Shortening, Colorectal Adenoma | 12/20 | 10/24 | | |
CogEx, NCT03696082: A Precision Rehabilitation Approach to Counteract Age-Related Cognitive Declines |
|
|
| Terminated | N/A | 78 | US | Aerobic Activity, Resistance Training, Yoga, Health Education | University of Pittsburgh | Cognition Disorders, Brain Pathology, Physical Disability, Physical Activity, Aging | 01/22 | 12/22 | | |
| Recruiting | N/A | 660 | US | Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education, Usual Care | Duke University, National Heart, Lung, and Blood Institute (NHLBI) | Long COVID, Long Covid19, Long Covid-19 | 10/25 | 01/26 | | |
NCT06636773: Comparision of Aerobic Exercise to Aerobic Plus Yoga Exercise for Weight Loss in Adults With Overweight or Obesity. |
|
|
| Recruiting | N/A | 290 | US | Diet, Aerobic Exercise, Behavioral Sessions, Aerobic + Yoga Exercise | University of Kansas Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Obesity and Overweight | 11/28 | 11/28 | | |
HEAL, NCT06640179: Evaluation of the Feasibility and Plausible Effectiveness of a Lifestyle Intervention on Change in Weight, Effects on Cardiometabolic Biomarkers, and Kidney Function in Kidney Transplant Recipients |
|
|
| Not yet recruiting | N/A | 60 | US | Standard medical care, Monitoring Contacts, Behavioral Sessions, Diet, Physical Activity | University of Kansas Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Kidney Transplant, Overweight or Obese Adults, Glucose Control | 10/26 | 03/27 | | |
| Recruiting | N/A | 40 | US | Standard Medical Care (SMC), Monitoring Contacts, Aerobic Training, Resistance Training, Nutrition Education | University of Kansas Medical Center, National Institute of General Medical Sciences (NIGMS) | Obesity and Overweight | 09/25 | 12/25 | | |
| Saba, Samir |
AVANT GUARD, NCT06096337: Pulsed Field Ablation (PFA) Vs Anti-Arrhythmic Drug (AAD) Therapy As a First Line Treatment for Persistent Atrial Fibrillation |
|
|
| Recruiting | N/A | 520 | Europe, Canada, US, RoW | FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone | Boston Scientific Corporation | Persistent Atrial Fibrillation | 12/25 | 12/27 | | |
| Recruiting | N/A | 200 | US | Standard of Care, Control, ICM Implantation, ICM | Samir Saba, Abbott | Acute Myocardial Infarction | 10/25 | 10/25 | | |
NCT06684457: Patient Perceived Empathy of an AI Chatbot for Atrial Fibrillation Education |
|
|
| Recruiting | N/A | 40 | US | Atrial Fibrillation Education | University of Pittsburgh | Atrial Fibrillation (AF) | 06/25 | 07/25 | | |
| Recruiting | N/A | 2650 | Europe, Canada, Japan, US, RoW | Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC | Abbott Medical Devices | Atrial Fibrillation, Stroke, Bleeding | 08/27 | 08/30 | | |
| Bovbjerg, Dana H |
| Terminated | N/A | 8 | US | Dietary Intervention, Physical Activity Intervention | University of Pittsburgh, National Cancer Institute (NCI) | Bladder Cancer, Telomere Shortening, Colorectal Adenoma | 12/20 | 10/24 | | |
| Recruiting | N/A | 307 | US | CST-PSP, Coping Skills Training for Persistent Post-Surgical Pain, General health education | Duke University, University of Pittsburgh Medical Center | Coping Skills Training for Persistent Post-Surgical Pain, General Health Education | 04/25 | 04/25 | | |
| Smith, Anson Jay C |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
|
|
| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
| Singh, Michael |
C-TRACT, NCT03250247: Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The Trial) |
|
|
| Recruiting | N/A | 250 | US | Stents | Washington University School of Medicine, Ontario Clinical Oncology Group (OCOG), Massachusetts General Hospital, Saint Luke's Mid America Heart Institute | Deep Vein Thrombosis, Venous Stasis, Venous Insufficiency, Venous Leg Ulcer, Venous Reflux, Post Thrombotic Syndrome | 01/26 | 04/26 | | |
SSB 11-02, NCT02777528: Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (Zone 0/1) |
