Washington University in St. Louis / St. Louis Children's Hospital
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 3 Trials 
36 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Newland, Jason G
NCT04180462: Increasing Optimal Use of HPV Vaccination in Primary Care

Completed
N/A
20
US
Practice Facilitation, Education, Audit and Feedback, Communication Strategy
Washington University School of Medicine, National Cancer Institute (NCI)
Human Papillomavirus Vaccines
02/23
04/24
NCT04565509: Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic

Completed
N/A
3000
US
General Communication Message, Focused/Targeted Message, Best Message Alone, Best Message + Augmented Message or Implementation Strategy
Washington University School of Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Covid19, Intellectual Disability, Developmental Disability, Child Development Disorder
03/24
03/24
NCT04875520: Assessing Testing Strategies for Safe Return to K-12 Schools in an Underserved Population

Completed
N/A
2474
US
Screening testing strategy, No screening testing strategy
Washington University School of Medicine
Covid19
05/23
12/23
OPerAtiC, NCT04366440: De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

Completed
N/A
39363
US
Order set review and modification with facilitation, Order set review and modification
Washington University School of Medicine, Agency for Healthcare Research and Quality (AHRQ)
Surgical Site Infection
02/24
11/24
REVAMP, NCT05975671: Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

Recruiting
N/A
52500
US
Multifaceted de-implementation strategy to reduce vancomycin overuse, Mixed methods intervention
Children's Hospital of Philadelphia, Children's Healthcare of Atlanta, St. Louis Children's Hospital, Johns Hopkins University, University of Pennsylvania, Centers for Disease Control and Prevention
Sepsis, Sepsis Mrsa, Sepsis Bacteremia, Antimicrobial - Induced Nephropathy, Sepsis, Severe, Septic Shock, Septic Syndrome
08/25
01/26
RELAX, NCT05608993: Reducing Length of Antibiotics for Children With Ear Infections

Not yet recruiting
N/A
500
NA
High Intensity Intervention, Low Intensity Intervention
Denver Health and Hospital Authority, Agency for Healthcare Research and Quality (AHRQ), Vanderbilt University Medical Center, Washington University School of Medicine
Acute Otitis Media, Pediatric Infectious Disease, Ear Infection
04/27
10/27
Lu, Esther
NCT04966481: Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

Recruiting
3
81
US
Palbociclib, Ibrance, Cetuximab, Erbitux
Washington University School of Medicine, Pfizer, The Joseph Sanchez Foundation
HPV-unrelated Head and Neck Squamous Cell Carcinoma
02/27
02/27
NCT04412629: Cabozantinib in High Grade Neuroendocrine Neoplasms

Recruiting
2
32
US
Cabozantinib, Cabometyx, Blood for plasma biomarkers, Tissue biopsy
Washington University School of Medicine, Exelixis
High Grade Neuroendocrine Neoplasms
07/25
03/26
NCT04831320: Nab-Paclitaxel in Combination With Nivolumab to Treat Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma That Progressed on a PD-1 or PD-L1 Inhibitor

Active, not recruiting
2
46
US
nab-paclitaxel, Abraxane, Nivolumab, Opdivo
Washington University School of Medicine, Bristol-Myers Squibb
Metastatic Head-and-neck Squamous-cell Carcinoma
12/25
09/26
MINT-2, NCT06702033: The Minimalist Trial-2

Not yet recruiting
2
153
US
Radiation therapy, Cisplatin, Surgery
Washington University School of Medicine, The Joseph Sanchez Foundation
HPV-Related Oropharynx Squamous Cell Carcinoma
01/30
04/33
NCT05251233: Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy

Terminated
2
56
US
Placebo, Pantoprazole
Washington University School of Medicine
Pancreatic Cancer, Pancreas Cancer, Ampullary Cancer, Pancreas Neuroendocrine Tumor, Pancreatitis, Distal Extrahepatic Cholangiocarcinoma, Duodenal Cancer
06/24
06/24
NCT04852328: Three Schedules of CUE-101 Administered Before Surgery or Definitive Chemoradiation Therapy in HLA-A*0201 Positive Patients With Locally Advanced, HPV16-Positive Oropharyngeal Squamous-Cell Carcinoma

