University Hospital No.1, Collegium Medicum UMK, department of Paediatrics, Oncology, Hematology and Paediatric Transplantology Trials

University Hospital No.1, Collegium Medicum UMK, department of Paediatrics, Oncology, Hematology and Paediatric Transplantology	Welcome, Profile Billing Logout

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Locatelli, Franco

NCT02670564: ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)

Recruiting

1000

Europe

Pharmacogenomics, DNA analyses, Busulfan plasma level measurements

Swiss Pediatric Oncology Group, ALL SCTped Forum

Acute Lymphoblastic Leukemia

04/21

04/26

ALLELE, NCT03394365 / 2017-002949-30: Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants with Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy

	Data from ALLELE trial for post-transplant lymphoproliferative disease
	Dec 2021 - Dec 2021: Data from ALLELE trial for post-transplant lymphoproliferative disease

Recruiting

Europe, Canada, US, RoW

tabelecleucel, tab-cel®, ATA129, EBV-CTL

Atara Biotherapeutics

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications

08/25

06/27

NCT01728155: European Low and Intermediate Risk Neuroblastoma Protocol

Completed

685

Europe, RoW

chemotherapy

Instituto de Investigacion Sanitaria La Fe

LOW AND INTERMEDIATE PAEDIATRIC NEUROBLASTOMA AND NEONATAL SUPRARENAL MASSES

12/22

TRACE, NCT04832607 / 2018-000853-29: Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections

Recruiting

149

Europe

Multivirus (CMV, EBV, AdV)-specific T cells

Prof. Tobias Feuchtinger, European Commission, Simbec-Orion Group Ltd, Merthyr Tydfil, UK, Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, Germany, Leiden University Medical Center, LUMC, Leiden, The Netherlands, Centre Hospitalier Universitaire de Nancy, CHU, Vandoeuvre-Lès-Nancy, France, Ghent University Hospital, UZG, Ghent, Belgium, Ospedale Pediatrico Bambino Gesù, OPBG, Rome, Italy, Newcastle University, UNEW, Newcastle, UK, Vall d'Hebron Institute of Oncology (VHIO) and Banc de Sang I Teixits (BST), Barcelona, Spain

AdV Infection, EBV Infection, CMV Infection, Stem Cell Transplant Complications

06/24

12/24

AIEOP-BFM ALL 2017, NCT03643276 / 2016-001935-12: Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia -

Recruiting

5000

Europe, RoW

Blinatumomab, Bortezomib, Cyclophosphamide, Cytarabine, Daunorubicin, Myocet, Dexamethasone, Doxorubicin, Etoposide, Fludarabine Phosphate, Ifosfamide, 6-Mercaptopurine, Methotrexate, Pegaspargase, Prednisolone, Prednisone, Tioguanin, Vincristine, Vindesine, Erwinase

Martin Schrappe, Deutsche Krebshilfe e.V., Bonn (Germany)

Acute Lymphoblastic Leukemia, Pediatric

07/28

FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting

2/3

1800

Europe, Canada, RoW

VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin

St. Anna Kinderkrebsforschung, ALL SCTped Forum, European Society for Blood and Marrow Transplantation, ALL-BFM Study Group, Assistance Publique - Hôpitaux de Paris, Dutch Childhood Oncology Group, Swiss Pediatric Oncology Group, Australian & New Zealand Children's Haematology/Oncology Group

Acute Lymphoblastic Leukaemia

06/25

04/30

NCT04785547: ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT

Terminated

Europe, RoW

Blinatumomab, Blincyto

Prof. Christina Peters, Amgen

ALL, Childhood, Minimal Residual Disease

01/22

NCT04793919 / 2017-002383-40: Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Recruiting

Europe, RoW

Mylotarg, GO, Arsenic Trioxide, ATO, All-trans retinoic acid, ATRA

Associazione Italiana Ematologia Oncologia Pediatrica, AIEOP

Acute Promyelocytic Leukemia

10/25

10/27

XCGD-MOBI, NCT03055247 / 2015-002356-27: Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGD

Recruiting

Europe

Ibuprofen, Myelostim, Mozobil

IRCCS San Raffaele, Fondazione Telethon

Chronic Granulomatous Disease X-linked (X-CGD)

07/23

NCT03590171: International Study for Treatment of High Risk Childhood Relapsed ALL 2010

Recruiting

250

Europe, RoW

Bortezomib

Charite University, Berlin, Germany, Australian & New Zealand Children's Haematology/Oncology Group, St. Anna Kinderkrebsforschung, CCRI (co-sponsor, Austria), European Organisation for Research and Treatment of Cancer - EORTC, University Hospital Motol (Co-Sponsor Czech Republic), Copenhagen University Hospital, Rigshospitalet (co-sponsor, Denmark), Turku University Central Hospital (co-sponsor, Finland), Centre Hospitalier Universitaire de Nice, Our Lady's Chilrden's Hospital (Co-Sponsor Ireland), Tel Aviv Sourasky Medical Centre (Co-Sponsor Israel), Ospedale Pediatrico Bambino (co-sponsor, Italy), Prinses Máxima Centrum (Co-Sponsor Netherlands), Oslo University Hospital (co-sponsor, Norway), Medical University of Wroclaw (Co-Sponsor Poland), Instituto Português de Oncologia de Lisboa (co-sponsor, Portugal), Karolinska University Hospital Stockholm (co-sponsor, Sweden), Spanish Society of Pediatric Hematology and Oncology (SEHOP) (Co-Sponsor Spain), University Children's Hospital, Zurich, Central Manchester University Hospitals NHS Foundation Trust (co-sponsor, UK)