|
|
| Active, not recruiting | N/A | 150 | Japan, US | GORE® TAG® Thoracic Branch Endoprosthesis, Revascularization Procedure | W.L.Gore & Associates | Aortic Aneurysm, Thoracic, Aorta, Lesion | 03/24 | 03/28 | | |
| Recruiting | N/A | 300 | US | TREO Abdominal Stent-Graft System | Bolton Medical | Abdominal Aortic Aneurysm | 07/27 | 07/27 | | |
| Manager, Project |
| Recruiting | 3 | 200 | Canada | Magnesium sulfate and then Digoxin, Amiodarone | Sunnybrook Health Sciences Centre, Sunnybrook Research Institute | Atrial Fibrillation New Onset | 10/25 | 04/26 | | |
| Recruiting | 3 | 4514 | US | nasal antimicrobial photodisinfection therapy | Ondine Biomedical Inc. | Surgical Site Infections, Surgical Wound Infection, Infections, Anti-Infective Agents | 07/25 | 08/25 | | |
| Recruiting | 2 | 81 | Europe, US, RoW | Danvatirsen, ISIS 481464, AZD9150, Pembrolizumab, Keytruda | Flamingo Therapeutics NV | HNSCC | 05/25 | 05/26 | | |
NCT05714657: Shortened Course Adjuvant Radiotherapy Following TORS |
|
|
| Recruiting | 2 | 104 | US | Shortened Course Adjuvant Radiotherapy Following TORS | Abramson Cancer Center at Penn Medicine | HPV-Associated Oropharyngeal Squamous Cell Carcinoma | 12/25 | 04/26 | | |
| Recruiting | 2 | 30 | US | Hypofractionated Whole Pelvis Proton Therapy with Brachytherapy Boost | Abramson Cancer Center at Penn Medicine | Prostate Cancer | 01/26 | 12/31 | | |
| Recruiting | 2 | 25 | US | Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) | Abramson Cancer Center at Penn Medicine | Cervical Cancer, Uterine Cancer, Endometrial Cancer | 05/26 | 11/26 | | |
TRAK-ER, NCT04985266 / 2020-004022-36: A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer |
|
|
| Recruiting | 2 | 1100 | Europe | Palbociclib 125Mg Tab, Fulvestrant injection, Tamoxifen, Letrozole, Exemestane, Anastrozole | Royal Marsden NHS Foundation Trust, Pfizer, AstraZeneca, Institute of Cancer Research, United Kingdom, UNICANCER, Gustave Roussy, Cancer Campus, Grand Paris, Invitae Corporation | ER+ Breast Cancer, HER2-negative Breast Cancer | 09/27 | 09/30 | | |
| Completed | 1/2 | 116 | Europe | DMX-1002, Ibogaine Hydrochloride, Placebo, Microcrystalline cellulose | atai Therapeutics, Inc., MAC Clinical Research, ERT: Clinical Trial Technology Solutions, Hammersmith Medicines Research | Opiate Withdrawal Syndrome | 01/24 | 01/24 | | |
| Recruiting | 1/2 | 403 | US | FMC-376 | Frontier Medicines Corporation | Advanced Solid Tumors With KRAS G12C Mutations, Solid Tumor, Adult, Unresectable Solid Tumor, Metastatic Solid Tumor, Non Small Cell Lung Cancer, Colorectal Cancer, KRAS G12C, Pancreatic Cancer | 10/27 | 04/28 | | |
NCT05450549: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL919 in Healthy Participants |
|
|
| Completed | 1 | 47 | Europe | DNL919, Placebo | Denali Therapeutics Inc., Takeda | Healthy Participant | 06/23 | 06/23 | | |
NCT03832985: Pediatric Reporting of Adult-Onset Genomic Results |
|
|
| Completed | 1 | 427 | US | Receive an adult-onset result, Receive a pediatric-onset result, Control - No Result | Geisinger Clinic, National Human Genome Research Institute (NHGRI) | Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome, Familial Hypercholesterolemia | 10/24 | 10/24 | | |
MV371 LAI FiH, NCT06558643: Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy Participants |
|
|
| Recruiting | 1 | 24 | Europe | MMV371 LAI, Placebo for MMV371 | Medicines for Malaria Venture, Quotient Sciences, The Doctors Laboratory | Malaria,Falciparum | 03/25 | 03/25 | | |
NCT06639724: Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer |
|
|
| Recruiting | 1 | 36 | US | Fostamatinib in combination with chemotherapy (gemcitabine and nab-paclitaxel) | University of California, San Diego, Rigel Pharmaceuticals | Pancreatic Ductal Adenocarcinoma (PDAC) | 06/27 | 12/28 | | |
NCT06586255: Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer |
|
|
