| George, Mark S |
| Active, not recruiting | 2/3 | 34 | US | Transcranial Magnetic Stimulation (TMS) | Medical University of South Carolina, National Institute of Mental Health (NIMH) | Depression | 01/22 | 12/23 | | |
NCT06462820: SAINT for MDD in an Inpatient Setting Follow-on |
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| Not yet recruiting | 2/3 | 100 | US | Active SAINT Stimulation, Sham SAINT Stimulation | Magnus Medical | Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation | 12/25 | 02/26 | | |
NCT03693105: The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition |
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| Not yet recruiting | 2/3 | 100 | US | Active SAINT Stimulation, Sham SAINT Stimulation | Magnus Medical, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation | 12/25 | 02/26 | | |
| Completed | 1 | 3 | US | transcutaneous auricular vagus nerve stimulation, taVNS, Constraint induced movement therapy, CIMT | Medical University of South Carolina, National Center of Neuromodulation for Rehabilitation, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Infant Development, Hemiplegia, Constraint Induced Movement Therapy | 02/24 | 02/24 | | |
BabyStrong I, NCT04849507: BabyStrong Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Paired Bottle Feeding to Improve Oral Feeding |
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| Recruiting | 1 | 20 | US | transcutaneous auricular vagus nerve stimulation, taVNS, transcutaneous VNS | Medical University of South Carolina, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Infant Feeding Problems, taVNS | 07/24 | 08/24 | | |
NCT04279522: The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD) |
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| Active, not recruiting | N/A | 160 | US, RoW | Relivion®DP- Active, Relivion®DP- Sham | Neurolief Ltd. | MDD | 06/24 | 06/24 | | |
| Recruiting | N/A | 24 | US | Vagus Nerve Stimulation, Transcranial Magnetic Stimulation | Medical University of South Carolina | Depression | 06/24 | 07/24 | | |
NCT06426498: tFUS Induced Transient Scotoma for Individual Dosing |
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| Recruiting | N/A | 30 | US | Brainsonix Bx Pulsar machine tFUS | Medical University of South Carolina | Healthy | 05/25 | 08/25 | | |
| Not yet recruiting | N/A | 100 | US | Sham-stimulation, Active-stimulation | Abbott Medical Devices | Treatment Resistant Depression | 04/27 | 04/29 | | |
| Recruiting | N/A | 70 | US | Sham transcranial direct current stimulation, Individualized transcranial direct current stimulation, 2mA transcranial direct current stimulation, 4mA transcranial direct current stimulation | Medical University of South Carolina, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | tDCS, Motor Function | 12/24 | 04/25 | | |
| Recruiting | N/A | 154 | US, RoW | Frontoparietal Ultrabrief Right Unilateral (UBRUL-FP) electroconvulsive therapy, Temporoparietal Ultrabrief Right Unilateral (UBRUL-TP) electroconvulsive therapy | The George Institute, National Health and Medical Research Council, Australia, Ramsay Clinic Albert Road, Australia, Ramsay Clinic Lakeside, Australia, Ramsay Clinic Northside, Australia, Gold Coast Hospital and Health Service, Augusta University, Medical University of South Carolina, The University of New South Wales | Major Depressive Episode | 12/24 | 07/25 | | |
NCT04557891: Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD) |
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| Recruiting | N/A | 48 | US | Active LIFUP Treatment, BX Pulsar 1002, Sham LIFUP Treatment | University of California, Los Angeles, Massachusetts General Hospital, Medical University of South Carolina | Generalized Anxiety Disorder | 12/25 | 12/25 | | |
RECOVER, NCT03887715: A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression |
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| Recruiting | N/A | 6800 | US | Vagus Nerve Stimulation (VNS), VNS | LivaNova | Treatment Resistant Depression | 02/28 | 12/30 | | |
| Badran, Bashar W |
NCT05855369: Smell Training and Trigeminal Nerve Stimulation for COVID-related Smell Loss |
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| Recruiting | 2/3 | 180 | US | Trigeminal Nerve Stimulation (TNS), Transcutaneous Electrical Nerve Stimulation, Active Smell Training (ST), Olfactory Training, Placebo Smell Training (PBO) | Medical University of South Carolina, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Smell Dysfunction, Olfactory Disorder, Long COVID | 05/28 | 05/28 | | |
| Completed | 1 | 3 | US | transcutaneous auricular vagus nerve stimulation, taVNS, Constraint induced movement therapy, CIMT | Medical University of South Carolina, National Center of Neuromodulation for Rehabilitation, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Infant Development, Hemiplegia, Constraint Induced Movement Therapy | 02/24 | 02/24 | | |
BabyStrong I, NCT04849507: BabyStrong Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Paired Bottle Feeding to Improve Oral Feeding |
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| Recruiting | 1 | 20 | US | transcutaneous auricular vagus nerve stimulation, taVNS, transcutaneous VNS | Medical University of South Carolina, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Infant Feeding Problems, taVNS | 07/24 | 08/24 | | |
| Recruiting | 1 | 136 | US | Naloxone, Saline, Placebo | Medical University of South Carolina | Analgesia | 01/27 | 10/27 | | |
| Recruiting | N/A | 10 | US | transcutaneous auricular neurostimulation | Medical University of South Carolina | Depression, Anxiety | 12/24 | 12/24 | | |
NCT05986019: Transcranial Focused Ultrasound (tFUS) Modulation of Reward Network |
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| Recruiting | N/A | 10 | US | transcranial focused ultrasound (tFUS) | Medical University of South Carolina | Healthy | 07/24 | 12/24 | | |
| Recruiting | N/A | 30 | US | Transcutaneous Auricular Neurostimulation | Medical University of South Carolina | Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Ehlers-Danlos Syndrome | 07/25 | 07/25 | | |
| Recruiting | N/A | 96 | US | Transcutaneous Auricular Neruostimulation (tAN) | Medical University of South Carolina | Auricular Stimulation | 01/27 | 10/27 | | |
| Vieira, Noah |
| Recruiting | N/A | 24 | US | Vagus Nerve Stimulation, Transcranial Magnetic Stimulation | Medical University of South Carolina | Depression | 06/24 | 07/24 | | |
| Peng, Xiaolong |
| Recruiting | N/A | 20 | US | Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham Auricular Stimulation | Medical University of South Carolina | Stroke, Pain | 06/25 | 06/25 | | |
