| Chu, Michael |
| Recruiting | 3 | 3200 | Europe, Canada, US | Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center | Atrial Fibrillation, Stroke, Bleeding | 08/26 | 08/26 | | |
ACIT001/EXC002, NCT03938987: Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL) |
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| Recruiting | 1/2 | 63 | Canada | autologous CD19-directed chimeric antigen receptor (CAR) T-cells | University of Alberta, Alberta Cancer Foundation, Canadian Cancer Trials Group | Relapsed Non Hodgkin Lymphoma, Relapsed Adult ALL, Relapsed Pediatric ALL | 12/25 | 12/27 | | |
| Completed | N/A | 140 | Canada, US | DrugSorb-ATR system, Sorbent hemoperfusion system, Sham comparator | CytoSorbents, Inc | Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative | 08/23 | 08/23 | | |
| Completed | N/A | 40 | Canada | AMDS | Ascyrus Medical LLC., Artivion Inc. | Aortic Dissection, Intramural Hematoma | 08/19 | 03/24 | | |
| Active, not recruiting | N/A | 96 | Canada | | Horizon Health Network | Multiple Myeloma | 12/24 | 03/26 | | |
| Recruiting | N/A | 282 | Canada, US | Hypothermic circulatory arrest | Ottawa Heart Institute Research Corporation | Thoracic Aortic Disease | 02/25 | 09/25 | | |
| Recruiting | N/A | 182 | Canada | Hemiarch repair, Extended arch repair | University of Calgary | Aortic Dissection | 03/25 | 03/25 | | |
| Recruiting | N/A | 610 | Canada, US | Thoracic Aortic Surgery | Ottawa Heart Institute Research Corporation, University of Calgary | Ascending Aortic Aneurysm Enlargement, Ascending Aorta Aneurysm | 05/25 | 05/26 | | |
| Recruiting | N/A | 650 | Europe, Canada, Japan, US, RoW | Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT) | Medtronic Cardiovascular | Moderate Aortic Valve Stenosis | 02/26 | 12/34 | | |
| Recruiting | N/A | 842 | Canada, US | CardioGard Embolic Protection Cannula, Standard Aortic Cannula | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI) | Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease | 04/27 | 04/27 | | |
| Active, not recruiting | N/A | 4300 | Europe, Canada, Japan, US, RoW | Single arterial graft, Multiple arterial grafting | Weill Medical College of Cornell University, National Heart, Lung, and Blood Institute (NHLBI), Canadian Institutes of Health Research (CIHR) | Coronary Artery Disease, Heart Diseases | 06/27 | 01/30 | | |
PRIMARY, NCT05051033: Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds |
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| Recruiting | N/A | 450 | Europe, Canada, US | Mitral valve repair, Mitral valve surgery, Transcatheter edge-to-edge repair, TEER | Annetine Gelijns, National Heart, Lung, and Blood Institute (NHLBI) | Mitral Valve Regurgitation | 11/28 | 11/30 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
NCT05427370: The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C) |
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| Recruiting | N/A | 754 | Europe, Canada, US, RoW | Revascularization by PCI, Revascularization by CABG | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR), Weill Medical College of Cornell University | Coronary Artery Disease, Heart Failure Systolic | 04/29 | 12/29 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Fox, Stephanie |
| Active, not recruiting | 4 | 4107 | Canada | Prevena, Cefazolin, Vancomycin, Vancocin, standard wound dressing | Population Health Research Institute | Surgical Site Infections | 04/23 | 12/24 | | |
| Recruiting | 3 | 3200 | Europe, Canada, US | Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center | Atrial Fibrillation, Stroke, Bleeding | 08/26 | 08/26 | | |
| Recruiting | N/A | 15 | Europe, Canada, RoW | VenTouch System | Mardil Medical | Functional Mitral Regurgitation | 05/21 | 12/23 | | |
| Completed | N/A | 140 | Canada, US | DrugSorb-ATR system, Sorbent hemoperfusion system, Sham comparator | CytoSorbents, Inc | Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative | 08/23 | 08/23 | | |
| Recruiting | N/A | 842 | Canada, US | CardioGard Embolic Protection Cannula, Standard Aortic Cannula | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI) | Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease | 04/27 | 04/27 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
