| Liu, Ling |
NCT04845399: Phase III Expansion Trial for Determining the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A |
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| Completed | 3 | 101 | RoW | Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection | Zhengzhou Gensciences Inc, Jiangsu Gensciences lnc. | Hemophilia A | 06/21 | 06/21 | | |
NCT05003570: Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in ICU |
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| Recruiting | 3 | 138 | RoW | Remifentanil, Remifentanil Hydrochloride for Injection, Fentanyl, Fentanyl Citrate Injection | Southeast University, China | Analgesia | 12/22 | 12/22 | | |
NCT04973670: Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis |
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| Recruiting | 3 | 238 | RoW | Sivelestat sodium, Placebo | Southeast University, China | ARDS | 09/23 | 10/23 | | |
SPH3127-301, NCT05359068: Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension |
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| Completed | 3 | 957 | RoW | SPH3127 tablet, Valsartan | Shanghai Pharmaceuticals Holding Co., Ltd | Essential Hypertension | 12/23 | 12/23 | | |
ATNPC, NCT04718701: Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer |
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| Recruiting | 2 | 53 | RoW | Anlotinib+Toripalimab+Nab-paclitaxel, combination therapy | The First Affiliated Hospital with Nanjing Medical University | Pancreatic Neoplasm, Metastatic Pancreatic Cancer, Locally Advanced Pancreatic Adenocarcinoma | 02/23 | 02/23 | | |
NCT06038916: To Evaluate the Safety and Initial Efficacy of STSA-1002 Injection in Patients with Acute Respiratory Distress Syndrome |
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| Recruiting | 1/2 | 60 | RoW | STSA-1002 Injection Placebo, STSA-1002 Injection | Staidson (Beijing) Biopharmaceuticals Co., Ltd | Acute Respiratory Distress Syndrome | 08/25 | 09/26 | | |
NCT06529445: Food Effect and Relative Bioavailability Study of VC004 Capsules in Healthy Adult Subjects |
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| Completed | 1 | 84 | RoW | High Dose VC004 Capsules, Median Dose VC004 Capsules, Low Dose VC004 Capsules | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion | 08/24 | 08/24 | | |
NCT06619951: A Clinical Trial to Evaluate the Effects of Itraconazole or Rifampicin on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects |
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| Completed | 1 | 56 | RoW | VC004 and Itraconazole, VC004 and rifampicin | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced or Metastatic Solid Tumor | 10/24 | 10/24 | | |
NCT03842462: NHFOV vs NIPPV vs nCPAP in Preterm Infants With Respiratory Distress Syndrome |
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| Recruiting | N/A | 684 | RoW | nCPAP, NIPPV, NHFOV | Jiulongpo No.1 People's Hospital | Preterm Infant | 05/22 | 05/22 | | |
| Completed | N/A | 57 | RoW | driving pressure guided tidal volume | Southeast University, China | ARDS | 12/22 | 12/22 | | |
| Recruiting | N/A | 210 | RoW | blood mNGS (IDSeqTM Ultra); blood Culture | Southeast University, China, The First Affiliated Hospital with Nanjing Medical University, Northern Jiangsu Province People's Hospital | Sepsis | 12/22 | 12/22 | | |
NCT05372731: Recruitment Maneuver After Bronchoalveolar Lavage in ARDS Patients |
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| Not yet recruiting | N/A | 40 | NA | Recruitment Maneuver | Southeast University, China | Acute Respiratory Distress Syndrome | 12/22 | 12/22 | | |
NCT05219643: Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation |
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| Recruiting | N/A | 130 | RoW | NAVA, PSV | Southeast University, China, First Affiliated Hospital of Wannan Medical College | ARDS | 12/24 | 02/25 | | |
| Completed | N/A | 10 | RoW | different modes of mechanical ventilation | Southeast University, China | Acute Respiratory Failure | 08/23 | 08/23 | | |
NCT05549882: A Novel Index to Predict the Failure of High-flow Nasal Cannula in Patients With Acute Hypoxemic Respiratory Failure |
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| Recruiting | N/A | 504 | RoW | no intervention | Southeast University, China | Clinical Outcome | 08/23 | 08/23 | | |
