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 30 Trials 
80 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Baldus, Stephan
NCT02732704: THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

Active, not recruiting
N/A
100
Europe, US
JenaValve Pericardial TAVR System
JenaValve Technology, Inc.
Aortic Regurgitation
08/22
09/27
AHEAD, NCT03339115: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System

Recruiting
N/A
30
Europe
Cardiovalve Transfemoral Mitral Valve
Cardiovalve Ltd., Meditrial Europe Ltd., Meditrial SrL
Mitral Regurgitation, Mitral Valve Disease
12/24
12/29
TriCLASP, NCT04614402: Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System

Active, not recruiting
N/A
300
Europe
Edwards PASCAL Transcatheter Valve Repair System, Edwards PASCAL Precision Transcatheter Valve Repair System
Edwards Lifesciences
Tricuspid Valve Insufficiency
04/23
03/28
TAVIS, NCT05536310: Registry - Trilogy Heart Valve System for Management of Patients With Aortic Valve Disease

Not yet recruiting
N/A
600
Europe
Transcatheter Aortic Valve Implantation (TAVI)
JenaValve Technology, Inc.
Aortic Valve Stenosis, Aortic Valve Regurgitation, Aortic Valve Stenosis With Insufficiency, Constriction, Pathologic, Aortic Valve Disease, Heart Valve Diseases, Cardiovascular Diseases in Old Age, Ventricular Outflow Obstruction, Aortic Stenosis, Severe
10/23
10/27
MiCLASP, NCT04430075: Post Market Clinical Follow-Up (PMCF) Study

Recruiting
N/A
1000
Europe
Edwards PASCAL Transcatheter Valve Repair System and Edwards PASCAL Precision Transcatheter Valve Repair System
Edwards Lifesciences
Mitral Regurgitation, Mitral Insufficiency
02/25
04/30
MiBAND, NCT03600688: Edwards Cardioband European Post-Market Study,

Active, not recruiting
N/A
200
Europe
Edwards Cardioband System
Edwards Lifesciences
Mitral Regurgitation, Mitral Insufficiency, Mitral Repair, Mitral Valve, Annuloplasty, Edwards Cardioband
12/23
12/23
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT04482062: TRISCEND II Pivotal Trial

Active, not recruiting
N/A
1070
Europe, US
Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
06/24
12/29
RESOLVE-MR, NCT04818502: Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation

Active, not recruiting
N/A
200
Europe, RoW
Tendyne™ Mitral Valve System, Transcatheter Mitral Valve Implantation (TMVI)
Abbott Medical Devices
Mitral Valve Regurgitation
05/25
05/29
TRICI-HF, NCT04634266: TRICuspid Intervention in Heart Failure Trial

Recruiting
N/A
360
Europe
Transcatheter tricuspid valve treatment (TTVT)
LMU Klinikum, Heart and Diabetes Center North Rhine-Westphalia, University Medical Center Mainz, Heart Center Leipzig - University Hospital, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), University of Leipzig
Heart Failure Attributable to Severe Tricuspid Regurgitation
03/26
03/27
NCT05851209: Biomarkers and Mechanisms of Disease Progression and Outcome of Aortic Stenosis in Humans

Not yet recruiting
N/A
938
Europe
Heinrich-Heine University, Duesseldorf, German Research Foundation, University Bonn, University Cologne, Collaborative Research Center
Aortic Stenosis, Imaging, Pathogenesis, Disease Progression, Aortic Valve Calcification, Genetics
07/26
07/31
TENDER, NCT04898335: Tendyne European Experience Registry

Recruiting
N/A
400
Europe
Tendyne Mitral Valve System
Klinikum der Universitaet Muenchen
Mitral Regurgitation
12/26
12/27
Whisenant, Brian
ACTIVE, NCT03016975: Edwards Cardioband System Pivotal Clinical Trial

