| Bourdin, Arnaud |
| Recruiting | 4 | 72 | Europe | Azithropycin according to symptoms, Azithromycin according to rheology or symptoms | University Hospital, Montpellier, Rheonova | Chronic Obstructive Pulmonary Disease | 02/26 | 02/26 | | |
SECURE, NCT05626777: Symptoms Control and adhErenCe Assessment During Treatment With MepolizUmab New pREfilled Devices |
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| Active, not recruiting | 4 | 20 | Europe | Pre-filled syringe, mepolizumab 100 mg/month, Auto-injector pen, mepolizumab 100 mg/month | Hospices Civils de Lyon, GlaxoSmithKline | Asthma | 03/26 | 07/26 | | |
| Recruiting | 4 | 220 | Europe | Benralizumab Prefilled Syringe, Transcriptomic | Nantes University Hospital, AstraZeneca, Ministère de la Santé - France | Asthma; Eosinophilic, Severe Asthma | 10/26 | 11/26 | | |
| Terminated | 3 | 372 | Europe, US, RoW | Pamrevlumab, FG-3019, Placebo | FibroGen | Idiopathic Pulmonary Fibrosis | 09/23 | 09/23 | | |
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| Completed | 3 | 806 | Europe, Canada, US, RoW | Placebo, Mepolizumab | GlaxoSmithKline, PPD DEVELOPMENT, LP | Pulmonary Disease, Chronic Obstructive | 08/24 | 08/24 | | |
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| Recruiting | 3 | 600 | Europe | 5 days of systemic corticotherapy (prednisone), 5 days of placebo | University Hospital, Montpellier | COPD Exacerbation | 10/24 | 01/25 | | |
| Recruiting | 3 | 90 | Europe | Tezepelumab, placebo | University Hospital, Montpellier | Airway Remodelling, Asthmatic | 12/25 | 06/26 | | |
| Active, not recruiting | 3 | 1667 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS) | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 10/25 | 10/25 | | |
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OCEAN, NCT05263934 / 2021-005726-15: Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) |
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| Recruiting | 3 | 160 | Europe, Canada, Japan, US, RoW | Depemokimab, Mepolizumab, Placebo matching mepolizumab, Placebo matching depemokimab | GlaxoSmithKline | Eosinophilic Granulomatosis With Polyangiitis | 10/25 | 11/25 | | |
EXAFIP2, NCT05674994: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 110 | Europe | Methylprednisone/Prednisone, Placebo | Fondation Hôpital Saint-Joseph | Acute Exacerbation of Idiopathic Pulmonary Fibrosis | 10/25 | 12/26 | | |
| Terminated | 3 | 186 | Europe, Canada, US, RoW | AV-101 | Aerovate Therapeutics, Aerovate Therapeutics Inc | Pulmonary Arterial Hypertension | 08/24 | 08/24 | | |
| Terminated | 2/3 | 202 | Europe, Canada, US, RoW | AV-101, Placebo | Aerovate Therapeutics, Aerovate Therapeutics, Inc. | Pulmonary Arterial Hypertension | 08/24 | 08/24 | | |
| Withdrawn | 2b | 250 | Europe | DILTIAZEM TEVA 60 mg or placebo | Hospices Civils de Lyon, Signia Therapeutics | COVID-19 | 10/24 | 12/24 | | |
| Completed | N/A | 11 | Europe | Bronchial biopsy, Skin biopsy, Blood sample | University Hospital, Montpellier | Pulmonary Disease, Chronic Obstructive, Smoking | 03/22 | 03/22 | | |
EXPOSOMFPI, NCT04619199: Influence of Socioeconomic and Environmental Factors on the Natural History of Idiopathic Pulmonary Fibrosis |
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| Recruiting | N/A | 200 | Europe | Blood sample | Assistance Publique - Hôpitaux de Paris, Institut National de la Santé Et de la Recherche Médicale, France | Idiopathic Pulmonary Fibrosis, Pulmonary Disease, Pulmonary Medicine | 04/22 | 04/25 | | |
NCT04517916: Zephyr Etude Post-Inscription (French Registry) |
