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6 Active 2 Inactive 8 All	Not yet recruiting Recruiting Enrolling by invitation Active, not recruiting Available No longer recruiting	Industry lead sponsor Industry collaborator Coop Other	US Canada Japan Europe RoW	N/A 1 2 3 4	Highlight changes:- Show only changed items Enrollment:

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Eng, Marvin H
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial	Recruiting	N/A	1247	Europe, Canada, US	Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System	Edwards Lifesciences	Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation	01/25	04/30
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement	Active, not recruiting	N/A	1948	Canada, US	ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL	Boston Scientific Corporation	Aortic Stenosis	06/24	09/34
SAVE, NCT04372381: Supra-Annular vs. Annular ValvEs for Small Annuli	Enrolling by invitation	N/A	150	US	Transcatheter aortic valve replacement (Edwards Sapien Ultra or Medtronic Evolut Pro	Marvin Eng, William Beaumont Hospitals	Aortic Valve Stenosis, Implantation, Heart Valve Prosthesis	11/24	06/25
MITRAL-II, NCT04408430: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).	Recruiting	N/A	210	US	Transseptal ViMAC, ViMAC	Mayra Guerrero	Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease	12/24	12/24
CLASP II TR, NCT04097145: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial	Recruiting	N/A	870	Canada, US	Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy	Edwards Lifesciences	Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease	12/24	03/29
NCT04198870: MitraClip REPAIR MR Study	Recruiting	N/A	500	Europe, Canada, US	MitraClip™ device implantation, Mitral Valve Repair Surgery	Abbott Medical Devices	Mitral Valve Regurgitation	04/26	04/34