NCT05073549: Optimizing Antibiotic Use in Neonatal Intensive Care Units in China |
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| Recruiting | N/A | 10000 | RoW | Collaborative Antimicrobial Stewardship Program (ASP) | Children's Hospital of Fudan University, China Medical Board | Neonates | 09/23 | 12/23 | | |
NCT05989971: The Effect of Continuous Renal Replacement Therapy on the Efficiency of Extracorporeal CO2 Removal |
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| Recruiting | N/A | 10 | RoW | continuous renal replacement therapy | Southeast University, China | Respiratory Failure With Hypercapnia | 12/23 | 12/23 | | |
NCT03345758: Long Term Outcome of Extracorporeal Membrane Oxygenation Patients in China |
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| Recruiting | N/A | 80 | RoW | outcome | Southeast University, China | Long-term Outcome, Extracorporeal Membrane Oxygenation | 12/23 | 12/23 | | |
NCT03763890: Post- End- Expiratory Pressure Affect the Alveolar Heterogeneity in Moderate and Sever ARDS Patients |
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| Recruiting | N/A | 40 | RoW | Post-end-Expiratory pressure | Southeast University, China | Ards | 12/23 | 12/23 | | |
NCT03182023: Long-term Outcome of Patients Treated With Extracorporeal Membrane Oxygenation |
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| Recruiting | N/A | 83 | RoW | | Southeast University, China | Long-term Outcome, Extracorporeal Membrane Oxygenation | 12/23 | 12/23 | | |
NCT05101694: Study on the Correlation Between Alveolar Macrophage-derived Autophagosomes and the Severity of Lung Injury in ARDS |
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| Recruiting | N/A | 60 | RoW | | Southeast University, China | ARDS | 12/23 | 12/23 | | |
NCT06213779: The Burden of Acute Respiratory Failure in Chinese ICUs: a National Cohort Study |
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| Recruiting | N/A | 1500 | RoW | | Southeast University, China | Acute Respiratory Failure, Acute Respiratory Distress Syndrome | 04/24 | 04/25 | | |
| Recruiting | N/A | 45 | RoW | position | Southeast University, China | Acute Respiratory Distress Syndrome, Prone Position, Tidal Volume | 02/25 | 04/25 | | |
NCT06393179: Epidemiology and Treatment Strategy of Open Respiratory Phenotype in Critically Ill Patients |
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| Recruiting | N/A | 60 | RoW | pressure-volume curve with a low-flow insufflation of 5 L/min | Southeast University, China | Mechanical Ventilation Pressure High, Critical Illness | 08/24 | 08/24 | | |
NCT06572280: Non-invasive Phrenic Nerve Stimulation in ARDS Patient |
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| Recruiting | N/A | 10 | RoW | PNS group | Southeast University, China | ARDS, Human, Ventilator-Induced Lung Injury, Diaphragm Injury | 12/24 | 01/25 | | |
NCT05207202: Effect of EIT-guided PEEP Titration on the Prognosis of Patients With Moderate to Severe ARDS |
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| Recruiting | N/A | 376 | RoW | electrical impedance tomography | Southeast University, China | Clinical Outcomes | 12/24 | 12/24 | | |
TRIPOD, NCT06795971: Effects of Face Mask Continuous Positive Airway Pressure vs. Noninvasive Ventilation vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: The Randomized Clinical Trial |
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| Not yet recruiting | N/A | 1300 | RoW | Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation | Southeast University, China | Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP) | 10/27 | 12/27 | | |
| Shen, Yang |
| Not yet recruiting | 2 | 20 | RoW | Envafolimab, Immunotherapy, Lenvatinib, Tyrosine kinase inhibitors, VP-16, Chemotherapy | Zhongda Hospital | Ovarian Cancer, Epithelial | 12/22 | 12/23 | | |
NCT06173037: RC88 in Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer |
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| Recruiting | 2 | 88 | RoW | RC88, RC88 for Injection | RemeGen Co., Ltd. | Primary Peritoneal Cancer, Fallopian Tube Cancer, Epithelial Ovarian Cancer | 06/26 | 12/26 | | |
NCT06241781: Autologous Tumor Infiltrating Lymphocytes (GT101 Injection) in Patients With Recurrent or Metastatic Cervical Cancer |
