| Ayoub, Jean-Pierre |
FINER, NCT04650581: Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Following Progression on First Line CDK 4/6 Inhibitor and Aromatase Inhibitor |
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| Active, not recruiting | 3 | 250 | Canada, RoW | Ipatasertib, Fulvestrant, Placebo | Canadian Cancer Trials Group, Hoffmann-La Roche | Breast Cancer | 12/24 | 12/26 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
ELAINE 3, NCT05696626: Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation |
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| Recruiting | 3 | 500 | Europe, Canada, US, RoW | Lasofoxifene in combination with abemaciclib, Fulvestrant in combination with abemaciclib | Sermonix Pharmaceuticals Inc. | Metastatic Breast Cancer | 04/27 | 04/28 | | |
| Wang, Yan |
NCT06256289: Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome |
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| Not yet recruiting | 4 | 50 | NA | Canagliflozin 100mg Tab, Invokana, Metformin Hydrochloride, Glucophage | Ping Li,MD | Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease | 04/25 | 04/25 | | |
NCT05042375: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer |
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| Recruiting | 3 | 450 | RoW | camrelizumab + famitinib, pembrolizumab, camrelizumab | Jiangsu HengRui Medicine Co., Ltd. | Non-small Cell Lung Cancer | 12/23 | 12/25 | | |
NCT06300177: D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure |
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| Recruiting | 3 | 522 | RoW | D-1553 Tablet, Docetaxel injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 10/26 | 12/27 | | |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
| Completed | 3 | 257 | RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Diabetes Type 2, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System Diseases | 07/24 | 07/24 | | |
NCT06738979: A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese Subjects |
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| Not yet recruiting | 3 | 408 | RoW | TQF3510 (Semaglutide Injection), Wegovy® | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Obesity | 07/26 | 08/26 | | |
TQB2450-AL2846-III-01, NCT05922345: Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy. |
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| Recruiting | 3 | 518 | RoW | TQB2450 injection, docetaxel injection matching placebo, AL2846 capsules, TQB2450 placebo, docetaxel injection, AL2846 matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non-small Cell Lung Cancer | 08/25 | 12/25 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
NCT04412564: A Study of TQ-B3101 Capsules in Subjects With Advanced Malignant Tumor |
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| Recruiting | 2 | 200 | RoW | TQ-B3101 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Advanced Malignant Tumor | 03/21 | 09/21 | | |
NCT04228926: Evaluating the Efficacy and Safety of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects |
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| Recruiting | 2 | 105 | RoW | ZKY001 eye drops 0.3g:0.006mg, shengfatai-eye drops, the Germinal Peptide eye drops, ZKY001 eye drops 0.3g:0.012mg, ZKY001 simulated eye drops, the placebo | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Corneal Defect | 12/21 | 12/21 | | |
NCT05148195: A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors |
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| Terminated | 2 | 86 | RoW | Envofolimab, BD0801, Docetaxel, Irinotecan, Leucovorin calcium, 5-Fluorouridine | Jiangsu Simcere Pharmaceutical Co., Ltd. | Advanced Solid Tumor | 07/23 | 07/23 | | |
NCT05420324: A Study to Assess YH003 in Combination with Pebolizumab and Albumin Paclitaxel Injection in Subjects with Unresectable/metastatic Mucosal Melanoma |
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| Completed | 2 | 20 | RoW | YH003, Pembrolizumab, albumin paclitaxel | Eucure (Beijing) Biopharma Co., Ltd | Mucosal Melanoma | 03/24 | 03/24 | | |
NCT06439381: Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps |
