4

337

RoW

Berberine plus lifestyle intervention, Placebo plus lifestyle intervention

China National Center for Cardiovascular Diseases

Obesity, Obesity, Abdominal, NAFLD

Active, not recruiting

4

8250

RoW

Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy

Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd.

Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases

04/25

04/25

Not yet recruiting

4

6500

RoW

Berberine plus lifestyle intervention, Placebo plus lifestyle intervention

China National Center for Cardiovascular Diseases

PreDiabetes, Abdominal Obesity, Hypertension, Dyslipidemias

12/26

12/26

Recruiting

3

310

RoW

Hyperthermic Intraperitoneal Chemotherapy, HIPEC, cytoreductive surgery, CRS, adjuvant chemotherapy, ACT

Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Henan Provincial People's Hospital, Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Peking University Cancer Hospital & Institute, Peking University People's Hospital, Cancer Hospital of Guizhou Province, Chinese PLA General Hospital, Hebei Medical University Fourth Hospital, The Second Hospital of Hebei Medical University, West China Second University Hospital, Peking Union Medical College Hospital, First Affiliated Hospital, Sun Yat-Sen University, Henan Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, The Third Affiliated Hospital of Guangzhou Medical University, Wuhan University, RenJi Hospital, Obstetrics & Gynecology Hospital of Fudan University, Southern Medical University, China, Fourth Affiliated Hospital of Guangxi Medical University, Shandong Cancer Hospital and Institute, Beijing Obstetrics and Gynecology Hospital, Chongqing University Cancer Hospital, Xinqiao Hospital of Chongqing, Wuhan Union Hospital, China, First Affiliated Hospital of Chongqing Medical University, Affiliated Cancer Hospital of Shantou University Medical College

Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma

07/21

07/23

Active, not recruiting

3

404

Europe, Canada, Japan, US, RoW

Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo

Chinook Therapeutics, Inc.

IgA Nephropathy, Immunoglobulin A Nephropathy

12/26

12/26

Recruiting

3

1380

RoW

Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin

Beijing Tiantan Hospital

Ischemic Stroke, Acute

12/25

12/26

Active, not recruiting

3

88

US

Cognitive Assessment, Quality-of-Life Assessment, Quality of Life Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy

M.D. Anderson Cancer Center, National Cancer Institute (NCI)

Metastatic Malignant Neoplasm, Metastatic Malignant Neoplasm in the Brain

09/25

09/25

Active, not recruiting

2

60

US

Computed Tomography, CAT, CAT Scan, Computerized Axial Tomography, computerized tomography, CT, CT SCAN, tomography, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Thermal Ablation Therapy, thermal ablation

M.D. Anderson Cancer Center, National Cancer Institute (NCI)

Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Neoplasm of Unknown Primary, Metastatic Melanoma, Prostate Carcinoma Metastatic in the Bone, Sarcoma, Solid Neoplasm, Spinal Cord Compression, Stage IV Breast Cancer AJCC V6 and V7, Stage IV Lung Non-Small Cell Cancer AJCC V7, Thyroid Gland Carcinoma

08/25

08/25

Terminated

2

6

RoW

Infigratinib, BGJ398, BBP-831

LianBio LLC

Gastric Cancer, Gastroesophageal Junction Adenocarcinoma

05/24

05/24

Recruiting

2

29

RoW

carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy

Jian Chen

Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect

06/25

06/26

Recruiting

2

55

RoW

Proton radiotherapy, combined platinum based chemotherapy

Jian Chen

Thymus Epithelial Tumor, Proton Radiotherapy, Radiation Toxicity

02/27

02/27

Active, not recruiting

2

49

US

Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery

M.D. Anderson Cancer Center, National Cancer Institute (NCI)

Clinical Stage IV Cutaneous Melanoma AJCC V8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC V8

08/26

08/26

Active, not recruiting

2

55

US

Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery

M.D. Anderson Cancer Center, National Cancer Institute (NCI)

Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8

12/26

12/26

Not yet recruiting

2

34

NA

Hetrombopag

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Thrombocytopenia

07/25

07/25

Recruiting

1/2

180

RoW

MG-K10, Placebo

Shanghai Mabgeek Biotech.Co.Ltd

Asthma

12/23

06/24

Not yet recruiting

1

10

RoW

β-globin restored autologous HSC

BGI-research, Shenzhen Children's Hospital

β-Thalassemia Major

11/22

11/24

Recruiting

N/A

200

RoW

Needle-free injector, Insulin pen

Second Affiliated Hospital, School of Medicine, Zhejiang University

T2DM (Type 2 Diabetes Mellitus), Needle-free Injector, Time in Range

12/22

12/22

Not yet recruiting

N/A

710

RoW

Intensive BP Arm, Control of SBP to <120 mmHg, Standard BP Arm, Control of SBP to <140 mmHg