Acute Lymphoblastic Leukemia (ALL)

12/27

EBVision, NCT04554914 / 2020-000177-25: A Study to Evaluate Tabelecleucel in Participants with Epstein-barr Virus-associated Diseases

Jan 2023 - Dec 2023 : From P2 trial for Epstein-Barr virus-associated sarcoma

Recruiting

190

Europe, US

Tabelecleucel, tab-cel®, ATA129, EBV-CTLs

Atara Biotherapeutics

Epstein-Barr Virus (EBV)-associated Diseases, EBV+ Lymphoproliferative Disease with Primary Immunodeficiency (EBV+ PID LPD), EBV+ Lymphoproliferative Disease with Acquired (non-congenital) Immunodeficiency (EBV+ AID LPD), EBV+ Posttransplant Lymphoproliferative Disease in Central Nervous System (EBV+ CNS PTLD), EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications, EBV+ Sarcomas, Leiomyosarcoma

06/27

05/29

NCT03373097 / 2017-002475-26: Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk And/or Relapsed/refractory Neuroblastoma or Other GD2-positive Solid Tumors

Active, not recruiting

1/2

Europe

GD2-CART01

Bambino Gesù Hospital and Research Institute

Neuroblastoma, Neuroblastoma Recurrent, GD2-positive Solid Tumors, Osteosarcoma, Ewing Sarcoma, Sarcoma

12/26

12/27

NCT04501614 / 2019-002549-39: A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Terminated

1/2

Europe, US, RoW

Ponatinib, Chemotherapy Agents

Takeda, Takeda Development Center Americas, Inc.

Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL), Philadelphia Chromosome-Like ALL (Ph-like ALL)

12/23

07/24

NCT06521567: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Recruiting

1/2

Cobolimab, Dostarlimab

GlaxoSmithKline

Melanoma

08/28

11/30

NCT04787263: CD19-CAR_Lenti T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and DLBCL or PML

Recruiting

1/2

Europe

CD19-CAR_Lenti T cell

Bambino Gesù Hospital and Research Institute

Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, Primary Mediastinal Lymphoma

03/25

03/38

CD7-CAR01, NCT06064903: CD7-CAR-T Cells in Pediatric Relapsed/Refractory CD7+ T-ALL/LL

Recruiting

1/2

Europe

CD7-CART01

Bambino Gesù Hospital and Research Institute

T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

09/28

09/40

HEM-iSMART D, NCT05658640: HEM ISMART-D: Trametinib + Dexamethasone + Chemotherapy in Children with Relapsed or Refractory Hematological Malignancies

Recruiting

1/2

Europe, RoW

Trametinib, Dexamethasone, Cyclophosphamide, Cytarabine, Intrathecal chemotherapy

Princess Maxima Center for Pediatric Oncology, Innovative Therapies For Children with Cancer Consortium, IBFM, Fight Kids Cancer

Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

04/29

NCT06080191: Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

Recruiting

Europe

CD19-CAR_Lenti_ALLO

Bambino Gesù Hospital and Research Institute

B-cell Acute Lymphoblastic Leukemia

06/26

06/41

NCT05298995: GD2-CAR T Cells for Pediatric Brain Tumours

Recruiting

Europe

GD2-CART01 (iC9-GD2-CAR T-cells)

Bambino Gesù Hospital and Research Institute

Brain Tumor, Pediatric, Medulloblastoma, Childhood, Embryonal Tumor, High Grade Glioma, Diffuse Midline Glioma, Diffuse Intrinsic Pontine Glioma, Brain Tumor Adult

11/27

11/38

RAG1-SCID, NCT04797260: Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID

Recruiting

N/A

Europe, RoW

Gene therapy

Leiden University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development, Horizon 2020 - European Commission

Severe Combined Immunodeficiency Due to RAG1 Deficiency

12/29

HEMOGLOB-VAX, NCT05157256: Monitoring of Anti-SARS-CoV-2 (COVID 19) and Encapsulated Vaccination Patients With Thalassemic and Falcemic Syndromes

Active, not recruiting

N/A

1000

Europe

Società Italiana Talassemie ed Emoglobinopatie

SARS-CoV-2 Infection, Thalasemmie, SCD

12/30

Wysocki, Mariusz

FORUM, NCT01949129 / 2012-003032-22: Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting

2/3

1800

Europe, Canada, RoW

VP16, Etoposide, TBI, Thiotepa, Thio, Treosulfan, Treo, Fludarabine, Flu, Busulfan, Bu, ATG Thymoglobulin, ATG Thymo, Cyclophosphamide, Cy, Grafalon, Anti-human T-lymphocyte immunoglobulin

Acute Lymphoblastic Leukaemia

06/25

04/30

NCT04785547: ALL SCTped 2012 FORUM Add-on Study Blina Post HSCT

Terminated

Europe, RoW

Blinatumomab, Blincyto

Prof. Christina Peters, Amgen

ALL, Childhood, Minimal Residual Disease

01/22



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