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| Recruiting | 2 | 120 | RoW | 300mg/600mg of TQH2722 injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Chronic Rhinosinusitis | 10/25 | 11/25 | | |
NCT06089278: A Clinical Study of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps. |
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| Recruiting | 2 | 160 | RoW | 300mg of TQH2722 injection, 600mg of TQH2722 injection, TQH2722 injection matching placebo | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Sinusitis | 05/25 | 05/25 | | |
NCT04993391: AP-L1898 Capsule in Patients With Non-small Cell Lung Cancer |
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| Recruiting | 1/2 | 156 | RoW | JS111(AP-L1898 Capsules) | Suzhou Junjing BioSciences Co., Ltd. | Lung Cancer | 06/24 | 08/24 | | |
NCT04434482: IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer |
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| Completed | 1/2 | 59 | US, RoW | IMP4297(senaparib), temozolomide | Impact Therapeutics, Inc. | Advanced Solid Tumours, Small Cell Lung Cancer | 04/24 | 04/24 | | |
NCT05416775: Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer |
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| Recruiting | 1/2 | 168 | RoW | SHR-8068；Adebrelimab, SHR-8068；adebrelimab and platinum-based chemotherapy, Adebrelimab；platinum-based chemotherapy | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Non-small Cell Lung Cancer | 06/26 | 06/26 | | |
NCT05126927: A PET Imaging Agent to Assess the Level of Tumor Tissue-infiltrating CD8 + T Cells in Patients With Solid Tumors |
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| Completed | 1 | 11 | RoW | 68Ga-NODAGA-SNA006 | SmartNuclide Biopharma, The First Affiliated Hospital of Soochow University | Solid Tumor | 01/22 | 08/22 | | |
NCT04711980: Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy |
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| Not yet recruiting | 1 | 402 | RoW | Mudan granule, Mudan particle, Placebo, Placebos | Fengmei Lian, Peking Union Medical College Hospital, Beijing Hospital, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Affiliated Hospital of Qingdao University, Chengdu University of Traditional Chinese Medicine, The Fourth People's Hospital of Chongqing, Zhengzhou Yihe Hospital Affiliated to Henan University, Zhu Xianyi Memorial Hospital of Tianjin Medical University, The Third Hospital of Xi'an, Huashan Hospital, Gansu Provincial People's Hospital, Shenzhen Hospital of Guangzhou University of Traditional Chinese Medicine, Affiliated Hospital of Changchun University of Chinese Medicine | Diabetic Peripheral Neuropathy Type 2 | 02/22 | 09/22 | | |
NCT05490264: [68Ga]Ga-NOTA-SNA002 (PD-L1 PET Tracer) for PET/CT in Patients With Solid Tumors |
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| Recruiting | 1 | 20 | RoW | [68Ga]Ga-NOTA-SNA002 | SmartNuclide Biopharma, The First Affiliated Hospital of Soochow University | Solid Tumor, Positron-Emission Tomography(PET) | 06/24 | 07/24 | | |
| Terminated | 1 | 24 | US | Alcohol, 80-proof Vodka Mixed Drinks | University of Florida, National Institute on Alcohol Abuse and Alcoholism (NIAAA), American Psychological Association | Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR) | 05/20 | 10/22 | | |
NCT06429241: Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula |
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| Recruiting | 1 | 8 | RoW | Mesenchymal Stem Cells (MSCs) | Jiangsu Topcel-KH Pharmaceutical Co., Ltd., The First Affiliated Hospital of Soochow University | Anal Fistula, Complex Perianal Fistulas, Crohn's Disease | 11/24 | 12/25 | | |
NCT06229301: A Study of Artificial Intelligence Assisted Small Incision Lenticule Extraction (SMILE) for Surgical Design and Influencing Factors |
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| Recruiting | N/A | 3000 | RoW | AI-predicted Nomogram | Tianjin Eye Hospital, Beihang University | Myopia, Myopic Astigmatism | 09/24 | 09/24 | | |
NCT04172168: Left Ventricular Free-wall Ruptrue After Acute Myocardial Infarction (LVFR-AMI) |
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| Recruiting | N/A | 17568 | RoW | Heart rupture | Xiamen Cardiovascular Hospital, Xiamen University | Acute Myocardial Infarction | 12/19 | 03/21 | | |