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| Recruiting | 2 | 64 | RoW | GT101 injection, Gemcitabine injection | Grit Biotechnology | Adult | 01/27 | 01/27 | | |
NCT06251947: Efbemalenograstim Alfa Injection for Ovarian or Cervical Cancer Receiving Chemotherapy Regimen |
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| Recruiting | 2 | 83 | RoW | Efbemalenograstim Alfa | Shandong University, Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Ovarian Cancer, Cervical Cancer | 06/26 | 12/26 | | |
NCT06652685: Molecular Subtype Combined with Early Minimal Residual Disease to Optimize the Treatment of Newly Diagnosed Acute Myeloid Leukemia |
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| Not yet recruiting | 2 | 218 | RoW | D5-PBCR(-) IA arm, D5-PBCR(+) IA+Venetoclax arm | Ruijin Hospital | Acute Myeloid Leukemia (AML) | 10/26 | 06/27 | | |
NCT05963100: Clinical Study of TCR-like CAR-T Cell Targeted MSLN in the Treatment of Ovarian Cancer |
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| Recruiting | 1/2 | 10 | RoW | TCR-like CAR-T | Zhongda Hospital | Safety and Efficacy of TCR-like CAR-T | 05/26 | 05/26 | | |
NCT06458361: Identification of Risk Factors and Construction of Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer |
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| Recruiting | N/A | 300 | RoW | Type of bowel resection, surgical complexity score, intraoperative blood loss, perioperative erythrocyte transfusion, type of anastomosis, Age, BMI, marital status, history of hypertension, history of diabetes mellitus | Zhongda Hospital | Ovarian Cancer | 06/24 | 11/24 | | |
NCT05734911: Effectiveness and Safety of Niraparib as First-line Maintenance Therapy for Ovarian Cancer: a Real-world Study |
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| Completed | N/A | 199 | RoW | Niraparib | Zhongda Hospital | Ovarian Neoplasms | 12/22 | 02/23 | | |
| Recruiting | N/A | 90 | RoW | Allogeneic Hematopoietic Stem Cell Transplantation, Chemotherapy, High-dose cytarabine | Ruijin Hospital | Acute Myeloid Leukemia | 09/26 | 02/28 | | |
NCT06458257: The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia |
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| Recruiting | N/A | 50 | RoW | Allogeneic Hematopoietic Stem Cell Transplantation, Chemotherapy | Ruijin Hospital | Acute Myeloid Leukemia | 12/26 | 12/28 | | |
NCT04695535: Chemotherapy With Anlotinib in Advanced Cervical Cancer |
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| Recruiting | N/A | 10 | RoW | | Yang Shen | Uterine Cervical Neoplasms | 05/22 | 06/22 | | |
| Liu, Liu Su |
| Completed | N/A | 69 | RoW | PEEP selection | Southeast University, China | ARDS, Human | 05/24 | 05/24 | | |
| ling, liu zi |
NCT05641909: Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in Intensive Care Unit |
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| Recruiting | 3 | 138 | RoW | Remifentanil, Remifentanil Hydrochloride for Injection, Fentanyl, Fentanyl Citrate Injection | Southeast University, China | Analgesia | 12/22 | 12/22 | | |
NCT04973670: Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis |
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| Recruiting | 3 | 238 | RoW | Sivelestat sodium, Placebo | Southeast University, China | ARDS | 09/23 | 10/23 | | |
NCT05219643: Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation |
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| Recruiting | N/A | 130 | RoW | NAVA, PSV | Southeast University, China, First Affiliated Hospital of Wannan Medical College | ARDS | 12/24 | 02/25 | | |
NCT05677984: Awaken Prone Positioning Ventinlation in COVID-19 Patients |
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| Completed | N/A | 409 | RoW | Awaken prone positioning ventilation | Southeast University, China | COVID-19 | 04/23 | 05/23 | | |
| Completed | N/A | 69 | RoW | PEEP selection | Southeast University, China | ARDS, Human | 05/24 | 05/24 | | |
| Recruiting | N/A | 45 | RoW | position | Southeast University, China | Acute Respiratory Distress Syndrome, Prone Position, Tidal Volume | 02/25 | 04/25 | | |
| Peng, Fei |
NCT04427371: The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis |
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| Recruiting | N/A | 100 | RoW | the levels of pyroptosis | Jianfeng Xie | Sepsis | 12/22 | 12/23 | | |