| Recruiting | 1 | 10 | US | Concurrent Immunotherapy and Radiation Therapy | Abramson Cancer Center at Penn Medicine | Urothelial Carcinoma Bladder, Bladder Cancer | 04/27 | 04/27 | | |
| Recruiting | 1 | 108 | US | Psilocybin, Psilocybine, Psilocibin, Filament Health Psilocybin, PEX010, Transcutaneous auricular Vagus Nerve Stimulation (taVNS), Psychosocial Support Alone, Sham taVNS | University of Wisconsin, Madison, Tiny Blue Dot Foundation | Healthy, Psychedelic Experiences, Vagus Nerve Stimulation | 11/27 | 01/28 | | |
NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing |
|
|
| Recruiting | N/A | 260 | Canada | FGFR Testing | Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada | Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma | 03/25 | 05/25 | | |
| Recruiting | N/A | 192 | RoW | Focused-PPC Care, Usual Care | University of Notre Dame, Savana Signatures, Indiana University School of Medicine | Postpartum Care | 01/23 | 06/23 | | |
| Recruiting | N/A | 400 | Europe, Canada, RoW | Pacing | Population Health Research Institute, Canadian Institutes of Health Research (CIHR) | Calcium Release Deficiency Syndrome (CRDS) | 12/25 | 03/26 | | |
| Completed | N/A | 23 | US | | Pennington Biomedical Research Center, National Institute of General Medical Sciences (NIGMS) | Hiv, Lung Injury | 08/23 | 12/23 | | |
| Recruiting | N/A | 190 | US | Customized Adherence Enhancement (CAE), Enhanced Treatment as Usual (eTAU) | Case Western Reserve University, National Institute of Mental Health (NIMH) | Bipolar Disorder | 11/25 | 05/26 | | |
TECHWISE, NCT06664944: Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study |
|
|
| Recruiting | N/A | 1000 | US | | Aura | Mood, Depression Disorders, Anxiety Disorders, Sleep, Eating Disorders, Physical Activity, Loneliness, Stress | 12/25 | 12/25 | | |
| Recruiting | N/A | 500 | Canada | | Population Health Research Institute, Canadian Institutes of Health Research (CIHR) | Calcium Release Deficiency Syndrome | 12/50 | 12/50 | | |
| Not yet recruiting | N/A | 20 | US | Freedom Pursuit Robotic Platform | Abramson Cancer Center at Penn Medicine | Brain Cancer | 02/27 | 02/27 | | |
RERUN, NCT06809764: Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC |
|
|
| Not yet recruiting | N/A | 150 | RoW | No drug | Daiichi Sankyo | Non-small Cell Lung Cancer | 02/27 | 02/27 | | |
NCT06659900: Community Vital Signs (CVS): an Integrated Community-Based Approach to Identify Undiagnosed Hypertension in Nigeria |
|
|
| Not yet recruiting | N/A | 24000 | RoW | CORE Plus (+), CORE | Oregon Health and Science University, University of Nigeria Nsukka | Hypertension | 06/27 | 06/27 | | |
| Active, not recruiting | N/A | 110 | US | Novel Communication Intervention, Enhanced Usual Care Parent Education | Indiana University, National Cancer Institute (NCI) | End of Life, Communication, Cancer Metastatic | 04/25 | 04/25 | | |
| Not yet recruiting | N/A | 190 | US | Smoking outcomes | University of Oklahoma | Cigarillo Flavor | 02/29 | 06/29 | | |
| Recruiting | N/A | 400 | Europe | ctDNA | Royal Marsden NHS Foundation Trust, Massachusetts General Hospital, Natera, Inc. | Breast Cancer | 12/25 | 12/28 | | |
NCT05568264: Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit |
|
|
| Recruiting | N/A | 192 | US | Physical Therapy intervention | Shirley Ryan AbilityLab, Ann & Robert H Lurie Children's Hospital of Chicago, Northwestern University, Northwestern Medicine, University of Illinois at Chicago | Motor Delay, Premature Birth, Intraventricular Hemorrhage, Hypoxic-Ischemic Encephalopathy, Bronchopulmonary Dysplasia | 05/26 | 12/26 | | |
NCT01577251: The Radiation Oncology Registry and Biosample Repository |
|
|
| Recruiting | N/A | 8000 | US | | Abramson Cancer Center at Penn Medicine | Neoplasia | 12/30 | 12/30 | | |
| Doshi, Ankur |
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk |
|
|