STMIK, NCT06233409: A Novel Sandwich Technique of Minimally Invasive Keratoplasty for Corneal Perforation |
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| Recruiting | N/A | 30 | RoW | | Tianjin Eye Hospital | Corneal Perforation, Corneal Stromal Lenticule,Sandwich Technique | 12/24 | 12/24 | | |
NCT06211218: Artificial Intelligence for Screening of Multiple Corneal Diseases |
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| Recruiting | N/A | 3000 | RoW | Cornea diseases diagnosed by artificial intelligence algorithm | Tianjin Eye Hospital | Deep Learning, Corneal Disease, Screening | 12/21 | 12/24 | | |
| Recruiting | N/A | 20 | RoW | Sodium Hyaluronate | Tianjin Eye Hospital, Tianjin University | Dry Eye | 12/21 | 03/22 | | |
NCT05967702: A 3-year Cross-sectional Assessment of the Tianjin Child and Adolescent Large-scale Eye Study |
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| Completed | N/A | 126810 | RoW | | Tianjin Eye Hospital | Myopia | 12/21 | 12/21 | | |
NCT06256770: Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia |
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| Recruiting | N/A | 176 | RoW | | Tianjin Eye Hospital | Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism | 09/24 | 12/24 | | |
NCT05748002: Evaluation of Morphology Abnormal Cornea Stability With Corneal Biomechanical |
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| Completed | N/A | 315 | RoW | Pentacam and Corvis ST | Tianjin Eye Hospital | Keratoconus, Stable | 12/22 | 12/22 | | |
NCT05336799: Prevalence and Environmental Factors for Myopia Among Chinese School-aged Children and Adolescent in Tianjin |
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| Recruiting | N/A | 500000 | RoW | | Tianjin Eye Hospital | Myopia, Refractive Errors | 12/22 | 12/25 | | |
NCT05362019: Effects of One-to-one Service on the Continuation and Satisfaction of Contraceptive Use. |
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| Not yet recruiting | N/A | 400 | RoW | Compound Norethisterone Enanthate Injection, One-to-one Service, Family Planning Service | National Research Institute for Family Planning, China | Contraception Behavior, Contraceptive Usage | 12/22 | 03/23 | | |
| Completed | N/A | 1152 | RoW | Non-invasive chromosome screening（NICS） | Peking University Third Hospital, Jinling Hospital, China, Reproductive Medical Center of Hebei Maternity Hospital, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, The First Medical Center of Chinese People's Liberation Army General Hospital, Shengjing Hospital, First Affiliated Hospital, Sun Yat-Sen University, Reproductive & Genetic Hospital of CITIC-Xiangya, Yikon Genomics Company, Ltd, Peking University Shenzhen Hospital, The Second Hospital of Hebei Medical University, West China Second University Hospital, Second Affiliated Hospital of Wenzhou Medical University, Third Affiliated Hospital of Zhengzhou University | Infertility, Chromosome Abnormality | 02/24 | 08/24 | | |
NCT05375110: NoYA RAISE Trial II (Radiofrequency Ablation-Based Interatrial Shunt for Heart Failure) |
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| Recruiting | N/A | 120 | RoW | NoYAâ„¢ Radiofrequency Interatrial Shunt System | Hangzhou NOYA MedTech Co. Ltm. | Heart Failure | 12/22 | 12/23 | | |
NCT05882383: Changes of Optical Quality During the Peak of the Covid-19 Pandemic |
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| Completed | N/A | 110 | RoW | | Tianjin Eye Hospital | Corneal Wavefront Aberration, SARS-CoV-2 | 01/23 | 01/23 | | |
NCT04918030: STaged Interventional Strategies for Acute ST-seGment Elevation Myocardial Infarction Patient With Multi-vessel Disease（STAGED） |
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| Recruiting | N/A | 1700 | RoW | In-hospital staged PCI, Percutaneous coronary intervention, Out-hospital staged PCI | Xiamen Cardiovascular Hospital, Xiamen University | STEMI, Multi Vessel Coronary Artery Disease, Percutaneous Coronary Intervention | 02/23 | 05/23 | | |
NCT06188351: Three Dimensional Navigation IntraCardiac Guidance Kit for Atrial Septal Puncture |