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| Active, not recruiting | N/A | 155 | Europe | Zephyr Valve, Zephyr System, BLVR | Pulmonx Corporation | Emphysema or COPD | 06/22 | 09/25 | | |
HeartSoar, NCT03770390: Cardiorespiratory Assessment and Quality of Life After Surgical Correction of Congenital Wall Malformations |
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| Recruiting | N/A | 70 | Europe | Surgical correction of pectus excavatum | University Hospital, Montpellier | Funnel Chest | 12/23 | 12/24 | | |
NCT05728749: A Multicentre, Prospective, Non-interventional Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extra-fine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Outcomes |
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| Recruiting | N/A | 300 | Europe | Non-interventional | Chiesi SAS, Gesellschaft für Therapieforschung mbH | ASTHMA | 03/24 | 03/25 | | |
| Recruiting | N/A | 160 | Europe | Predictive data, Lung resection | University Hospital, Montpellier | Non-small Cell Lung Cancer | 09/25 | 09/26 | | |
AsthmaTrain, NCT05248126: Standard Patient Training Versus Vik Chatbot Guided Training: a Randomized Controlled Trial for Asthma Patients |
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| Completed | N/A | 73 | Europe | Standard patient education, Chatbot patient education | University Hospital, Montpellier | Asthma | 10/23 | 10/23 | | |
| Completed | N/A | 49 | Europe | Rehabilitation, Supervised rehabilitation | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Pulmonary Arterial Hypertension | 12/22 | 01/24 | | |
| Recruiting | N/A | 70 | Europe | Pedometer, 6 minute walking test | University Hospital, Montpellier | Hypertension, Pulmonary | 06/24 | 06/24 | | |
| Active, not recruiting | N/A | 464 | Europe, US | Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care | Nuvaira, Inc. | COPD | 10/24 | 09/28 | | |
| Didier, Alain |
| Recruiting | 4 | 72 | Europe | Azithropycin according to symptoms, Azithromycin according to rheology or symptoms | University Hospital, Montpellier, Rheonova | Chronic Obstructive Pulmonary Disease | 02/26 | 02/26 | | |
| Recruiting | 4 | 220 | Europe | Benralizumab Prefilled Syringe, Transcriptomic | Nantes University Hospital, AstraZeneca, Ministère de la Santé - France | Asthma; Eosinophilic, Severe Asthma | 10/26 | 11/26 | | |
| Recruiting | 3 | 90 | Europe | Tezepelumab, placebo | University Hospital, Montpellier | Airway Remodelling, Asthmatic | 12/25 | 06/26 | | |
| Withdrawn | 2b | 250 | Europe | DILTIAZEM TEVA 60 mg or placebo | Hospices Civils de Lyon, Signia Therapeutics | COVID-19 | 10/24 | 12/24 | | |
NCT04438408: National Survey on Care Pathway and Quality of Life in Patients With Severe Asthma According to Their Phenotype. |
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| Recruiting | N/A | 400 | Europe | questionaires | University Hospital, Toulouse, AstraZeneca | Asthma Chronic, Severe Asthma | 09/21 | 12/21 | | |
| Recruiting | N/A | 144 | Europe | Strategy with thoracic ultrasound | University Hospital, Toulouse | Pleural Effusion | 12/21 | 12/22 | | |
| Terminated | N/A | 7 | Europe | Cough assessment, Neurological tests and cardiovascular tests, Skin biopsy | University Hospital, Toulouse | Chronic Cough, Type 2 Diabetes | 12/22 | 12/22 | | |
OPPAÃŽ, NCT03527992: Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia |
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| Recruiting | N/A | 128 | Europe | O2 automated, O2 standard | University Hospital, Toulouse | Pneumonia, Pneumonia, Ventilator-Associated, Length of Stay | 10/28 | 10/28 | | |
| Guilleminault, Laurent |