Terminated
N/A
12
US
Edwards Cardioband System, Transcatheter mitral valve repair (TMVr), Guideline Directed Medical Therapy
Edwards Lifesciences
Functional Mitral Regurgitation, Mitral Regurgitation, Mitral Insufficiency
07/19
09/22
NCT03904147: TRILUMINATE Pivotal Trial

Active, not recruiting
N/A
572
Europe, Canada, US
TriClipTM Device
Abbott Medical Devices
Tricuspid Regurgitation
11/22
04/29
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

Active, not recruiting
N/A
178
Europe, Canada, US
SAPIEN 3 THV, Optimal Heart Failure Therapy
Cardiovascular Research Foundation, New York, Cardialysis BV, Avania
Aortic Valve Stenosis
02/23
02/25
PARADIGM, NCT04489823: Amplatzer Valvular Plug for PVL Closure

Recruiting
N/A
200
Europe, Canada, US
AVP III
Abbott Medical Devices
Paravalvular Aortic Regurgitation
07/25
06/26
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT04820764: EFS of the CardioMech MVRS

Recruiting
N/A
25
US
CardioMech MVRS
CardioMech AS
Mitral Regurgitation
12/25
12/30
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
NCT04482062: TRISCEND II Pivotal Trial

Active, not recruiting
N/A
1070
Europe, US
Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
06/24
12/29
TRICAV, NCT06137807: TRIcvalve BiCAVal Valve System for Severe Tricuspid Regurgitation (-I)

Recruiting
N/A
15
US
TricValve® Transcatheter Bicaval Valve System, TricValve System
P+F Products + Features USA Inc., P+F Products + Features GmbH, Meditrial USA Inc.
Tricuspid Regurgitation, Tricuspid Valve Disease
11/25
09/29
NCT05809596: HEAL-LAA Clinical Trial

Active, not recruiting
N/A
949
US
WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure
Boston Scientific Corporation
Atrial Fibrillation, Bleeding, Stroke
07/24
08/25
MITRAL-II, NCT04408430: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Recruiting
N/A
210
US
Transseptal ViMAC, ViMAC
Mayra Guerrero
Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease
12/24
12/24
CLASP II TR, NCT04097145: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Recruiting
N/A
870
Canada, US
Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
12/27
12/31
NCT03382457: Clinical Study of Edwards Cardioband FIT Valve Repair System

Recruiting
N/A
55
US
Transcatheter Tricuspid Valve Repair, Edwards Cardioband Tricuspid Valve Repair
Edwards Lifesciences
Tricuspid Regurgitation
12/26
12/31
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
Weiner, Matthew
NCT05048966: Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons

Recruiting
N/A
360
US
Group Wellness Class 1, Group Wellness Class 2
Kessler Foundation, University of Michigan, Franciscan Health, Rehabilitation Hospital of Indiana, University of California, San Diego
Traumatic Brain Injury, Mild Traumatic Brain Injury, Alzheimer's Disease, Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe, Dementia
09/25
09/25
Eng, Marvin H
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

Active, not recruiting
N/A
1948
Canada, US
ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL
Boston Scientific Corporation
Aortic Stenosis
06/24
09/34
SAVE, NCT04372381: Supra-Annular vs. Annular ValvEs for Small Annuli

Enrolling by invitation
N/A
150
US
Transcatheter aortic valve replacement (Edwards Sapien Ultra or Medtronic Evolut Pro
Marvin Eng, William Beaumont Hospitals
Aortic Valve Stenosis, Implantation, Heart Valve Prosthesis
11/24
06/25
MITRAL-II, NCT04408430: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Recruiting
N/A
210
US
Transseptal ViMAC, ViMAC
Mayra Guerrero
Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease
12/24
12/24
CLASP II TR, NCT04097145: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Recruiting
N/A
870
Canada, US
Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
12/27
12/31
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
Calles, Natalia E
RECOVER, NCT04470544: Camostat Mesilate Treating Patients With Hospitalized Patients With COVID-19

Completed
2
100
US
Camostat Mesilate, Foipan, Standard of Care
Alan Bryce
Severe Acute Respiratory Syndrome
12/21
01/22
NCT04465981: Investigation of Antibody and Immune Responses to SARS-CoV-2 Proteins in COVID-19 Patients

