The Royal Marsden, The Royal Marsden NHS Foundation Trust
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 2 Trials 
5 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Allen, Steven
SELECT MDS-1, NCT04797780 / 2020-004528-40: Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome

Recruiting
3
550
Europe, Canada, US, RoW
Tamibarotene, SY-1425, Placebo, Azacitidine
Syros Pharmaceuticals
Myelodysplastic Syndromes
11/24
02/29
NCT02205762 / 2011-001699-20: LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis

Recruiting
2/3
1400
US
Prednisone, Vinblastine, Velban®, Vincaleukoblastine Sulfate, mercaptopurine, -Purinethol®, -6-MP, INDOMETHACIN, Methotrexate, Cytosine Arabinoside, Cytarabine, Ara-C, 2-chlorodeoxyadenosine, 2-CdA, Cladribin®, Leustatin®, hematopoietic stem cell transplantation (RIC-HSCT), Intravenous immunoglobulin, IVIG
North American Consortium for Histiocytosis, Histiocyte Society
Langerhans Cell Histiocytosis
07/25
07/25
NCT05828069: A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recruiting
2
48
Canada, US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, FDG-Positron Emission Tomography and Computed Tomography Scan, FDG PET/CT, Lumbar Puncture, LP, Spinal Tap, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Tovorafenib, BIIB 024, BIIB-024, BIIB024, DAY 101, DAY-101, DAY101, MLN 2480, MLN-2480, MLN2480, Ojemda, pan-RAF Kinase Inhibitor DAY101, TAK 580, TAK-580, TAK580
National Cancer Institute (NCI)
Recurrent Langerhans Cell Histiocytosis, Refractory Langerhans Cell Histiocytosis
05/25
05/25
COMPULSE, NCT04500262: Comparison Trial of Open-tip Pulsed Needle Biopsy and Conventional Core Biopsy in Axillary Lymph Nodes

Recruiting
N/A
479
Europe
Open-tip pulsed needle biopsy (NeoNavia Biopsy System), Core needle biopsy (CNB)
NeoDynamics AB
Breast Cancer
03/24
03/25
IRHDR, NCT02285582: International Rare Histiocytic Disorders Registry

Recruiting
N/A
300
Europe, Canada, US, RoW
Registry study
The Hospital for Sick Children
Rare Histiocytic Disorders (RHDs), Juvenile Xanthogranuloma (JXG), Reticulohistiocytoma (epithelioid Histiocytoma), Xanthoma Disseminatum (XD), Multicentric Reticulohistiocytosis (MRH), Systemic Juvenile Xanthogranuloma, Erdheim-Chester Disease (ECD), Multi-system Rosai-Dorfman Disease (RDD)
09/28
09/28

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