| Li, Yan |
NCT04035824: Gastrodia and Uncaria Recipe in Treating Stage-one Hypertension: an Evidence-based Optimization Study |
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| Completed | 4 | 605 | RoW | Gastrodia and Uncaria granule, Placebo of Gastrodia and Uncaria granule | Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | Hypertension | 04/24 | 04/24 | | |
NCT05089448: Morning Versus Bedtime Dosing of Antihypertensive Medication |
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| Recruiting | 4 | 300 | RoW | Alisartan, Amlodipine besylate | Yan Li | Hypertension, Blood Pressure, Drug Use | 06/26 | 09/26 | | |
NCT03825692: International Clinical Study of Zhizhu Kuanzhong Capsule |
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| Recruiting | 4 | 480 | RoW | Zhizhu Kuanzhong Capsule, ZZKZ capsule, Zhizhu Kuanzhong Placebo Capsule, placebo | Xiyuan Hospital of China Academy of Chinese Medical Sciences | Functional Dyspepsia, Postprandial Distress Syndrome | 12/23 | 12/23 | | |
| Completed | 3 | 1328 | Europe, Canada, Japan, US, RoW | Mirikizumab SC, LY3074828, Mirikizumab IV, Placebo SC | Eli Lilly and Company | Ulcerative Colitis | 11/21 | 02/25 | | |
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NCT04078568: Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease |
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| Completed | 3 | 3208 | RoW | IVIG, Intravenous Immunoglobulins, Human, Aspirin, Acetylsalicylic acid, Prednisolone, STEROLONE | Children's Hospital of Fudan University, Jiangxi Province Children's Hospital, First People's Hospital of Hangzhou, Shengjing Hospital, The First Hospital of Jilin University, Chengdu Women's and Children's Central Hospital, Children's Hospital of Chongqing Medical University, Inner Mongolia People's Hospital, Sichuan Provincial People's Hospital, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Third Affiliated Hospital of Zhengzhou University, Children's Hospital of Soochow University, Yuying Children's Hospital of Wenzhou Medical University, Beijing Children's Hospital, Qilu Hospital of Shandong University | Kawasaki Disease | 12/24 | 11/25 | | |
| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc., Chinook Therapeutics U.S., Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
NCT05433480: A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer |
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| Active, not recruiting | 3 | 274 | RoW | BPI-16350, placebo, Fulvestrant | Betta Pharmaceuticals Co., Ltd. | Breast Cancer | 12/23 | 07/25 | | |
nAMD, NCT05461339: TAB014 Compared to Lucentis® in Patients with Neovascular Age-related Macular Degeneration |
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| Active, not recruiting | 3 | 488 | RoW | TAB014 Monoclonal Antibody Injection, TAB014, Ranibizumab Injection [Lucentis], Lucentis | TOT Biopharm Co., Ltd., Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Neovascular Age-related Macular Degeneration | 09/24 | 02/25 | | |
NCT06292013: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) |
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| Active, not recruiting | 3 | 17300 | Europe, Canada, Japan, US, RoW | Lepodisiran Sodium, LY3819469, Placebo | Eli Lilly and Company | Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a) | 03/29 | 03/29 | | |
| Completed | 3 | 928 | Europe, Canada, Japan, US, RoW | Insulin Efsitora Alfa, LY3209590 and Basal Insulin-FC, Insulin Degludec | Eli Lilly and Company, Eli Lilly and Company | Diabetes, Type 2 Diabetes | 04/24 | 04/24 | | |
NCT06387069: A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia |
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| Recruiting | 3 | 316 | RoW | HMPL-306 Regimen, Salvage Chemotherapy Regimen | Hutchmed | Acute Myeloid Leukemia | 12/28 | 09/29 | | |
TRAPP, NCT05811676: Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Pregnant Women With Placenta Previa |