China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, People's Republic of China

Blood Pressure

09/23

09/23

Recruiting

N/A

165

RoW

Dengzhanxixin Capsule plus Placebo Capsule, Placebo

China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medial Sciences, Shenzhen, Shenzhen

Diabetes, Hypertension, Hypercholesterolemia

12/23

12/23

Recruiting

N/A

2242

RoW

Epidemiological questionnaire and Functional Dyspepsia Symptom Diary（FDSD）

Shanghai Jiao Tong University School of Medicine

Helicobacter Pylori Infection, Dyspepsia

05/25

05/25

Not yet recruiting

N/A

175

RoW

Chinese University of Hong Kong

Recurrent Miscarriage

01/26

01/27

Recruiting

N/A

470

RoW

Non-interventional

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Amoy Diagnostics Co., LTD

Exploring the Correlation of HRD Score Pairs with the Prognosis of Chinese Ovarian Cancer Patients and the Outcome of Maintenance Therapy with PARPi

01/25

07/26

Recruiting

N/A

216

RoW

Baduanjin, Brisk walking

China National Center for Cardiovascular Diseases

Elevated Blood Pressure

12/24

12/25

Recruiting

N/A

50

RoW

Jing Li, Nanjing Shihejiyin Technology, Inc.

Ovarian Cancer Stage IV, Ovarian Cancer Stage III

08/25

08/25

Recruiting

N/A

720

RoW

Chinese University of Hong Kong

IVF

07/27

01/28

Not yet recruiting

N/A

300

NA

Neonatal hyperbilirubinemia

Shanghai First Maternity and Infant Hospital

Jaundice, Neonatal

09/22

09/22

Recruiting

3

600

Europe, Canada, Japan, US, RoW

Pirtobrutinib, LOXO-305, LY3527727, Venetoclax, Venclexta, Venclyxto, Rituximab, Rituxan, MabThera, Truxima, Riabni, Ruxience

Loxo Oncology, Inc., Eli Lilly and Company

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

04/26

01/27

Recruiting

N/A

42

RoW

Ortho-k lenses, Orthokeratology lens, RLRL, Repeated low-level red-light therapy

Zhongshan Ophthalmic Center, Sun Yat-sen University, The Second People's Hospital of Foshan, Tianjin Medical University Eye Center

Myopia, Progressive, Refractive Errors, Eye Diseases

06/22

06/22

Active, not recruiting

N/A

264

RoW

Low-level Red-light Therapy

Zhongshan Ophthalmic Center, Sun Yat-sen University, Shenzhen Children's Hospital, The Second People's Hospital of Foshan, Xiangya Hospital of Central South University

Myopia, Refractive Errors, Eye Diseases

12/22

12/22

Completed

3

514

RoW

HLX14, Prolia®

Shanghai Henlius Biotech, Shanghai Henlius Biotech, Inc.

Postmenopausal

12/23

07/24

Recruiting

N/A

3800

RoW

No intervention

Children's Hospital of Fudan University, Shengjing Hospital, China Medical University, Beijing Children's Hospital, Inner Mongolia Maternity and Child Health Care Hospital, Shanxi Provincial Maternity and Children's Hospital, Qilu Children's Hospital of Shandong University, The Affiliated Hospital of Qingdao University, Yantai Yuhuangding Hospital, Shanghai Children's Medical Center, Shanghai First Maternity And Infant Hospital, Tongji University, The First Affiliated Hospital with Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, The First Affiliated Hospital of USTC, Anhui Provincial Children's Hospital, Yuying Children's Hospital of Wenzhou Medical College, Ningbo Women & Children's Hospital, QuanZhou Women and Children's Hospital, Xiamen Maternity and Child Health Care Hospital, The First Affiliated Hospital of Zhengzhou University, Children's Hospital of Zhengzhou University, Hubei Maternity and Child Health Care Hospital, Hunan Children's Hospital, Foshan Maternity and Child Health Care Hospital, Maoming Maternity and Child Health Care Hospital, The Maternity and Child Health Care Hospital of Guangxi Zhuang Autonomous Region, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, Gansu Provincial Maternity and Child-Care Hospital, First Affiliated Hospital of Xinjiang Medical University, Xinjiang People's Hospital, Chengdu Women and Children's Medical Center, Guizhou Maternity and Child Health Care Hospital, The Affiliated Hospital of Zunyi Medical College

