Michels, Holger |
NCT05561257: Vitamin C as add-on Therapy in Patients With Acute Herpes Zoster |
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| Terminated | 2 | 12 | Europe | Vitamin C | Pascoe Pharmazeutische Praeparate GmbH | Neuropathic Pain | 02/24 | 02/24 | | |
NCT02422901: A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency |
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| Recruiting | N/A | 5000 | Europe | vitamin C, Pascorbin® 7.5g | Pascoe Pharmazeutische Praeparate GmbH | Vitamin C Deficiency, Acute Disease, Chronic Disease | 11/22 | 12/23 | | |
Steffen, Björn |
| Recruiting | 2 | 146 | Europe | Venetoclax plus Azacitidine, standard of care chemotherapy plus gemtuzumab ozogamicin | Technische Universität Dresden, University Hospital Heidelberg, AbbVie | Acute Myeloid Leukemia | 09/28 | 09/28 | | |
| Active, not recruiting | 1/2 | 55 | Europe | Venetoclax Oral Tablet, Cytarabin | Technische Universität Dresden, AbbVie | Relapsed Adult AML, Refractory AML | 10/23 | 08/25 | | |
| Recruiting | 1/2 | 214 | Europe | MODULE: conventional chemotherapy (Cytarabine+Daunorubicin) in combination with midostaurin+GO, Rydapt, Mylotarg, MAGNOLIA-trial: Midostaurin associated with conventional chemotherapy (AraC+DNR)+GO, MAGNOLIA-trial: conventional chemotherapy (AraC+DNR)+GO, MAGMA-trial:GO associated with conventional chemotherapy (AraC+DNR)+Midostaurin, MAGMA-trial: conventional chemotherapy (AraC+DNR)+Midostaurin | Technische Universität Dresden, Novartis Pharmaceuticals, Pfizer | Acute Myeloid Leukemia | 04/27 | 04/28 | | |
Sebastian, Martin |
ANTELOPE, NCT05689671: Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma |
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| Recruiting | 4 | 136 | Europe | Atezolizumab, Tecentriq, Nab paclitaxel, Abraxane, Carboplatin, Pembrolizumab, Keytruda, Cisplatin, Pemetrexed | Nikolaj Frost MD, Roche Pharma AG, Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | Non-Small Cell Lung Cancer Metastatic | 10/25 | 10/26 | | |
COSTAR Lung, NCT04655976 / 2020-003433-37: Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy |
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| Active, not recruiting | 3 | 758 | Europe, Canada, Japan, US, RoW | Cobolimab, Dostarlimab, Docetaxel | GlaxoSmithKline | Lung Cancer, Non-Small Cell | 04/25 | 10/25 | | |
| Terminated | 2a | 61 | Europe, US, RoW | DRP-104, atezolizumab | Dracen Pharmaceuticals, Inc., Dracen Pharmaceuticals, Inc. | Advanced Solid Tumor, Non Small Cell Lung Cancer Metastatic | 03/23 | 03/23 | | |
| Active, not recruiting | 1/2 | 73 | Europe | PDC*lung01, Keytruda Injectable Product, Pembrolizumab, Alimta Injectable Product, Pemetrexed | PDC*line Pharma SAS | Non Small Cell Lung Cancer | 07/24 | 12/25 | | |
PYNNACLE, NCT04585750: The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation |
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| Recruiting | 1/2 | 230 | Europe, US, RoW | PC14586, rezatapopt, pembrolizumab, KEYTRUDA®, MK-3475, KEYNOTE-D79, MK-3475-D79 | PMV Pharmaceuticals, Inc, Merck Sharp & Dohme LLC | Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor, Lung Cancer, Ovarian Cancer, Endometrial Cancer, Prostate Cancer, Colorectal Cancer, Breast Cancer, Other Cancer, Locally Advanced, Head and Neck Cancer | 03/26 | 07/26 | | |
Pinter, Andreas |
ADorable-1, NCT05559359: A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis |
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| Recruiting | 3 | 360 | Europe, Canada, Japan, US, RoW | Lebrikizumab, LY3650150, DRM06, Placebo, Topical Corticosteroid (TCS) | Eli Lilly and Company, Dermira, Inc. | Atopic Dermatitis, Eczema | 02/26 | 02/27 | | |
BRAVE-AA-PEDS, NCT05723198: A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata |
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| Recruiting | 3 | 595 | Europe, Canada, Japan, US, RoW | Baricitinib, LY3009104, Placebo | Eli Lilly and Company | Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases, Skin Diseases, Pathological Conditions, Anatomical | 09/24 | 08/29 | | |
ADorable-2, NCT05735483: A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis |
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| Enrolling by invitation | 3 | 310 | Europe, Canada, Japan, US, RoW | Lebrikizumab, LY3650150, Placebo | Eli Lilly and Company | Atopic Dermatitis, Eczema | 06/26 | 06/26 | | |
NCT05561257: Vitamin C as add-on Therapy in Patients With Acute Herpes Zoster |
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| Terminated | 2 | 12 | Europe | Vitamin C | Pascoe Pharmazeutische Praeparate GmbH | Neuropathic Pain | 02/24 | 02/24 | | |
NCT06046729: A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa |
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| Recruiting | 2 | 350 | Europe, Canada, US, RoW | Eltrekibart, LY3041658, Placebo | Eli Lilly and Company | Hidradenitis Suppurativa | 08/25 | 07/26 | | |
OREA, NCT05131373: Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris |
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| Completed | 1 | 38 | Europe | ORG101 - Experimental 1, ORG101PL - Placebo 1 | Sanofi Pasteur, a Sanofi Company | Acne Vulgaris, Acne | 11/23 | 11/23 | | |
NCT04944862: A Study of CDX-0159 in Patients With Prurigo Nodularis |
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| Completed | 1 | 24 | Europe, US | CDX-0159, barzolvolimab, Normal saline | Celldex Therapeutics | Prurigo Nodularis | 07/23 | 07/23 | | |
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Stratmann, Jan Alexander |
ANTELOPE, NCT05689671: Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma |
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| Recruiting | 4 | 136 | Europe | Atezolizumab, Tecentriq, Nab paclitaxel, Abraxane, Carboplatin, Pembrolizumab, Keytruda, Cisplatin, Pemetrexed | Nikolaj Frost MD, Roche Pharma AG, Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | Non-Small Cell Lung Cancer Metastatic | 10/25 | 10/26 | | |
| Active, not recruiting | 2 | 67 | Europe | Atezolizumab | Technische Universität Dresden, Roche Pharma AG | Large Cell Neuroendocrine Carcinoma of the Lung | 01/28 | 01/29 | | |
Pinter, Andraes |
NCT05561257: Vitamin C as add-on Therapy in Patients With Acute Herpes Zoster |
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| Terminated | 2 | 12 | Europe | Vitamin C | Pascoe Pharmazeutische Praeparate GmbH | Neuropathic Pain | 02/24 | 02/24 | | |
Chen, Tung-Te |
LANDSCAPE, NCT04943796: A Study to Learn About the Occurrence of ADHD in Adults With Mental Conditions and Their Quality of Life |
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| Active, not recruiting | N/A | 224 | Europe, Canada | | Takeda | Attention Deficit Hyperactivity Disorder (ADHD) | 11/25 | 11/25 | | |