Walter Reed Army Institute of Research
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 9 Trials 
23 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Tribble, David
NCT04605783: Trial to Evaluate Dietary Supplements to Maintain Gut Health During Travel

Recruiting
N/A
866
Europe, US
Travelan®, Placebo
Henry M. Jackson Foundation for the Advancement of Military Medicine, Uniformed Services University of the Health Sciences
Diarrhea
01/25
04/25
Cummings, James F
NCT05067933: A Ph 2 Trial With an Oral Tableted COVID-19 Vaccine

Completed
2
66
US
VXA-CoV2-1.1-S, Oral Tableted Ad5 COVID-19 Vaccine, Placebo Tablets
Vaxart
COVID-19
05/22
08/23
NCT05626803: A Study to Determine the Safety and Immunogenicity of Bivalent GI.1 and GII.4 Vaccines in Healthy Volunteers

Active, not recruiting
2
135
US
Open label Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose, Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose, Bivalent GII.4/GI.1 medium dose vaccine 1×10 to the power 11 IU/dose, Placebo
Vaxart
Norovirus Infections
10/23
07/24
NCT06672055: A Study to Evaluate VXA-CoV2-3.1 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection

Recruiting
2
10000
US
VXA-CoV2-3.1, COMIRNATY®, Pfizer-BioNTech mRNA Vaccine
Vaxart
SARS-CoV2, COVID-19
01/26
01/26
G1-1 Challenge, NCT05212168: Norovirus Challenge Study

Completed
1/2
165
US
VXA-G1.1-NN, Placebo Tablets, Norovirus GI.1 Norwalk Virus Inoculum
Vaxart
Norovirus Infections
04/23
10/23
Thomas, Stephen J
COZI, NCT04468776: CBT-I or Zolpidem/Trazodone for Insomnia

Completed
4
155
US
Zolpidem, Ambien, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), SHUTi, Trazodone, Desyrel
California Pacific Medical Center Research Institute, Patient-Centered Outcomes Research Institute, University of Pittsburgh, University of Arizona, University of Virginia, University of Illinois at Chicago
Chronic Insomnia
06/24
06/24
NCT05823974: A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Active, not recruiting
1/2
1256
Europe, Canada, US, RoW
Flu mRNA, GSK4382276A, Control 1, Control 2
GlaxoSmithKline, CureVac
Influenza, Human
07/24
08/24
NCT05967455: Homologous Re-infection With Dengue 1 or Dengue 3

Completed
1
9
US
Dengue virus 1 Live Virus Human Challenge (DENV-1-LVHC), Dengue virus 3 Live Virus Human Challenge (DENV-3-LVHC)
State University of New York - Upstate Medical University, U.S. Army Medical Research and Development Command, Walter Reed Army Institute of Research (WRAIR)
Dengue
08/24
08/24
NCT03934255: Circadian Mechanisms Underlying Non-Dipping Blood Pressure in Blacks

Completed
N/A
32
US
Constant Routine Protocol
University of Alabama at Birmingham, American Heart Association
Circadian Rhythm, Blood Pressure
05/23
05/23
SCN-BP, NCT05656768: Sleep and Circadian Contributions to Nighttime Blood Pressure

Enrolling by invitation
N/A
70
US
Constant Routine Protocol
University of Alabama at Birmingham
Sleep, Circadian Rhythm, Blood Pressure, Hypertension
12/28
12/28
Spring, Michele D
NCT04228315: Biomarkers of P. Vivax Relapse

Recruiting
N/A
100
RoW
Primaquine
Armed Forces Research Institute of Medical Sciences, Thailand, University of North Carolina, Chapel Hill
Malaria, Vivax Malaria, Relapse, CYP2D6 Polymorphism
06/21
12/24
Moon, James
NCT04333459: Safety and Immunogenicity of a Hantaan Virus DNA Vaccine and a Puumala Virus DNA Vaccine, For The Prevention of Hemorrhagic Fever With Renal Syndrome

Recruiting
2a
132
US
Hataan DNA Vaccine/Puumala DNA Vaccine
U.S. Army Medical Research and Development Command
Hantaan Virus Nephropathy, Puumala Virus Nephropathy
12/22
12/23
NITRATE-TOD, NCT03088514: Investigation of Dietary Nitrate Effects in Hypertension-induced Target Organ Damage

Completed
2
149
Europe
Beetroot juice
Queen Mary University of London, Barts & The London NHS Trust
Hypertension
11/23
11/23
COVID19-HCW, NCT04318314: COVID-19: Healthcare Worker Bioresource: Immune Protection and Pathogenesis in SARS-CoV-2

Recruiting
N/A
731
Europe
COPAN swabbing and blood sample collection
University College, London, St. Bartholomew's Hospital, Royal Free Hospital NHS Foundation Trust, UCLH
Health Care Worker Patient Transmission, Coronavirus, Coronavirus Infections, Immunological Abnormality
04/21
04/22
NCT03860454: The Deep Phenotype of Lamin A/C Cardiomyopathy

Recruiting
N/A
150
Europe
University College, London, NIHR Rare Diseases Translational Research Collaboration, Barts Cardiovascular registry
Lamin A/C Gene Mutation, Dilated Cardiomyopathy, Familial
02/25
02/25
Paolino, Kristopher M
PROTECT, NCT06528457: Study to Examine the Effects of Oral Fenretinide

Recruiting
2
14
US
ISLA101, fenretinide, Dengue 1 Live Virus Human Challenge (DENV-1-LVHC), Placebo
Island Pharmaceuticals
Dengue
06/25
08/25
NCT06611111: Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease

Recruiting
1
44
US
Ceftriaxone (Rocephin®), Dextrose 5% (D5W)
State University of New York - Upstate Medical University, Steven & Alexandra Cohen Foundation
Post-Treatment Lyme Disease
03/26
03/26
Ratcliffe, Ruthie
NCT05309473: Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

Recruiting
N/A
44
US
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Walter Reed Army Institute of Research (WRAIR), Philips Healthcare
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
10/25
10/26
NCT04273841: Impact of Sleep Deprivation and Caffeine in Medical Professionals

Active, not recruiting
N/A
42
US
Military Energy Gum, Placebo Gum
Walter Reed Army Institute of Research (WRAIR)
Sleep Deprivation, Performance
10/26
10/28
Hutter, Jack N
NCT04296279: A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults

Recruiting
1
46
US
FMP014, ALFQ
U.S. Army Medical Research and Development Command, Walter Reed Army Institute of Research (WRAIR)
Vaccine Reaction
12/21
12/22
NCT04268420: A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults

Recruiting
1
46
US
FMP013, ALFQ
U.S. Army Medical Research and Development Command, Walter Reed Army Institute of Research (WRAIR)
Vaccine Reaction
07/23
12/23
Auslander, Margeaux V
NCT04997356: Hostile Bias Modification Training (HBMT) Study

Completed
N/A
165
US
Hostile Bias Modification Training, HBMT, Other training
Walter Reed Army Institute of Research (WRAIR)
Anger, Stress, Aggression
05/23
05/23
Riedy, Samantha
NCT05547880: CNS Correlates of Extended Sleep Restriction

Recruiting
N/A
18
US
[11C]ER176
Walter Reed Army Institute of Research (WRAIR), National Institute of Mental Health (NIMH), National Intrepid Center of Excellence
Sleep Restriction
03/25
03/25

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