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| Completed | 3 | 1732 | RoW | Tranexamic acid, 0.9% sodium chloride | Guangzhou Medical University, Dongguan Maternal and Child Health Care Hospital, Foshan Women's and Children's Hospital, BoAi Hospital of Zhongshan, Women and Children's Hospital of Chongqing Medical University, Tianjin Central Hospital of Gynecology Obstetrics, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Urumqi Maternal and Child Health Care Hospital, Zhuhai Women and Children's Hospital, The First Affiliated Hospital of Zhengzhou University, Hunan Provincial Maternal and Child Health Care Hospital, Dalian women and children's medical group, Nanfang Hospital, Southern Medical University, Huadu District People's Hospital of Guangzhou, Northwest Women's and Children's Hospital, Xi'an, Shaanxi, First Affiliated Hospital, Sun Yat-Sen University, Shenzhen Maternity & Child Healthcare Hospital, Shenzhen Baoan Women's and Children's Hospital, Dongguan People's Hospital, First Affiliated Hospital of Xinjiang Medical University, Tongji Hospital, Peking Union Medical College, Second Affiliated Hospital of Guangzhou Medical University, Fifth Affiliated Hospital of Guangzhou Medical University, Shijiazhuang Obstetrics and Gynecology Hospital | Hemorrhage, Postpartum, Placenta Previa | 02/25 | 03/25 | | |
RECAST-MT, NCT06559241: Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy（） |
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| Recruiting | 3 | 2105 | RoW | 14-day remote ischemic conditioning, 14-day RIC, 30-day remote ischemic conditioning, 30-day RIC, Endovascular thrombectomy, EVT, Best medical management | Capital Medical University | Acute Ischemic Stroke, Anterior Circulation Brain Infarction | 11/26 | 02/27 | | |
NCT04578613: ICP-022 Versus Chlorambucil Combined With Rituximab in the Treatment of Untreated CLL/SLL |
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| Recruiting | 3 | 218 | RoW | ICP-022, Chlorambucil, Rituximab | Beijing InnoCare Pharma Tech Co., Ltd. | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | 12/24 | 06/25 | | |
NCT06900920: A Study of TQB3473 Tablets Compared to Placebo in the Treatment of Adult Primary Immune Thrombocytopenia |
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| Recruiting | 3 | 199 | RoW | TQB3473 Tablets, TQB3473 Placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Primary Immune Thrombocytopenia | 03/27 | 12/27 | | |
NCT07187960: Evaluation of the Efficacy and Safety of TQB2825 Injection Compared to Immunotherapy in the Treatment of Recurrent/Refractory Follicular Lymphoma |
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| Not yet recruiting | 3 | 228 | RoW | TQB2825 Injection, Rituximab Injection | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | Follicular Lymphoma | 10/28 | 02/29 | | |
| Not yet recruiting | 3 | 220 | RoW | Perirenal adipose tissue modification by focused power ultrasound, Sham | Yan Li | Resistant Hypertension | 12/28 | 06/29 | | |
NCT07569757: Clinical Study of TQB2934 Injection in Relapsed/Refractory Multiple Myeloma |
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| Not yet recruiting | 3 | 260 | RoW | TQB2934 injection, Pomalidomide Capsule, Selinexor tablets, Dexamethasone tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Multiple Myeloma | 12/28 | 12/30 | | |
| Not yet recruiting | 3 | 2832 | RoW | Finerenone, Placebo | Second Affiliated Hospital, School of Medicine, Zhejiang University | HFpEF - Heart Failure With Preserved Ejection Fraction, TAVI(Transcatheter Aortic Valve Implantation), Finerenone | 12/29 | 12/29 | | |
| Active, not recruiting | 3 | 15374 | Europe, Canada, Japan, US, RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Obesity, Overweight | 10/27 | 10/27 | | |
NCT06083623: A Trial to Evaluate the Efficacy and Safety of TNM001 for the Prevention of Lower Respiratory Tract Infection Caused by Respiratory Syncytial Virus in Infants |
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| Completed | 2/3 | 2282 | RoW | TNM001, placebo | Zhuhai Trinomab Pharmaceutical Co., Ltd. | Respiratory Syncytial Virus Infections | 06/25 | 11/25 | | |
NCT04405154: A Study of Concomitant Camrelizumab With Chemoradiation for Locally Advanced Head and Neck Cancer |
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| Not yet recruiting | 2 | 32 | NA | Camrelizumab, SHR-1210, Cisplatin, Platinol, IMRT or VMAT | West China Hospital | Head and Neck Neoplasms | 05/23 | 05/25 | | |
NCT05299697: A Study of TG103 Injection in Overweight or Obesity |
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| Recruiting | 2 | 195 | RoW | TG103 15 mg, TG103 22.5 mg, Placebo | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Overweight or Obesity | 06/23 | 09/23 | | |