Recruiting
2
30
US
CUE-101
Washington University School of Medicine, Cue Biopharma
Oropharyngeal Squamous Cell Carcinoma
10/27
10/27
NCT04643379: Olaparib in Combination With Pembrolizumab and Carboplatin as First-Line Treatment of Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma

Active, not recruiting
2
30
US
Olaparib, Lynparza, Pembrolizumab, Keytruda, Carboplatin, Peripheral blood draw
Washington University School of Medicine, Merck Sharp & Dohme LLC, Joseph Sanchez Foundation
Recurrent Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Squamous Cell Carcinoma
11/25
11/26
NCT04331041: Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma

Recruiting
2
42
US
Adaptive stereotactic body radiation therapy, Adaptive SBRT, Defactinib, VS-6063, PF-04554878, Tumor biopsy, Research blood draw
Washington University School of Medicine, National Cancer Institute (NCI), Verastem, Inc.
Pancreas Cancer, Cancer of the Pancreas, Pancreas Adenocarcinoma
06/27
06/28
Rambro2, NCT05980000: Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma

Recruiting
2
72
US
Ramucirumab, Cyramza, Pembrolizumab, MK-3475, Keytruda
Washington University School of Medicine, Eli Lilly and Company
Recurrent Head and Neck Cancer, Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Carcinoma, Metastatic Head-and-neck Squamous-cell Carcinoma, Metastatic Head and Neck Cancer, HNSCC
04/28
04/31
NCT05903131: A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia

Recruiting
2
96
US
Telemedicine behavioral weight intervention, Progestin, Enhanced usual care, Levonorgestrel-releasing IUD.
Washington University School of Medicine, National Cancer Institute (NCI)
Endometrial Hyperplasia, Grade 1 Endometrial Cancer
10/28
10/29
NCT05829460: Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia

Not yet recruiting
2
96
US
Semaglutide, Placebo, LNG-IUD (Progestin), Telemedicine behavioral weight program
Washington University School of Medicine, Novo Nordisk A/S
Endometrial Hyperplasia
12/29
12/31
NCT05521997: Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer

Not yet recruiting
2
42
US
Telaglenastat, CB-893, Radiation treatment, Cisplatin
Washington University School of Medicine, National Cancer Institute (NCI), Calithera Biosciences, Inc
Advanced Cervical Carcinoma, Cervical Cancer, Cervix Cancer, Cancer of the Cervix
04/31
04/31
NCT06529809: Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer

Recruiting
1/2
50
US
Hypofractionated external beam radiation, Chemotherapy, Image-guided brachytherapy
Washington University School of Medicine
Locally Advanced Cervical Carcinoma
12/31
12/31
NCT05616624: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Recruiting
1/2
114
US
ADI-PEG 20, PEGylated arginine deiminase, Gemcitabine, Gemzar, Docetaxel, Taxotere
Washington University School of Medicine, Polaris Group
Non Small Cell Lung Cancer, Non-small Cell Lung Cancer, Small-cell Lung Cancer, Small Cell Lung Carcinoma
12/27
12/32
NCT03516708: Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

Hourglass Jan 2019 - Jan 2019 : P1/2 trial in advanced rectal cancer
Recruiting
1/2
49
US
Epacadostat, INCB024360, Short-course radiation therapy, SCRT, CAPOX chemotherapy, FOLFOX chemotherapy
Washington University School of Medicine, Incyte Corporation, National Cancer Institute (NCI)
Rectal Cancer
07/27
08/30
NCT04624113: Tazemetostat and Pembrolizumab in Patients With Pembrolizumab- or Nivolumab-Resistant, Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma

Terminated
1
13
US
Tazemetostat, Tazverik, Pembrolizumab, Keytruda
Washington University School of Medicine, Epizyme, Inc.
Head and Neck Squamous Cell Carcinoma
08/22
02/24
NCT06648434: MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Not yet recruiting
1
51
US
Zunsemetinib, ATI-450, mFOLFIRINOX
Washington University School of Medicine, National Cancer Institute (NCI), Aclaris Therapeutics, Inc.
Metastatic Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer, Cancer of the Pancreas
04/27
03/30
NCT06795009: Zanzalintinib in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