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| Recruiting | N/A | 136 | RoW | Three-Dimensional Navigation Atrial Septal Puncture, Conventional Atrial Septal Puncture | Tongji Hospital, Wuhan Greenrhythm Medical Technology Co., LTD | Atrial Fibrillation | 06/24 | 09/24 | | |
| Recruiting | N/A | 120 | RoW | Transcatheter aortic valve replacement | Genesis Medtech Corporation | Diseases of Aortic Valve, Aortic Regurgitation Disease | 05/23 | 05/24 | | |
NCT05607667: Clinical Trial in China for Aortic Valve Stenosis |
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| Recruiting | N/A | 53 | RoW | Transcatheter aortic valve replacement | Genesis Medtech Corporation | Diseases of Aortic Valve, Aortic Stenosis Disease | 05/23 | 05/23 | | |
NCT06152484: Evolution of a Novel Optical Coherence Tomography Based Index in Diagnosing Keratoconus |
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| Recruiting | N/A | 200 | RoW | Pentacam, Corvis ST and CASIA2 | Tianjin Eye Hospital | Scansys, Pentacam, Keratoconus, Subclinical Keratoconus | 02/24 | 04/24 | | |
NCT05497141: Dawneo Neoblazar® Transcatheter Tricuspid Valve Edge-to Edge Repair System Pivotal Clinical Trial in Patients With Severe Tricuspid Regurgitation |
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| Recruiting | N/A | 98 | RoW | Neoblazar® Transcatheter Tricuspid Valve Edge-to Edge Repair System | Xiamen Cardiovascular Hospital, Xiamen University | Tricuspid Regurgitation | 08/23 | 10/23 | | |
NCT06109636: Correlation Analysis Between Corneal Biomechanics and Anterior Segment |
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| Completed | N/A | 50 | RoW | Pentacam, Corvis ST and Casia2 | Tianjin Eye Hospital | Ciliary Muscle Thickness, Anterior Sclera Thickness, Corneal Biomechanics, CASIA2 | 10/23 | 10/23 | | |
NCT06119321: A Study of a Novel Scheimpflug Device in Diagnosing Keratoconus |
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| Active, not recruiting | N/A | 200 | RoW | Pentacam, Corvis ST and Scansys | Tianjin Eye Hospital | Scansys, Pentacam, Corvis ST, Keratoconus, Subclinical Keratoconus | 11/23 | 12/24 | | |
| Recruiting | N/A | 2132 | RoW | caFFR, Coronary Angiography-Derived Fractional Flow Reserve, FFR, Fractional Flow Reserve | Peking University First Hospital, Rainmed Ltd., Suzhou, China | Coronary Artery Disease, Coronary Stenosis, Myocardial Ischaemia, Coronary Circulation, Stable Angina Pectoris, Unstable Angina Pectoris, Asymptomatic Ischemia, Acute Myocardial Infarction, Percutaneous Coronary Intervention | 12/23 | 12/25 | | |
NCT04722796: HANGZHOU Solution in Bicuspid AS Undergoing TAVR |
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| Recruiting | N/A | 508 | RoW | TAVR with Venus A plus using supra-annular sizing and THV implantation technique (Hangzhou solution), Hangzhou solution, TAVR with Venus A plus using annular sizing and THV implantation technique, Traditional sizing strategy (Annulus based sizing strategy) | Second Affiliated Hospital, School of Medicine, Zhejiang University, Venus MedTech (HangZhou) Inc., First Affiliated Hospital Bengbu Medical College, Chinese PLA General Hospital, Fujian Medical University Union Hospital, Xiamen University Affiliated Cardiovascular Hospital, Guangdong People's Hospital, Zhengzhou Cardiovascular Hospital, The First Affiliated Hospital of Zhengzhou University, Hennan Provincial Chest Hospital, Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Central South University, Northern Jiangsu Province People's Hospital, The First Affiliated Hospital of Nanchang University, Second Affiliated Hospital of Nanchang University, The Affiliated Hospital of Qingdao University, Shanxi cardiovascular hospital, Tianjin Chest Hospital, Ning Bo First Hospital | Aortic Stenosis, Aortic Stenosis With Bicuspid Valve | 04/24 | 04/28 | | |
| Recruiting | N/A | 50 | RoW | Transseptal Transcatheter Mitral valve-in-valve Replacement | Xiamen Cardiovascular Hospital, Xiamen University | Bioprosthesis Failure, Mitral Stenosis With Insufficiency, Mitral Stenosis, Mitral Regurgitation, Heart Failure | 07/24 | 06/25 | | |
NCT06101888: Safety and Effectiveness of TaurusTrio™ Heart Valve System in Patients With Severe Aortic Regurgitation (AR) |