NCT06206720: A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV |
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| Completed | 2 | 60 | RoW | Deuremidevir Hydrobromide for Suspension, VV116, Placebo, VV116 placebo | Vigonvita Life Sciences | Respiratory Syncytial Virus Infection | 06/25 | 06/25 | | |
NCT06481085: To Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus |
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| Completed | 2 | 324 | RoW | HDM1002 50 mg, HDM1002, HDM1002 100 mg, HDM1002 200 mg, HDM1002 400 mg, HDM1002 200 mg BID, Placebo, Matching placebo for group A to group E | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Type 2 Diabetes | 05/25 | 06/25 | | |
| Active, not recruiting | 2 | 103 | Europe, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627 | Novartis Pharmaceuticals | IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy | 07/24 | 10/26 | | |
NCT07083739: A Study on the Safety and Efficacy of TQB3473 Tablets in the Treatment of Persistent or Chronic Primary Immune Thrombocytopenia (ITP) in Adults |
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| Not yet recruiting | 2 | 320 | RoW | TQB3473 Tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Primary Immune Thrombocytopenia | 09/27 | 03/28 | | |
NCT07185776: A Study of HRS-5632 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events |
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| Active, not recruiting | 2 | 203 | RoW | HRS-5632 Injection, HRS-5632 Injection Placebo | Fujian Shengdi Pharmaceutical Co., Ltd. | Lipoprotein Disorder | 04/27 | 10/27 | | |
| Active, not recruiting | 2 | 356 | Europe, RoW | SKB264, MK-2870, Sacituzumab Tirumotecan (Sac-TMT), Pembrolizumab, MK-3475, Carboplatin, Carboplatin for injection, Osimertinib, Osimertinib Mesylate | Klus Pharma Inc., Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Advanced or Metastatic Non-small Cell Lung Cancer | 06/26 | 12/26 | | |
NCT05879055: A Study of PM8002 in Combination With Chemotherapy in Patients With NEN |
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| Recruiting | 2 | 60 | RoW | PM8002, FOLFIRI | Biotheus Inc. | Neuroendocrine Neoplasm | 01/27 | 01/28 | | |
NCT06106841: TQB3909 Tablets in Subjects With Relapsed or Refractory Mantle Cell Lymphoma (MCL) |
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| Terminated | 1/2 | 19 | RoW | 400mg of TQB3909 tablets, 600mg of TQB3909 tablets | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Mantle Cell Lymphoma | 10/24 | 10/24 | | |
| Active, not recruiting | 1/2 | 66 | RoW | BN104 monotherapy, BN104 monotherapy - rp2d | Institut de Recherches Internationales Servier (I.R.I.S.) | ALL, Adult, AML, Adult, Acute Leukaemia, KMT2A Rearrangement, NPM1 Mutation, NUP98 Gene Rearrangement, Menin Inhibitors | 12/26 | 12/27 | | |
| Recruiting | 1 | 20 | Europe | Oxaliplatin, Intraperitoneal catheter | Oslo University Hospital, Oslo University Hospital | Peritoneal Metastases, Colo-rectal Cancer | 03/23 | 06/23 | | |
| Recruiting | 1 | 76 | RoW | HS-10380, Placebo | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Schizophrenia | 06/23 | 07/23 | | |
NCT06594315: Assessing Brain Metabolism Using MRS With Deuterated Glucose |
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| Active, not recruiting | N/A | 80 | US | Deuterated Glucose, Hydrogen gas (H2) glucose, [6,6'-2H2] glucose, Magnetic Resonance Imaging (MRI), MRI, Blood Sample, MR spectroscopy (MRS), MRS | University of California, San Francisco | Glioma | 07/27 | 07/27 | | |
NCT06610604: Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules |
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| Recruiting | N/A | 500 | RoW | thermal ablation, thyroidectomy | Ming-an Yu | Thyroid Nodule | 06/27 | 12/27 | | |
NCT05258461: An Innovative Smartphone Application for Adverse Event Management During Breast Cancer Adjuvant Chemotherapy |
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| Not yet recruiting | N/A | 108 | NA | use of a smartphone app for adverse event management, conventional adverse event management | Peking Union Medical College Hospital | Breast Cancer | 10/22 | 12/22 | | |
NCT03547856: A Registry Study on the "Action of Controlling Ambulatory Blood Pressure to Target in Ten Thousand Patients" |
