| Recruiting | 3 | 250 | Europe, US, RoW | ZYN002 - transdermal gel, cannabidiol formulated as a clear gel that can be applied to the skin (transdermal delivery), Placebo, Placebo Comparator, Matching Placebo | Zynerba Pharmaceuticals, Inc., Zynerba Pharmaceuticals, Inc. | Fragile X Syndrome | 05/25 | 05/25 | | |
NCT03479476: A Trial of Metformin in Individuals With Fragile X Syndrome |
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| Completed | 2/3 | 120 | Canada, US | Placebo Medication, Placebo, Metformin, Glumetza, Glucophage, Fortamet, Riomet | University of California, Davis, University of Alberta, St. Justine's Hospital | Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders | 05/24 | 05/24 | | |
NCT05233579: Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS |
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| Completed | N/A | 15 | US | Sulforaphane, Avmacol | University of California, Davis | Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis) | 01/23 | 01/23 | | |