| Recruiting | 4 | 72 | Europe | Azithropycin according to symptoms, Azithromycin according to rheology or symptoms | University Hospital, Montpellier, Rheonova | Chronic Obstructive Pulmonary Disease | 02/26 | 02/26 | | |
SECURE, NCT05626777: Symptoms Control and adhErenCe Assessment During Treatment With MepolizUmab New pREfilled Devices |
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| Active, not recruiting | 4 | 20 | Europe | Pre-filled syringe, mepolizumab 100 mg/month, Auto-injector pen, mepolizumab 100 mg/month | Hospices Civils de Lyon, GlaxoSmithKline | Asthma | 03/26 | 07/26 | | |
| Recruiting | 4 | 220 | Europe | Benralizumab Prefilled Syringe, Transcriptomic | Nantes University Hospital, AstraZeneca, Ministère de la Santé - France | Asthma; Eosinophilic, Severe Asthma | 10/26 | 11/26 | | |
| Completed | 3 | 445 | Europe, RoW | 5-grass mix SLIT-drops, SLIToneULTRA, Placebo | ALK-Abelló A/S, Syneos Health | Allergy | 09/23 | 09/23 | | |
| Recruiting | 3 | 90 | Europe | Tezepelumab, placebo | University Hospital, Montpellier | Airway Remodelling, Asthmatic | 12/25 | 06/26 | | |
| Active, not recruiting | 3 | 1667 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS) | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 10/25 | 10/25 | | |
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NCT04438408: National Survey on Care Pathway and Quality of Life in Patients With Severe Asthma According to Their Phenotype. |
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| Recruiting | N/A | 400 | Europe | questionaires | University Hospital, Toulouse, AstraZeneca | Asthma Chronic, Severe Asthma | 09/21 | 12/21 | | |
NCT04384835: Analysis of Sexual Bias in Type 2 Innate Lymphoid Cells (ILC2) in Asthmatic Patients |
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| Completed | N/A | 34 | Europe | Blood sample collection (one tube), Blood sample collection (five tubes) | University Hospital, Toulouse | Asthma | 05/22 | 04/23 | | |
| Terminated | N/A | 7 | Europe | Cough assessment, Neurological tests and cardiovascular tests, Skin biopsy | University Hospital, Toulouse | Chronic Cough, Type 2 Diabetes | 12/22 | 12/22 | | |
| Recruiting | N/A | 1376 | Europe | collection of blood and urine | University Hospital, Toulouse | Allergy and Immunology | 01/25 | 01/26 | | |
MyCADO, NCT05789927: Environmental Mycobiota: In-depth Characterisation and Determinants Involved in Asthma Emission |
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| Recruiting | N/A | 80 | Europe | Assessment of the microbial exposome | University Hospital, Bordeaux, University of Bordeaux | Asthma | 04/25 | 04/25 | | |
| Active, not recruiting | N/A | 576 | Europe | questionnaires | University Hospital, Toulouse, MSD France | Refractory Chronic Cough | 06/25 | 06/26 | | |
| Recruiting | N/A | 3000 | Europe | | University Hospital, Strasbourg, France | Hypersensitivity, Drug | 05/31 | 05/31 | | |
BIRD-A, NCT06037967: Biobanking for Biomarkers In Respiratory Disease, Allergic Diseases and/or Mast Cell Disorders |
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| Recruiting | N/A | 3200 | Europe | | University Hospital, Toulouse | Allergic Diseases, Asthma, Mast Cell Disorders | 05/38 | 06/38 | | |
| Guibert, Nicolas |
| Recruiting | 4 | 72 | Europe | Azithropycin according to symptoms, Azithromycin according to rheology or symptoms | University Hospital, Montpellier, Rheonova | Chronic Obstructive Pulmonary Disease | 02/26 | 02/26 | | |
| Completed | N/A | 216 | Europe | blood sample collection for CTC and MDSC analysis | University Hospital, Toulouse | Lung Cancer | 10/21 | 12/21 | | |