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| Recruiting | N/A | 10000 | RoW | | Yan Li | Hypertension, Blood Pressure, Cardiovascular Diseases | 09/26 | 12/26 | | |
ASORPWICE, NCT03521739: Association of Synchronous Four-limb blOod pRessure and Pulse Wave velocIty With Cardiovascular Events |
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| Recruiting | N/A | 100000 | RoW | | Chinese Academy of Medical Sciences, Fuwai Hospital | Blood Pressure, Pulse Wave Analysis, Ankle Brachial Index, Patient Outcome Assessment | 12/22 | 12/23 | | |
| Recruiting | N/A | 4500 | RoW | | Shanghai Institute of Hypertension | Nocturnal Hypertension | 09/26 | 12/26 | | |
PROMISE, NCT04135911: A Prospective Study on The"Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting" |
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| Suspended | N/A | 2000 | RoW | | Yan Li | Hypertension, Blood Pressure | 03/26 | 03/26 | | |
NCT05535400: Effects of Physical-Psychological Integrative Intervention on SCI Patient: a Pilot Randomized Controlled Trial |
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| Completed | N/A | 72 | RoW | Physical-Psychological Integrative Intervention, Brief online didactic education | The Hong Kong Polytechnic University | Spinal Cord Injuries, Physical Inactivity, Depression, Chronic Pain | 12/22 | 07/23 | | |
| Recruiting | N/A | 60 | US | | Oregon Health and Science University, National Eye Institute (NEI) | Fuchs Dystrophy, Pseudophakic Bullous Keratopathy | 06/27 | 06/28 | | |
NCT05558657: Effect of Acupressure on Constipation in Community-dwelling Spinal Cord Injury Patients: a Randomized Controlled Trial |
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| Completed | N/A | 80 | RoW | Home-based, acupressure combined with nursing education, Home-based, manual light touch of the abdomen combined with nursing education | The Hong Kong Polytechnic University | Spinal Cord Injuries, Traditional Chinese Medicine | 09/24 | 09/24 | | |
NCT05531058: The Impact of a Web-based Psychoeducation Programme with a Motivational AI Chatbot on Covid-19 Vaccine Hesitancy |
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| Completed | N/A | 168 | RoW | AI-driven Vaccine Communicator, Self-learning of COVID-19 vaccine knowledge | The Hong Kong Polytechnic University | Vaccine Hesitancy, COVID-19 | 06/24 | 06/24 | | |
NCT01243931: Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy |
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| Recruiting | N/A | 80 | US | OCT-guided laser phototherapeutic keratectomy, Manufacturer/Name OCT Technology 510(K), Optovue/RTVue-CAM Fourier-domain K071250, Bioptigen/Bioptigen Fourier-domain K063343, Zeiss/Visante Time-domain K051789 | Oregon Health and Science University, National Eye Institute (NEI) | Corneal Opacity | 12/26 | 12/26 | | |
NCT02109471: Observational Study of Corneal Opacities in Adults |
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| Recruiting | N/A | 150 | US | | Oregon Health and Science University, National Eye Institute (NEI) | Corneal Opacities (Scar and Stromal Dystrophy) | 12/25 | 12/25 | | |
| Recruiting | N/A | 75 | US | | Oregon Health and Science University | Uveitis | 12/25 | 12/25 | | |
NCT06306378: The Relationship Between Social Memory Disorders and Sleep Spindles in Children With Autism Spectrum Disorder |
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| Recruiting | N/A | 60 | RoW | social memory levels and spindle levels | First Affiliated Hospital Xi'an Jiaotong University, Xi'an TCM Hospital of Encephalopathy | Autism Spectrum Disorder | 03/24 | 04/24 | | |
| Recruiting | N/A | 445 | US | Optical Coherence Tomography | Oregon Health and Science University | Keratoconus, Corneal Opacity, Corneal Dystrophy | 02/30 | 02/31 | | |
| Active, not recruiting | N/A | 60 | US | SKY Breath Intervention | University of California, San Francisco | Depression, Anxiety Disorders | 04/28 | 12/28 | | |
OCT IOL, NCT00532051: Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography |
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| Recruiting | N/A | 690 | US | OCT measurements, Manufacturer/Name OCT Technology 510(K), Optovue/RTVue-CAM Fourier-domain K071250, Bioptigen/Bioptigen Fourier-domain K063343, Zeiss/Visante Time-domain K051789 | Oregon Health and Science University, National Eye Institute (NEI) | Cataract | 07/26 | 07/26 | | |