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| Recruiting | N/A | 116 | RoW | TaurusTrio™ Heart Valve System | Peijia Medical Technology (Suzhou) Co., Ltd. | Aortic Regurgitation | 07/24 | 07/29 | | |
NCT06567535: Treatment of Mandibular Bone Cyst by Navigation and Endoscopy |
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| Recruiting | N/A | 122 | RoW | Navigation and endoscopy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Jaw Cysts | 11/26 | 12/26 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
| Active, not recruiting | N/A | 51 | RoW | MitraClip procedure | Abbott Medical Devices | Mitral Regurgitation | 05/24 | 05/25 | | |
NCT06661499: An Observational Clinical Study on the Construction of an Artificial Neural Network Model for ICU Pneumonia |
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| Not yet recruiting | N/A | 600 | RoW | establish an artificial neural network model | Chinese Medical Association | Pneumonia | 12/27 | 12/27 | | |
TAILOR-TAVR, NCT05511792: Down Sizing Strategy (HANGZHOU Solution) vs Standard Sizing Strategy TAVR in Bicuspid Aortic Stenosis (Type 0) |
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| Recruiting | N/A | 206 | RoW | TAVR for BAV Using Down Sizing with the Evolut Pro platform, Down Sizing Strategy, TAVR for BAV Using Traditional Sizing strategy with the Evolut Pro platform, Standard Sizing Strategy | Second Affiliated Hospital, School of Medicine, Zhejiang University | Aortic Stenosis With Bicuspid Valve | 06/25 | 06/29 | | |
NCT06036563: Prospective Screening and Differentiating Common Cancers Using Peripheral Blood Cell-Free DNA Sequencing |
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| Recruiting | N/A | 3200 | RoW | | Air Force Military Medical University, China, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Tang-Du Hospital, The First Affiliated Hospital of Guangzhou Medical University, First Hospital of China Medical University, People's Hospital of Ningxia Hui Autonomous Region, Xinjiang Medical University, Guanxian People's Hospital | Cancer Diagnosis, LungCancer, Gastric Cancer, Liver Cancer, Colorectal Cancer, Esophagus Cancer, Breast Cancer, Pancreas Cancer | 08/25 | 12/25 | | |
| Recruiting | N/A | 120 | US | Counseling, mHealth | University of Florida, University of Miami, University of Louisville, Florida State University, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcohol Use | 09/26 | 09/26 | | |
NCT05486000: To Assess the Safety and Efficacy of the Atrial Shunt Implant System in the Treatment of Patients With Chronic Left Heart Failure |
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| Recruiting | N/A | 120 | RoW | Atrial shunt implant system | Morningside (Nantong) Medical Co.,Ltd, Xiamen Cardiovascular Hospital, Xiamen University | Left Heart Failure | 10/26 | 10/26 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
NCT05756959: Myopia Control Combined PBM With Myopic Defocus Lens in Children |
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| Recruiting | N/A | 304 | RoW | PBM, Low lever light therapy; low intensity red light therapy; low lever laser therapy; repeated red light therapy, Peripheral defocus spectacles, Myopic defocus spectacles for myopia control, Single vision spectacles, single vision glasseses for myopia correction lenses | Beijing Airdoc Technology Co., Ltd., The First People's Hospital of Xuzhou | Myopia, Progressive | 08/27 | 12/27 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
NCT04572594: Molecular Profiling and Molecular Labeling of Inflammatory Myofibroblastic Tumor |
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| Recruiting | N/A | 29 | RoW | | Sun Yat-sen University | Inflammatory Myofibroblatic Tumor | 01/21 | 01/21 | | |
| Not yet recruiting | N/A | 6262 | NA | face mask or not | Tianjin Eye Hospital | Dry Eye Syndromes | 02/21 | 02/21 | | |
| Recruiting | N/A | 36452 | RoW | outdoor time | Tianjin Eye Hospital | Myopia | 12/21 | 12/21 | | |
NCT05513664: Real-World Effectiveness of Osimertinib for Patients With Non-Small Cell Lung Cancer |
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| Not yet recruiting | N/A | 80 | RoW | Osimertinib | Shanghai JMT-Bio Inc., CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Locally Advanced or Metastatic Non-Small Cell Lung Cancer, EGFR Exon20 Insertion Mutations | 06/23 | 08/23 | | |