NCT04517916: Zephyr Etude Post-Inscription (French Registry) |
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| Active, not recruiting | N/A | 155 | Europe | Zephyr Valve, Zephyr System, BLVR | Pulmonx Corporation | Emphysema or COPD | 06/22 | 09/25 | | |
| Completed | N/A | 102 | Europe, RoW | AeriSeal, Zephyr Valves, Bronchoscopic Lung Volume Reduction (BLVR), Zephyr System | Pulmonx Corporation | Emphysema, COPD, Severe Emphysema | 10/23 | 10/24 | | |
NCT06035120: An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients with Severe Emphysema |
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| Recruiting | N/A | 200 | Europe, US, RoW | AeriSeal System | Pulmonx Corporation | Emphysema, Pulmonary, Emphysema or COPD | 06/27 | 03/28 | | |
TATUM, NCT04848025: Treatment of Central Airway Stenoses Using Computer-Assisted Customized 3d Stents |
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| Recruiting | N/A | 30 | Europe | Custom-designed tracheobronchial prostheses | University Hospital, Toulouse | Airway Disease | 12/25 | 12/25 | | |
REPEAT, NCT06181357: Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction with Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction with One-stage ZEPHYR® Valves |
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| Recruiting | N/A | 244 | Europe | Endoscopic lung volume reduction in 2 stages, Endoscopic lung volume reduction in 1 stage | University Hospital, Limoges | COPD | 06/27 | 06/27 | | |
| Active, not recruiting | N/A | 464 | Europe, US | Targeted Lung Denervation (TLD), TLD, TLD Therapy, Optimal Medical Care | Nuvaira, Inc. | COPD | 10/24 | 09/28 | | |
AERATE, NCT04719845: DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis |
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| Recruiting | N/A | 108 | Europe, Canada | Endoscopic laser resection, Dilatation | Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec | Tracheal Stenosis | 03/25 | 03/25 | | |
| Not yet recruiting | N/A | 150 | NA | Treatment plus Optimal Medical Therapy, InterVapor, BTVA, Optimal Medical Therapy | Uptake Medical Technology, Inc., MedPass International | Emphysema | 07/25 | 07/26 | | |
LUNG-RESIST, NCT04222335: Understanding and Overcoming the Early Adaptive Resistance to EGFR Tyrosine-kinase Inhibitors in Lung Cancer Patients |
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| Recruiting | N/A | 80 | Europe | Blood samples | University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France, National Cancer Institute, France | Lung Cancer, Nonsmall Cell | 12/28 | 12/28 | | |
BIRD-NK, NCT06054854: Biobank for the Identification of Biomarkers in Lung Cancer (BIRD, Biomarkers in Respiratory Disease) |
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| Not yet recruiting | N/A | 3000 | Europe | Extra blood sampling, Non-invasive or leftover samples or medical waste | University Hospital, Toulouse | Lung Nodule, Lung Cancer | 10/33 | 10/33 | | |
| Not yet recruiting | N/A | 50 | Europe | Molecular analysis of surnatant | University Hospital, Toulouse | Lung Cancer | 12/22 | 12/22 | | |
| Marchandise, Sandrine Pontier |
| Recruiting | 4 | 72 | Europe | Azithropycin according to symptoms, Azithromycin according to rheology or symptoms | University Hospital, Montpellier, Rheonova | Chronic Obstructive Pulmonary Disease | 02/26 | 02/26 | | |
| Brouquieres, Danielle |
| Recruiting | 4 | 72 | Europe | Azithropycin according to symptoms, Azithromycin according to rheology or symptoms | University Hospital, Montpellier, Rheonova | Chronic Obstructive Pulmonary Disease | 02/26 | 02/26 | | |