| Active, not recruiting | 3 | 2749 | Europe, US, RoW | Orforglipron, LY3502970, Insulin Glargine | Eli Lilly and Company | Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease | 09/25 | 01/26 | | |
| Active, not recruiting | 3 | 14013 | Europe, Canada, US, RoW | Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, KJX839, Placebo in 1.5ml | Novartis Pharmaceuticals | Primary Prevention of Atherosclerotic Cardiovascular Disease | 04/29 | 04/29 | | |
NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease |
|
|
| Recruiting | 2 | 268 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Crohn's Disease | 09/26 | 07/27 | | |
NCT06254950: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis |
|
|
| Recruiting | 2 | 207 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Ulcerative Colitis | 09/26 | 08/27 | | |
NCT05936151: A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes |
|
|
| Recruiting | 2 | 120 | Europe, Canada, US | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Overweight or Obesity, CKD, Type 2 Diabetes | 11/25 | 11/25 | | |
NCT05569005: Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms. |
|
|
| Terminated | N/A | 715 | Europe, Japan, US, RoW | THS use, Tobacco Heating System 3.0, Cigarette, Smoking Abstinence | Philip Morris Products S.A. | COPD, Smoking, Tobacco Use | 09/24 | 09/24 | | |
| Guyette, Frank X |
| Completed | 2 | 200 | US | Cold Stored Platelets (CSP), Standard Care | Jason Sperry, United States Department of Defense | Trauma, Hemorrhage | 10/23 | 11/23 | | |
| Policastro, Patricia |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
|
|
| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
| Low, Carissa A |
| Completed | 1 | 81 | US | Mindfulness, Coping | University of Pittsburgh, National Institutes of Health (NIH), National Center for Complementary and Integrative Health (NCCIH) | Stress, Mindfulness, Early Life Adversity | 05/24 | 05/24 | | |
| Recruiting | N/A | 25 | US | Behavioral Activation, Behavioral Intervention, Behavior Modification, Behavior or Life Style Modifications | University of Pittsburgh | Advanced Cancer, Cancer | 04/25 | 04/25 | | |
NCT04651452: Writing Interventions in Breast Cancer Patients Taking Aromatase Inhibitors |
|
|
| Recruiting | N/A | 250 | US | Value Affirmation, Reflective Journaling | Carnegie Mellon University, National Cancer Institute (NCI) | Breast Cancer | 12/25 | 12/25 | | |
| Castillo, Manuel J |
| Recruiting | N/A | 200 | Europe, Canada, US | AVP III | Abbott Medical Devices | Paravalvular Aortic Regurgitation | 07/25 | 06/26 | | |
| Recruiting | N/A | 750 | Europe, Canada, US, RoW | Corvia Atrial Shunt System / IASD System II, Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE) | Corvia Medical | Heart Failure, Heart Failure, Diastolic | 05/25 | 03/31 | | |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
|
|
| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study |
|
|
| Recruiting | N/A | 400 | Europe, US, RoW | AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy | Ancora Heart, Inc. | Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy | 12/26 | 12/30 | | |
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR |
|
|
| Recruiting | N/A | 300 | Europe, US | Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication | Cardiac Dimensions, Inc. | Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases | 12/26 | 12/30 | | |
| Sultan, Ibrahim |
| Active, not recruiting | N/A | 800 | Europe, Canada, US, RoW | Evolut™ PRO and Evolut™ PRO+ System (Evolut™ FX System for the addendum) | Medtronic Cardiovascular | Symptomatic Aortic Stenosis | 12/23 | 12/24 | | |
| Recruiting | N/A | 150 | US | Penditure™ Left Atrial Appendage (LAA) Exclusion System | Medtronic Cardiac Surgery | Left Atrial Appendage Exclusion | 11/25 | 02/29 | | |
| Active, not recruiting | N/A | 115 | US | AMDS | Artivion Inc., Syneos Health | Acute Aortic Dissection | 12/23 | 12/29 | | |
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement |
|
|
| Active, not recruiting | N/A | 1948 | Canada, US | ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL | Boston Scientific Corporation | Aortic Stenosis | 06/24 | 09/34 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
|
|
| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
|
|
| Enrolling by invitation | N/A | 1500 | Canada, US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
| Recruiting | N/A | 1100 | US | TEVAR, Guideline directed medical therapy and surveillance of dissection | Duke University, The University of Texas Health Science Center, Houston, State University of New York - Downstate Medical Center, Oregon Health and Science University, National Heart, Lung, and Blood Institute (NHLBI) | Type B Aortic Dissection | 06/30 | 06/30 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Recruiting | N/A | 200 | Europe, US | Thoraflex Hybrid, RelayPro NBS | Vascutek Ltd., Bolton Medical | Thoracic Diseases, Aortic Aneurysm, Aortic Dissection, Thoracic Aortic Aneurysm, Thoracic Aortic Dissection | 12/35 | 12/36 | | |
| Konopka, Kristin |
| Active, not recruiting | N/A | 800 | Europe, Canada, US, RoW | Evolut™ PRO and Evolut™ PRO+ System (Evolut™ FX System for the addendum) | Medtronic Cardiovascular | Symptomatic Aortic Stenosis | 12/23 | 12/24 | | |
| Active, not recruiting | N/A | 115 | US | AMDS | Artivion Inc., Syneos Health | Acute Aortic Dissection | 12/23 | 12/29 | | |
NCT05881278: XVIVO Heart Perfusion System (XHPS) with Supplemented XVIVO Heart Solution (SXHS) |
|
|
| Active, not recruiting | N/A | 141 | US | Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS) | XVIVO Perfusion | Heart Failure, Transplant; Failure, Heart | 11/25 | 11/29 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
| Ghodadra, Anish |
| Completed | N/A | 11 | US | Gel-Bead embolization | Anish Ghodadra | Knee Osteoarthritis | 10/23 | 10/23 | | |
MOTION, NCT05818150: GAE Using Embosphere Microspheres Vs Corticosteroid Injections for Treatment of Symptomatic Knee OA |
|
|
| Recruiting | N/A | 264 | NA | Embosphere Microspheres, Genicular artery embolization, Corticosteroid injection, Triamcinolone or methylprednisolone | Merit Medical Systems, Inc. | Knee Osteoarthritis | 04/26 | 10/27 | | |
| Balish, Kelsey |
NCT04606264: Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data |
|
|
| Recruiting | 3 | 2500 | US | Neuraxial Analgesia, Intrathecal morphine/hydromorphone, IT morphine/hydromorphine, Regional Block 1: Paravertebral, Nerve Block, Perphenazine, Aprepitant, Dimenhydrinate, Ondansetron 4 MG, Dexamethasone, Regional Block 2: QL1 | Jennifer Holder-Murray, Berry Consultants | Perioperative Optimization | 06/25 | 06/25 | | |
| Linger, Melissa Sanders |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
|
|
| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
| Kaynar, Murat |
| Active, not recruiting | N/A | 150 | US | +RxWell, -RxWell | University of Pittsburgh, National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA) | Mood Disorders, Anxiety, Depressive Symptoms, Depression, Anxiety Disorders, Anxiety Depression | 07/25 | 07/25 | | |
| Annunziato, Samantha |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
|
|
| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
| Plate, Johannes F |
NCT06489626: The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty |
|
|
| Not yet recruiting | 4 | 100 | US | Methylprednisolone 4 milligram Tab, Dexamethasone injection | F. Johannes Plate | Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative | 10/25 | 12/25 | | |
NCT06023238: Knee Prosthetic Joint Infection Antibiotic Elution |
|
|
| Not yet recruiting | N/A | 10 | US | Treatment of Chronic TKA PJI | University of Pittsburgh | Prosthetic-joint Infection, Arthroplasty Complications | 12/25 | 12/27 | | |
| Huang, Karen |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
|
|
| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