Recruiting
N/A
80
US
Sampling
INanoBio Inc., TMC HealthCare
COVID-19, SARS-CoV-2 Infection
06/22
12/22
NCT03904147: TRILUMINATE Pivotal Trial

Active, not recruiting
N/A
572
Europe, Canada, US
TriClipTM Device
Abbott Medical Devices
Tricuspid Regurgitation
11/22
04/29
DurAVRâ„¢ EFS, NCT05712161: Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study

Active, not recruiting
N/A
15
US
DurAVRTM THV System
Anteris Technologies Ltd.
Aortic Stenosis, Symptomatic Aortic Stenosis, Severe Aortic Valve Stenosis, Aortic Valve Calcification
12/23
12/33
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
NCT05565599: An Early Feasibility Study Evaluating the Safety and Efficacy of the Laminar Left Atrial Appendage Closure System in Subjects With Non-Valvular Atrial Fibrillation

Active, not recruiting
N/A
45
US
Left Atrial Appendage Closure
Laminar, Inc.
Non-valvular Atrial Fibrillation
08/24
09/29
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26
STITCH, NCT04339699: NobleStitch EL Trial is a PFO Comparative Trial

Suspended
N/A
640
Europe, US
NobleStitch™EL Suture Mediated Closure System, Amplatzer PFO Occluder
Nobles Medical Technologies II Inc
Foramen Ovale, Patent, Stroke, Ischemic
12/26
06/27
Waggoner, Thomas
MAvERIC, NCT05494788: Impact of CardiolRxTM on Recurrent Pericarditis (-Pilot)

Completed
2
25
US
CardiolRx
Cardiol Therapeutics Inc.
Recurrent Pericarditis
06/24
09/24
NCT04029337: An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System

Recruiting
N/A
30
US
Transcatheter Mitral Valve Replacement
HighLife SAS
Mitral Regurgitation
12/24
12/27
ECP Study, NCT05334784: Impella () and Impella ECP Continued Access Protocol

Enrolling by invitation
N/A
556
US
Impella ECP
Abiomed Inc.
High-Risk Percutaneous Coronary Intervention
12/25
12/26
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

Active, not recruiting
N/A
1948
Canada, US
ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL
Boston Scientific Corporation
Aortic Stenosis
06/24
09/34
CorCinch-HF, NCT04331769: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF): the CORCINCH-HF Study

Recruiting
N/A
400
Europe, US, RoW
AccuCinch Ventricular Restoration System, Guideline-Directed Medical Therapy
Ancora Heart, Inc.
Heart Failure with Reduced Ejection Fraction (HFrEF), Dilated Cardiomyopathy
12/26
12/30
NCT04482062: TRISCEND II Pivotal Trial

Active, not recruiting
N/A
1070
Europe, US
Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
06/24
12/29
NCT05809596: HEAL-LAA Clinical Trial

Active, not recruiting
N/A
949
US
WATCHMAN FLX Pro LAAC Device, Left Atrial Appendage Closure
Boston Scientific Corporation
Atrial Fibrillation, Bleeding, Stroke
07/24
08/25
SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting
N/A
1857
US
WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device
Boston Scientific Corporation
Atrial Fibrillation, Stroke, Bleeding
07/26
01/27
CATALYST, NCT04226547: Amplatzer Amulet LAAO vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
MITRAL-II, NCT04408430: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).