Bronchopulmonary Dysplasia

06/22

12/22

Recruiting

N/A

300

RoW

Neck management

Huashan Hospital

Oral Cancer, Lymph Node Metastasis

09/26

09/28

Recruiting

4

194

RoW

Icodextrin Peritoneal Dialysis Solution, Hypertonic Dextrose solution

First Affiliated Hospital, Sun Yat-Sen University, Baxter Healthcare Corporation

Peritoneal Dialysis

04/25

12/25

Recruiting

N/A

42

RoW

Ortho-k lenses, Orthokeratology lens, RLRL, Repeated low-level red-light therapy

Zhongshan Ophthalmic Center, Sun Yat-sen University, The Second People's Hospital of Foshan, Tianjin Medical University Eye Center

Myopia, Progressive, Refractive Errors, Eye Diseases

06/22

06/22

Recruiting

N/A

120

RoW

CMNT diet

State Key Laboratory of Subhealth Intervention Technology

Type 2 Diabetes

06/23

05/24

Active, not recruiting

N/A

195

RoW

Novel spectacle lens design, Spectacle lenses

SightGlass Vision, Inc.

Juvenile Myopia, Myopia

09/25

03/26

Completed

N/A

42

RoW

A standard image training set

Queen's University, Belfast

Training Group, Sensitivity

03/22

04/22

Recruiting

N/A

200

RoW

Pan-retinal photocoagulation laser treatment, PRP laser treatment

Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University, Queen's University, Belfast

Diabetic Retinopathy

10/23

10/23

Completed

N/A

1883

RoW

Spectacles

Queen's University, Belfast, L.V. Prasad Eye Institute, University of Zimbabwe, University of Ulster, New England College of Optometry, Peek Vision, Zimbabwe Optometric Association, Clearly, Christian Blind Mission

Hyperopia, Long Sight

07/23

07/23

Recruiting

N/A

2400

RoW

Eyeglasses, Glasses, Spectacle, Prescription slip

University of Minnesota, Innovations for Poverty Action, Peek Vision, Vision Action

Refractive Errors

Recruiting

N/A

10000

Europe, RoW

Spectacles, Glasses

Queen's University, Belfast, Zhongshan Ophthalmic Center, Sun Yat-sen University, Stanford University, New England College of Optometry, Clearly, Ningxia Medical University, He Eye Hospital, He University

Refractive Errors

07/27

07/27

Recruiting

N/A

1500

RoW

No interventions

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Sun Yat-sen University, Tungwah Hospital of Sun Yat-Sen University, Shunde Hospital of Southern Medical University, Zhongshan Ophthalmic Center, Sun Yat-sen University

Breast Neoplasm Female, Early-stage Breast Cancer, Radiomics, Axillary Lymph Node, Survival, Prosthesis

05/20

01/25

Recruiting

N/A

500

RoW

Ophthalmic examination, General Condition Examination

Zhongshan Ophthalmic Center, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University, Second Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial People's Hospital, Nanfang Hospital of Southern Medical University, Guangdong of China, Zhongshan People's Hospital, Guangdong, China, Guangdong Provincial People's Hospital, China, First People's Hospital of Foshan

Diagnostic Techniques, Ophthalmological, Liver Transplantation, Liver Cirrhoses

12/25

12/26

Recruiting

N/A

1000

RoW

A smartphone app for anemia screening

Sun Yat-sen University

Anemia

12/22

12/22

Recruiting

N/A

200

RoW

Sun Yat-sen University

Healthy, Vision; Disorder, Loss

12/22

04/23

Recruiting

N/A

60

RoW

Intelligent Language Model, control

Zhongshan Ophthalmic Center, Sun Yat-sen University

Medical Artificial Intelligence, Interdisciplinary Research, Self-Directed Learning

10/23

04/24

Completed

N/A

84

RoW

"Digital twin patient", Interaction with real patients

Sun Yat-sen University

Cataract, Glaucoma, Diabetic Retinopathy, Keratitis, Conjunctivitis

05/24

08/24

Recruiting

N/A

42

RoW

Zhongshan Ophthalmic Center, Sun Yat-sen University

Microsurgery, Binocular Visual Function, Nervous System

04/24

04/24

Not yet recruiting

N/A

1000

NA

Corticosteroids, immunosuppressors, biological agents

Sun Yat-sen University

Eye Involvement of Systemic Diseaes, Adverse Drug Effect on Eye, Artificial Intelligence

04/25

04/26

Recruiting

N/A

200

RoW

Sun Yat-sen University

Medical Artificial Intelligence, Medical Imaging

04/21

05/21