Not yet recruiting
1
36
US
Zanzalintinib, XL092, Paclitaxel, Taxol
Washington University School of Medicine, National Cancer Institute (NCI), Exelixis
Uterine Cancer, Endometrial Cancer
06/29
11/34
NCT05678348: Pyrimethamine as an Inhibitor of NRF2 in HPV-unrelated Locally Advanced Head and Neck Squamous Cell Carcinoma

Recruiting
1
21
US
Pyrimethamine, Daraprim
Washington University School of Medicine, Tilde Sciences
Head and Neck Cancer, Cancer of the Head and Neck
04/26
04/26
NCT05826015: AVB-500 (Batiraxcept) in Combination With Paclitaxel in Recurrent High Grade Uterine Cancer

Withdrawn
1
36
NA
Paclitaxel, Taxol, Batiraxcept, AVB-500
Washington University School of Medicine, National Cancer Institute (NCI), Aravive, Inc.
Recurrent High Grade Uterine Cancer
06/29
06/34
NCT04508764: Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome

Terminated
N/A
96
US
Families Accelerating Cascade Testing Toolkit, FACTT
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Hereditary Breast and Ovarian Cancer, Lynch Syndrome
03/24
03/24
NCT05179837: Endoscopic Optical Coherence Tomography for Screening and Diagnosis of Colorectal Precancerous and Malignant Polyps

Active, not recruiting
N/A
36
US
Optical coherence tomography probe, OCT probe
Washington University School of Medicine
Colon Cancer, Rectal Cancer, Cancer of the Rectum, Cancer of the Colon, Precancerous Polyp, Malignant Polyp
04/23
12/24
NCT04651504: Rural Colon Cancer Screening Toolkit Intervention

Recruiting
N/A
83663
US
Colorectal Cancer Toolkit
Washington University School of Medicine, National Institutes of Health (NIH), National Cancer Institute (NCI)
Colon Cancer Screening
07/25
07/25
NCT05762757: Patient-centered Educational Material to Improve Colposcopy Adherence

Completed
N/A
25
US
Colposcopy educational material
Washington University School of Medicine, American Association of Obstetricians and Gynecologists
Cervical Cancer Screening
09/24
09/24
NOM-ERA, NCT03904043: Non-Operative Management and Early Response Assessment in Rectal Cancer

Active, not recruiting
N/A
63
US
Radiation therapy, FOLFOX regimen, Functional Assessment of Cancer Therapy-Colorectal cancer (FACT-C) questionnaire, Rectal biopsy samples, Blood for ctDNA
Washington University School of Medicine
Adenocarcinoma of the Lower Rectum
08/24
04/26
BASICS, NCT05458960: Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate

Not yet recruiting
N/A
81
US
Social needs navigator program, Enhanced usual care
Washington University School of Medicine, National Center for Advancing Translational Sciences (NCATS)
Cervical Cancer
07/26
11/26
SORT, NCT05183932: Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer

Recruiting
N/A
440
Canada, US
Washington University School of Medicine, National Cancer Institute (NCI)
Non Small Cell Lung Cancer, Non-small Cell Lung Cancer
01/27
01/27
MOTIVATE, NCT05846841: Personalized Tobacco Treatment in Primary Care

Recruiting
N/A
850
US
Precision Treatment, Usual Care
Washington University School of Medicine, National Institute on Drug Abuse (NIDA), National Cancer Institute (NCI)
Physician's Role, Smoking Cessation, Smoking
03/28
09/28
NCT04178018: Transvaginal Ultrasound and Photoacoustic Imaging of Ovary

Recruiting
N/A
310
US
Photoacoustic imaging, PAI, Photoacoustic tomography, Ultrasound
Washington University School of Medicine, National Cancer Institute (NCI)
Ovary; Anomaly
01/27
01/27
METEOR-CRATR, NCT05975593: MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial

Recruiting
N/A
60
US
Tumor collection via biopsy, Blood collection, Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI), DBSI MRI
Washington University School of Medicine, National Cancer Institute (NCI)
Locally Advanced Cervical Carcinoma, Locally Advanced Cervical Cancer, Locally Advanced Pancreas Cancer, Locally Advanced Pancreatic Carcinoma, Locally Advanced Pancreatic Cancer, Cervical Cancer, Pancreas Cancer, Pancreatic Cancer, Cancer of the Cervix, Cancer of the Pancreas
12/32
12/32
McKay, Virginia
No trials found

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