NCT06686134: Comprehensive Clinical Evaluation Study of GLP-1RA |
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| Recruiting | N/A | 492 | RoW | | LI YAN | T2DM | 12/25 | 07/26 | | |
NCT07065747: Quantification & Classification of Inflammatory Cells in Uveitis Using OCT |
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| Recruiting | N/A | 125 | US | | Oregon Health and Science University, National Eye Institute (NEI) | Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus, Juvenile Idiopathic Arthritis (JIA), Spondyloarthritis (SA), Sarcoidosis, Posterior Vitreous Detachment | 09/26 | 12/26 | | |
PERSIST Ⅲ, NCT06853470: Prospective Evaluation for Receiving SynFlow 3.0 Interventional Circulatory Support in High-risk PCI: A Randomized Controlled Trial |
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| Completed | N/A | 222 | RoW | VA-ECMO circulatory support, SynFlow 3.0 circulatory support, percutaneous coronary intervention | ForQaly Medical (Shanghai) Co., Ltd | High Risk PCI, Coronary Arterial Disease (CAD) | 05/25 | 08/25 | | |
| Completed | N/A | 482 | RoW | | Takeda | Multiple Myeloma, Neoplasms, Plasma Cell | 02/26 | 02/26 | | |
TEAS/ASD, NCT06763237: Abdominal Transcutaneous Electrical Acupoint Stimulation on Children With Autism Spectrum Disorder |
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| Not yet recruiting | N/A | 42 | RoW | abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS), TEAS, Applied Behavior Analysis (ABA) therapy | First Affiliated Hospital Xi'an Jiaotong University, Xian Children's Hospital | Autism Spectrum Disorder, Autism in Children | 01/26 | 01/26 | | |
NCT06839378: Flura-seq for Evaluating the Effects of Different Hyperthermic Intraperitoneal Chemotherapy Regimens on the Transcriptome of Pseudomyxoma Peritonei |
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| Completed | N/A | 36 | RoW | intravenously inject with 5-FU (400 mg/m2) | Beijing Tsinghua Chang Gung Hospital, Tsinghua University | Pseudomyxoma Peritonei | 08/25 | 10/25 | | |
ELEVATE-AF, NCT06883864: Efficacy and Safety of Catheter abLation in patiEnts With seVere mitrAl regurgiTation and pErsistent Atrial Fibrillation: a Randomized Controlled Trial |
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| Recruiting | N/A | 146 | RoW | Catheter ablation plus medication, Medication, (ELEVATE-AF X) experimental group, (ELEVATE-AF X) control group | Beijing Anzhen Hospital, Abbott | Atrial Fibrillation (AF), Catheter Ablation, Atrial Functional Mitral Regurgitation | 08/27 | 05/28 | | |
NCT07073144: The Impact of 'Digital Strolling' on Depression and Quality of Life of People With Severe Mobility Impairment |
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| Completed | N/A | 24 | RoW | Virtual walking, Passive observing walking | The Hong Kong Polytechnic University | Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete), Poliomyelitis | 10/25 | 10/25 | | |
NCT05282095: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China |
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| Recruiting | N/A | 300 | RoW | Follow up | Fujian Maternity and Child Health Hospital | Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions | 12/25 | 05/26 | | |
NCT07170969: A Feasibility Trial of an Enhanced Coping-oriented Supportive Programme for Community-dwelling People With Spinal Cord Injury |
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| Completed | N/A | 12 | RoW | An Enhanced Coping-oriented Supportive Programme (E-COSP) for Community-Dwelling People with Spinal Cord Injury | The Hong Kong Polytechnic University | Spinal Cord Injury, Mental Health, Feasibility Studies, Acceptability Study, Spinal Cord Injuries (SCI), Spinal Cord Injuries, Coping | 09/25 | 09/25 | | |
DISCLOSE, NCT07042139: No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older |
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| Recruiting | N/A | 532 | Europe | No reduction, Closed Reduction, Casting | Tampere University Hospital, Kuopio University Hospital, Viborg Regional Hospital, Karolinska University Hospital, Helsinki University Central Hospital, Tartu University Hospital, Pori Central Hospital, Oulu University Hospital | Distal Radius Fracture, Casting, Closed Reduction | 07/29 | 07/33 | | |