NCT05637827: The Initiating Factors of Myopia Among Primary and Secondary School Students in Tianjin |
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| Recruiting | N/A | 200 | RoW | No intervention | Tianjin Eye Hospital | Myopia; Refractive Error | 12/24 | 12/24 | | |
| Huang, Jian |
NCT05131841: Cipterbin Combined With Vinorelbine in the Treatment of HER2-positive MBC |
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| Recruiting | 4 | 60 | RoW | Cipterbin Combined With Vinorelbine | Zhejiang Cancer Hospital, Proswell Medical Corporation | Metastatic Breast Cancer | 12/22 | 12/22 | | |
CLOVER, NCT03926091: Study Comparing 4 Cycles With 6 Cycles of TC (Docetaxel+Cyclophosphamide) Adjuvant Chemotherapy for 1-3 Lymph Node Positive ER+/HER2- Early Breast Cancer |
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| Recruiting | 3 | 2172 | RoW | Docetaxel, docetaxel injection, Cyclophosphamide, Cyclophosphamide injection | Fudan University | Breast Cancer | 11/24 | 11/25 | | |
NCT05600322: Comparative Study of Hexvix Blue Light Cystoscopy and White Light Cystoscopy in the Detection of Bladder Cancer |
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| Completed | 3 | 158 | RoW | Hexaminolevulinate Hydrochloride, Hexvix, Richard Wolf Photodynamic Diagnostic Equipment (PDD) system, System Blue | Photocure, Jiangsu Yahong Meditech Co., Ltd aka Asieris, Richard Wolf GmbH, Tigermed-Jyton Co., Ltd. | Bladder Cancer | 07/23 | 07/23 | | |
NCT06241755: Clinical Trial for Evaluating the Efficacy and Safety of BCG for Therapeutic Use in the Prevention of Postoperative Recurrence of Medium/High-risk Non-muscle Invasive Bladder Cancer (NMIBC) |
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| Recruiting | 3 | 412 | RoW | BCG for Therapeutic Use, BCG | Chengdu CoenBiotech Co., Ltd, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Non-Muscle Invasive Bladder Cancer | 09/25 | 09/26 | | |
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer |
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| Active, not recruiting | 3 | 274 | RoW | BPI-16350, placebo, Fulvestrant | Betta Pharmaceuticals Co., Ltd. | Breast Cancer | 12/23 | 07/25 | | |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
JSKN003-302, NCT06079983: JSKN003 Versus Treatment Of Physician'S Choice For HER2-low, Unresectable and/or Metastatic Breast Cancer Subjects |
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| Not yet recruiting | 3 | 400 | RoW | JSKN003, Capecitabine tablets, Gemcitabine hydrochloride for injection, Vinorelbine tartrate injection, Paclitaxel for injection (albumin-bound type), Docetaxel injection, Eribulin mesylate injection | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Breast Cancer | 04/25 | 03/29 | | |
| Recruiting | 3 | 314 | RoW | Investigational drug: Recombinant Anti-HER2 Humanized Monoclonal Antibody - Monomethyl Auristatin F Conjugates for Injection (FS-1502), Control drug: Trastuzumab emtansine (Kadcyla, T-DM1) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | Breast Cancer | 07/25 | 01/26 | | |
| Active, not recruiting | 3 | 650 | Europe, Canada, Japan, US, RoW | Pirtobrutinib, LOXO-305, LY3527727, Ibrutinib | Loxo Oncology, Inc., Eli Lilly and Company | Chronic Lymphocytic Leukemia, Leukemia, Lymphocytic, Leukemia, B-cell, Small Lymphocytic Lymphoma | 02/25 | 08/28 | | |
NCT05075512: The Efficacy and Safety of Anlotinib Combined With Fulvestrant in Patients With Advanced Breast Cancer |
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| Recruiting | 2 | 40 | RoW | anlotinib, fulvestrant, AL3818 | Zhejiang Cancer Hospital | Breast Neoplasm Female | 08/23 | 08/26 | | |
NCT04799847: Catumaxomab in Patients With Non-Muscle-Invasive Bladder Cancer Who Have Failed or Are Intolerant to BCG Vaccine |
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| Recruiting | 1/2 | 161 | RoW | Catumaxomab | LintonPharm Co.,Ltd. | Bladder Cancer | 11/24 | 11/24 | | |
| Recruiting | 1/2 | 725 | RoW | JSKN003 | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Advanced Solid Tumor | 12/24 | 12/26 | | |