Recruiting
N/A
210
US
Transseptal ViMAC, ViMAC
Mayra Guerrero
Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease
12/24
12/24
CLASP II TR, NCT04097145: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Recruiting
N/A
870
Canada, US
Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy
Edwards Lifesciences
Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
12/27
12/31
RESONANCE, NCT04687358: REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

Recruiting
N/A
500
US
Kiniksa Pharmaceuticals International, plc, Kiniksa Pharmaceuticals (UK), Ltd.
Recurrent Pericarditis
02/26
02/26
PROTECT IV, NCT04763200: Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

Recruiting
N/A
1252
Europe, Canada, US
Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump
Abiomed Inc.
Left Ventricular Dysfunction, Coronary Artery Disease
03/26
10/27
NCT04198870: MitraClip REPAIR MR Study

Recruiting
N/A
500
Europe, Canada, US
MitraClip™ device implantation, Mitral Valve Repair Surgery
Abbott Medical Devices
Mitral Valve Regurgitation
04/26
04/34
STITCH, NCT04339699: NobleStitch EL Trial is a PFO Comparative Trial

Suspended
N/A
640
Europe, US
NobleStitch™EL Suture Mediated Closure System, Amplatzer PFO Occluder
Nobles Medical Technologies II Inc
Foramen Ovale, Patent, Stroke, Ischemic
12/26
06/27
Lannotti, Joyce Lee
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26
Teeple, David
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26
Gheewala, Neil
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Makki, Nader
NCT05592275: A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

Active, not recruiting
2
456
Europe, Canada, Japan, US, RoW
LY3540378, Placebo
Eli Lilly and Company
Heart Failure, Heart Failure With Preserved Ejection Fraction
01/25
01/25
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Franklin, Gregory
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Katariya, Kushagra
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Elias-Calles, Natalia
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Scott, Katherine
TRIPHASE, NCT06101745: Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery

Recruiting
2/3
336
Europe
Nizaracianine Triflutate, ZW800-1, Placebo Comparator, Sugar
Curadel Surgical Innovations, Inc., Leiden University Medical Center, Erasmus Medical Center
Injury of Ureter During Surgery (Disorder)
10/25
11/25
NCT05128162: Open-label Study to Assess the Safety and Efficacy of Psilocybin With Psychotherapy in Adult Participants With Fibromyalgia

Completed
2
7
US
Psilocybin, Psychotherapy
Kevin Boehnke
Fibromyalgia
06/24
06/24
NCT04465981: Investigation of Antibody and Immune Responses to SARS-CoV-2 Proteins in COVID-19 Patients

Recruiting
N/A
80
US
Sampling
INanoBio Inc., TMC HealthCare
COVID-19, SARS-CoV-2 Infection
06/22
12/22
Vardas, Panayotis
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Marsh, Mary
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
NCT06183684: Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

Recruiting
N/A
10
US
Laplace TTVR System
Laplace Interventional, Inc
Tricuspid Regurgitation
03/25
06/30
SIMPLAAFY, NCT06521463: Clinical Trial

Recruiting
N/A
1857
US
WATCHMAN FLX Pro LAAC Device, WATCHMAN FLX Pro Left Atrial Appendage Closure Device
Boston Scientific Corporation
Atrial Fibrillation, Stroke, Bleeding
07/26
01/27
CATALYST, NCT04226547: Amplatzer Amulet LAAO vs. NOAC

Recruiting
N/A
2650
Europe, Canada, Japan, US, RoW
Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Amplatzer Amulet LAA Occluder, Non-Vitamin K Oral Antagonists, NOAC
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
08/27
08/30
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Recruiting
N/A
300
Europe, US
Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication
Cardiac Dimensions, Inc.
Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
12/26
12/30
Moylen, Karen
SISTER, NCT05948566: Strategy for Improving Stroke Treatment Response

Recruiting
2
300
US
TS23
Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona
Ischemic Stroke
07/27
12/27
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26
Manage, Esha
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial

Recruiting
N/A
1247
Europe, Canada, US
Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System
Edwards Lifesciences
Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation
01/25
04/30
Granados, Karla
Sleep SMART, NCT03812653: Sleep for Stroke Management and Recovery Trial

Recruiting
N/A
3062
US
CPAP
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS), FusionHealth LLC, Medical University of South Carolina, University of Cincinnati
Ischemic Stroke, Sleep Apnea, Sleep Apnea, Obstructive, Stroke, CPAP, Telemedicine, Home Sleep Apnea Test, Randomized Clinical Trial, Multicenter Trial
11/26
11/26

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