NCT07281300: Mindfulness-Oriented Respiratory Distress Symptom Intervention for Lung Cancer |
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| Recruiting | N/A | 64 | RoW | Mindfulness-Oriented Respiratory Distress Symptom Intervention (M-RDSI), Usual Care | The Hong Kong Polytechnic University | Symptom Cluster, Breathlessness, Coughing, Fatigue Symptom, Lung Cancer Patients, Brain Activity | 06/27 | 07/27 | | |
| Recruiting | N/A | 300 | RoW | Diagnostic biomarker | Shixuan Wang | Uterine Sarcoma | 11/25 | 11/25 | | |
| Recruiting | N/A | 258 | US | | Oregon Health and Science University, National Eye Institute (NEI) | Keratoconus, Irregular; Contour of Cornea | 12/27 | 12/28 | | |
NCT07302672: Humanistic Continuing Care Via WeChat for Patients Undergoing Thermal Ablation of Papillary Thyroid Carcinoma |
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| Recruiting | N/A | 108 | RoW | Humanistic Continuing Care via WeChat, Usual Care (No Structured WeChat Program) | Ming-an Yu | Papillary Thyroid Carcinoma | 06/26 | 12/26 | | |
NCT04995159: Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System |
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| Not yet recruiting | N/A | 2150 | RoW | Single anti-platelet therapy, SAPT strategy, Dual anti-platelet therapy, DAPT strategy | Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Heart Disease | 01/26 | 01/28 | | |
NCT07505940: Bilateral Comparison of Unilateral Sacral Neuromodulation Test Stimulation in the Treatment of Neurogenic Bladder |
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| Not yet recruiting | N/A | 29 | RoW | bilateral sacral nerve stimulation (BNS) | Qilu Hospital of Shandong University | Neurogenic Bladder | 03/27 | 03/27 | | |
| Recruiting | N/A | 287 | Europe | Surgical treatment, Non-surgical treatment | Kolding Sygehus, Copenhagen University Hospital, Hvidovre, Zealand University Hospital, Oslo University Hospital, Helse Stavanger HF, Sahlgrenska University Hospital, Sweden, Uppsala University Hospital, Odense University Hospital, Hospital of Southern Jutland, Slagelse Hospital, Aalborg University Hospital, University Hospital, Umeå, Nordsjaellands Hospital, Holbaek Sygehus, Aarhus University Hospital, Copenhagen University Hospital, Herlev-Gentofte, University Hospital Bispebjerg and Frederiksberg, Viborg Regional Hospital, Karolinska University Hospital, Danderyd Hospital, Tampere University Hospital, Helsinki University Central Hospital | Fracture Humerus of Shaft | 12/25 | 07/31 | | |
NCT05858944: Home Blood Pressure Intervention in the Community Trial |
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| Recruiting | N/A | 10000 | RoW | Intensive Home BP control, Home BP<125/75 mmHg, Standard Home BP control, Home BP<135/85 mmHg | Shanghai Institute of Hypertension | Home Blood Pressure | 12/29 | 06/30 | | |
| Recruiting | N/A | 450 | RoW | Healthy control specimen collection, Non-Borrmann IV patient specimen collection, Borrmann IV patient specimen collection | First Hospital of China Medical University, Liaoning Cancer Hospital & Institute, The Second Hospital of Shandong University, The General Hospital of Fushun Mining Bureau, The fourth People's Hospital of Changzhou, The First People's Hospital of Jingzhou | Stomach Neoplasms, Gut Microbiota, Metabolomics | 01/24 | 12/25 | | |
| Recruiting | N/A | 500 | RoW | YISAIPU® ( An etanercept biosimilar), a recombinant tumor necrosis factor receptor-Fc fusion protein, rhTNFR:Fc, csDMARDs | The First Affiliated Hospital of Xiamen University | Rheumatoid Arthritis | 06/25 | 12/25 | | |
| Liu, Yang |
NCT05694585: Effect of Esmolol on Perioperative Stress Reaction |
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| Not yet recruiting | 4 | 46 | NA | Esmolol, Esmolol hydrochloride, saline, 0.9% sodium chloride injection solution | Xiumei Song | Esmolol, Stress Reaction, Airway Obstruction, Catecholamine; Overproduction | 12/23 | 12/23 | | |
NCT07309562: The Efficacy and Safety of Inpegsomatropin Injection in Children With Short Stature Born Small for Gestational Age |
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| Recruiting | 3 | 141 | RoW | Inpegsomatropin Injection, Recombinant Human Growth Hormone Injection | Xiamen Amoytop Biotech Co., Ltd. | Small for Gestational Age | 03/28 | 05/28 | | |