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NCT06001580: A Phase I Study of BR101 Injection Alone in Subjects With Advanced Solid Tumors |
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| Recruiting | 1 | 36 | RoW | BR101 | Zhe Jiang Hisun Bioray Bio-pharmaceu tical Co.Ltd | Advanced Solid Tumor | 12/23 | 06/26 | | |
NCT06672263: A Clinical Trial to Evaluate the Safety and Tolerability of TQB3911 Tablets in Patients With BCR::ABL Fusion Gene Positive Leukemia |
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| Not yet recruiting | 1 | 120 | RoW | TQB3911 tablets | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Chronic Myelogenous Leukemia | 09/26 | 12/26 | | |
NCT05106868: Acupuncture for Patients With Major Depressive Disorder |
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| Not yet recruiting | N/A | 123 | NA | acupuncture | Chengdu University of Traditional Chinese Medicine | Major Depressive Disorder | 12/22 | 06/23 | | |
VR-TSP, NCT06574451: Effectiveness and Safety of Adjuvant Software Based on Virtual Reality for Post-thoracoscopic Surgery Pain |
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| Recruiting | N/A | 215 | RoW | VR-assisted postoperative analgesia | Guangdong Provincial People's Hospital, Guang Dong Liang Zi Health Consulting Co., Ltd, Guang Dong, China., Tianjin Medical University General Hospital, Ruijin Hospital, Maoming People's Hospital | Acute Postoperative Pain, Video-assisted Thoracic Surgery, Virtual Reality | 04/25 | 04/25 | | |
NCT04948528: Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma Detection |
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| Recruiting | N/A | 490 | RoW | Active Comparator: Surgery Pathology or Cystoscopy, Active Comparator: Clinical Diagnosis | AnchorDx Medical Co., Ltd., Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Peking University First Hospital, Peking University Third Hospital, Peking Union Medical College Hospital, The Affiliated Hospital of Qingdao University, First Affiliated Hospital, Sun Yat-Sen University, Sir Run Run Shaw Hospital, The First Affiliated Hospital of Zhengzhou University | Upper Tract Urothelial Carcinoma | 06/23 | 12/23 | | |
NCT04744506: Targeted Resection of Axillary Metastatic Lymph Nodes After Breast Cancer Neoadjuvant Chemotherapy |
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| Not yet recruiting | N/A | 126 | RoW | Tissue Marker Clip, Carbon Nanoparticle Suspension Injection | Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Natural Science Foundation of China | Breast Cancer, Surgery, Lymph Node Metastases | 07/28 | 07/29 | | |
NCT04966949: Lateral Prostate Capsule Sparing Versus Nerve Sparing Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder for Bladder Cancer in the Male |
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| Not yet recruiting | N/A | 100 | RoW | lateral prostate capsule sparing or neurovascular bundles sparing | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 08/23 | 08/23 | | |
ONAC, NCT06155305: Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer |
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| Recruiting | N/A | 58 | RoW | Biopsy | Second Affiliated Hospital, School of Medicine, Zhejiang University | Organoids, Breast Cancer, Neoadjuvant Chemotherapy | 12/25 | 12/25 | | |
NCT06658080: Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer |
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| Recruiting | N/A | 90 | RoW | organoid drug test | Second Affiliated Hospital, School of Medicine, Zhejiang University | Breast Cancer Metastatic, Hydrothorax, Ascites, Organoids, Drug Evaluation | 10/26 | 10/27 | | |
NCT06741540: Effects of TDCS Intervention on Neoadjuvant Chemotherapy in Breast Cancer Patients with Mild to Moderate Depression |
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| Not yet recruiting | N/A | 60 | NA | tDCS | Second Affiliated Hospital, School of Medicine, Zhejiang University | Breast Cancer | 12/26 | 12/26 | | |
NCT04966975: Effect and Prognosis of Immunohistochemical Biomarkers Changes in Patients With Bladder Cancer After Neoadjuvant Chemotherapy |