| Recruiting | 3 | 1400 | Europe, Canada, US, RoW | Ribociclib, LEE011, Letrozole, Ansastrozole, Goserelin, Leuprolide, Exemestane | Novartis Pharmaceuticals, Novartis Pharma AG | Early Breast Cancer | 09/29 | 09/30 | | |
NCT03989336: A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer |
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| Completed | 2 | 84 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Platinum chemotherapy, Sintilimab, anti-PD-1 antibody; PD-1 inhibitor | Chinese PLA General Hospital | Ovarian Cancer | 05/22 | 12/23 | | |
NCT06404840: Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study |
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| Recruiting | 2 | 30 | RoW | nimotuzumab, AG chemotherapy | Tianjin Medical University Cancer Institute and Hospital | Pancreatic Cancer | 03/25 | 05/26 | | |
NCT03250962: SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma |
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| Recruiting | 2 | 280 | RoW | SHR-1210, Decitabine | Chinese PLA General Hospital | Hodgkin Lymphoma | 07/22 | 03/25 | | |
NCT04514081: The Clinical Trial of Chidamide+Decitabine+Camrelizumab Versus Decitabine+Camrelizumab in Anti-PD-1 Antibody Resistant Patients With Classical Hodgkin Lymphoma. |
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| Recruiting | 2 | 200 | RoW | Chidamide; Decitabine; Camrelizumab, Decitabine+Camrelizumab | Chinese PLA General Hospital | Hodgkin Lymphoma, Anti-PD-1 Antibody Resistant | 08/22 | 08/25 | | |
NCT06586697: First-line Treatment for ES-SCLC with Chemotherapy Combined with PD-1/PD-L1 Inhibitor Sequential Thoracic Radiotherapy |
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| Recruiting | 2 | 47 | RoW | Thoracic Radiotherapy | Henan Cancer Hospital | Extensive-stage Small-cell Lung Cancer | 01/26 | 03/26 | | |
CHN-PLAGH-BT-045, NCT04233294: Addition of Chidamide to the Combination Treatment of Decitabine Plus Camrelizumab in Combination Treatment Resistant/Relapsed Patients With Classical Hodgkin Lymphoma |
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| Recruiting | 2 | 100 | RoW | Chidamide, Camrelizumab, Decitabine | Chinese PLA General Hospital | Hodgkin Lymphoma | 02/24 | 02/26 | | |
| Recruiting | 2 | 30 | RoW | Ivonescimab（AK112，a PD-1/VEGF bispecific antibody）, HAIC | Tianjin Medical University Cancer Institute and Hospital | Hepatocellular Carcinoma Non-resectable, Hepatocellular Carcinoma | 03/25 | 06/26 | | |
OBU-HCC-II-001, NCT06405061: Evaluation of Effectiveness and Safety of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma |
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| Suspended | 2 | 40 | RoW | Adebrelimab, Bevacizumab, HAIC | Tianjin Medical University Cancer Institute and Hospital | Adebrelimab, Hepatocellular Carcinoma | 05/27 | 08/28 | | |
NCT06342466: Bortezomib, Pomalidomide, Dexamethasone for Systemic AL Amyloidosis |
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| Recruiting | 2 | 40 | RoW | Bortezomib, Velcade, Pomalidomide, Dexamethasone | Jin Lu, MD | Systemic Amyloidosis | 12/26 | 12/26 | | |
NCT06418477: Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients with MIDD |
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| Recruiting | 2 | 20 | RoW | Dara-CyBorD | Peking University People's Hospital | Monoclonal Gammopathy of Renal Significance | 12/25 | 12/26 | | |
NCT06606483: A Study to Evaluate the Efficacy and Safety of MDR-001 in Subjects Who Are Obesity or Overweight |
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| Not yet recruiting | 2 | 300 | RoW | MDR-001, Placebo | MindRank AI Ltd | Obesity, Overweight and Obesity | 07/25 | 09/25 | | |
NCT06890858: A Clinical Study on Fasudil Hydrochloride for Treatment of Gene-Specific Ovarian Cancer |
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| Recruiting | 2 | 20 | RoW | Fasudil Hydrochloride | Zhejiang Provincial People's Hospital | Ovarian Cancer | 01/28 | 01/28 | | |
NCT06558773: GSL Synthetase Inhibitor Plus Immune Checkpoint Inhibitor and/or Regorafenib in Previously Treated pMMR/MSS CRC. |
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| Recruiting | 2 | 120 | RoW | Regorafenib+Immune checkpoint inhibitor, Regorafenib(Stivarga), Eliglustat+Immune checkpoint inhibitor, Eliglustat(Cerdelga), Eliglustat+Immune checkpoint inhibitor +Regorafenib | Chinese PLA General Hospital | Colorectal Cancer | 03/27 | 03/29 | | |