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| Not yet recruiting | N/A | 60 | NA | neoadjuvant chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Shantou Central Hospital | Bladder Cancer | 08/22 | 08/22 | | |
NCT04966130: Effect of Urinary Indwelling Time on Early Continence After Robot-assisted Radical Cystectomy With Orthotopic Ileal Neobladder. |
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| Not yet recruiting | N/A | 96 | NA | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University | Muscle-Invasive Bladder Carcinoma | 08/22 | 08/22 | | |
NCT04966962: Establishment and Validation of an Early Diagnostic Model for Bladder Cancer Based on Serum and Urine Metabolomics |
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| Not yet recruiting | N/A | 180 | NA | serum and urine metabolomics | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 08/22 | 08/22 | | |
NCT04958343: Application and Clinical Effectiveness of Pelvic Reconstruction in Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder in the Male |
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| Not yet recruiting | N/A | 100 | RoW | pelvic reconstruction | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 07/23 | 07/23 | | |
NCT04958330: Lateral Prostate Capsule Sparing Versus Non Nerve Sparing Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder for Bladder Cancer in the Male |
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| Not yet recruiting | N/A | 100 | RoW | lateral prostate capsule sparing | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, The Seventh Affiliated Hospital, Sun Yat-sen University | Bladder Cancer | 07/23 | 07/23 | | |
NCT05018429: Nerve Sparing Versus Non Nerve Sparing Robot-assisted Radical Cystectomy-orthotopic Ileal Neobladder for Bladder Cancer in the Male |
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| Not yet recruiting | N/A | 100 | RoW | nerve sparing | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital, Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Shantou Central Hospital | Bladder Cancer | 09/23 | 09/23 | | |
| Li, Yongqiang |
TQB2102-II-04, NCT06767800: A Clinical Trial Evaluating TQB2102 for Injection in Combination With Benmelstobart/Penpulimab With or Without Capecitabine in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma |
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| Not yet recruiting | 2 | 168 | RoW | TQB2102 for injection+Benmelstobart, TQB2102 for injection+Benmelstobart+Capecitabine | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Gastroesophageal Adenocarcinoma | 09/26 | 09/27 | | |
| Recruiting | 1/2 | 364 | RoW | SHR-A1811 combined with Pyrotinib., SHR-A1811 combined with other antitumor therapies | Jiangsu HengRui Medicine Co., Ltd. | HER2-expressing Advanced Solid Tumors | 11/26 | 12/26 | | |
NCT06010901: A Clinical Study of TQB2618 Injection Monotherapy and Combination Regimen (With Penpulimab Injection ±Anlotinib Hydrochloride Capsules) in the Four or Later Lines of Treatment of Advanced Colorectal Cancer. |
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| Recruiting | 1 | 75 | RoW | TQB2618 injection, Penpulimab injection, Anlotinib hydrochloride capsules | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Colorectal Cancer | 03/25 | 07/25 | | |
| Hu, Chunhong |
| Active, not recruiting | 3 | 654 | Europe, Canada, Japan, US, RoW | Tucatinib, TUKYSA, ONT-380, ARRY-380, Trastuzumab, Herceptin, Herceptin Hylecta, Pertuzumab, Perjeta, Combination product: Trastuzumab + Pertuzumab, Phesgo, Placebo | Seagen Inc., Merck Sharp & Dohme LLC | HER2 Positive Breast Cancer | 05/25 | 10/27 | | |
| Recruiting | 1/2 | 500 | Europe, Canada, Japan, US, RoW | Oral repotrectinib (TPX-0005), repotrectinib | Turning Point Therapeutics, Inc., Zai Lab (Shanghai) Co., Ltd. | Locally Advanced Solid Tumors, Metastatic Solid Tumors | 02/28 | 02/28 | | |
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SMILE, NCT05113017: The Effectiveness and Safety of SBRT in the Treatment of Patients With MPLC After Surgery |
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| Recruiting | N/A | 40 | RoW | NO Intervention | Fang Wu, Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Hunan Cancer Hospital | The Efficacy and Safety of SBRT in MPLC | 12/24 | 12/24 | | |