NCT02961101: Anti-PD-1 Antibody Alone or in Combination With Decitabine/Chemotherapy in Relapsed or Refractory Malignancies |
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| Recruiting | 1/2 | 250 | RoW | Anti-PD-1 antibody, Decitabine, Chemotherapy | Han weidong | Malignancies Multiple | 05/26 | 05/26 | | |
NCT03989310: An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer |
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| Recruiting | 1/2 | 50 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Gemcitabine, anti-PD-1 antibody, Anti-PD-1 monoclonal antibody; PD-1 inhibitor | Chinese PLA General Hospital | Pancreatic Cancer | 05/21 | 03/22 | | |
NCT04553393: Decitabine-primed Tandem CD19/CD20 CAR T Cells Plus Epigenetic Agents in Aggressive r/r B-NHL With Huge Tumor Burden |
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| Recruiting | 1/2 | 80 | RoW | Chidamide, cohort 2, Decitabine, cohort 3, Chidamide and Decitabine, cohort 4, Decitabine-primed Tandem CAR19/20 engineered T cells, cohort 1 | Chinese PLA General Hospital | Refractory or Relapsed Aggressive r/r B-NHL With Huge Tumor Burden | 09/21 | 09/22 | | |
NCT04588324: Study of SHR2150 (TLR7 Agonist) in Combination With Chemotherapy Plus PD-1 or CD47 Antibody in Subjects With Unresectable/ Metastatic Solid Tumors |
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| Recruiting | 1/2 | 50 | RoW | SHR2150, Anti-Cancer Agent | Chinese PLA General Hospital | Solid Tumor | 11/21 | 11/22 | | |
NCT04897477: Azacytidine, Bendamustine, Piamprizumab in Refractory/Relapsed B-cell Non-Hodgkin's Lymphoma |
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| Recruiting | 1/2 | 30 | RoW | Azacytidine, Bendamustine and Piamprizumab | Chinese PLA General Hospital | Non-hodgkin Lymphoma,B Cell | 04/22 | 04/23 | | |
NCT04873440: An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma |
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| Recruiting | 1/2 | 10 | RoW | Manganese Chloride, Mn2+, Radiotherapy, Chemo-immunotherapy | Chinese PLA General Hospital | Solid Tumor, Lymphoma | 05/22 | 05/23 | | |
NCT04697940: Decitabine-primed Tandem CD19/CD20 CAR T Cells Treatment in r/r B-NHL |
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| Active, not recruiting | 1/2 | 33 | RoW | Decitabine-primed Tandem CAR19/20 engineered T cells, Fludarabine, Fludarabine Phosphate for Injection, Cyclophosphamide, Cyclophosphamide for Injection | Han weidong | Relapsed and Refractory B-cell Non-Hodgkin's Lymphoma, Decitabine-primed Tandem CD19/CD20 CAR T Cells | 05/25 | 09/26 | | |
NCT06321289: Allogeneic TRAC Locus-inserted CD19-targeting STAR T Cell Therapy in r/r B-NHL |
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| Recruiting | 1/2 | 30 | RoW | Allogeneic CD19-STAR T cell, Allogeneic CD19-targeting synthetic T-cell receptor antigen receptor T cells, Fludarabine, Fludarabine Phosphate for Injection, Cyclophosphamide, Cyclophosphamide for Injection | Chinese PLA General Hospital | Non-hodgkin Lymphoma,B Cell | 03/26 | 03/27 | | |
NCT04337606: Chidamide in Combination With Decitabine in Non-Hodgkin's Lymphoma Relapsed After Chimeric Antigen Receptor |
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| Recruiting | 1/2 | 100 | RoW | Chidamide, Decitabine, Camrelizumab | Chinese PLA General Hospital | Non Hodgkin Lymphoma | 04/24 | 04/26 | | |
NCT06323525: TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma |
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| Recruiting | 1/2 | 30 | RoW | TCR reserved and Power3 (SPPL3) gene knock-out allogeneic CD19-targeting CAR-T cell (ATHENA-2 CAR-T), Fludarabine, Fludarabine Phosphate for Injection, Cyclophosphamide, Cyclophosphamide for Injection | Chinese PLA General Hospital | Non-hodgkin Lymphoma | 04/26 | 04/27 | | |
NCT05631912: TRAC Locus-inserted CD19-targeting STAR-T Cell Therapy in r/r B-NHL |
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| Recruiting | 1/2 | 38 | RoW | Autologous CD19-STAR-T cell, Autologous CD19-targeting synthetic T-cell receptor antigen receptor T cells, Fludarabine, Fludarabine Phosphate for Injection, Cyclophosphamide, Cyclophosphamide for Injection | Chinese PLA General Hospital | Non-hodgkin Lymphoma,B Cell | 12/24 | 12/25 | | |
